JPS6116368B2 - - Google Patents

Info

Publication number
JPS6116368B2
JPS6116368B2 JP56003038A JP303881A JPS6116368B2 JP S6116368 B2 JPS6116368 B2 JP S6116368B2 JP 56003038 A JP56003038 A JP 56003038A JP 303881 A JP303881 A JP 303881A JP S6116368 B2 JPS6116368 B2 JP S6116368B2
Authority
JP
Japan
Prior art keywords
dipyridamole
acid
sustained release
lacquer
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56003038A
Other languages
English (en)
Japanese (ja)
Other versions
JPS56103111A (en
Inventor
Guruubaa Peetaa
Buritsukuru Rorufu
Bosuraa Geruharuto
Sutoritsukaa Heruberuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS56103111A publication Critical patent/JPS56103111A/ja
Publication of JPS6116368B2 publication Critical patent/JPS6116368B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP303881A 1980-01-12 1981-01-12 Sustained release medicine containing dipyridamole and its manufacture Granted JPS56103111A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803000979 DE3000979A1 (de) 1980-01-12 1980-01-12 Neue dipyridamol-retardformen und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
JPS56103111A JPS56103111A (en) 1981-08-18
JPS6116368B2 true JPS6116368B2 (OSRAM) 1986-04-30

Family

ID=6091926

Family Applications (1)

Application Number Title Priority Date Filing Date
JP303881A Granted JPS56103111A (en) 1980-01-12 1981-01-12 Sustained release medicine containing dipyridamole and its manufacture

Country Status (32)

Country Link
US (1) US4367217A (OSRAM)
EP (1) EP0032562B1 (OSRAM)
JP (1) JPS56103111A (OSRAM)
AR (1) AR221983A1 (OSRAM)
AT (1) ATE6585T1 (OSRAM)
AU (1) AU539618B2 (OSRAM)
CA (1) CA1148084A (OSRAM)
CS (1) CS232713B2 (OSRAM)
DD (1) DD156943A5 (OSRAM)
DE (2) DE3000979A1 (OSRAM)
DK (1) DK158539C (OSRAM)
ES (1) ES8207428A1 (OSRAM)
FI (1) FI78835C (OSRAM)
GB (1) GB2067073B (OSRAM)
GR (1) GR73102B (OSRAM)
HK (1) HK62184A (OSRAM)
HU (1) HU184366B (OSRAM)
IE (1) IE50807B1 (OSRAM)
IL (1) IL61887A (OSRAM)
IN (1) IN155158B (OSRAM)
KE (1) KE3402A (OSRAM)
MA (1) MA19040A1 (OSRAM)
MY (1) MY8500559A (OSRAM)
NO (1) NO157369C (OSRAM)
NZ (1) NZ195994A (OSRAM)
OA (1) OA06720A (OSRAM)
PH (1) PH17063A (OSRAM)
PL (1) PL129290B1 (OSRAM)
PT (1) PT72330B (OSRAM)
SG (1) SG28184G (OSRAM)
YU (1) YU42549B (OSRAM)
ZA (1) ZA811661B (OSRAM)

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CN105640909B (zh) 2014-11-14 2019-09-20 正大天晴药业集团股份有限公司 一种含有达比加群酯的药用组合物
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Also Published As

Publication number Publication date
SG28184G (en) 1985-02-15
MA19040A1 (fr) 1981-10-01
GR73102B (OSRAM) 1984-02-02
CS232713B2 (en) 1985-02-14
MY8500559A (en) 1985-12-31
ZA811661B (en) 1982-09-29
DK9481A (da) 1981-07-13
PH17063A (en) 1984-05-24
GB2067073A (en) 1981-07-22
NO810061L (no) 1981-07-13
IE810040L (en) 1981-07-12
ATE6585T1 (de) 1984-03-15
EP0032562A1 (de) 1981-07-29
FI78835C (fi) 1989-10-10
DK158539C (da) 1990-11-05
US4367217A (en) 1983-01-04
ES498393A0 (es) 1982-09-16
NO157369B (no) 1987-11-30
CS23281A2 (en) 1984-06-18
AU6615681A (en) 1981-07-16
PT72330A (de) 1981-02-01
IL61887A (en) 1984-09-30
FI78835B (fi) 1989-06-30
YU3981A (en) 1983-09-30
FI810058L (fi) 1981-07-13
DK158539B (da) 1990-06-05
PL229157A1 (OSRAM) 1981-09-18
AR221983A1 (es) 1981-03-31
DE3067058D1 (en) 1984-04-19
ES8207428A1 (es) 1982-09-16
DD156943A5 (de) 1982-10-06
DE3000979A1 (de) 1981-07-23
CA1148084A (en) 1983-06-14
PL129290B1 (en) 1984-04-30
NO157369C (no) 1988-03-16
PT72330B (de) 1982-07-23
AU539618B2 (en) 1984-10-11
KE3402A (en) 1984-06-08
JPS56103111A (en) 1981-08-18
HU184366B (en) 1984-08-28
HK62184A (en) 1984-08-17
IE50807B1 (en) 1986-07-23
NZ195994A (en) 1984-04-27
YU42549B (en) 1988-10-31
OA06720A (fr) 1982-06-30
GB2067073B (en) 1984-02-15
EP0032562B1 (de) 1984-03-14
IN155158B (OSRAM) 1985-01-05

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