JPS5951957B2 - Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法 - Google Patents

Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法

Info

Publication number
JPS5951957B2
JPS5951957B2 JP54169494A JP16949479A JPS5951957B2 JP S5951957 B2 JPS5951957 B2 JP S5951957B2 JP 54169494 A JP54169494 A JP 54169494A JP 16949479 A JP16949479 A JP 16949479A JP S5951957 B2 JPS5951957 B2 JP S5951957B2
Authority
JP
Japan
Prior art keywords
group
groups
formula
amino
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54169494A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55105691A (en
Inventor
リカルド・スカルタツツイ−ニ
ハンス・ビツケル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS55105691A publication Critical patent/JPS55105691A/ja
Publication of JPS5951957B2 publication Critical patent/JPS5951957B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP54169494A 1972-06-29 1979-12-27 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法 Expired JPS5951957B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH978872A CH587268A5 (en) 1972-06-29 1972-06-29 Substd carboxylic acid derivs - broad spectrum antibiotics and inters
CH9788/72-3--- 1972-06-29
CH12195/723--- 1972-08-17
CH18722/72---4 1972-12-22
CH2655/732---4 1973-02-23

Publications (2)

Publication Number Publication Date
JPS55105691A JPS55105691A (en) 1980-08-13
JPS5951957B2 true JPS5951957B2 (ja) 1984-12-17

Family

ID=4355646

Family Applications (9)

Application Number Title Priority Date Filing Date
JP54169494A Expired JPS5951957B2 (ja) 1972-06-29 1979-12-27 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP54169495A Expired JPS5938955B2 (ja) 1972-06-29 1979-12-27 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP54169493A Expired JPS5934196B2 (ja) 1972-06-29 1979-12-27 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP55094119A Expired JPS6019916B2 (ja) 1972-06-29 1980-07-11 ０−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP9928280A Granted JPS5668684A (en) 1972-06-29 1980-07-18 Manufacture of oosubstituted 7 betaaaminoo33 cephemm33oll44carboxylic acid compound
JP9928380A Granted JPS5649390A (en) 1972-06-29 1980-07-18 Manufacture of 1 oxide of 33cephem compound
JP56017382A Expired JPS597716B2 (ja) 1972-06-29 1981-02-07 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP58146771A Expired JPS6053037B2 (ja) 1972-06-29 1983-08-12 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製造方法
JP58146770A Expired JPS6054320B2 (ja) 1972-06-29 1983-08-12 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製造方法

Family Applications After (8)

Application Number Title Priority Date Filing Date
JP54169495A Expired JPS5938955B2 (ja) 1972-06-29 1979-12-27 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP54169493A Expired JPS5934196B2 (ja) 1972-06-29 1979-12-27 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP55094119A Expired JPS6019916B2 (ja) 1972-06-29 1980-07-11 ０−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP9928280A Granted JPS5668684A (en) 1972-06-29 1980-07-18 Manufacture of oosubstituted 7 betaaaminoo33 cephemm33oll44carboxylic acid compound
JP9928380A Granted JPS5649390A (en) 1972-06-29 1980-07-18 Manufacture of 1 oxide of 33cephem compound
JP56017382A Expired JPS597716B2 (ja) 1972-06-29 1981-02-07 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JP58146771A Expired JPS6053037B2 (ja) 1972-06-29 1983-08-12 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製造方法
JP58146770A Expired JPS6054320B2 (ja) 1972-06-29 1983-08-12 Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製造方法

Country Status (5)

Country Link
JP (9) JPS5951957B2 (Direct)
CH (1) CH587268A5 (Direct)
PL (1) PL104396B1 (Direct)
SU (2) SU542474A3 (Direct)
ZA (1) ZA734050B (Direct)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011128232A1 (de) 2010-04-13 2011-10-20 Wacker Chemie Ag Oberflächenbehandlung von zementären untergründen

