JPWO2020176789A5 - - Google Patents
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- JPWO2020176789A5 JPWO2020176789A5 JP2021550182A JP2021550182A JPWO2020176789A5 JP WO2020176789 A5 JPWO2020176789 A5 JP WO2020176789A5 JP 2021550182 A JP2021550182 A JP 2021550182A JP 2021550182 A JP2021550182 A JP 2021550182A JP WO2020176789 A5 JPWO2020176789 A5 JP WO2020176789A5
- Authority
- JP
- Japan
- Prior art keywords
- pbmcs
- antigen
- modified
- hours
- input
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962812225P | 2019-02-28 | 2019-02-28 | |
| US62/812,225 | 2019-02-28 | ||
| EP19161964.2 | 2019-03-10 | ||
| EP19161964 | 2019-03-11 | ||
| US201962841089P | 2019-04-30 | 2019-04-30 | |
| US62/841,089 | 2019-04-30 | ||
| US201962886799P | 2019-08-14 | 2019-08-14 | |
| US62/886,799 | 2019-08-14 | ||
| US201962933304P | 2019-11-08 | 2019-11-08 | |
| US62/933,304 | 2019-11-08 | ||
| US201962948732P | 2019-12-16 | 2019-12-16 | |
| US62/948,732 | 2019-12-16 | ||
| PCT/US2020/020194 WO2020176789A1 (en) | 2019-02-28 | 2020-02-27 | Delivery of biomolecules to pbmcs to modify an immune response |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022522351A JP2022522351A (ja) | 2022-04-18 |
| JPWO2020176789A5 true JPWO2020176789A5 (https=) | 2023-03-07 |
| JP2022522351A5 JP2022522351A5 (https=) | 2023-03-07 |
| JP7610773B2 JP7610773B2 (ja) | 2025-01-09 |
Family
ID=72238527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021550182A Active JP7610773B2 (ja) | 2019-02-28 | 2020-02-27 | 免疫応答を改変するためのｐｂｍｃへの生体分子の送達 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11692168B2 (https=) |
| EP (1) | EP3931309A4 (https=) |
| JP (1) | JP7610773B2 (https=) |
| KR (1) | KR20210134353A (https=) |
| CN (1) | CN114127267A (https=) |
| AU (1) | AU2020228648A1 (https=) |
| BR (1) | BR112021016903A2 (https=) |
| CA (1) | CA3131701A1 (https=) |
| CL (1) | CL2021002258A1 (https=) |
| CO (1) | CO2021012581A2 (https=) |
| CR (1) | CR20210493A (https=) |
| IL (1) | IL285809A (https=) |
| MX (1) | MX2021010320A (https=) |
| PE (1) | PE20220379A1 (https=) |
| PH (1) | PH12021500033A1 (https=) |
| SG (1) | SG11202109333SA (https=) |
| TW (1) | TWI904084B (https=) |
| WO (1) | WO2020176789A1 (https=) |
| ZA (1) | ZA202106308B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3344575B1 (en) | 2015-09-04 | 2020-04-15 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to cells comprising a cell wall |
| JP7602702B2 (ja) | 2016-05-03 | 2024-12-19 | ステムセル テクノロジーズ カナダ インコーポレーテッド | 寛容性を誘導するための生体分子の細胞内送達 |
| US12599656B2 (en) | 2018-03-12 | 2026-04-14 | Stemcell Technologies Canada Inc. | Methods for treating HPV-associated diseases |
| CA3131701A1 (en) * | 2019-02-28 | 2020-09-03 | Sqz Biotechnologies Company | Delivery of biomolecules to pbmcs to modify an immune response |
| US11679388B2 (en) | 2019-04-08 | 2023-06-20 | Sqz Biotechnologies Company | Cartridge for use in a system for delivery of a payload into a cell |
| JP2022533956A (ja) | 2019-05-14 | 2022-07-27 | プロメテウス バイオサイエンシーズ，インク． | Ｔｌ１ａ患者を選択する方法、システム、およびデバイス |
| AU2021272340A1 (en) * | 2020-05-11 | 2022-12-08 | F. Hoffmann-La Roche Ag | Combination therapy with modified pbmcs and an immunoconjugate |
