ATE520687T1 - 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e - Google Patents

3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e

Info

Publication number
ATE520687T1
ATE520687T1 AT08763320T AT08763320T ATE520687T1 AT E520687 T1 ATE520687 T1 AT E520687T1 AT 08763320 T AT08763320 T AT 08763320T AT 08763320 T AT08763320 T AT 08763320T AT E520687 T1 ATE520687 T1 AT E520687T1
Authority
AT
Austria
Prior art keywords
amino
tetrahydropyranderiva
ethyl
Prior art date
Application number
AT08763320T
Other languages
English (en)
Inventor
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Acklin Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE520687T1 publication Critical patent/ATE520687T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT08763320T 2007-06-15 2008-06-13 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e ATE520687T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2007052301 2007-06-15
PCT/IB2008/052333 WO2008152603A1 (en) 2007-06-15 2008-06-13 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives

Publications (1)

Publication Number Publication Date
ATE520687T1 true ATE520687T1 (de) 2011-09-15

Family

ID=39772866

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08763320T ATE520687T1 (de) 2007-06-15 2008-06-13 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e

Country Status (15)

Country Link
US (1) US8193179B2 (de)
EP (1) EP2167494B1 (de)
JP (1) JP5274553B2 (de)
KR (1) KR101538814B1 (de)
CN (1) CN101711243B (de)
AR (1) AR067008A1 (de)
AT (1) ATE520687T1 (de)
AU (1) AU2008263397B2 (de)
BR (1) BRPI0812942B1 (de)
CA (1) CA2689102C (de)
ES (1) ES2370123T3 (de)
MX (1) MX2009013254A (de)
PL (1) PL2167494T3 (de)
TW (1) TWI414290B (de)
WO (1) WO2008152603A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8349828B2 (en) 2008-02-20 2013-01-08 Actelion Pharmaceuticals Ltd. Azatricyclic antibiotic compounds
US8349829B2 (en) 2008-06-03 2013-01-08 Actelion Pharmaceuticals Ltd. [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials
PT2344495E (pt) 2008-10-07 2015-04-01 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
NZ593891A (en) * 2008-12-12 2013-05-31 Actelion Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
ES2578182T3 (es) 2011-05-31 2016-07-21 Actelion Pharmaceuticals Ltd. Procedimientos de preparación de intermediarios sintéticos que pueden usarse para la fabricación de antibióticos
EP2723737A1 (de) * 2011-06-27 2014-04-30 Kyorin Pharmaceutical Co., Ltd. Verbrückte bicyclische verbindungen zur behandlung von bakteriellen infektionen
CN106083787B (zh) * 2016-06-21 2018-05-04 济南川成医药科技开发有限公司 一种4-(2-氨乙基)四氢吡喃的合成方法
WO2018026877A1 (en) 2016-08-05 2018-02-08 Calitor Sciences, Llc Process for preparing substituted quinolin-4-ol compounds
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
MA49858A (fr) 2017-08-09 2021-04-28 Denali Therapeutics Inc Composés, compositions et procédés
DK3676297T3 (da) 2017-09-01 2023-08-14 Denali Therapeutics Inc Forbindelser, sammensætninger og fremgangsmåder
SG11202108552QA (en) 2019-02-13 2021-09-29 Denali Therapeutics Inc Compounds, compositions and methods
MA54959A (fr) 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
GB201904469D0 (en) 2019-03-29 2019-05-15 Givaudan Sa Cosmetic composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816618B1 (fr) 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
BR0315221A (pt) * 2002-10-10 2005-08-23 Morphochem Ag Komb Chemie Compostos com atividade antibacteriana
US20070270417A1 (en) * 2004-07-22 2007-11-22 Glaxo Group Limited Antibacterial Agents
DE102004041163A1 (de) * 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
CA2580621A1 (en) * 2004-09-24 2006-03-30 Actelion Pharmaceuticals Ltd New bicyclic antibiotics
JP5314244B2 (ja) 2004-10-27 2013-10-16 富山化学工業株式会社 新規な含窒素複素環化合物およびその塩
WO2006125974A1 (en) 2005-05-24 2006-11-30 Astrazeneca Ab Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
WO2007086016A1 (en) * 2006-01-26 2007-08-02 Actelion Pharmaceuticals Ltd Tetrahydropyrane antibiotics
CA2643962A1 (en) * 2006-03-10 2007-09-20 Actelion Pharmaceuticals Ltd Antibiotic compounds

Also Published As

Publication number Publication date
JP5274553B2 (ja) 2013-08-28
US8193179B2 (en) 2012-06-05
AU2008263397B2 (en) 2013-12-05
TW200906416A (en) 2009-02-16
CA2689102C (en) 2016-07-26
TWI414290B (zh) 2013-11-11
BRPI0812942A8 (pt) 2018-05-02
WO2008152603A1 (en) 2008-12-18
CA2689102A1 (en) 2008-12-18
US20100179135A1 (en) 2010-07-15
BRPI0812942B1 (pt) 2018-11-21
PL2167494T3 (pl) 2012-01-31
CN101711243A (zh) 2010-05-19
BRPI0812942A2 (pt) 2014-12-16
KR20100023031A (ko) 2010-03-03
EP2167494B1 (de) 2011-08-17
JP2010529983A (ja) 2010-09-02
AU2008263397A1 (en) 2008-12-18
ES2370123T3 (es) 2011-12-12
AR067008A1 (es) 2009-09-30
CN101711243B (zh) 2013-01-09
KR101538814B1 (ko) 2015-07-22
EP2167494A1 (de) 2010-03-31
RU2010101003A (ru) 2011-07-20
MX2009013254A (es) 2010-01-25

Similar Documents

Publication Publication Date Title
ATE520687T1 (de) 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e
EP2170350A4 (de) Substituierte imidazoheterocyclen
ATE542825T1 (de) Substituierte piperidino-dihydrothienopyrimidine
BRPI0821573A2 (pt) benzofuropirimidonas
ATE501136T1 (de) Imidazopyridinone
DE502007001207D1 (de) Elektrosaugkopf
DE602008002772D1 (de) Polyvinylpyrrolidonpulverzusammensetzungen
DE112008003636A5 (de) Mehrzuggruppierer
DE602008000749D1 (de) Buschschneider
DE602008000923D1 (de) Einzelwaferätzgerät
BRPI0814519A2 (pt) Organopolissiloxano
BRPI0811451A2 (pt) Exopolissacarídeo
BRPI0815547A2 (pt) Depsipeptídeos cícliocos
BRPI0812840A2 (pt) 2-imidazolinas
DE602008001234D1 (de) Bandmaterialzuführvorrichtung
AT505058A3 (de) Türschliesssystem
DE602008004695D1 (de) Katalysatorträgerwabe
BRPI0812994A2 (pt) Microbiocidas
DE602008005589D1 (de) Rliganden
DE602008001674D1 (de) Wimpernwickler
DE112008001216A5 (de) Magnetronplasmaanlage
DE502008001694D1 (de) Mitfahrhubwagen
DE112008003094A5 (de) Geomatte
DE112008003196A5 (de) Handpipettiergerät
DE602008000292D1 (de) Werkzeughaltepositioniervorrichtung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2167494

Country of ref document: EP