JPWO2019162702A5 - - Google Patents
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- JPWO2019162702A5 JPWO2019162702A5 JP2020544648A JP2020544648A JPWO2019162702A5 JP WO2019162702 A5 JPWO2019162702 A5 JP WO2019162702A5 JP 2020544648 A JP2020544648 A JP 2020544648A JP 2020544648 A JP2020544648 A JP 2020544648A JP WO2019162702 A5 JPWO2019162702 A5 JP WO2019162702A5
- Authority
- JP
- Japan
- Prior art keywords
- groups
- optionally substituted
- group
- phenyl
- triazinan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1850217-9 | 2018-02-26 | ||
| SE1850217 | 2018-02-26 | ||
| GB1810667.4 | 2018-06-28 | ||
| GBGB1810667.4A GB201810667D0 (en) | 2018-06-28 | 2018-06-28 | New compounds and uses |
| PCT/GB2019/050523 WO2019162702A1 (en) | 2018-02-26 | 2019-02-26 | Triazine derivatives for treating diseases relating to neurotrophins |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021514963A JP2021514963A (ja) | 2021-06-17 |
| JP2021514963A5 JP2021514963A5 (https=) | 2022-03-07 |
| JPWO2019162702A5 true JPWO2019162702A5 (https=) | 2022-03-07 |
| JP7350759B2 JP7350759B2 (ja) | 2023-09-26 |
Family
ID=65729389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544648A Active JP7350759B2 (ja) | 2018-02-26 | 2019-02-26 | ニューロトロフィンに関連する疾患を治療するためのトリアジン誘導体 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US11352332B2 (https=) |
| EP (1) | EP3759088B8 (https=) |
| JP (1) | JP7350759B2 (https=) |
| KR (1) | KR102782749B1 (https=) |
| CN (1) | CN111819172B (https=) |
| AU (1) | AU2019223333B2 (https=) |
| BR (1) | BR112020017341A2 (https=) |
| CA (1) | CA3090864A1 (https=) |
| CL (1) | CL2020002157A1 (https=) |
| DK (1) | DK3759088T3 (https=) |
| ES (1) | ES2941529T3 (https=) |
| FI (1) | FI3759088T3 (https=) |
| HR (1) | HRP20230290T1 (https=) |
| HU (1) | HUE061751T2 (https=) |
| IL (1) | IL276624B2 (https=) |
| LT (1) | LT3759088T (https=) |
| MA (1) | MA52415A (https=) |
| MX (1) | MX2020008816A (https=) |
| PL (1) | PL3759088T3 (https=) |
| PT (1) | PT3759088T (https=) |
| SG (1) | SG11202007136VA (https=) |
| SI (1) | SI3759088T1 (https=) |
| WO (1) | WO2019162702A1 (https=) |
| ZA (1) | ZA202004220B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102335292B1 (ko) * | 2017-06-08 | 2021-12-06 | 닛뽕소다 가부시키가이샤 | 기록 재료 및 화합물 |
| MA52415A (fr) | 2018-02-26 | 2021-01-06 | AlzeCure Pharma AB | Dérivés de triazine pour le traitement de maladies associées à des neurotrophines |
| GB201810668D0 (en) | 2018-06-28 | 2018-08-15 | Stiftelsen Alzecure | New compounds |
| GB201912404D0 (en) * | 2019-08-29 | 2019-10-16 | AlzeCure Pharma AB | New compounds |
| CN113831299B (zh) * | 2020-06-23 | 2023-12-01 | 沈阳中化农药化工研发有限公司 | 苯甲酸酯类化合物及其应用 |
| WO2021259224A1 (zh) * | 2020-06-23 | 2021-12-30 | 沈阳中化农药化工研发有限公司 | 三嗪苯甲酸酯类化合物及其应用 |
| CN113831298B (zh) * | 2020-06-23 | 2023-12-01 | 沈阳中化农药化工研发有限公司 | 光活性羧酸酯类化合物及其应用 |
| KR102770474B1 (ko) * | 2021-03-23 | 2025-02-21 | 한국과학기술연구원 | 신규한 화합물 및 이를 포함하는 퇴행성 뇌질환 예방 또는 치료용 조성물 |
| CN118216517B (zh) * | 2022-12-21 | 2025-06-24 | 沈阳中化农药化工研发有限公司 | 一种除草组合物及其应用 |
| WO2025232990A1 (en) | 2024-05-09 | 2025-11-13 | AlzeCure Pharma AB | Triazinone derivatives for use in the treatment of inflammation |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2246109A1 (de) | 1972-09-20 | 1974-03-28 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazinderivate, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2313721A1 (de) * | 1973-03-20 | 1974-10-03 | Bayer Ag | Neue 1-phenylsubstituierte 1,3,5triazine, verfahren zu ihrer herstellung, sowie ihre verwendung als arzneimittel |
| DE2413722C3 (de) * | 1974-03-21 | 1982-04-08 | Bayer Ag, 5090 Leverkusen | Neue 1-(4-Phenoxy-phenyl)-1,3,5-triazin-Derivate, ein Verfahren zu ihrer Herstellung sowie ihre Anwendung als Arzneimittel |
