JPS6318960B2 - - Google Patents
Info
- Publication number
- JPS6318960B2 JPS6318960B2 JP56046124A JP4612481A JPS6318960B2 JP S6318960 B2 JPS6318960 B2 JP S6318960B2 JP 56046124 A JP56046124 A JP 56046124A JP 4612481 A JP4612481 A JP 4612481A JP S6318960 B2 JPS6318960 B2 JP S6318960B2
- Authority
- JP
- Japan
- Prior art keywords
- insulin
- chain
- sulfonate
- solution
- protein concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13439080A | 1980-03-27 | 1980-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56154443A JPS56154443A (en) | 1981-11-30 |
| JPS6318960B2 true JPS6318960B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1988-04-20 |
Family
ID=22463156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4612481A Granted JPS56154443A (en) | 1980-03-27 | 1981-03-27 | Manufacture of insulin |
Country Status (28)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4451396A (en) * | 1983-08-01 | 1984-05-29 | Eli Lilly And Company | Process for inhibiting undesired thiol reactions during cyanogen bromide cleavage of peptides |
| DE3501641A1 (de) * | 1985-01-19 | 1986-07-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen |
| US4835251A (en) * | 1986-06-23 | 1989-05-30 | Genetech, Inc. | Method of chain combination |
| GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| JP3406244B2 (ja) | 1999-04-30 | 2003-05-12 | 伊藤ハム株式会社 | 新規な融合蛋白質からの組み換えインスリンの製造方法 |
-
1981
- 1981-03-24 ZA ZA00811970A patent/ZA811970B/xx unknown
- 1981-03-24 YU YU00769/81A patent/YU76981A/xx unknown
- 1981-03-24 NZ NZ196610A patent/NZ196610A/en unknown
- 1981-03-24 RO RO103807A patent/RO81640B/ro unknown
- 1981-03-24 PH PH25409A patent/PH16153A/en unknown
- 1981-03-24 CA CA000373706A patent/CA1155109A/en not_active Expired
- 1981-03-24 PL PL1981230295A patent/PL128599B1/pl unknown
- 1981-03-24 EG EG159/81A patent/EG15248A/xx active
- 1981-03-25 IL IL62483A patent/IL62483A/xx not_active IP Right Cessation
- 1981-03-25 FI FI810918A patent/FI810918L/fi not_active Application Discontinuation
- 1981-03-25 PT PT72733A patent/PT72733B/pt unknown
- 1981-03-26 DE DE8181301306T patent/DE3160862D1/de not_active Expired
- 1981-03-26 ES ES500750A patent/ES500750A0/es active Granted
- 1981-03-26 DK DK136581A patent/DK149756C/da not_active IP Right Cessation
- 1981-03-26 NO NO811038A patent/NO151897C/no unknown
- 1981-03-26 HU HU81771A patent/HU185416B/hu not_active IP Right Cessation
- 1981-03-26 GR GR64491A patent/GR73619B/el unknown
- 1981-03-26 SU SU813269596A patent/SU1327790A3/ru active
- 1981-03-26 GB GB8109542A patent/GB2072680B/en not_active Expired
- 1981-03-26 KR KR1019810000990A patent/KR840000947B1/ko not_active Expired
- 1981-03-26 IE IE680/81A patent/IE51608B1/en not_active IP Right Cessation
- 1981-03-26 DD DD81228623A patent/DD157613A5/de unknown
- 1981-03-26 EP EP81301306A patent/EP0037256B1/en not_active Expired
- 1981-03-26 AT AT81301306T patent/ATE4638T1/de not_active IP Right Cessation
- 1981-03-27 CS CS812273A patent/CS236463B2/cs unknown
- 1981-03-27 AU AU68844/81A patent/AU540645B2/en not_active Ceased
- 1981-03-27 JP JP4612481A patent/JPS56154443A/ja active Granted
- 1981-03-27 AR AR284772A patent/AR227305A1/es active
Also Published As
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