JP2021517813A5 - - Google Patents

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Publication number
JP2021517813A5
JP2021517813A5 JP2020548778A JP2020548778A JP2021517813A5 JP 2021517813 A5 JP2021517813 A5 JP 2021517813A5 JP 2020548778 A JP2020548778 A JP 2020548778A JP 2020548778 A JP2020548778 A JP 2020548778A JP 2021517813 A5 JP2021517813 A5 JP 2021517813A5
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JP
Japan
Prior art keywords
cells
modified
antigen
adjuvant
input
Prior art date
Application number
JP2020548778A
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English (en)
Japanese (ja)
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JPWO2019178006A5 (https=
JP7595827B2 (ja
JP2021517813A (ja
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Priority claimed from PCT/US2019/021705 external-priority patent/WO2019178006A2/en
Publication of JP2021517813A publication Critical patent/JP2021517813A/ja
Publication of JPWO2019178006A5 publication Critical patent/JPWO2019178006A5/ja
Publication of JP2021517813A5 publication Critical patent/JP2021517813A5/ja
Priority to JP2024188260A priority Critical patent/JP2025020210A/ja
Application granted granted Critical
Publication of JP7595827B2 publication Critical patent/JP7595827B2/ja
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JP2020548778A 2018-03-12 2019-03-11 免疫応答を改変するための生体分子の細胞内送達 Active JP7595827B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024188260A JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862641987P 2018-03-12 2018-03-12
US62/641,987 2018-03-12
US201862738941P 2018-09-28 2018-09-28
US62/738,941 2018-09-28
US201962794516P 2019-01-18 2019-01-18
US62/794,516 2019-01-18
PCT/US2019/021705 WO2019178006A2 (en) 2018-03-12 2019-03-11 Intracellular delivery of biomolecules to modify immune response

Related Child Applications (1)

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JP2024188260A Division JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

Publications (4)

Publication Number Publication Date
JP2021517813A JP2021517813A (ja) 2021-07-29
JPWO2019178006A5 JPWO2019178006A5 (https=) 2022-03-18
JP2021517813A5 true JP2021517813A5 (https=) 2022-03-18
JP7595827B2 JP7595827B2 (ja) 2024-12-09

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ID=66102189

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JP2020548778A Active JP7595827B2 (ja) 2018-03-12 2019-03-11 免疫応答を改変するための生体分子の細胞内送達
JP2024188260A Pending JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

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JP2024188260A Pending JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

Country Status (17)

Country Link
US (1) US20240374654A2 (https=)
EP (1) EP3765068A2 (https=)
JP (2) JP7595827B2 (https=)
KR (1) KR20200130835A (https=)
CN (1) CN112135627A (https=)
AU (2) AU2019234550B2 (https=)
BR (1) BR112020018612A2 (https=)
CA (1) CA3093828A1 (https=)
CO (1) CO2020012584A2 (https=)
CR (1) CR20200460A (https=)
IL (1) IL277188B2 (https=)
MA (1) MA52010A (https=)
MX (1) MX2020009439A (https=)
PH (1) PH12020551436A1 (https=)
SG (1) SG11202008864VA (https=)
TW (1) TW202003019A (https=)
WO (1) WO2019178006A2 (https=)

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EP3344575B1 (en) 2015-09-04 2020-04-15 SQZ Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
JP7602702B2 (ja) 2016-05-03 2024-12-19 ステムセル テクノロジーズ カナダ インコーポレーテッド 寛容性を誘導するための生体分子の細胞内送達
US12599656B2 (en) 2018-03-12 2026-04-14 Stemcell Technologies Canada Inc. Methods for treating HPV-associated diseases
WO2020014543A2 (en) 2018-07-11 2020-01-16 Actym Therapeutics, Inc. Engineered immunostimulatory bacterial strains and uses thereof
JP6884450B2 (ja) * 2019-02-14 2021-06-09 学校法人獨協学園獨協医科大学 T細胞ワクチン
CA3131701A1 (en) 2019-02-28 2020-09-03 Sqz Biotechnologies Company Delivery of biomolecules to pbmcs to modify an immune response
US11679388B2 (en) 2019-04-08 2023-06-20 Sqz Biotechnologies Company Cartridge for use in a system for delivery of a payload into a cell
AU2021272340A1 (en) 2020-05-11 2022-12-08 F. Hoffmann-La Roche Ag Combination therapy with modified pbmcs and an immunoconjugate
EP4188425B1 (en) 2020-07-29 2025-05-14 Stemcell Technologies Canada Inc. Methods to stimulate immune responses to mutant ras using anucleate cells
WO2022026620A1 (en) 2020-07-29 2022-02-03 Sqz Biotechnologies Company Methods to stimulate immune responses to mutant ras using nucleated cells
TW202241466A (zh) 2020-12-29 2022-11-01 美商Sqz生物科技公司 以經修飾pbmc治療癌症之方法
JP2024503279A (ja) 2020-12-29 2024-01-25 スクイーズ バイオテクノロジーズ カンパニー Pbmcの凍結保存のための製剤
US20220233676A1 (en) * 2020-12-29 2022-07-28 Sqz Biotechnologies Company Formulations of activating antigen carriers
US20220296691A1 (en) 2020-12-29 2022-09-22 Sqz Biotechnologies Company Methods for treating cancer with activating antigen carriers
CN115252772A (zh) * 2021-04-30 2022-11-01 华普生物技术(江苏)股份有限公司 人工合成的含CpG单链脱氧寡核苷酸在疫苗中的应用
WO2023010090A1 (en) 2021-07-29 2023-02-02 Sqz Biotechnologies Company Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery
WO2023087009A1 (en) 2021-11-11 2023-05-19 Sqz Biotechnologies Company Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery
CA3262748A1 (en) 2022-07-28 2024-02-01 Stemcell Technologies Canada Inc. IMPROVED ANTIGEN-PRESENTING CELL FORMULATIONS
CA3262756A1 (en) 2022-07-28 2024-02-01 Stemcell Technologies Canada Inc. CANCER TREATMENT METHODS WITH ENHANCED ANTIGEN-PRESENTING CELLS

Family Cites Families (10)

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JP2007528838A (ja) * 2003-12-24 2007-10-18 ライデン ユニバーシティ メディカル センター 腫瘍特異的ワクチンとしての合成タンパク質
ES2482192T3 (es) * 2007-05-31 2014-08-01 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Vacunación intradérmica del péptido de HPV
WO2009039125A1 (en) * 2007-09-17 2009-03-26 The Schepens Eye Research Institute, Inc. Use of ocular neuropeptides as immune adjuvants
MX2011012147A (es) 2009-05-15 2012-06-19 Irx Therapeutics Inc Inmunoterapia de vacuna.
CN107058101B (zh) * 2011-10-17 2021-06-01 麻省理工学院 细胞内传递
US20170212116A1 (en) * 2014-01-31 2017-07-27 Ulisse Biomed Srl Biosensors for the detection of infection and associated maladies
JP7523203B2 (ja) * 2014-10-31 2024-07-26 マサチューセッツ インスティテュート オブ テクノロジー 生体分子の免疫細胞への送達
ES2930017T3 (es) 2015-09-04 2022-12-05 Sqz Biotechnologies Co Suministro intracelular de biomoléculas mediado por una superficie con poros
CN108779475A (zh) * 2016-01-12 2018-11-09 Sqz生物技术公司 复合物的细胞内递送
US12599656B2 (en) * 2018-03-12 2026-04-14 Stemcell Technologies Canada Inc. Methods for treating HPV-associated diseases

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