KR100281606B1 - 중합체-결합 된파클리탁셀 유도체, 이의 제조방법 및 이를 포함하는 약제학적 조성물 - Google Patents

중합체-결합 된파클리탁셀 유도체, 이의 제조방법 및 이를 포함하는 약제학적 조성물 Download PDF

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KR100281606B1
KR100281606B1 KR1019940700488A KR19940700488A KR100281606B1 KR 100281606 B1 KR100281606 B1 KR 100281606B1 KR 1019940700488 A KR1019940700488 A KR 1019940700488A KR 19940700488 A KR19940700488 A KR 19940700488A KR 100281606 B1 KR100281606 B1 KR 100281606B1
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Korean (ko)
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니콜라몬겔리
프란체스코안젤루치
엔리코페센티
안토니오수아라토
지오반니비아솔리
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라파엘라 메텔리
파르마시아 앤드 업존 에스.피.에이
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
KR1019940700488A 1992-06-19 1993-06-07 중합체-결합 된파클리탁셀 유도체, 이의 제조방법 및 이를 포함하는 약제학적 조성물 Expired - Fee Related KR100281606B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9213077.2 1992-06-19
GB929213077A GB9213077D0 (en) 1992-06-19 1992-06-19 Polymerbound taxol derivatives
PCT/EP1993/001433 WO1994000156A1 (en) 1992-06-19 1993-06-07 Polymer-bound paclitaxel derivatives

Publications (1)

Publication Number Publication Date
KR100281606B1 true KR100281606B1 (ko) 2001-02-15

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KR1019940700488A Expired - Fee Related KR100281606B1 (ko) 1992-06-19 1993-06-07 중합체-결합 된파클리탁셀 유도체, 이의 제조방법 및 이를 포함하는 약제학적 조성물

Country Status (25)

Country Link
US (4) US5362831A (https=)
EP (1) EP0600062B1 (https=)
JP (1) JP3693340B2 (https=)
KR (1) KR100281606B1 (https=)
CN (1) CN1041281C (https=)
AT (1) ATE205725T1 (https=)
AU (2) AU659750B2 (https=)
CA (1) CA2112482A1 (https=)
CZ (1) CZ62094A3 (https=)
DE (1) DE69330776T2 (https=)
ES (1) ES2164663T3 (https=)
FI (1) FI940733A0 (https=)
GB (1) GB9213077D0 (https=)
HU (2) HUT67914A (https=)
IL (1) IL106023A (https=)
MX (1) MX9303598A (https=)
MY (1) MY109213A (https=)
NZ (1) NZ253116A (https=)
PL (1) PL173898B1 (https=)
RU (1) RU2130462C1 (https=)
SG (1) SG49248A1 (https=)
TW (1) TW266201B (https=)
UA (1) UA39926C2 (https=)
WO (1) WO1994000156A1 (https=)
ZA (1) ZA934388B (https=)

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