JPWO2019175776A5 - - Google Patents

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Publication number
JPWO2019175776A5
JPWO2019175776A5 JP2020548916A JP2020548916A JPWO2019175776A5 JP WO2019175776 A5 JPWO2019175776 A5 JP WO2019175776A5 JP 2020548916 A JP2020548916 A JP 2020548916A JP 2020548916 A JP2020548916 A JP 2020548916A JP WO2019175776 A5 JPWO2019175776 A5 JP WO2019175776A5
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JP
Japan
Prior art keywords
cancer
compound
salt
pharmaceutical
mammal
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JP2020548916A
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English (en)
Japanese (ja)
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JP2021518335A (ja
JP7266942B2 (ja
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Priority claimed from PCT/IB2019/052009 external-priority patent/WO2019175776A1/fr
Publication of JP2021518335A publication Critical patent/JP2021518335A/ja
Publication of JPWO2019175776A5 publication Critical patent/JPWO2019175776A5/ja
Application granted granted Critical
Publication of JP7266942B2 publication Critical patent/JP7266942B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020548916A 2018-03-15 2019-03-12 Sting(インターフェロン遺伝子刺激因子)のシクロペンタン-ベースのモジュレーター Active JP7266942B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862643467P 2018-03-15 2018-03-15
US62/643,467 2018-03-15
US201862666204P 2018-05-03 2018-05-03
US62/666,204 2018-05-03
US201862742532P 2018-10-08 2018-10-08
US62/742,532 2018-10-08
US201962809990P 2019-02-25 2019-02-25
US62/809,990 2019-02-25
PCT/IB2019/052009 WO2019175776A1 (fr) 2018-03-15 2019-03-12 Modulateurs de sting (stimulateur des gènes de l'interféron) à base de cyclopentane

Publications (3)

Publication Number Publication Date
JP2021518335A JP2021518335A (ja) 2021-08-02
JPWO2019175776A5 true JPWO2019175776A5 (fr) 2022-03-16
JP7266942B2 JP7266942B2 (ja) 2023-05-01

Family

ID=66103038

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020548916A Active JP7266942B2 (ja) 2018-03-15 2019-03-12 Sting(インターフェロン遺伝子刺激因子)のシクロペンタン-ベースのモジュレーター

Country Status (24)

Country Link
US (4) US10538542B2 (fr)
EP (1) EP3765474B1 (fr)
JP (1) JP7266942B2 (fr)
KR (1) KR20200131878A (fr)
CN (1) CN111918871A (fr)
AU (1) AU2019234043A1 (fr)
BR (1) BR112020018593A2 (fr)
CA (1) CA3093631C (fr)
CL (1) CL2020002352A1 (fr)
CR (1) CR20200382A (fr)
DO (1) DOP2020000160A (fr)
EC (1) ECSP20057847A (fr)
ES (1) ES2923298T3 (fr)
IL (1) IL277278A (fr)
MA (1) MA52012A (fr)
MX (1) MX2020009587A (fr)
NI (1) NI202000058A (fr)
PE (1) PE20210412A1 (fr)
PH (1) PH12020551486A1 (fr)
RU (1) RU2020130048A (fr)
SG (1) SG11202008102VA (fr)
TW (1) TWI741268B (fr)
UY (1) UY38145A (fr)
WO (1) WO2019175776A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7098748B2 (ja) 2017-12-20 2022-07-11 インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール,ヴイ.ヴイ.アイ. Stingアダプタータンパク質を活性化するホスホン酸結合を有する2’3’環状ジヌクレオチド
AU2018392213B2 (en) 2017-12-20 2021-03-04 Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. 3'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
TWI833744B (zh) 2018-04-06 2024-03-01 捷克科學院有機化學與生物化學研究所 3'3'-環二核苷酸
TW202028179A (zh) 2018-10-08 2020-08-01 美商普萊恩醫療公司 胺基酸化合物及使用方法
JP2022550297A (ja) * 2019-09-25 2022-12-01 ファイザー・インク Sting(インターフェロン遺伝子刺激因子)のヘテロ多環式モジュレーター
KR20220167275A (ko) 2020-04-10 2022-12-20 오노 야꾸힝 고교 가부시키가이샤 암 치료 방법
US11964978B2 (en) * 2021-03-18 2024-04-23 Pfizer Inc. Modulators of STING (stimulator of interferon genes)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
ES2692226T3 (es) 2014-06-04 2018-11-30 Glaxosmithkline Intellectual Property Development Limited Dinucleótidos cíclicos como moduladores de STING
GB201501462D0 (en) 2015-01-29 2015-03-18 Glaxosmithkline Ip Dev Ltd Novel compounds

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