KR100547921B1 - 설폰아미드-치환된크로만,이의제조방법및이를포함하는약제학적조성물 - Google Patents

설폰아미드-치환된크로만,이의제조방법및이를포함하는약제학적조성물

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Publication number
KR100547921B1
KR100547921B1 KR1019970018635A KR19970018635A KR100547921B1 KR 100547921 B1 KR100547921 B1 KR 100547921B1 KR 1019970018635 A KR1019970018635 A KR 1019970018635A KR 19970018635 A KR19970018635 A KR 19970018635A KR 100547921 B1 KR100547921 B1 KR 100547921B1
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KR
South Korea
Prior art keywords
chromamann
sulfonamide
substituted
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019970018635A
Other languages
English (en)
Korean (ko)
Other versions
KR19980024020A (ko
Inventor
한스 요헨 랑
우베 게르라크
요아힘 브렌델
하인리히 크리슈티안 엥글레르트
하인즈 괴겔라인
막스 로포트
헬무트 본
안드레아스 헤를링
안드레아스 부쉬
라이너 그레거
Original Assignee
훽스트 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19619614A external-priority patent/DE19619614A1/de
Priority claimed from DE1996139462 external-priority patent/DE19639462A1/de
Application filed by 훽스트 악티엔게젤샤프트 filed Critical 훽스트 악티엔게젤샤프트
Publication of KR19980024020A publication Critical patent/KR19980024020A/ko
Application granted granted Critical
Publication of KR100547921B1 publication Critical patent/KR100547921B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019970018635A 1996-05-15 1997-05-15 설폰아미드-치환된크로만,이의제조방법및이를포함하는약제학적조성물 Expired - Fee Related KR100547921B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19619614A DE19619614A1 (de) 1996-05-15 1996-05-15 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19619614.0 1996-05-15
DE19639462.7 1996-09-26
DE1996139462 DE19639462A1 (de) 1996-09-26 1996-09-26 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
KR19980024020A KR19980024020A (ko) 1998-07-06
KR100547921B1 true KR100547921B1 (ko) 2006-10-19

Family

ID=26025736

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019970018635A Expired - Fee Related KR100547921B1 (ko) 1996-05-15 1997-05-15 설폰아미드-치환된크로만,이의제조방법및이를포함하는약제학적조성물

Country Status (23)

