KR20200130835A - 면역 반응을 조절하기 위한 생체분자의 세포내 전달 - Google Patents

면역 반응을 조절하기 위한 생체분자의 세포내 전달 Download PDF

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KR20200130835A
KR20200130835A KR1020207028580A KR20207028580A KR20200130835A KR 20200130835 A KR20200130835 A KR 20200130835A KR 1020207028580 A KR1020207028580 A KR 1020207028580A KR 20207028580 A KR20207028580 A KR 20207028580A KR 20200130835 A KR20200130835 A KR 20200130835A
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cells
modified
cell
antigen
adjuvant
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Inventor
스콧 러프헤드
리안 탈라리코
알폰소 비센트-수아레즈
매트 부티
하워드 번스타인
카타리나 블라고비크
아몬 알. 샤레이
켈란 흘라바티
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에스큐지 바이오테크놀로지스 컴퍼니
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KR1020207028580A 2018-03-12 2019-03-11 면역 반응을 조절하기 위한 생체분자의 세포내 전달 Ceased KR20200130835A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862641987P 2018-03-12 2018-03-12
US62/641,987 2018-03-12
US201862738941P 2018-09-28 2018-09-28
US62/738,941 2018-09-28
US201962794516P 2019-01-18 2019-01-18
US62/794,516 2019-01-18
PCT/US2019/021705 WO2019178006A2 (en) 2018-03-12 2019-03-11 Intracellular delivery of biomolecules to modify immune response

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US (1) US20240374654A2 (https=)
EP (1) EP3765068A2 (https=)
JP (2) JP7595827B2 (https=)
KR (1) KR20200130835A (https=)
CN (1) CN112135627A (https=)
AU (2) AU2019234550B2 (https=)
BR (1) BR112020018612A2 (https=)
CA (1) CA3093828A1 (https=)
CO (1) CO2020012584A2 (https=)
CR (1) CR20200460A (https=)
IL (1) IL277188B2 (https=)
MA (1) MA52010A (https=)
MX (1) MX2020009439A (https=)
PH (1) PH12020551436A1 (https=)
SG (1) SG11202008864VA (https=)
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JP6884450B2 (ja) * 2019-02-14 2021-06-09 学校法人獨協学園獨協医科大学 T細胞ワクチン
CA3131701A1 (en) 2019-02-28 2020-09-03 Sqz Biotechnologies Company Delivery of biomolecules to pbmcs to modify an immune response
US11679388B2 (en) 2019-04-08 2023-06-20 Sqz Biotechnologies Company Cartridge for use in a system for delivery of a payload into a cell
AU2021272340A1 (en) 2020-05-11 2022-12-08 F. Hoffmann-La Roche Ag Combination therapy with modified pbmcs and an immunoconjugate
EP4188425B1 (en) 2020-07-29 2025-05-14 Stemcell Technologies Canada Inc. Methods to stimulate immune responses to mutant ras using anucleate cells
WO2022026620A1 (en) 2020-07-29 2022-02-03 Sqz Biotechnologies Company Methods to stimulate immune responses to mutant ras using nucleated cells
TW202241466A (zh) 2020-12-29 2022-11-01 美商Sqz生物科技公司 以經修飾pbmc治療癌症之方法
JP2024503279A (ja) 2020-12-29 2024-01-25 スクイーズ バイオテクノロジーズ カンパニー Pbmcの凍結保存のための製剤
US20220233676A1 (en) * 2020-12-29 2022-07-28 Sqz Biotechnologies Company Formulations of activating antigen carriers
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CN115252772A (zh) * 2021-04-30 2022-11-01 华普生物技术(江苏)股份有限公司 人工合成的含CpG单链脱氧寡核苷酸在疫苗中的应用
WO2023010090A1 (en) 2021-07-29 2023-02-02 Sqz Biotechnologies Company Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery
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