JPS5846079A - ベンゾチアゾリン環を有するエ−テル類 - Google Patents

ベンゾチアゾリン環を有するエ−テル類

Info

Publication number
JPS5846079A
JPS5846079A JP56144148A JP14414881A JPS5846079A JP S5846079 A JPS5846079 A JP S5846079A JP 56144148 A JP56144148 A JP 56144148A JP 14414881 A JP14414881 A JP 14414881A JP S5846079 A JPS5846079 A JP S5846079A
Authority
JP
Japan
Prior art keywords
group
yield
kbr
benzothiazoline
acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56144148A
Other languages
English (en)
Japanese (ja)
Inventor
Junichi Iwao
岩尾　順一
Masayuki Ooya
大矢　正雪
Tadashi Iso
磯　正
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Priority to JP56144148A priority Critical patent/JPS5846079A/ja
Priority to IT23146/82A priority patent/IT1196423B/it
Priority to CH2716/83A priority patent/CH654001A5/de
Priority to DE823248957T priority patent/DE3248957T1/de
Priority to NL8220310A priority patent/NL8220310A/nl
Priority to AT0904882A priority patent/AT379592B/de
Priority to PCT/JP1982/000363 priority patent/WO1983000865A1/ja
Priority to US06/503,160 priority patent/US4479949A/en
Priority to GB08311096A priority patent/GB2115815B/en
Priority to AU89026/82A priority patent/AU541223B2/en
Priority to CA000411159A priority patent/CA1169860A/en
Priority to ES515655A priority patent/ES8308552A1/es
Priority to BE2/59831A priority patent/BE894358A/fr
Priority to FR8215454A priority patent/FR2512820B1/fr
Publication of JPS5846079A publication Critical patent/JPS5846079A/ja
Priority to SE8302352A priority patent/SE444681B/sv
Priority to FI831431A priority patent/FI68232C/fi
Priority to NO831653A priority patent/NO831653L/no
Priority to DK211283A priority patent/DK164403C/da
Priority to ES522386A priority patent/ES522386A0/es
Priority to US06/612,323 priority patent/US4558125A/en
Priority to US06/612,322 priority patent/US4552969A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP56144148A 1981-09-12 1981-09-12 ベンゾチアゾリン環を有するエ−テル類 Pending JPS5846079A (ja)

Priority Applications (21)

Application Number Priority Date Filing Date Title
JP56144148A JPS5846079A (ja) 1981-09-12 1981-09-12 ベンゾチアゾリン環を有するエ−テル類
IT23146/82A IT1196423B (it) 1981-09-12 1982-09-07 Benzotiazolin-composti
ES515655A ES8308552A1 (es) 1981-09-12 1982-09-10 Un procedimiento para la preparacion de derivados de benzotiazolina.
DE823248957T DE3248957T1 (de) 1981-09-12 1982-09-10 Benzothiazolinverbindungen
NL8220310A NL8220310A (nl) 1981-09-12 1982-09-10 Benzothiazolineverbindingen.
AT0904882A AT379592B (de) 1981-09-12 1982-09-10 Verfahren zur herstellung von neuen benzothiazolin-verbindungen und von deren salzen
PCT/JP1982/000363 WO1983000865A1 (fr) 1981-09-12 1982-09-10 Composes de benzothiazoline
US06/503,160 US4479949A (en) 1981-09-12 1982-09-10 Benzothiazoline compounds
GB08311096A GB2115815B (en) 1981-09-12 1982-09-10 Benzothiazoline compounds
AU89026/82A AU541223B2 (en) 1981-09-12 1982-09-10 Benzothiazoline compounds
CA000411159A CA1169860A (en) 1981-09-12 1982-09-10 Processes for preparing novel benzothiazoline derivatives
CH2716/83A CH654001A5 (de) 1981-09-12 1982-09-10 Benzothiazolin-verbindungen.
BE2/59831A BE894358A (fr) 1981-09-12 1982-09-10 Composes de benzothiazoline
FR8215454A FR2512820B1 (fr) 1981-09-12 1982-09-13 Nouveaux derives de benzothiazoline utiles comme medicaments et procede pour leur preparation
SE8302352A SE444681B (sv) 1981-09-12 1983-04-26 Nya bensotiazolinforeningar samt farmaceutisk komposition derav for behandling av kardiovaskulera sjukdomar
FI831431A FI68232C (fi) 1981-09-12 1983-04-27 Foerfarande foer framstaellning av benzotiazolinfoereningar me farmaceutiskt verkan
NO831653A NO831653L (no) 1981-09-12 1983-05-10 Fremgangsmaate ved fremstilling av nye terapeutisk virksomme benzothiazolinforbindelser
DK211283A DK164403C (da) 1981-09-12 1983-05-11 Analogifremgangsmaade til fremstilling af benzothiazolinderivater
ES522386A ES522386A0 (es) 1981-09-12 1983-05-13 Un procedimiento para la preparacion de derivados de benzotiazolina.
US06/612,323 US4558125A (en) 1981-09-12 1984-05-21 Benzothiazoline compounds which contain a carbonyl group useful for treating cardiovascular disease
US06/612,322 US4552969A (en) 1981-09-12 1984-05-21 3-Alkanoyl benzothiazoline compounds useful for treating cardiovascular disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56144148A JPS5846079A (ja) 1981-09-12 1981-09-12 ベンゾチアゾリン環を有するエ−テル類

