JPS58152822A - 新規なニトロメチル化剤 - Google Patents

新規なニトロメチル化剤

Info

Publication number
JPS58152822A
JPS58152822A JP58022231A JP2223183A JPS58152822A JP S58152822 A JPS58152822 A JP S58152822A JP 58022231 A JP58022231 A JP 58022231A JP 2223183 A JP2223183 A JP 2223183A JP S58152822 A JPS58152822 A JP S58152822A
Authority
JP
Japan
Prior art keywords
compound
group
following formula
agent
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58022231A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0480889B2 (fr
Inventor
デレク・ハロルド・リチヤ−ド・バ−トン
ウイリアム・ブランクス・マザウエル
サミ−ル・ザ−ル・ザ−ル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS58152822A publication Critical patent/JPS58152822A/ja
Publication of JPH0480889B2 publication Critical patent/JPH0480889B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP58022231A 1982-02-18 1983-02-15 新規なニトロメチル化剤 Granted JPS58152822A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8202681A FR2521567A1 (fr) 1982-02-18 1982-02-18 Nouveaux derives steroides 17(20)nitro, leur procede de preparation et leur application a la preparation de corticosteroides
FR8202681 1982-02-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3352924A Division JPH0559095A (ja) 1982-02-18 1991-12-17 新規なニトロメチレン化合物及びその誘導体の製造法

Publications (2)

Publication Number Publication Date
JPS58152822A true JPS58152822A (ja) 1983-09-10
JPH0480889B2 JPH0480889B2 (fr) 1992-12-21

Family

ID=9271110

Family Applications (2)

Application Number Title Priority Date Filing Date
JP58022231A Granted JPS58152822A (ja) 1982-02-18 1983-02-15 新規なニトロメチル化剤
JP3352924A Pending JPH0559095A (ja) 1982-02-18 1991-12-17 新規なニトロメチレン化合物及びその誘導体の製造法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3352924A Pending JPH0559095A (ja) 1982-02-18 1991-12-17 新規なニトロメチレン化合物及びその誘導体の製造法

Country Status (7)

Country Link
US (1) US4490296A (fr)
EP (2) EP0087359B1 (fr)
JP (2) JPS58152822A (fr)
AT (1) ATE46346T1 (fr)
DE (1) DE3379947D1 (fr)
FR (1) FR2521567A1 (fr)
HU (1) HU191199B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2033516T3 (es) * 1988-04-08 1993-03-16 Roussel-Uclaf Procedimiento para preparar 9 alfa-hidroxi-17 metileno-esteroides.
US5300523A (en) * 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
IT1282289B1 (it) * 1995-06-23 1998-03-16 Sigma Tau Ind Farmaceuti 17-idrossiimminoalchil e 17-idrossiimminometilalchenil ciclopentaperidrofenantreni attivi sul sistema cardiovascolare,
CN100345862C (zh) * 2004-03-12 2007-10-31 浙江医药股份有限公司新昌制药厂 甾类化合物的制备方法
CN104262442B (zh) * 2014-10-10 2016-01-20 湖南科瑞生物制药股份有限公司 黄体酮的制备方法
CN109796344B (zh) * 2018-12-20 2022-01-14 浙江工业大学 一种(e)-1,3-二苯基-4-硝基-1-丁烯的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4834850A (fr) * 1972-01-13 1973-05-22
JPS4916414A (fr) * 1972-05-20 1974-02-13

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2383603A (en) * 1945-08-28 Condensation of nitroalkanes with
US3980681A (en) * 1969-11-21 1976-09-14 Peter Job Sykes Process for the preparation of 11-β-nitro-oxysteroids
HU162303B (fr) * 1970-09-30 1973-01-29
FR2462445A1 (fr) * 1979-07-31 1981-02-13 Roussel Uclaf Nouveaux derives 17-/(hydroxymethyl) (formamido) methylene/steroides, leur procede de preparation et leur application a l'introduction de la chaine laterale hydroxyacetyle
FR2486947A1 (fr) * 1980-07-15 1982-01-22 Roussel Uclaf Nouveaux derives steroides 20-isonitriles 17(20) insatures, leur procede de preparation et leur application a la preparation des steroides 17a-hydroxy 20-ceto

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4834850A (fr) * 1972-01-13 1973-05-22
JPS4916414A (fr) * 1972-05-20 1974-02-13

Also Published As

Publication number Publication date
EP0087359A3 (en) 1984-08-22
JPH0559095A (ja) 1993-03-09
EP0192288A1 (fr) 1986-08-27
DE3379947D1 (en) 1989-07-06
FR2521567A1 (fr) 1983-08-19
EP0087359A2 (fr) 1983-08-31
HU191199B (en) 1987-01-28
FR2521567B1 (fr) 1984-05-04
ATE46346T1 (de) 1989-09-15
EP0087359B1 (fr) 1989-05-31
EP0192288B1 (fr) 1989-09-13
JPH0480889B2 (fr) 1992-12-21
US4490296A (en) 1984-12-25

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