JP2020530446A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020530446A5 JP2020530446A5 JP2020505383A JP2020505383A JP2020530446A5 JP 2020530446 A5 JP2020530446 A5 JP 2020530446A5 JP 2020505383 A JP2020505383 A JP 2020505383A JP 2020505383 A JP2020505383 A JP 2020505383A JP 2020530446 A5 JP2020530446 A5 JP 2020530446A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- alkyl
- optionally substituted
- compound according
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022211691A JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
| JP2024223976A JP2025031810A (ja) | 2017-08-09 | 2024-12-19 | 化合物、組成物、及び、方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762543307P | 2017-08-09 | 2017-08-09 | |
| US62/543,307 | 2017-08-09 | ||
| US201762553728P | 2017-09-01 | 2017-09-01 | |
| US62/553,728 | 2017-09-01 | ||
| US201762608504P | 2017-12-20 | 2017-12-20 | |
| US62/608,504 | 2017-12-20 | ||
| PCT/US2018/045868 WO2019032743A1 (en) | 2017-08-09 | 2018-08-08 | COMPOUNDS, COMPOSITIONS AND METHODS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022211691A Division JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020530446A JP2020530446A (ja) | 2020-10-22 |
| JP2020530446A5 true JP2020530446A5 (https=) | 2021-09-16 |
Family
ID=65272557
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020505383A Withdrawn JP2020530446A (ja) | 2017-08-09 | 2018-08-08 | 化合物、組成物、及び、方法 |
| JP2022211691A Withdrawn JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
| JP2024223976A Pending JP2025031810A (ja) | 2017-08-09 | 2024-12-19 | 化合物、組成物、及び、方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022211691A Withdrawn JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
| JP2024223976A Pending JP2025031810A (ja) | 2017-08-09 | 2024-12-19 | 化合物、組成物、及び、方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US11236100B2 (https=) |
| EP (1) | EP3665156A4 (https=) |
| JP (3) | JP2020530446A (https=) |
| KR (2) | KR102757890B1 (https=) |
| CN (3) | CN118239937A (https=) |
| AU (3) | AU2018313850B2 (https=) |
| CA (1) | CA3071024A1 (https=) |
| CL (1) | CL2020000299A1 (https=) |
| CO (1) | CO2020001220A2 (https=) |
| CR (1) | CR20200054A (https=) |
| IL (2) | IL272089B2 (https=) |
| MA (1) | MA49858A (https=) |
| MX (2) | MX2020001352A (https=) |
| MY (1) | MY201438A (https=) |
| PE (1) | PE20200834A1 (https=) |
| PH (1) | PH12020550028B1 (https=) |
| SA (1) | SA520411222B1 (https=) |
| SG (1) | SG11202000532SA (https=) |
| TW (1) | TW201920115A (https=) |
| WO (1) | WO2019032743A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110730777A (zh) * | 2017-06-07 | 2020-01-24 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为atf4通路抑制剂的化学化合物 |
| CN118239937A (zh) | 2017-08-09 | 2024-06-25 | 戴纳立制药公司 | 化合物、组合物及方法 |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| KR20190043437A (ko) | 2017-10-18 | 2019-04-26 | 씨제이헬스케어 주식회사 | 단백질 키나제 억제제로서의 헤테로고리 화합물 |
| US11939320B2 (en) | 2017-11-02 | 2024-03-26 | Abbvie Inc. | Modulators of the integrated stress pathway |
| WO2019118785A2 (en) | 2017-12-13 | 2019-06-20 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| WO2019236710A1 (en) | 2018-06-05 | 2019-12-12 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| TWI877863B (zh) | 2018-10-11 | 2025-03-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| KR102195348B1 (ko) | 2018-11-15 | 2020-12-24 | 에이치케이이노엔 주식회사 | 단백질 키나제 억제제로서의 신규 화합물 및 이를 포함하는 약제학적 조성물 |