Country Link
EP (1) EP0807629B1 (https=)
JP (1) JP4234798B2 (https=)
KR (1) KR100547921B1 (https=)
CN (1) CN1204134C (https=)
AR (2) AR007115A1 (https=)
AT (1) ATE260909T1 (https=)
AU (1) AU711986B2 (https=)
BR (1) BR9703161A (https=)
CA (1) CA2205477A1 (https=)
CZ (1) CZ149497A3 (https=)
DE (1) DE59711352D1 (https=)
DK (1) DK0807629T3 (https=)
ES (1) ES2218617T3 (https=)
HR (1) HRP970255B1 (https=)
HU (1) HUP9700903A3 (https=)
IL (1) IL120827A (https=)
NO (1) NO315556B1 (https=)
NZ (1) NZ314800A (https=)
PL (1) PL191330B1 (https=)
PT (1) PT807629E (https=)
SK (1) SK283837B6 (https=)
TR (1) TR199700369A2 (https=)
TW (1) TW496866B (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ329200A (en) * 1996-12-16 1999-05-28 Hoechst Ag Sulphonamide substituted quinazoline, isoquinoline, quinoline or benzo[1,3-]oxazine derivatives and medicaments
DE19705133A1 (de) * 1997-02-11 1998-08-13 Hoechst Ag Sulfonamid-substituierte Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0895994A3 (de) * 1997-08-05 1999-12-15 Hoechst Marion Roussel Deutschland GmbH Sulfonamid-substituierte Pyranopyridine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19742508A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19748469A1 (de) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
AU754204B2 (en) * 1998-09-01 2002-11-07 Bristol-Myers Squibb Company Potassium channel inhibitors and method
DE19858253A1 (de) * 1998-12-17 2000-06-21 Aventis Pharma Gmbh Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden
US7368582B2 (en) 2003-10-17 2008-05-06 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them
KR101085979B1 (ko) * 2004-03-23 2011-11-22 닛산 가가쿠 고교 가부시키 가이샤 항부정맥제로 사용되는 삼환계 벤조피란 화합물
US7884109B2 (en) 2005-04-05 2011-02-08 Wyeth Llc Purine and imidazopyridine derivatives for immunosuppression
US7989459B2 (en) 2006-02-17 2011-08-02 Pharmacopeia, Llc Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
TW200837064A (en) 2006-10-04 2008-09-16 Pharmacopeia Inc 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression
TW200831104A (en) 2006-10-04 2008-08-01 Pharmacopeia Inc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
RU2523279C2 (ru) * 2009-04-30 2014-07-20 Ниссан Кемикал Индастриз, Лтд. Новая кристаллическая форма соединения трициклического бензопирана и способ его производства
TWI583677B (zh) * 2012-09-21 2017-05-21 日本臟器製藥股份有限公司 香豆素衍生物
CN103012380B (zh) * 2013-01-10 2015-03-04 山东大学 一种色满类化合物及其制备方法与应用
JP6089055B2 (ja) * 2014-03-20 2017-03-01 日本臓器製薬株式会社 クマリン誘導体を含有する医薬
AR117169A1 (es) 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas
CN115915941B (zh) 2020-05-06 2025-07-15 拜耳公司 作为杀真菌化合物的吡啶（硫代）酰胺
EP4149929B1 (en) 2020-05-12 2026-01-28 Bayer Aktiengesellschaft Triazine and pyrimidine (thio)amides as fungicidal compounds
CN115803317B (zh) 2020-05-19 2025-07-15 拜耳作物科学股份公司 作为杀真菌化合物的氮杂双环(硫代)酰胺
WO2021239766A1 (en) 2020-05-27 2021-12-02 Bayer Aktiengesellschaft Active compound combinations
US20250064060A1 (en) 2021-11-03 2025-02-27 Bayer Aktiengesellschaft Bis(hetero)aryl thioether (thio)amides as fungicidal compounds

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DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof

Non-Patent Citations (1)

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Eur. J. Physiol. (1995), 429: 517-530 (인용문헌) *

Also Published As

Publication number Publication date
IL120827A0 (en) 1997-09-30
EP0807629B1 (de) 2004-03-03
NZ314800A (en) 1999-02-25
DK0807629T3 (da) 2004-05-17
PL191330B1 (pl) 2006-04-28
PT807629E (pt) 2004-07-30
ES2218617T3 (es) 2004-11-16
CZ149497A3 (en) 1997-12-17
SK60397A3 (en) 1998-02-04
AR010314A1 (es) 2000-06-07
CA2205477A1 (en) 1997-11-15
HRP970255B1 (en) 2003-10-31
AU2080697A (en) 1997-11-20
HUP9700903A2 (hu) 1998-12-28
EP0807629A1 (de) 1997-11-19
TR199700369A2 (xx) 1997-12-21
NO315556B1 (no) 2003-09-22
JP4234798B2 (ja) 2009-03-04
ATE260909T1 (de) 2004-03-15
HUP9700903A3 (en) 1999-03-01
CN1169429A (zh) 1998-01-07
JPH1067772A (ja) 1998-03-10
BR9703161A (pt) 1998-09-29
TW496866B (en) 2002-08-01
MX9703534A (es) 1997-11-29
CN1204134C (zh) 2005-06-01
PL319995A1 (en) 1997-11-24
HRP970255A2 (en) 1998-04-30
KR19980024020A (ko) 1998-07-06
IL120827A (en) 2004-12-15
AU711986B2 (en) 1999-10-28
NO972211D0 (no) 1997-05-14
AR007115A1 (es) 1999-10-13
NO972211L (no) 1997-11-17
HU9700903D0 (en) 1997-07-28
HK1006640A1 (en) 1999-03-12
SK283837B6 (sk) 2004-03-02
DE59711352D1 (de) 2004-04-08

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