JPWO2020145228A5 - - Google Patents

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Publication number
JPWO2020145228A5
JPWO2020145228A5 JP2020565733A JP2020565733A JPWO2020145228A5 JP WO2020145228 A5 JPWO2020145228 A5 JP WO2020145228A5 JP 2020565733 A JP2020565733 A JP 2020565733A JP 2020565733 A JP2020565733 A JP 2020565733A JP WO2020145228 A5 JPWO2020145228 A5 JP WO2020145228A5
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JP
Japan
Prior art keywords
lys
fab
gly
met
phenylene
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Pending
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JP2020565733A
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English (en)
Japanese (ja)
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JPWO2020145228A1 (ja
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Priority claimed from PCT/JP2020/000037 external-priority patent/WO2020145228A1/ja
Publication of JPWO2020145228A1 publication Critical patent/JPWO2020145228A1/ja
Publication of JPWO2020145228A5 publication Critical patent/JPWO2020145228A5/ja
Pending legal-status Critical Current

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JP2020565733A 2019-01-07 2020-01-06 配位子及びＣＥＡＣＡＭ５抗体Ｆａｂフラグメントからなる複合体 Pending JPWO2020145228A1 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2019000530 2019-01-07
JP2019000530 2019-01-07
JP2019206560 2019-11-14
JP2019206560 2019-11-14
PCT/JP2020/000037 WO2020145228A1 (ja) 2019-01-07 2020-01-06 配位子及びＣＥＡＣＡＭ５抗体Ｆａｂフラグメントからなる複合体

Publications (2)

Publication Number Publication Date
JPWO2020145228A1 JPWO2020145228A1 (ja) 2021-11-11
JPWO2020145228A5 true JPWO2020145228A5 (https=) 2022-10-24

Family

ID=71520276

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020565733A Pending JPWO2020145228A1 (ja) 2019-01-07 2020-01-06 配位子及びＣＥＡＣＡＭ５抗体Ｆａｂフラグメントからなる複合体
JP2020565732A Active JP7414370B2 (ja) 2019-01-07 2020-01-06 配位子、スペーサー、ペプチドリンカーおよび生物分子からなる複合体

Family Applications After (1)

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JP2020565732A Active JP7414370B2 (ja) 2019-01-07 2020-01-06 配位子、スペーサー、ペプチドリンカーおよび生物分子からなる複合体

Country Status (17)

Country Link
US (2) US20220096653A1 (https=)
EP (2) EP3909608A4 (https=)
JP (2) JPWO2020145228A1 (https=)
KR (2) KR20210113202A (https=)
CN (2) CN113301920B (https=)
AU (2) AU2020207081A1 (https=)
BR (2) BR112021013266A2 (https=)
CA (2) CA3125750A1 (https=)
CO (2) CO2021010116A2 (https=)
IL (2) IL284623B2 (https=)
JO (2) JOP20210183A1 (https=)
MX (2) MX2021008229A (https=)
PH (2) PH12021551631A1 (https=)
SG (2) SG11202107400QA (https=)
TW (2) TWI850308B (https=)
WO (2) WO2020145227A1 (https=)
ZA (2) ZA202105151B (https=)

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Publication number Priority date Publication date Assignee Title
TWI780082B (zh) 2016-11-18 2022-10-11 日商安斯泰來製藥股份有限公司 新穎抗人類ＭＵＣ１抗體Ｆａｂ片段
TWI795415B (zh) 2017-07-07 2023-03-11 日商安斯泰來製藥股份有限公司 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段
MX2020012351A (es) * 2018-05-17 2021-01-29 Astellas Pharma Inc Complejo que tiene fragmento fab de anticuerpo anti-muc1 de humano, enlazador peptido y/o ligando.
CA3115747A1 (en) 2018-10-10 2020-04-16 Astellas Pharma Inc. Pharmaceutical composition containing tagged site-antihuman antibody fab fragment complex
CA3174082A1 (en) 2020-03-04 2021-09-10 Nihon Medi-Physics Co., Ltd. Compound and radioactive labeling compound
KR20230154183A (ko) 2021-03-04 2023-11-07 니혼 메디피직스 가부시키가이샤 화합물 및 방사성 표지 화합물
CN118852044A (zh) * 2021-09-03 2024-10-29 晶核生物医药科技(南京)有限公司 一种肽脲素衍生物、含其的药物组合物及其应用
EP4536278A2 (en) * 2022-06-07 2025-04-16 Actinium Pharmaceuticals, Inc. Bifunctional chelators and conjugates
CA3265394A1 (en) * 2022-08-22 2024-02-29 Abdera Therapeutics Inc. VHH ANTIBODY CONJUGATES
WO2024235134A1 (zh) * 2023-05-12 2024-11-21 四川科伦博泰生物医药股份有限公司 具有靶向作用的偶联物及其制备方法和用途
WO2024243315A2 (en) * 2023-05-22 2024-11-28 Actinium Pharmaceuticals, Inc. Multi-arm bifunctional chelators
WO2025232116A1 (zh) * 2024-05-10 2025-11-13 四川科伦博泰生物医药股份有限公司 具有靶向作用的偶联物及其制备方法和用途
US12600794B2 (en) 2024-07-23 2026-04-14 Abdera Therapeutics Inc. 5T4 binding polypeptides and uses thereof

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
WO2005086875A2 (en) * 2004-03-11 2005-09-22 City Of Hope A humanized anti-cea t84.66 antibody and uses thereof
EP2083868A2 (en) 2006-10-04 2009-08-05 Københavns Universitet Generation of a cancer-specific immune response toward muc1 and cancer specific muc1 antibodies
JP5773352B2 (ja) 2008-10-28 2015-09-02 塩野義製薬株式会社 抗ｍｕｃ１抗体
CA2803520C (en) * 2009-07-08 2019-10-22 Lantheus Medical Imaging, Inc. N-alkoxyamide conjugates as imaging agents
CN102666567B (zh) * 2009-12-04 2015-08-26 免疫医疗公司 用于蛋白质、肽和其它分子的改进的f-18标记的方法和组合物
EP2471557A1 (en) * 2010-12-27 2012-07-04 Università degli Studi di Genova A conjugate of human albumin and 2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid useful for the localization of radionuclides for diagnostic and therapeutic purposes
KR102056932B1 (ko) * 2011-10-10 2019-12-17 시티 오브 호프 메디토프와 메디토프-결합 항체 및 이들의 용도
WO2013081091A1 (ja) 2011-12-01 2013-06-06 国立大学法人 千葉大学 非特異的腎集積が低減された放射性標識ポリペプチド作製用薬剤
MX379256B (es) * 2013-03-15 2025-03-10 Regeneron Pharma Moleculas biologicamente activas, conjugados de las mismas, y usos terapeuticos.
CN117138060A (zh) * 2014-10-07 2023-12-01 免疫医疗公司 抗体-药物缀合物的新辅助剂用途
CA2968990A1 (en) * 2015-01-09 2016-07-14 Immunomedics, Inc. Radiosensitivity of fluorophores and use of radioprotective agents for dual-modality imaging
WO2017150549A1 (ja) 2016-03-01 2017-09-08 国立大学法人 千葉大学 放射性標識薬剤
TWI780082B (zh) 2016-11-18 2022-10-11 日商安斯泰來製藥股份有限公司 新穎抗人類ＭＵＣ１抗體Ｆａｂ片段
US10758632B2 (en) * 2017-02-06 2020-09-01 City Of Hope NIR-conjugated tumor-specific antibodies and uses thereof
JP7207740B2 (ja) 2017-09-26 2023-01-18 国立大学法人千葉大学 放射性薬剤

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