| US12091392B2 (en) | 2019-02-13 | 2024-09-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| MA54953A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| MX2021012904A (es) | 2019-04-23 | 2022-01-18 | Evotec Int Gmbh | Moduladores de la via de respuesta al estres integrada. |
| CA3137213A1 (en) | 2019-04-23 | 2020-10-29 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| MX2021013197A (es) * | 2019-04-30 | 2022-02-24 | Calico Life Sciences Llc | Cicloalquilos sustituidos como moduladores de la vía integrada del estrés. |
| JP2022536663A (ja) | 2019-06-12 | 2022-08-18 | プラクシス バイオテック エルエルシー | 統合的ストレス応答経路のモジュレーター |
| AU2021213289A1 (en) | 2020-01-28 | 2022-07-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| MX2022011143A (es) | 2020-03-11 | 2022-10-13 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| JP2023546224A (ja) | 2020-10-22 | 2023-11-01 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 統合ストレス応答経路のモジュレーター |
| MX2023004623A (es) | 2020-10-22 | 2023-05-12 | Evotec Int Gmbh | Moduladores de la via integrada de respuesta al estres. |
| US20230391763A1 (en) | 2020-10-22 | 2023-12-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| IL302440A (en) * | 2020-10-30 | 2023-06-01 | Calico Life Sciences Llc | Combined pressure pathway modulators |
| CN117580824A (zh) * | 2020-10-30 | 2024-02-20 | 卡里科生命科学有限责任公司 | 整合应激通路的调节剂 |
| CN116507608A (zh) * | 2020-11-20 | 2023-07-28 | 戴纳立制药公司 | 化合物、组合物和方法 |
| EP4251622A1 (en) * | 2020-11-25 | 2023-10-04 | F. Hoffmann-La Roche AG | Aromatic bridged ring amide derivatives for the treatment and prophylaxis of hepatitis b virus infection |
| CN116710427A (zh) | 2020-12-18 | 2023-09-05 | 戴纳立制药公司 | 化合物的固体形式 |
| EP4543843A1 (en) * | 2022-06-23 | 2025-04-30 | Denali Therapeutics Inc. | Process for preparing modulators of eukaryotic initiation factor 2b |
| WO2024109736A1 (zh) * | 2022-11-21 | 2024-05-30 | 深圳众格生物科技有限公司 | 一种化合物、包含其的药物组合物及其合成方法和用途 |
| WO2025019827A1 (en) * | 2023-07-20 | 2025-01-23 | Denali Therapeutics Inc. | Formulation, solid dosage form, and methods |
| WO2025230528A1 (en) * | 2024-05-01 | 2025-11-06 | Calico Life Sciences Llc | Methods of treating amyotrophic lateral sclerosis |
| WO2026004939A1 (ja) * | 2024-06-28 | 2026-01-02 | キッセイ薬品工業株式会社 | ジ置換ビシクロ［１．１．１］ペンタン化合物 |
Family Cites Families (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6429207B1 (en) | 1997-11-21 | 2002-08-06 | Nps Pharmaceuticals, Inc. | Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases |
| CA2315050C (en) | 1998-10-16 | 2009-02-03 | Suntory Limited | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof |
| AR024077A1 (es) | 1999-05-25 | 2002-09-04 | Smithkline Beecham Corp | Compuestos antibacterianos |
| US20010047100A1 (en) | 2000-04-26 | 2001-11-29 | Kjaersgaard Hans Joergen | Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives |
| CA2443108A1 (en) | 2001-04-03 | 2002-10-17 | Merck & Co. Inc. | N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| KR20070057914A (ko) | 2004-09-02 | 2007-06-07 | 버텍스 파마슈티칼스 인코포레이티드 | 이온 채널 조절인자로서 유용한 퀴나졸린 |
| MX2007014507A (es) | 2005-05-24 | 2008-02-07 | Astrazeneca Ab | Aminopiperidin quinolinas y sus analogos azaisostericos con actividad antibacteriana. |
| UA96283C2 (uk) | 2005-12-23 | 2011-10-25 | Зіланд Фарма А/С | Модифіковані міметики лізину |
| TW200825072A (en) | 2006-10-20 | 2008-06-16 | Arete Therapeutics Inc | Soluble epoxide hydrolase inhibitors |