Publications (1)

Publication Number Publication Date
JPS5846079A true JPS5846079A (ja) 1983-03-17

Family

ID=15355326

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56144148A Pending JPS5846079A (ja) 1981-09-12 1981-09-12 ベンゾチアゾリン環を有するエ−テル類

Country Status (18)

Country Link
US (3) US4479949A (enExample)
JP (1) JPS5846079A (enExample)
AT (1) AT379592B (enExample)
AU (1) AU541223B2 (enExample)
BE (1) BE894358A (enExample)
CA (1) CA1169860A (enExample)
CH (1) CH654001A5 (enExample)
DE (1) DE3248957T1 (enExample)
DK (1) DK164403C (enExample)
ES (2) ES8308552A1 (enExample)
FI (1) FI68232C (enExample)
FR (1) FR2512820B1 (enExample)
GB (1) GB2115815B (enExample)
IT (1) IT1196423B (enExample)
NL (1) NL8220310A (enExample)
NO (1) NO831653L (enExample)
SE (1) SE444681B (enExample)
WO (1) WO1983000865A1 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56164877A (en) * 1980-05-23 1981-12-18 Fujitsu Ltd Manufacture of head for thermal printer
JPS60139679A (ja) * 1983-12-27 1985-07-24 Santen Pharmaceut Co Ltd ２−アリ−ルベンゾチアゾリン誘導体
JPS60207396A (ja) * 1984-03-31 1985-10-18 ロ−ム株式会社 配線基板
JPS61110568A (ja) * 1984-10-31 1986-05-28 アルカテル・エヌ・ブイ プリンタ装置
JPS62221679A (ja) * 1986-03-19 1987-09-29 Santen Pharmaceut Co Ltd ベンゾチアゾリン誘導体
WO2003082840A1 (fr) 2002-03-29 2003-10-09 Santen Pharmaceutical Co., Ltd. Agoniste du récepteur k-opioïde comprenant un dérivé de 2-phénylbenzothiazoline

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5846079A (ja) * 1981-09-12 1983-03-17 Santen Pharmaceut Co Ltd ベンゾチアゾリン環を有するエ−テル類
DK143684A (da) * 1983-03-12 1984-09-13 Bayer Ag Anvendelse af pyrazolonderivater som lipoxygenasehaemmer ved terapi af isaer ischaemi og hjerterytmeforstyrrelser
US4728651A (en) * 1985-10-24 1988-03-01 Hoechst-Roussel Pharmaceuticals Inc. Antihypertensive thieno-isoxazoles and -pyrazoles
US5147881A (en) * 1990-11-14 1992-09-15 Pfizer Inc 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
CA2907921C (en) * 2013-03-22 2021-09-07 Ayumi Pharmaceutical Corporation Inhibition of il-2 production