| KR20230079066A (ko) * | 2020-09-02 | 2023-06-05 | 에스큐지 바이오테크놀로지스 컴퍼니 | 유핵 세포를 사용하여 단백질에 대한 hla-불문 면역 반응을 자극하는 방법 |
| TW202241466A (zh) * | 2020-12-29 | 2022-11-01 | 美商Ｓｑｚ生物科技公司 | 以經修飾ｐｂｍｃ治療癌症之方法 |
| JP2024503279A (ja) * | 2020-12-29 | 2024-01-25 | スクイーズ バイオテクノロジーズ カンパニー | Ｐｂｍｃの凍結保存のための製剤 |
| US20220233676A1 (en) | 2020-12-29 | 2022-07-28 | Sqz Biotechnologies Company | Formulations of activating antigen carriers |
| US20220296691A1 (en) * | 2020-12-29 | 2022-09-22 | Sqz Biotechnologies Company | Methods for treating cancer with activating antigen carriers |
| US20240182851A1 (en) * | 2021-04-02 | 2024-06-06 | Sqz Biotechnologies Company | Reprogramming of cells and uses thereof |
| AU2022314616A1 (en) * | 2021-07-19 | 2024-02-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Cellular therapies for cancer by inhibition of monocarboxylate transporter 11 |
| WO2023010090A1 (en) | 2021-07-29 | 2023-02-02 | Sqz Biotechnologies Company | Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery |
| WO2023087009A1 (en) | 2021-11-11 | 2023-05-19 | Sqz Biotechnologies Company | Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery |
| CA3262748A1 (en) | 2022-07-28 | 2024-02-01 | Stemcell Technologies Canada Inc. | IMPROVED ANTIGEN-PRESENTING CELL FORMULATIONS |
| CA3262756A1 (en) | 2022-07-28 | 2024-02-01 | Stemcell Technologies Canada Inc. | CANCER TREATMENT METHODS WITH ENHANCED ANTIGEN-PRESENTING CELLS |
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| DE2502621C3 (de) | 1975-01-23 | 1978-09-14 | Kernforschungsanlage Juelich Gmbh, 5170 Juelich | Messung elastischer und dielektrischer Eigenschaften der Membran lebender Zellen |
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| FR2569477B1 (fr) | 1984-08-24 | 1987-01-02 | Descartes Universite Rene | Appareil et procede pour la determination de la deformabilite des globules rouges du sang |
| JP2720161B2 (ja) | 1988-02-01 | 1998-02-25 | 株式会社アドバンス | 細胞変形能測定装置 |
| JP2685544B2 (ja) | 1988-11-11 | 1997-12-03 | 株式会社日立製作所 | 血液フィルタおよび血液検査方法並びに血液検査装置 |
| JP2532707B2 (ja) | 1990-03-08 | 1996-09-11 | 佑二 菊池 | 血液回路及びこれを用いた血液測定装置及び血液測定方法 |
| AU2002252073A1 (en) | 2001-02-22 | 2002-09-12 | The Scepens Eye Research Institute, Inc. | Tolerogenic antigen presenting cells and in treating immune-inflammatory conditions |
| IL160157A0 (en) | 2001-08-17 | 2004-07-25 | Coley Pharm Group Inc | Combination motif immune stimulation oligonucleotides with improved activity |
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| EP1411351A4 (en) | 2002-06-05 | 2010-07-07 | Panasonic Corp | DEVICE FOR MEASURING THE EXTRACELLULAR POTENTIAL AND METHOD FOR PRODUCING THE DEVICE |
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| CN100591761C (zh) | 2004-08-19 | 2010-02-24 | 加的夫大学学院咨询有限公司 | 呈递抗原的人γδT细胞的制备和在免疫治疗中的用途 |
| US20060134772A1 (en) | 2004-11-18 | 2006-06-22 | The Regents Of The University Of California | System for locating cells and for cellular analysis |
| US7704743B2 (en) | 2005-03-30 | 2010-04-27 | Georgia Tech Research Corporation | Electrosonic cell manipulation device and method of use thereof |