| ATE520687T1 (de) | 2007-06-15 | 2011-09-15 | Actelion Pharmaceuticals Ltd | 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e |
| AU2009325902B2 (en) | 2008-12-12 | 2015-01-29 | Idorsia Pharmaceuticals Ltd | 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives |
| CA2763589A1 (en) | 2009-05-28 | 2010-12-02 | President And Fellows Of Harvard College | N,n'-diarylurea compounds and n,n'-diarylthiourea compounds as inhibitors of translation initiation |
| LT3141252T (lt) | 2009-06-17 | 2018-11-12 | Vertex Pharmaceuticals Inc. | Gripo virusų replikacijos inhibitoriai |
| AR084457A1 (es) | 2010-12-22 | 2013-05-15 | Lundbeck & Co As H | Derivados de biciclo[3,2,1]octilamida |
| CN103403002B (zh) | 2011-02-24 | 2016-06-22 | 内尔维阿诺医学科学有限公司 | 作为激酶抑制剂的噻唑基苯基-苯磺酰氨基衍生物 |
| SG193002A1 (en) | 2011-03-10 | 2013-09-30 | Daiichi Sankyo Co Ltd | Dispiropyrrolidine derivative |
| US9139534B2 (en) * | 2011-04-22 | 2015-09-22 | Signal Pharmaceuticals, Llc | Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith |
| JP2015512873A (ja) | 2012-02-14 | 2015-04-30 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | 殺線虫性のシス（ヘテロ）アリールシクロプロピルカルボキサミド誘導体 |
| MX2015004285A (es) | 2012-10-02 | 2015-08-06 | Sumitomo Dainippon Pharma Co Ltd | Derivado de imidazol. |
| US9447026B2 (en) | 2013-03-14 | 2016-09-20 | Kalyra Pharmaceuticals, Inc. | Bicyclic analgesic compounds |
| JP6806562B2 (ja) * | 2013-03-15 | 2021-01-06 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ｅＩＦ２α経路の調節因子 |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US20160318856A1 (en) | 2013-09-11 | 2016-11-03 | The Brigham And Women's Hospital, Inc. | Substituted Urea eIF2alpha Kinase Activators |
| CN110229142A (zh) * | 2014-04-04 | 2019-09-13 | 希洛斯医药品股份有限公司 | 细胞周期蛋白依赖性激酶7(cdk7)的抑制剂 |
| US10308609B2 (en) | 2014-09-17 | 2019-06-04 | Zeno Royalties & Milestones, LLC | Bicyclic compounds |
| JP6787892B2 (ja) * | 2014-11-20 | 2020-11-18 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | Ｉｒａｋインヒビターとしてのヘテロアリール化合物及びその使用 |
| EP3623371A1 (en) | 2014-12-16 | 2020-03-18 | Axovant Sciences GmbH | Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors |
| US10808007B2 (en) | 2015-02-25 | 2020-10-20 | William Marsh Rice University | Desacetoxytubulysin H and analogs thereof |
| GB201506894D0 (en) | 2015-04-23 | 2015-06-10 | Galapagos Nv | Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders |
| BR112017023764A2 (pt) | 2015-05-05 | 2018-07-31 | Bayer Pharma AG | derivados de ciclohexano substituído por amido |
| TW201718557A (zh) | 2015-10-08 | 2017-06-01 | 歌林達有限公司 | 經吡唑基取代之四氫吡喃基碸 |
| TW201808914A (zh) * | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TWI763668B (zh) * | 2016-05-05 | 2022-05-11 | 美商嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TW201808903A (zh) | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TW201808888A (zh) * | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| AU2017279027A1 (en) | 2016-06-08 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Chemical Compounds |
| CA3026982A1 (en) | 2016-06-08 | 2017-12-14 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds as atf4 pathway inhibitors |
| TWI749024B (zh) * | 2016-07-06 | 2021-12-11 | 美商艾克奎斯特有限責任公司 | 化合物及其於降低尿酸位準之用途 |
| JOP20190072A1 (ar) | 2016-10-13 | 2019-04-07 | Glaxosmithkline Ip Dev Ltd | مشتقات 1، 3 سيكلوبوتان ثنائي الاستبدال أو آزيتيدين كمثبطات للإنزيم المخلق للبروستاجلاندين d المكون للدم |