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2996512A (en) * 1961-08-15 Therapeutic derivatives of aryl-
US3117124A (en) * 1957-03-20 1964-01-07 Olin Mathieson Benzothiazole, benzothiazine, and benzothiazepine compounds
FR1255312A (fr) * 1957-10-31 1961-03-10 Crookes Lab Ltd Dérivés des aryl-benzothiazoles et leur mode de préparation
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
BE754245A (fr) * 1969-08-01 1970-12-31 Sumitomo Chemical Co Derives d'acides phenoxy carboxyliques
US3574218A (en) * 1969-08-11 1971-04-06 Egyt Gyogyszervegyeszeti Gyar 2-aryl- or aralkyl-substituted benzazole derivatives
US3720683A (en) * 1970-09-02 1973-03-13 Squibb & Sons Inc 2-phenyl-3-acylbenzothiazolines and their oxides
JPS5371071A (en) * 1976-12-08 1978-06-24 Teijin Ltd Alpha-phenoxyacetic acid derivs.
JPS57179175A (en) * 1981-04-30 1982-11-04 Shinzo Kano Preparation of 2-benzothiazolinone derivative or salt thereof
JPS5846079A (ja) * 1981-09-12 1983-03-17 Santen Pharmaceut Co Ltd ベンゾチアゾリン環を有するエ−テル類

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56164877A (en) * 1980-05-23 1981-12-18 Fujitsu Ltd Manufacture of head for thermal printer
JPS60139679A (ja) * 1983-12-27 1985-07-24 Santen Pharmaceut Co Ltd ２−アリ−ルベンゾチアゾリン誘導体
JPS60207396A (ja) * 1984-03-31 1985-10-18 ロ−ム株式会社 配線基板
JPS61110568A (ja) * 1984-10-31 1986-05-28 アルカテル・エヌ・ブイ プリンタ装置
JPS62221679A (ja) * 1986-03-19 1987-09-29 Santen Pharmaceut Co Ltd ベンゾチアゾリン誘導体
WO2003082840A1 (fr) 2002-03-29 2003-10-09 Santen Pharmaceutical Co., Ltd. Agoniste du récepteur k-opioïde comprenant un dérivé de 2-phénylbenzothiazoline
US7112598B2 (en) 2002-03-29 2006-09-26 Santen Pharmaceutical Co., Ltd. κ opioid receptor agonist comprising 2-phenylbenzothiazoline derivative
US7410987B2 (en) 2002-03-29 2008-08-12 Santen Pharmaceutical Co., Ltd. Method for treating pain or pruritis by administering κ-opioid receptor agonist comprising 2-phenylbenzothiazoline derivative
EP2042173A2 (en) 2002-03-29 2009-04-01 Santen Pharmaceutical Co., Ltd. Kappa-opioid receptor agonist comprising 2-phenylbenzothiazoline derivative
JP2009143940A (ja) * 2002-03-29 2009-07-02 Santen Pharmaceut Co Ltd ２−フェニルベンゾチアゾリン誘導体またはその塩類からなるκオピオイド受容体アゴニスト

Also Published As

Publication number Publication date
ES8407033A1 (es) 1984-08-16
DK164403C (da) 1992-11-16
FI831431A0 (fi) 1983-04-27
GB2115815B (en) 1985-06-19
IT1196423B (it) 1988-11-16
SE444681B (sv) 1986-04-28
DK211283D0 (da) 1983-05-11
NL8220310A (nl) 1983-08-01
SE8302352D0 (sv) 1983-04-26
ES522386A0 (es) 1984-08-16
CH654001A5 (de) 1986-01-31
DE3248957C2 (enExample) 1989-09-21
US4479949A (en) 1984-10-30
SE8302352L (sv) 1983-04-26
FI68232C (fi) 1985-08-12
FR2512820A1 (fr) 1983-03-18
DE3248957T1 (de) 1983-10-20
WO1983000865A1 (fr) 1983-03-17
NO831653L (no) 1983-05-10
CA1169860A (en) 1984-06-26
FR2512820B1 (fr) 1986-11-21
US4558125A (en) 1985-12-10
GB8311096D0 (en) 1983-05-25
DK211283A (da) 1983-05-11
GB2115815A (en) 1983-09-14
AU541223B2 (en) 1984-12-20
DK164403B (da) 1992-06-22
IT8223146A0 (it) 1982-09-07
AT379592B (de) 1986-01-27
FI831431L (fi) 1983-04-27
ES515655A0 (es) 1983-09-16
BE894358A (fr) 1983-01-03
FI68232B (fi) 1985-04-30
US4552969A (en) 1985-11-12
AU8902682A (en) 1983-03-28
ES8308552A1 (es) 1983-09-16
ATA904882A (de) 1985-06-15

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