| DE2718799A1 (de) | 1977-04-27 | 1978-11-09 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazin- derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel und wachstumsfoerderer |
| CA1185974A (en) | 1981-12-03 | 1985-04-23 | Adolf Parg | 1,3,5-triazinones and their use for controlling undesirable plant growth |
| DE3314739A1 (de) | 1983-04-23 | 1984-10-25 | Bayer Ag, 5090 Leverkusen | 1-(4-(4-(fluoralkylmethylthio- oder -sulfinyl- oder -sulfonyl-)phenoxy) phenyl)-1,3,5-triazin-2,4,6(1h,3h,5h)-trione, verfahren zu ihrer herstellung und ihre verwendung als coccidiosemittel |
| DE3408768A1 (de) * | 1984-03-09 | 1985-09-12 | Bayer Ag, 5090 Leverkusen | Immunstimulierende mittel |
| DE3516632A1 (de) | 1985-05-09 | 1986-11-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 1,3,5-triazintrionen |
| DE3516631A1 (de) | 1985-05-09 | 1986-11-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 3-methyl-1,3,5-triazintrionen |
| DE3703105A1 (de) | 1987-02-03 | 1988-08-11 | Bayer Ag | Mittel gegen protozoen bei insekten |
| DE3810080A1 (de) | 1988-03-25 | 1989-10-05 | Bayer Ag | Trisubstituierte 1,3,5-triazin-2,4,6-trione |
| DE3814323A1 (de) | 1988-04-28 | 1989-11-09 | Hoechst Ag | Wasserloesliche zubereitungen von coccidiostatica |
| US4933341A (en) | 1988-10-08 | 1990-06-12 | Bayer Aktiengesellschaft | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa |
| DE4000624A1 (de) | 1990-01-11 | 1991-07-18 | Bayer Ag | Fungizide verwendung von trisubstituierten 1,3,5-triazin-2,4,6-trionen, neue trisubstituierte 1,3,5-triazin-2,4,6-trione und verfahren zu ihrer herstellung |
| DE4329096A1 (de) | 1993-08-30 | 1995-03-02 | Bayer Ag | Heterocyclylbenzoheterocyclen |
| US5519133A (en) | 1995-06-02 | 1996-05-21 | American Cyanamid Co. | 3-(3-aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents |
| US5726126A (en) | 1995-06-02 | 1998-03-10 | American Cyanamid Company | 1-(3-heterocyclyphenyl)-S-triazine-2,6,6-oxo or thiotrione herbicidal agents |
| CZ146296A3 (en) | 1995-06-02 | 1997-04-16 | American Cyanamid Co | 3-(3-aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotriones, process of their preparation and herbicidal agents |
| US5604180A (en) | 1995-06-02 | 1997-02-18 | Crews, Jr.; Alvin D. | 3-(3-aryloxyphenyl)-1 (substituted methyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents |
| US5679791A (en) | 1996-07-25 | 1997-10-21 | American Cyanamid Company | 1-(3-heterocyclylphenyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents |
| MXPA01003542A (es) | 1998-10-08 | 2002-09-18 | New Ace Res Company | Composiciones y metodos nuevos para la prevencion y tratamiento de enfermedad causada por protozoarios. |
| AU2198100A (en) | 1998-12-22 | 2000-07-12 | Bayer Corporation | Triazineone compounds for treating diseases due to sarcosystis, neospora and toxoplasma |
| DE19937500A1 (de) | 1999-08-09 | 2001-02-15 | Bayer Ag | Substituierte Heterocyclylbenzofurane |
| DE19958388A1 (de) | 1999-12-03 | 2001-06-07 | Bayer Ag | Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten |
| US6444615B1 (en) | 2000-04-18 | 2002-09-03 | Dow Agrosciences Llc | Herbicidal imidazolidinetrione and thioxo-imidazolidinediones |
| DE10034800A1 (de) | 2000-07-18 | 2002-01-31 | Bayer Ag | Substituierte Benzostickstoffheterocyclen |
| DE10040110A1 (de) | 2000-08-17 | 2002-02-28 | Bayer Ag | Verwendung von Triazintrion-Sulfoxiden zur Bekämpfung von Coccidiosen |
| DE10040174A1 (de) | 2000-08-17 | 2002-02-28 | Bayer Ag | Verwendung von Triazintrion-Sulfonen zur Bekämpfung von Coccidiosen |
| AU2002324586B2 (en) | 2001-08-02 | 2008-04-24 | Neurocrine Biosciences, Inc. | 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists |
| WO2003029199A1 (en) | 2001-09-28 | 2003-04-10 | Takeda Chemical Industries, Ltd. | Benzene derivatives, process for preparing the same and use thereof |
| US6861523B2 (en) | 2002-02-08 | 2005-03-01 | Torrey Pines Institute For Molecular Studies | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries |
| WO2003101980A1 (en) | 2002-05-30 | 2003-12-11 | Solvay Pharmaceuticals B.V. | 1,3,5-triazine derivatives as ligands for human adenosine-a3 receptors |
| US7241763B2 (en) | 2002-07-15 | 2007-07-10 | Janssen Pharmaceutica N.V. | 3-furanyl analogs of toxoflavine as kinase inhibitors |
| DE102006038292A1 (de) | 2006-08-16 | 2008-02-21 | Bayer Healthcare Ag | Transdermale Anwendung von Triazinen zur Bekämpfung von Coccidien-Infektionen |
| WO2008148008A1 (en) | 2007-05-23 | 2008-12-04 | Emory University | High throughput bioassay for identifying selective trka receptor agonists, and gambogic amide, a selective trka agonist with neuroprotective activity |
| US20120004310A1 (en) | 2010-05-28 | 2012-01-05 | Longo Frank M | Non-peptide bdnf neurotrophin mimetics |
| RU2015141934A (ru) | 2013-03-15 | 2017-04-20 | Фарматрофикс, Инк. | Непептидные миметики нейротрофина bdnf |
| MX2016008842A (es) | 2014-01-20 | 2016-11-08 | Hoffmann La Roche | Derivados de n-fenil-lactama capaces de estimular la neurogenesis y su uso en el tratamiento de trastornos neurologicos. |
| MX387871B (es) | 2014-12-10 | 2025-03-19 | Mars Inc | Metodos para modular los receptores del gusto. |
| JP2020502225A (ja) | 2016-12-21 | 2020-01-23 | アルゼキュア ファーマ アーべー | トリアジントリオン誘導体、ならびにニューロトロフィン受容体および受容体型チロシンキナーゼのモジュレーターとしてのその使用。 |
| MA52415A (fr) | 2018-02-26 | 2021-01-06 | AlzeCure Pharma AB | Dérivés de triazine pour le traitement de maladies associées à des neurotrophines |
| GB201810668D0 (en) | 2018-06-28 | 2018-08-15 | Stiftelsen Alzecure | New compounds |
| GB201810669D0 (en) | 2018-06-28 | 2018-08-15 | Stiftelsen Alzecure | New compounds |
| GB201912404D0 (en) | 2019-08-29 | 2019-10-16 | AlzeCure Pharma AB | New compounds |
-
2019
- 2019-02-26 MA MA052415A patent/MA52415A/fr unknown
- 2019-02-26 PT PT197104730T patent/PT3759088T/pt unknown
- 2019-02-26 ES ES19710473T patent/ES2941529T3/es active Active
- 2019-02-26 EP EP19710473.0A patent/EP3759088B8/en active Active
- 2019-02-26 BR BR112020017341-0A patent/BR112020017341A2/pt unknown
- 2019-02-26 CN CN201980014798.6A patent/CN111819172B/zh active Active
- 2019-02-26 DK DK19710473.0T patent/DK3759088T3/da active
- 2019-02-26 MX MX2020008816A patent/MX2020008816A/es unknown
- 2019-02-26 SG SG11202007136VA patent/SG11202007136VA/en unknown
- 2019-02-26 JP JP2020544648A patent/JP7350759B2/ja active Active
- 2019-02-26 CA CA3090864A patent/CA3090864A1/en active Pending
- 2019-02-26 US US16/975,437 patent/US11352332B2/en active Active
- 2019-02-26 LT LTEPPCT/GB2019/050523T patent/LT3759088T/lt unknown
- 2019-02-26 PL PL19710473.0T patent/PL3759088T3/pl unknown
- 2019-02-26 HR HRP20230290TT patent/HRP20230290T1/hr unknown
- 2019-02-26 HU HUE19710473A patent/HUE061751T2/hu unknown
- 2019-02-26 IL IL276624A patent/IL276624B2/en unknown
- 2019-02-26 KR KR1020207025764A patent/KR102782749B1/ko active Active
- 2019-02-26 SI SI201930505T patent/SI3759088T1/sl unknown
- 2019-02-26 FI FIEP19710473.0T patent/FI3759088T3/fi active
- 2019-02-26 WO PCT/GB2019/050523 patent/WO2019162702A1/en not_active Ceased
- 2019-02-26 AU AU2019223333A patent/AU2019223333B2/en active Active
-
2020
- 2020-07-09 ZA ZA2020/04220A patent/ZA202004220B/en unknown
- 2020-08-21 CL CL2020002157A patent/CL2020002157A1/es unknown
-
2022
- 2022-06-02 US US17/830,724 patent/US12209071B2/en active Active
-
2024
- 2024-12-10 US US18/974,921 patent/US20250214948A1/en active Pending
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