JPWO2020014588A5 - - Google Patents
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- Publication number
- JPWO2020014588A5 JPWO2020014588A5 JP2021523576A JP2021523576A JPWO2020014588A5 JP WO2020014588 A5 JPWO2020014588 A5 JP WO2020014588A5 JP 2021523576 A JP2021523576 A JP 2021523576A JP 2021523576 A JP2021523576 A JP 2021523576A JP WO2020014588 A5 JPWO2020014588 A5 JP WO2020014588A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acids
- g3bp1
- δrbd
- g3bp2
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101000893689 Homo sapiens Ras GTPase-activating protein-binding protein 1 Proteins 0.000 description 4
- 102100040854 Ras GTPase-activating protein-binding protein 1 Human genes 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 4
- 101000893674 Homo sapiens Ras GTPase-activating protein-binding protein 2 Proteins 0.000 description 2
- 102100040857 Ras GTPase-activating protein-binding protein 2 Human genes 0.000 description 2
- 102000014914 Carrier Proteins Human genes 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 108091008324 binding proteins Proteins 0.000 description 1
- 239000000539 dimer Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862697691P | 2018-07-13 | 2018-07-13 | |
| US62/697,691 | 2018-07-13 | ||
| US201862719751P | 2018-08-20 | 2018-08-20 | |
| US62/719,751 | 2018-08-20 | ||
| PCT/US2019/041564 WO2020014588A1 (en) | 2018-07-13 | 2019-07-12 | System and method for modulating stress granule assembly |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021531038A JP2021531038A (ja) | 2021-11-18 |
| JPWO2020014588A5 true JPWO2020014588A5 (https=) | 2022-12-06 |
| JP2021531038A5 JP2021531038A5 (https=) | 2022-12-06 |
Family
ID=69142650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523576A Pending JP2021531038A (ja) | 2018-07-13 | 2019-07-12 | ストレス顆粒集合を調節するためのシステム及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12195768B2 (https=) |
| EP (1) | EP3820494A4 (https=) |
| JP (1) | JP2021531038A (https=) |
| CN (1) | CN112423781A (https=) |
| WO (1) | WO2020014588A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3820494A4 (en) | 2018-07-13 | 2022-07-13 | The Trustees of Princeton University | System and method for modulating stress granule assembly |
| CN113135987B (zh) * | 2021-06-10 | 2022-07-12 | 浙江师范大学 | 一类来源于Caprin1的活性肽及其应用 |
| CN113214361B (zh) * | 2021-06-10 | 2022-06-10 | 浙江师范大学 | 一类包含fgdf基序的应激颗粒抑制剂及其应用 |
| WO2023174838A1 (en) * | 2022-03-14 | 2023-09-21 | F. Hoffmann-La Roche Ag | Modulators of the g3bp2-tau interaction for the treatment of tau associated diseases |
| EP4269424A1 (en) * | 2022-04-25 | 2023-11-01 | Københavns Universitet | Novel antiviral compounds and use thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR721101A0 (en) | 2001-08-23 | 2001-09-13 | University Of Queensland, The | Nucleic acid and polypeptide linked to breast cancer |
| JPWO2007132555A1 (ja) * | 2006-05-11 | 2009-09-24 | 国立大学法人 東京大学 | 細胞膜透過性ペプチドと細胞内におけるその使用 |
| EP2804598B1 (en) * | 2012-01-17 | 2019-05-15 | Kyoto University | Prophylactic and therapeutic drug for amyotrophic lateral sclerosis and method of screening therefor |
| JP6340366B2 (ja) * | 2012-07-31 | 2018-06-06 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | 運動ニューロン疾患を診断および処置する方法 |
| GB201318954D0 (en) * | 2013-10-28 | 2013-12-11 | Cupid Peptide Company Ltd | Cell transport |
| JP2019500899A (ja) * | 2015-11-23 | 2019-01-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ＣＲＩＳＰＲ／Ｃａｓ９の核送達を通じた細胞ＲＮＡの追跡と操作 |
| US20190085034A1 (en) | 2016-03-16 | 2019-03-21 | Tarveda Therapeutics, Inc. | Antibody mimic conjugates and particles |
| US10668128B2 (en) * | 2017-02-15 | 2020-06-02 | University Of South Carolina | Targeting G3BP proteins to accelerate nerve regeneration |
| MX2019013835A (es) * | 2017-05-24 | 2020-07-14 | Orphazyme As | Inductores de proteinas de choque termico y trastornos frontotemporales. |
| US10526380B2 (en) * | 2017-10-26 | 2020-01-07 | St. Jude Children's Research Hospital | Fusion protein and nucleic acid molecule for light-dependent stress granule assembly |
| EP3820494A4 (en) | 2018-07-13 | 2022-07-13 | The Trustees of Princeton University | System and method for modulating stress granule assembly |
-
2019
- 2019-07-12 EP EP19833830.3A patent/EP3820494A4/en active Pending
- 2019-07-12 WO PCT/US2019/041564 patent/WO2020014588A1/en not_active Ceased
- 2019-07-12 CN CN201980046655.3A patent/CN112423781A/zh active Pending
- 2019-07-12 JP JP2021523576A patent/JP2021531038A/ja active Pending
- 2019-07-12 US US17/258,783 patent/US12195768B2/en active Active
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