| KR20190087622A (ko) | 2016-12-08 | 2019-07-24 | 보드 오브 리전츠 더 유니버시티 오브 텍사스 시스템 | 질환 치료를 위한 이중 류신 지퍼 (dlk) 키나아제의 바이시클로[1.1.1]펜탄 억제제 |
| CN110730777A (zh) * | 2017-06-07 | 2020-01-24 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为atf4通路抑制剂的化学化合物 |
| WO2018225093A1 (en) | 2017-06-07 | 2018-12-13 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds as atf4 pathway inhibitors |
| US20210145771A1 (en) * | 2017-07-03 | 2021-05-20 | Glaxosmithkline Intellectual Property Development Limited | N-(3-(2-(4-chlorophenoxy)acetamido)bicyclo[1.1.1] pentan-1-yl)-2-cyclobutane-1- carboxamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases |
| CN110896634A (zh) | 2017-07-03 | 2020-03-20 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为atf4抑制剂用于治疗癌症和其它疾病的2-(4-氯苯氧基)-n-((1-(2-(4-氯苯氧基)乙炔氮杂环丁烷-3-基)甲基)乙酰胺衍生物和相关化合物 |
| CN118239937A (zh) | 2017-08-09 | 2024-06-25 | 戴纳立制药公司 | 化合物、组合物及方法 |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| WO2019054430A1 (ja) | 2017-09-14 | 2019-03-21 | 第一三共株式会社 | 芳香族複素環を有するアミド化合物 |
| UY37956A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| EP3704098B1 (en) | 2017-11-02 | 2024-01-24 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| UY37958A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| SG11202004009TA (en) | 2017-11-02 | 2020-05-28 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| EP3704125B1 (en) | 2017-11-02 | 2026-03-11 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| CA3080804A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| US11939320B2 (en) | 2017-11-02 | 2024-03-26 | Abbvie Inc. | Modulators of the integrated stress pathway |
| UY37957A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| EP3704096B1 (en) | 2017-11-02 | 2026-04-22 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| WO2019118785A2 (en) | 2017-12-13 | 2019-06-20 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| WO2019183589A1 (en) | 2018-03-23 | 2019-09-26 | Denali Therapeutics Inc. | Modulators of eukaryotic initiation factor 2 |
| WO2019193541A1 (en) | 2018-04-06 | 2019-10-10 | Glaxosmithkline Intellectual Property Development Limited | Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors |
| WO2019193540A1 (en) | 2018-04-06 | 2019-10-10 | Glaxosmithkline Intellectual Property Development Limited | Heteroaryl derivatives of formula (i) as atf4 inhibitors |
| JP2021529814A (ja) | 2018-07-09 | 2021-11-04 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | 化学化合物 |
| WO2020031107A1 (en) | 2018-08-08 | 2020-02-13 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds |
| TWI877863B (zh) | 2018-10-11 | 2025-03-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| MA54953A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| US12091392B2 (en) | 2019-02-13 | 2024-09-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| US20220177456A1 (en) | 2019-03-06 | 2022-06-09 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| MX2021013197A (es) | 2019-04-30 | 2022-02-24 | Calico Life Sciences Llc | Cicloalquilos sustituidos como moduladores de la vía integrada del estrés. |
| AR118836A1 (es) | 2019-04-30 | 2021-11-03 | Calico Life Sciences Llc | Moduladores de la vía de tensión integrada |
| CN116710427A (zh) | 2020-12-18 | 2023-09-05 | 戴纳立制药公司 | 化合物的固体形式 |
-
2018
- 2018-08-08 CN CN202410183135.XA patent/CN118239937A/zh active Pending
- 2018-08-08 CN CN201880055607.6A patent/CN111094233B/zh active Active
- 2018-08-08 MY MYPI2020000561A patent/MY201438A/en unknown
