SG11202107400QA - Conjugate comprising ligand and ceacam5 antibody fab fragment - Google Patents
Conjugate comprising ligand and ceacam5 antibody fab fragmentInfo
- Publication number
- SG11202107400QA SG11202107400QA SG11202107400QA SG11202107400QA SG11202107400QA SG 11202107400Q A SG11202107400Q A SG 11202107400QA SG 11202107400Q A SG11202107400Q A SG 11202107400QA SG 11202107400Q A SG11202107400Q A SG 11202107400QA SG 11202107400Q A SG11202107400Q A SG 11202107400QA
- Authority
- SG
- Singapore
- Prior art keywords
- conjugate
- ligand
- fab fragment
- antibody fab
- ceacam5 antibody
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
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- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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- Biochemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Radiology & Medical Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019000530 | 2019-01-07 | ||
| JP2019206560 | 2019-11-14 | ||
| PCT/JP2020/000037 WO2020145228A1 (ja) | 2019-01-07 | 2020-01-06 | 配位子及びCEACAM5抗体Fabフラグメントからなる複合体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202107400QA true SG11202107400QA (en) | 2021-08-30 |
Family
ID=71520276
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202107400QA SG11202107400QA (en) | 2019-01-07 | 2020-01-06 | Conjugate comprising ligand and ceacam5 antibody fab fragment |
| SG11202107398QA SG11202107398QA (en) | 2019-01-07 | 2020-01-06 | Conjugate comprising ligand, spacer, peptide linker, and biomolecule |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202107398QA SG11202107398QA (en) | 2019-01-07 | 2020-01-06 | Conjugate comprising ligand, spacer, peptide linker, and biomolecule |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20220096653A1 (https=) |
| EP (2) | EP3909608A4 (https=) |
| JP (2) | JPWO2020145228A1 (https=) |
| KR (2) | KR20210113202A (https=) |
| CN (2) | CN113301920B (https=) |
| AU (2) | AU2020207081A1 (https=) |
| BR (2) | BR112021013266A2 (https=) |
| CA (2) | CA3125750A1 (https=) |
| CO (2) | CO2021010116A2 (https=) |
| IL (2) | IL284623B2 (https=) |
| JO (2) | JOP20210183A1 (https=) |
| MX (2) | MX2021008229A (https=) |
| PH (2) | PH12021551631A1 (https=) |
| SG (2) | SG11202107400QA (https=) |
| TW (2) | TWI850308B (https=) |
| WO (2) | WO2020145227A1 (https=) |
| ZA (2) | ZA202105151B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI780082B (zh) | 2016-11-18 | 2022-10-11 | 日商安斯泰來製藥股份有限公司 | 新穎抗人類MUC1抗體Fab片段 |
| TWI795415B (zh) | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類CEACAM5抗體Fab片段 |
| MX2020012351A (es) * | 2018-05-17 | 2021-01-29 | Astellas Pharma Inc | Complejo que tiene fragmento fab de anticuerpo anti-muc1 de humano, enlazador peptido y/o ligando. |
| CA3115747A1 (en) | 2018-10-10 | 2020-04-16 | Astellas Pharma Inc. | Pharmaceutical composition containing tagged site-antihuman antibody fab fragment complex |
| CA3174082A1 (en) | 2020-03-04 | 2021-09-10 | Nihon Medi-Physics Co., Ltd. | Compound and radioactive labeling compound |
| KR20230154183A (ko) | 2021-03-04 | 2023-11-07 | 니혼 메디피직스 가부시키가이샤 | 화합물 및 방사성 표지 화합물 |
| CN118852044A (zh) * | 2021-09-03 | 2024-10-29 | 晶核生物医药科技(南京)有限公司 | 一种肽脲素衍生物、含其的药物组合物及其应用 |
| EP4536278A2 (en) * | 2022-06-07 | 2025-04-16 | Actinium Pharmaceuticals, Inc. | Bifunctional chelators and conjugates |
| CA3265394A1 (en) * | 2022-08-22 | 2024-02-29 | Abdera Therapeutics Inc. | VHH ANTIBODY CONJUGATES |
| WO2024235134A1 (zh) * | 2023-05-12 | 2024-11-21 | 四川科伦博泰生物医药股份有限公司 | 具有靶向作用的偶联物及其制备方法和用途 |
| WO2024243315A2 (en) * | 2023-05-22 | 2024-11-28 | Actinium Pharmaceuticals, Inc. | Multi-arm bifunctional chelators |
| WO2025232116A1 (zh) * | 2024-05-10 | 2025-11-13 | 四川科伦博泰生物医药股份有限公司 | 具有靶向作用的偶联物及其制备方法和用途 |
| US12600794B2 (en) | 2024-07-23 | 2026-04-14 | Abdera Therapeutics Inc. | 5T4 binding polypeptides and uses thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| WO2005086875A2 (en) * | 2004-03-11 | 2005-09-22 | City Of Hope | A humanized anti-cea t84.66 antibody and uses thereof |