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045435A (en) * 1974-10-09 1977-08-30 Eli Lilly And Company Preparation of cephalosporin ethers
JPH064638B2 (ja) * 1985-05-17 1994-01-19 大塚化学株式会社 β−ラクタム誘導体の製造方法
EP0280240B1 (en) * 1987-02-27 1994-09-14 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, process for their preparation and antibacterial agents
JPH0651816U (ja) * 1992-12-15 1994-07-15 株式会社ニコン 測量機のクランプ装置
WO2021008846A1 (de) 2019-07-12 2021-01-21 Alzchem Trostberg Gmbh Verfahren zur herstellung einer metastabilen kristallmodifikation von n-(aminoiminomethyl)-2-aminoethansäure (iv)
DE102019118898A1 (de) 2019-07-12 2021-01-14 Alzchem Trostberg Gmbh Konzentrat zur Herstellung einer Tränklösung
DE102019121526A1 (de) 2019-08-09 2021-02-11 Alzchem Trostberg Gmbh Konzentrat zur Herstellung von Tränklösungen (II)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3234223A (en) * 1962-02-16 1966-02-08 Ciba Geigy Corp Preparation of 7-amino-cephalosporanic acid and derivatives
GB1070312A (en) * 1962-11-23 1967-06-01 Glaxo Lab Ltd Preparation of 7-aminocephalosporanic acid
CH447172A (de) * 1963-03-15 1967-11-30 Ciba Geigy Verfahren zur Herstellung von 7-Amino-cephalosporansäure-estern
US3503964A (en) * 1966-11-29 1970-03-31 Ciba Geigy Corp Process for the manufacture of esters of 7-aminocephalosporanic acid
US3549628A (en) * 1967-07-07 1970-12-22 Lilly Co Eli Side chain cleavage in desacetoxycephalosporin esters
US3647786A (en) * 1968-10-03 1972-03-07 Lilly Co Eli Preparation of cephalosporin sulfoxides
US3641014A (en) * 1968-10-03 1972-02-08 Lilly Co Eli Reduction of delta**3-cephalosporin sulfoxides
US3641018A (en) * 1969-06-26 1972-02-08 Lilly Co Eli Process for preparing 7-amino cephalosporanic acid
GB1308822A (en) * 1970-04-14 1973-03-07 Beecham Group Ltd 4-isopropylidene-3-oxocephams
JPS5035079B1 (Direct) * 1970-10-17 1975-11-13

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011128232A1 (de) 2010-04-13 2011-10-20 Wacker Chemie Ag Oberflächenbehandlung von zementären untergründen

Also Published As

Publication number Publication date
JPS6053037B2 (ja) 1985-11-22
JPS5934196B2 (ja) 1984-08-21
SU542474A3 (ru) 1977-01-05
JPS618070B2 (Direct) 1986-03-11
JPS5938955B2 (ja) 1984-09-20
ZA734050B (en) 1974-05-29
JPS618071B2 (Direct) 1986-03-11
JPS55105691A (en) 1980-08-13
JPS5976090A (ja) 1984-04-28
JPS56127392A (en) 1981-10-06
JPS5976089A (ja) 1984-04-28
JPS6054320B2 (ja) 1985-11-29
SU609469A3 (ru) 1978-05-30
JPS5649390A (en) 1981-05-02
JPS5639093A (en) 1981-04-14
JPS597716B2 (ja) 1984-02-20
PL104396B1 (pl) 1979-08-31
CH587268A5 (en) 1977-04-29
JPS5668684A (en) 1981-06-09
JPS55105692A (en) 1980-08-13
JPS55105690A (en) 1980-08-13
JPS6019916B2 (ja) 1985-05-18

Similar Documents

Publication Publication Date Title
US3658799A (en) Cephalosporin compounds
JPS5933599B2 (ja) Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
US4319027A (en) Process for the manufacture of ceohem enol derivatives
US4147864A (en) Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
US4389524A (en) Cepham compounds
JPS5934714B2 (ja) ７β−アミノ−セフアム−３−オル−４−カルボン酸化合物または相当する３−θ−エステルの製法
DE2127287A1 (de) 8 Oxo 5 thia 1 azabicyclo eckige Klammer auf 4,2,0 eckige Klammer zu oct 2 en Verbindungen
JPS5951957B2 (ja) Ｏ−置換された７β−アミノ−３−セフエム−３−オ−ル−４−カルボン酸化合物の製法
JPS6124398B2 (Direct)
US4104469A (en) 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US4012380A (en) 7-Acylamino-3-acyl-2(or 3)cephems
US4550162A (en) Process for the manufacture of enol derivatives
US4255328A (en) Sulfide intermediates for the manufacture of enol derivatives
US4434287A (en) Cephalosporin derivatives
US4301278A (en) Process for the manufacture of enol derivatives
US3705160A (en) Thiazacyclic hydroxy compounds and process for their manufacture
JPH0246594B2 (Direct)
US4579684A (en) Process for the manufacture of enol derivatives
JPH0641003A (ja) カルボキシアルケンアミドセファロスポリン
JPS6124400B2 (Direct)
CH602635A5 (en) 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CS228101B2 (cs) Způsob výroby derivátů Z^-aminocefam-a-on-á-karboxylové kyseliny
CH605737A5 (en) 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
JPS60214772A (ja) ７β‐アミノ‐３（または‐２）‐セフエム‐３‐オール‐４‐カルボン酸化合物または２‐オキソアゼチジン化合物の製法
JPS59176292A (ja) ７−｛α−（２−アミノ−４−チアゾリル）−α−〔（２−アミノ−４−チアゾリル）メトキシイミノ〕アセトアミド｝−３−置換−３−セフエム−４−カルボン酸