| EP3263581B2 (en) | 2005-05-17 | 2025-07-09 | University of Connecticut | Compositions and methods for immunomodulation in an organism |
| WO2007067032A1 (en) | 2005-12-09 | 2007-06-14 | Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
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| US20080311140A1 (en) | 2007-05-29 | 2008-12-18 | Baylor College Of Medicine | Antigen specific immunosuppression by dendritic cell therapy |
| FR2919804B1 (fr) | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
| GB0718160D0 (en) | 2007-09-18 | 2007-10-24 | Medical Res Council | Methods |
| EP2216639A4 (en) | 2007-11-28 | 2014-01-15 | Konica Minolta Opto Inc | APPARATUS AND METHOD FOR MEASURING BLOOD FLUIDITY |
| US20090280518A1 (en) | 2008-05-12 | 2009-11-12 | Massachusetts Institute Of Technology | System for high throughput measurement of mechanical properties of cells |
| JP5137129B2 (ja) | 2008-07-23 | 2013-02-06 | 国立大学法人山口大学 | 血液細胞の力学的特性測定装置 |
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| US20110300205A1 (en) | 2009-07-06 | 2011-12-08 | Novartis Ag | Self replicating rna molecules and uses thereof |
| US9364831B2 (en) | 2009-08-08 | 2016-06-14 | The Regents Of The University Of California | Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting |
| HRP20161223T1 (hr) | 2009-10-27 | 2016-11-18 | Erytech Pharma | Pripravak za induciranje specifične imune tolerancije |
| EP2516320A4 (en) | 2009-12-23 | 2015-03-04 | Cytovera Inc | SYSTEM AND METHOD FOR PARTICLE FILTRATION |
| US20110293558A1 (en) | 2010-03-22 | 2011-12-01 | Massachusetts Institute Of Technology | Material properties of t cells and related methods and compositions |
| ES2924027T3 (es) | 2010-11-25 | 2022-10-04 | Imcyse Sa | Péptidos inmunogénicos para su uso en la prevención y/o tratamiento de enfermedades infecciosas, enfermedades autoinmunitarias, respuestas inmunitarias a alofactores, enfermedades alérgicas, tumores, rechazo de injerto y respuestas inmunitarias contra vectores virales usados para terapia génica o vacunación génica |
| CN107058101B (zh) | 2011-10-17 | 2021-06-01 | 麻省理工学院 | 细胞内传递 |
| JP2015520194A (ja) | 2012-06-07 | 2015-07-16 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 薬物標的指向化のためのナノ療法 |
| AU2014248119B2 (en) | 2013-04-03 | 2019-06-20 | Memorial Sloan-Kettering Cancer Center | Effective generation of tumor-targeted T-cells derived from pluripotent stem cells |
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| EP3033184B1 (en) | 2013-08-16 | 2021-03-31 | Massachusetts Institute of Technology | Selective delivery of material to cells |
| JP7523203B2 (ja) * | 2014-10-31 | 2024-07-26 | マサチューセッツ インスティテュート オブ テクノロジー | 生体分子の免疫細胞への送達 |
| WO2016077761A1 (en) | 2014-11-14 | 2016-05-19 | Massachusetts Institute Of Technology | Disruption and field enabled delivery of compounds and compositions into cells |
| CN107250373A (zh) | 2015-01-12 | 2017-10-13 | 麻省理工学院 | 通过微流体递送实现的基因编辑 |
| SG10201912910PA (en) | 2015-07-09 | 2020-02-27 | Massachusetts Inst Technology | Delivery of materials to anucleate cells |
| ES2930017T3 (es) | 2015-09-04 | 2022-12-05 | Sqz Biotechnologies Co | Suministro intracelular de biomoléculas mediado por una superficie con poros |
