KR840000947B1 - 인슐린의 제조방법 - Google Patents
인슐린의 제조방법 Download PDFInfo
- Publication number
- KR840000947B1 KR840000947B1 KR1019810000990A KR810000990A KR840000947B1 KR 840000947 B1 KR840000947 B1 KR 840000947B1 KR 1019810000990 A KR1019810000990 A KR 1019810000990A KR 810000990 A KR810000990 A KR 810000990A KR 840000947 B1 KR840000947 B1 KR 840000947B1
- Authority
- KR
- South Korea
- Prior art keywords
- insulin
- chain
- solution
- sulfonate
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13439080A | 1980-03-27 | 1980-03-27 | |
| US134390 | 1980-03-27 | ||
| US134,390 | 1980-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR830004855A KR830004855A (ko) | 1983-07-20 |
| KR840000947B1 true KR840000947B1 (ko) | 1984-07-01 |
Family
ID=22463156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019810000990A Expired KR840000947B1 (ko) | 1980-03-27 | 1981-03-26 | 인슐린의 제조방법 |
Country Status (28)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4451396A (en) * | 1983-08-01 | 1984-05-29 | Eli Lilly And Company | Process for inhibiting undesired thiol reactions during cyanogen bromide cleavage of peptides |
| DE3501641A1 (de) * | 1985-01-19 | 1986-07-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen |
| US4835251A (en) * | 1986-06-23 | 1989-05-30 | Genetech, Inc. | Method of chain combination |
| GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| JP3406244B2 (ja) * | 1999-04-30 | 2003-05-12 | 伊藤ハム株式会社 | 新規な融合蛋白質からの組み換えインスリンの製造方法 |
-
1981
- 1981-03-24 EG EG159/81A patent/EG15248A/xx active
- 1981-03-24 RO RO103807A patent/RO81640B/ro unknown
- 1981-03-24 PH PH25409A patent/PH16153A/en unknown
- 1981-03-24 PL PL1981230295A patent/PL128599B1/pl unknown
- 1981-03-24 YU YU00769/81A patent/YU76981A/xx unknown
- 1981-03-24 CA CA000373706A patent/CA1155109A/en not_active Expired
- 1981-03-24 NZ NZ196610A patent/NZ196610A/en unknown
- 1981-03-24 ZA ZA00811970A patent/ZA811970B/xx unknown
- 1981-03-25 FI FI810918A patent/FI810918L/fi not_active Application Discontinuation
- 1981-03-25 IL IL62483A patent/IL62483A/xx not_active IP Right Cessation
- 1981-03-25 PT PT72733A patent/PT72733B/pt unknown
- 1981-03-26 SU SU813269596A patent/SU1327790A3/ru active
- 1981-03-26 NO NO811038A patent/NO151897C/no unknown
- 1981-03-26 ES ES500750A patent/ES8207551A1/es not_active Expired
- 1981-03-26 KR KR1019810000990A patent/KR840000947B1/ko not_active Expired
- 1981-03-26 EP EP81301306A patent/EP0037256B1/en not_active Expired
- 1981-03-26 GR GR64491A patent/GR73619B/el unknown
- 1981-03-26 DD DD81228623A patent/DD157613A5/de unknown
- 1981-03-26 HU HU81771A patent/HU185416B/hu not_active IP Right Cessation
- 1981-03-26 DK DK136581A patent/DK149756C/da not_active IP Right Cessation
- 1981-03-26 IE IE680/81A patent/IE51608B1/en not_active IP Right Cessation
- 1981-03-26 GB GB8109542A patent/GB2072680B/en not_active Expired
- 1981-03-26 DE DE8181301306T patent/DE3160862D1/de not_active Expired
- 1981-03-26 AT AT81301306T patent/ATE4638T1/de not_active IP Right Cessation
- 1981-03-27 JP JP4612481A patent/JPS56154443A/ja active Granted
- 1981-03-27 AU AU68844/81A patent/AU540645B2/en not_active Ceased
- 1981-03-27 CS CS812273A patent/CS236463B2/cs unknown
- 1981-03-27 AR AR284772A patent/AR227305A1/es active
Also Published As
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| US4835254A (en) | Process for reducing methionine sulfoxide residues in peptides or proteins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19810326 |
|
| PG1501 | Laying open of application | ||
| PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19840605 |
|
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19840920 |
|
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 19841022 Patent event code: PR07011E01D |
|
| PR1002 | Payment of registration fee |
Payment date: 19841022 End annual number: 3 Start annual number: 1 |
|
| PR1001 | Payment of annual fee |
Payment date: 19870701 Start annual number: 4 End annual number: 4 |
|
| PR1001 | Payment of annual fee |
Payment date: 19880701 Start annual number: 5 End annual number: 5 |
|
| PR1001 | Payment of annual fee |
Payment date: 19890701 Start annual number: 6 End annual number: 6 |
|
| PR1001 | Payment of annual fee |
Payment date: 19900630 Start annual number: 7 End annual number: 7 |
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| PR1001 | Payment of annual fee |
Payment date: 19910701 Start annual number: 8 End annual number: 8 |
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| PR1001 | Payment of annual fee |
Payment date: 19920630 Start annual number: 9 End annual number: 9 |
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| PR1001 | Payment of annual fee |
Payment date: 19930628 Start annual number: 10 End annual number: 10 |
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| PR1001 | Payment of annual fee |
Payment date: 19940616 Start annual number: 11 End annual number: 11 |
|
| PR1001 | Payment of annual fee |
Payment date: 19950615 Start annual number: 12 End annual number: 12 |
|
| PC1801 | Expiration of term |