| EP2083868A2 (en) | 2006-10-04 | 2009-08-05 | Københavns Universitet | Generation of a cancer-specific immune response toward muc1 and cancer specific muc1 antibodies |
| JP5773352B2 (ja) | 2008-10-28 | 2015-09-02 | 塩野義製薬株式会社 | 抗muc1抗体 |
| CA2803520C (en) * | 2009-07-08 | 2019-10-22 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| CN102666567B (zh) * | 2009-12-04 | 2015-08-26 | 免疫医疗公司 | 用于蛋白质、肽和其它分子的改进的f-18标记的方法和组合物 |
| EP2471557A1 (en) * | 2010-12-27 | 2012-07-04 | Università degli Studi di Genova | A conjugate of human albumin and 2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid useful for the localization of radionuclides for diagnostic and therapeutic purposes |
| KR102056932B1 (ko) * | 2011-10-10 | 2019-12-17 | 시티 오브 호프 | 메디토프와 메디토프-결합 항체 및 이들의 용도 |
| WO2013081091A1 (ja) | 2011-12-01 | 2013-06-06 | 国立大学法人 千葉大学 | 非特異的腎集積が低減された放射性標識ポリペプチド作製用薬剤 |
| MX379256B (es) * | 2013-03-15 | 2025-03-10 | Regeneron Pharma | Moleculas biologicamente activas, conjugados de las mismas, y usos terapeuticos. |
| CN117138060A (zh) * | 2014-10-07 | 2023-12-01 | 免疫医疗公司 | 抗体-药物缀合物的新辅助剂用途 |
| CA2968990A1 (en) * | 2015-01-09 | 2016-07-14 | Immunomedics, Inc. | Radiosensitivity of fluorophores and use of radioprotective agents for dual-modality imaging |
| WO2017150549A1 (ja) | 2016-03-01 | 2017-09-08 | 国立大学法人 千葉大学 | 放射性標識薬剤 |
| TWI780082B (zh) | 2016-11-18 | 2022-10-11 | 日商安斯泰來製藥股份有限公司 | 新穎抗人類MUC1抗體Fab片段 |
| US10758632B2 (en) * | 2017-02-06 | 2020-09-01 | City Of Hope | NIR-conjugated tumor-specific antibodies and uses thereof |
| JP7207740B2 (ja) | 2017-09-26 | 2023-01-18 | 国立大学法人千葉大学 | 放射性薬剤 |
-
2020
- 2020-01-06 JP JP2020565733A patent/JPWO2020145228A1/ja active Pending
- 2020-01-06 EP EP20738124.5A patent/EP3909608A4/en active Pending
- 2020-01-06 BR BR112021013266-0A patent/BR112021013266A2/pt unknown
- 2020-01-06 MX MX2021008229A patent/MX2021008229A/es unknown
- 2020-01-06 TW TW109100315A patent/TWI850308B/zh active
- 2020-01-06 CA CA3125750A patent/CA3125750A1/en active Pending
- 2020-01-06 PH PH1/2021/551631A patent/PH12021551631A1/en unknown
- 2020-01-06 EP EP20737956.1A patent/EP3909606A4/en not_active Withdrawn
- 2020-01-06 IL IL284623A patent/IL284623B2/en unknown
- 2020-01-06 CN CN202080007994.3A patent/CN113301920B/zh active Active
- 2020-01-06 BR BR112021013361-5A patent/BR112021013361A2/pt not_active IP Right Cessation
- 2020-01-06 TW TW109100275A patent/TW202043288A/zh unknown
- 2020-01-06 CA CA3125745A patent/CA3125745A1/en active Pending
- 2020-01-06 KR KR1020217020761A patent/KR20210113202A/ko active Pending
- 2020-01-06 WO PCT/JP2020/000036 patent/WO2020145227A1/ja not_active Ceased
- 2020-01-06 US US17/420,691 patent/US20220096653A1/en not_active Abandoned
- 2020-01-06 KR KR1020217020760A patent/KR20210113201A/ko not_active Withdrawn
- 2020-01-06 PH PH1/2021/551627A patent/PH12021551627A1/en unknown
- 2020-01-06 SG SG11202107400QA patent/SG11202107400QA/en unknown
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- 2020-01-06 JP JP2020565732A patent/JP7414370B2/ja active Active
- 2020-01-06 AU AU2020207081A patent/AU2020207081A1/en not_active Abandoned
- 2020-01-06 SG SG11202107398QA patent/SG11202107398QA/en unknown
- 2020-01-06 AU AU2020205851A patent/AU2020205851B2/en active Active
- 2020-01-06 WO PCT/JP2020/000037 patent/WO2020145228A1/ja not_active Ceased
- 2020-01-06 MX MX2021008230A patent/MX2021008230A/es unknown
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2021
- 2021-07-05 IL IL284622A patent/IL284622A/en unknown
- 2021-07-07 JO JOP/2021/0183A patent/JOP20210183A1/ar unknown
- 2021-07-07 JO JOP/2021/0180A patent/JOP20210180A1/ar unknown
- 2021-07-21 ZA ZA2021/05151A patent/ZA202105151B/en unknown
- 2021-07-21 ZA ZA2021/05150A patent/ZA202105150B/en unknown
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- 2021-07-30 CO CONC2021/0010115A patent/CO2021010115A2/es unknown
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