- 2018-08-08 PH PH1/2020/550028A patent/PH12020550028B1/en unknown
- 2018-08-08 CA CA3071024A patent/CA3071024A1/en active Pending
- 2018-08-08 KR KR1020207005952A patent/KR102757890B1/ko active Active
- 2018-08-08 US US16/637,718 patent/US11236100B2/en active Active
- 2018-08-08 CN CN202410187269.9A patent/CN118239938A/zh active Pending
- 2018-08-08 IL IL272089A patent/IL272089B2/en unknown
- 2018-08-08 AU AU2018313850A patent/AU2018313850B2/en active Active
- 2018-08-08 PE PE2020000174A patent/PE20200834A1/es unknown
- 2018-08-08 MA MA049858A patent/MA49858A/fr unknown
- 2018-08-08 EP EP18844666.0A patent/EP3665156A4/en active Pending
- 2018-08-08 JP JP2020505383A patent/JP2020530446A/ja not_active Withdrawn
- 2018-08-08 SG SG11202000532SA patent/SG11202000532SA/en unknown
- 2018-08-08 WO PCT/US2018/045868 patent/WO2019032743A1/en not_active Ceased
- 2018-08-08 KR KR1020257001611A patent/KR20250017299A/ko active Pending
- 2018-08-08 CR CR20200054A patent/CR20200054A/es unknown
- 2018-08-08 MX MX2020001352A patent/MX2020001352A/es unknown
- 2018-08-08 IL IL301709A patent/IL301709B2/en unknown
- 2018-08-09 TW TW107127864A patent/TW201920115A/zh unknown
-
2020
- 2020-01-31 MX MX2023003989A patent/MX2023003989A/es unknown
- 2020-02-02 SA SA520411222A patent/SA520411222B1/ar unknown
- 2020-02-03 CO CONC2020/0001220A patent/CO2020001220A2/es unknown
- 2020-02-03 CL CL2020000299A patent/CL2020000299A1/es unknown
-
2021
- 2021-11-19 US US17/531,039 patent/US11851440B2/en active Active
-
2022
- 2022-12-28 JP JP2022211691A patent/JP2023052166A/ja not_active Withdrawn
-
2023
- 2023-03-22 AU AU2023201775A patent/AU2023201775A1/en not_active Abandoned
-
2024
- 2024-12-19 JP JP2024223976A patent/JP2025031810A/ja active Pending
-
2025
- 2025-01-08 US US19/014,044 patent/US20250388595A1/en active Pending
- 2025-01-31 AU AU2025200658A patent/AU2025200658A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020530446A5 (https=) | ||
| TWI724079B (zh) | 可溶性鳥苷酸環化酶刺激劑 | |
| US20230121195A1 (en) | 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer | |
| JP2020532506A5 (https=) | ||
| JP5728487B2 (ja) | 三環式ヘテロ環化合物 | |
| US20100280082A1 (en) | Metabotropic Glutamate Receptor Oxadiazole Ligands and Their Use as Potentiators | |
| US11254663B2 (en) | Substituted bicyclic compounds as farnesoid X receptor modulators | |
| JP2017193592A5 (https=) | ||
| JP2021517893A5 (https=) | ||
| JP5602230B2 (ja) | スフィンゴシン−１−リン酸受容体アゴニスト | |
| JP2009525340A5 (https=) | ||
| JP2018529745A (ja) | Ｎｒｆ２レギュレーターとしてのビアリールピラゾール | |
| EP2863914A1 (en) | Pyrazolyl derivatives as syk inhibitors | |
| JP2012515789A (ja) | スフィンゴシン−１−リン酸アゴニストとしてのピラゾール−１，２，４−オキサジアゾール誘導体 | |
| JP2021535137A5 (https=) | ||
| JP2017523223A5 (https=) | ||
| JP2014525467A (ja) | Ｐｄｅ１０モジュレーター | |
| JP2020520925A5 (https=) | ||
| JP2001503408A (ja) | ＧＡＢＡ▲下Ａ▼α５受容体サブタイプに対するリガンドとしてのチエニルシクロヘキサノン誘導体 | |
| JP2024536039A5 (https=) | ||
| WO2015155566A1 (en) | Fused pyrazole compounds as cb1r antagonists and uses thereof | |
| EA047337B1 (ru) | Замещенные бициклические соединения в качестве модуляторов фарнезоидного х-рецептора | |
| TW202409010A (zh) | 人類呼吸道融合病毒及人類間質肺炎病毒之抑制劑 | |
| HK1255028B (en) | 4-amino-2-(1h-pyrazolo[3,4-b]pyridin-3-yl)-6-oxo-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidine derivatives and the respective (1h-indazol-3-yl) derivatives as cgmp modulators for treating cardiovascular diseases |