| EP3344575B1 (en) | 2015-09-04 | 2020-04-15 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to cells comprising a cell wall |
| EP3397263B1 (en) | 2015-12-30 | 2023-09-20 | Celgene Corporation | T lymphocyte production methods and t lymphocytes produced thereby |
| CN108779475A (zh) | 2016-01-12 | 2018-11-09 | Sqz生物技术公司 | 复合物的细胞内递送 |
| JP7602702B2 (ja) | 2016-05-03 | 2024-12-19 | ステムセル テクノロジーズ カナダ インコーポレーテッド | 寛容性を誘導するための生体分子の細胞内送達 |
| KR102490952B1 (ko) | 2016-05-03 | 2023-01-19 | 에스큐지 바이오테크놀로지스 컴퍼니 | 관용을 유도하는 생체분자의 세포내 전달 |
| US11422127B2 (en) * | 2016-12-07 | 2022-08-23 | Albany Medical College | Ex vivo antigen and adjuvant pulsed peripheral blood mononuclear cells as a screening platform for candidate novel vaccines and candidate antigens |
| EP3720878A1 (en) | 2017-12-05 | 2020-10-14 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to modulate antibody production |
| JP2021506309A (ja) | 2017-12-20 | 2021-02-22 | スクイーズ バイオテクノロジーズ カンパニー | 細胞の中へのペイロードの送達のためのシステム |
| EP3765068A2 (en) | 2018-03-12 | 2021-01-20 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to modify immune response |
| US12599656B2 (en) | 2018-03-12 | 2026-04-14 | Stemcell Technologies Canada Inc. | Methods for treating HPV-associated diseases |
| KR20210070338A (ko) | 2018-10-04 | 2021-06-14 | 에스큐지 바이오테크놀로지스 컴퍼니 | 항원 제시 세포 기능을 증진시키기 위한 생체분자의 세포내 전달 |
| WO2020154696A1 (en) | 2019-01-25 | 2020-07-30 | Sqz Biotechnologies Company | Anucleate cell-derived vaccines |
| CA3131701A1 (en) | 2019-02-28 | 2020-09-03 | Sqz Biotechnologies Company | Delivery of biomolecules to pbmcs to modify an immune response |
| US11679388B2 (en) | 2019-04-08 | 2023-06-20 | Sqz Biotechnologies Company | Cartridge for use in a system for delivery of a payload into a cell |
-
2020
- 2020-02-27 CA CA3131701A patent/CA3131701A1/en active Pending
- 2020-02-27 EP EP20762663.1A patent/EP3931309A4/en active Pending
- 2020-02-27 BR BR112021016903A patent/BR112021016903A2/pt not_active IP Right Cessation
- 2020-02-27 CN CN202080031336.8A patent/CN114127267A/zh active Pending
- 2020-02-27 WO PCT/US2020/020194 patent/WO2020176789A1/en not_active Ceased
- 2020-02-27 US US16/803,937 patent/US11692168B2/en active Active
- 2020-02-27 PE PE2021001420A patent/PE20220379A1/es unknown
- 2020-02-27 KR KR1020217030867A patent/KR20210134353A/ko active Pending
- 2020-02-27 JP JP2021550182A patent/JP7610773B2/ja active Active
- 2020-02-27 MX MX2021010320A patent/MX2021010320A/es unknown
- 2020-02-27 AU AU2020228648A patent/AU2020228648A1/en active Pending
- 2020-02-27 SG SG11202109333SA patent/SG11202109333SA/en unknown
- 2020-02-27 CR CR20210493A patent/CR20210493A/es unknown
- 2020-02-27 PH PH1/2021/500033A patent/PH12021500033A1/en unknown
- 2020-02-27 TW TW109106460A patent/TWI904084B/zh active
-
2021
- 2021-08-23 IL IL285809A patent/IL285809A/en unknown
- 2021-08-26 CL CL2021002258A patent/CL2021002258A1/es unknown
- 2021-08-30 ZA ZA2021/06308A patent/ZA202106308B/en unknown
- 2021-09-24 CO CONC2021/0012581A patent/CO2021012581A2/es unknown
-
2023
- 2023-05-17 US US18/318,842 patent/US20240228956A9/en active Pending
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