IE51608B1 - Process for producing an insulin - Google Patents
Process for producing an insulinInfo
- Publication number
- IE51608B1 IE51608B1 IE680/81A IE68081A IE51608B1 IE 51608 B1 IE51608 B1 IE 51608B1 IE 680/81 A IE680/81 A IE 680/81A IE 68081 A IE68081 A IE 68081A IE 51608 B1 IE51608 B1 IE 51608B1
- Authority
- IE
- Ireland
- Prior art keywords
- insulin
- chain
- sulfonate
- reducing agent
- mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13439080A | 1980-03-27 | 1980-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE810680L IE810680L (en) | 1981-09-27 |
| IE51608B1 true IE51608B1 (en) | 1987-01-21 |
Family
ID=22463156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE680/81A IE51608B1 (en) | 1980-03-27 | 1981-03-26 | Process for producing an insulin |
Country Status (28)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4451396A (en) * | 1983-08-01 | 1984-05-29 | Eli Lilly And Company | Process for inhibiting undesired thiol reactions during cyanogen bromide cleavage of peptides |
| DE3501641A1 (de) * | 1985-01-19 | 1986-07-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen |
| US4835251A (en) * | 1986-06-23 | 1989-05-30 | Genetech, Inc. | Method of chain combination |
| GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| JP3406244B2 (ja) | 1999-04-30 | 2003-05-12 | 伊藤ハム株式会社 | 新規な融合蛋白質からの組み換えインスリンの製造方法 |
-
1981
- 1981-03-24 ZA ZA00811970A patent/ZA811970B/xx unknown
- 1981-03-24 YU YU00769/81A patent/YU76981A/xx unknown
- 1981-03-24 NZ NZ196610A patent/NZ196610A/en unknown
- 1981-03-24 RO RO103807A patent/RO81640B/ro unknown
- 1981-03-24 PH PH25409A patent/PH16153A/en unknown
- 1981-03-24 CA CA000373706A patent/CA1155109A/en not_active Expired
- 1981-03-24 PL PL1981230295A patent/PL128599B1/pl unknown
- 1981-03-24 EG EG159/81A patent/EG15248A/xx active
- 1981-03-25 IL IL62483A patent/IL62483A/xx not_active IP Right Cessation
- 1981-03-25 FI FI810918A patent/FI810918L/fi not_active Application Discontinuation
- 1981-03-25 PT PT72733A patent/PT72733B/pt unknown
- 1981-03-26 DE DE8181301306T patent/DE3160862D1/de not_active Expired
- 1981-03-26 ES ES500750A patent/ES500750A0/es active Granted
- 1981-03-26 DK DK136581A patent/DK149756C/da not_active IP Right Cessation
- 1981-03-26 NO NO811038A patent/NO151897C/no unknown
- 1981-03-26 HU HU81771A patent/HU185416B/hu not_active IP Right Cessation
- 1981-03-26 GR GR64491A patent/GR73619B/el unknown
- 1981-03-26 SU SU813269596A patent/SU1327790A3/ru active
- 1981-03-26 GB GB8109542A patent/GB2072680B/en not_active Expired
- 1981-03-26 KR KR1019810000990A patent/KR840000947B1/ko not_active Expired
- 1981-03-26 IE IE680/81A patent/IE51608B1/en not_active IP Right Cessation
- 1981-03-26 DD DD81228623A patent/DD157613A5/de unknown
- 1981-03-26 EP EP81301306A patent/EP0037256B1/en not_active Expired
- 1981-03-26 AT AT81301306T patent/ATE4638T1/de not_active IP Right Cessation
- 1981-03-27 CS CS812273A patent/CS236463B2/cs unknown
- 1981-03-27 AU AU68844/81A patent/AU540645B2/en not_active Ceased
- 1981-03-27 JP JP4612481A patent/JPS56154443A/ja active Granted
- 1981-03-27 AR AR284772A patent/AR227305A1/es active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4421685A (en) | Process for producing an insulin | |
| Goldenberg et al. | Circular and circularly permuted forms of bovine pancreatic trypsin inhibitor | |
| US5352769A (en) | Enzymatic removal of a protein amino-terminal sequence | |
| US5631347A (en) | Reducing gelation of a fatty acid-acylated protein | |
| JP4312828B2 (ja) | ε−アミノ基の選択的アシル化 | |
| Camardella et al. | Haemoglobin of the Antarctic fish Pagothenia bernacchii: Amino acid sequence, oxygen equilibria and crystal structure of its carbonmonoxy derivative | |
| US5698669A (en) | Tri-arginine insulins | |
| Peterson et al. | The amino acid sequence of the insulin from a primitive vertebrate, the atlantic hagfish (Myxine glutinosa). | |
| AU8076398A (en) | Improved process for obtaining insulin precursors having correctly bonded cystine bridges | |
| US4430266A (en) | Process for producing an insulin precursor | |
| Tager et al. | Primary structures of the proinsulin connecting peptides of the rat and the horse | |
| Sugeno et al. | The amino acid sequence of Scenedesmus ferredoxin | |
| Fry et al. | Isolation and partial characterization of a chromophore-peptide fragment from pepsin digests of phytochrome | |
| CA1244366A (en) | Anti-diabetic compounds | |
| EP0037256B1 (en) | Process for producing an insulin | |
| McDermott et al. | The disulfide content of calf γ-crystallin | |
| EP0037255B1 (en) | Process for producing an insulin precursor | |
| CA1243972A (en) | Anti-diabetic compounds | |
| WO2002004481A2 (en) | Process to increase protein stability | |
| Rüegg et al. | Reduction of S-Sulpho Groups by Tributylphosphine: An Improved IVIethod for the Recombination of Insulin Chains | |
| McClelland et al. | The refolding of hen egg white riboflavin-binding protein: effect of protein disulphide isomerase on the reoxidation of the reduced protein | |
| US5153308A (en) | S-sulfonated calcitonin derivatives | |
| NO178861B (no) | Fremgangsmåte for fremstilling av en insulinforlöper | |
| Hua et al. | The interaction of the S-thiomethyl insulin A and B chains in solution | |
| Marti et al. | Hb Altdorf α2β2 135 (H13) Ala→ Pro: A new electrophoretically silent unstable haemoglobin variant from Switzerland |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |