JPS5628202A - Polysaccharide rbs substance, its preparation, and antitumor agent containing it as effective component - Google Patents
Polysaccharide rbs substance, its preparation, and antitumor agent containing it as effective componentInfo
- Publication number
- JPS5628202A JPS5628202A JP10221679A JP10221679A JPS5628202A JP S5628202 A JPS5628202 A JP S5628202A JP 10221679 A JP10221679 A JP 10221679A JP 10221679 A JP10221679 A JP 10221679A JP S5628202 A JPS5628202 A JP S5628202A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- sulfuric acid
- substance
- acid reaction
- antitumor agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54102216A JPS5943929B2 (ja) | 1979-08-13 | 1979-08-13 | 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤 |
US06/174,537 US4366308A (en) | 1979-08-13 | 1980-08-01 | Process for the production of polysaccharide RBS substance |
US06/174,536 US4357323A (en) | 1979-08-13 | 1980-08-01 | Polysaccharide RBS substance and antitumor agent containing same |
EP80104699A EP0025123B1 (en) | 1979-08-13 | 1980-08-09 | Polysaccharide rbs substance, process for the production thereof and antitumor agent containing it |
DE8080104699T DE3068681D1 (en) | 1979-08-13 | 1980-08-09 | Polysaccharide rbs substance, process for the production thereof and antitumor agent containing it |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54102216A JPS5943929B2 (ja) | 1979-08-13 | 1979-08-13 | 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5628202A true JPS5628202A (en) | 1981-03-19 |
JPS5943929B2 JPS5943929B2 (ja) | 1984-10-25 |
Family
ID=14321462
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54102216A Expired JPS5943929B2 (ja) | 1979-08-13 | 1979-08-13 | 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤 |
Country Status (4)
Country | Link |
---|---|
US (2) | US4357323A (ja) |
EP (1) | EP0025123B1 (ja) |
JP (1) | JPS5943929B2 (ja) |
DE (1) | DE3068681D1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05112455A (ja) * | 1991-06-17 | 1993-05-07 | Snow Brand Milk Prod Co Ltd | 大腸癌抑制物質 |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6153220A (ja) * | 1984-08-22 | 1986-03-17 | Sapporo Breweries Ltd | 新規多糖体ron物質,その製造法およびそれを有効成分とする抗腫瘍剤,免疫調節剤並びに感染症予防治療剤 |
DE3205074A1 (de) * | 1981-02-19 | 1982-12-16 | Toyama Chemical Co. Ltd., Tokyo | Neue carcinostatische und immunostimulierende substanzen, verfahren zur herstellung derselben und carcinostatische mittel mit einem gehalt derselben |
US4477437A (en) * | 1981-02-19 | 1984-10-16 | Toyama Chemical Co., Ltd. | Substances having carcinostatic and immunostimulating activity |
JPS58118519A (ja) * | 1981-12-29 | 1983-07-14 | Noda Shiyokukin Kogyo Kk | 抗がん剤 |
DE3305047A1 (de) * | 1982-02-19 | 1983-09-22 | Terumo Kabushiki Kaisha trading as Terumo Corp., Tokyo | Polysaccharide, ihre herstellung und diese enthaltende therapeutische zusammensetzungen |
HU188311B (en) * | 1982-03-04 | 1986-04-28 | Szendrei,Kalman,Hu | Process for producing biologically active polisaccharide concentrates and pharmaceutical compositions containing them as active agents |
US4400570A (en) * | 1982-05-21 | 1983-08-23 | Cosden Technology, Inc. | Ethylbenzene production employing tea-silicate catalysts |
JPS59122428A (ja) * | 1982-12-28 | 1984-07-14 | Advance Res & Dev Co Ltd | コレステロ−ル低下活性蛋白質 |
JPS59170017A (ja) * | 1983-03-18 | 1984-09-26 | Sapporo Breweries Ltd | 新規多糖体rdp物質,その製造法およびそれを有効成分とする抗腫瘍剤、免疫調節剤および感染症予防治療剤 |
JPS6028401A (ja) * | 1983-07-27 | 1985-02-13 | Advance Res & Dev Co Ltd | トリグリセリド低下活性多糖類 |
JPS6153221A (ja) * | 1984-08-22 | 1986-03-17 | Sapporo Breweries Ltd | 新規多糖体rin物質,その製造法およびそれを有効成分とする抗腫瘍剤,免疫調節剤並びに感染症予防治療剤 |
JPS61151128A (ja) * | 1984-12-24 | 1986-07-09 | Advance Res & Dev Co Ltd | コレステロ−ル低下活性rna画分 |
US6248726B1 (en) * | 1985-06-22 | 2001-06-19 | M L Laboratories Plc | Method of peritoneal dialysis using glucose polymer solutions |
JPS625991A (ja) * | 1985-07-03 | 1987-01-12 | Advance Res & Dev Co Ltd | コレステロ−ル乃至トリグリセリド低下活性rna画分 |
IL85145A (en) * | 1987-01-23 | 1994-08-26 | Univ Australian | Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity |
US5541166A (en) * | 1987-01-23 | 1996-07-30 | The Australian National University | Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity |
US4956458A (en) * | 1988-05-13 | 1990-09-11 | Warner-Lambert Company | Purification of polydextrose by reverse osmosis |
US4950645A (en) * | 1988-07-08 | 1990-08-21 | Immunotherapeutics, Inc. | Composition for macrophage activation |
US5416070A (en) * | 1988-07-08 | 1995-05-16 | Immunotherapeutics, Inc. | Composition for macrophage activation |
PE5591A1 (es) * | 1988-12-19 | 1991-02-15 | Lilly Co Eli | Un nuevo grupo de compuestos de macrolida |
JPH05504469A (ja) * | 1989-10-30 | 1993-07-15 | ダウエランコ | A83543回収方法 |
JPH0678367B2 (ja) * | 1990-05-15 | 1994-10-05 | 呉羽化学工業株式会社 | 食物繊維、その製造法及びその食物繊維を含有する生理活性剤 |
US5591606A (en) * | 1992-11-06 | 1997-01-07 | Dowelanco | Process for the production of A83543 compounds with Saccharopolyspora spinosa |
US5292537A (en) * | 1992-11-12 | 1994-03-08 | Bran Tec, Inc. | Method for stabilizing rice bran and rice bran products |
EP0688332B1 (en) * | 1993-03-12 | 1997-03-26 | Dowelanco | New a83543 compounds and process for production thereof |
US6001981A (en) * | 1996-06-13 | 1999-12-14 | Dow Agrosciences Llc | Synthetic modification of Spinosyn compounds |
US6582723B2 (en) | 2001-05-03 | 2003-06-24 | Wayne F. Gorsek | Cancer immune composition for prevention and treatment of individuals |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51149388A (en) * | 1975-06-17 | 1976-12-22 | Sumitomo Chem Co Ltd | A process for preparing the carboxylated pullulan |
US4152170A (en) * | 1975-06-18 | 1979-05-01 | Sumitomo Chemical Company, Ltd. | Cross-linked pullulan |
JPS53130496A (en) * | 1977-04-15 | 1978-11-14 | Japan Synthetic Rubber Co Ltd | Preparation of polysaccharides |
US4221907A (en) * | 1979-07-09 | 1980-09-09 | American Cyanamid Company | Substituted O-α-D and O-β-D-multi-galactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6 α-D-glucopyranoses |
-
1979
- 1979-08-13 JP JP54102216A patent/JPS5943929B2/ja not_active Expired
-
1980
- 1980-08-01 US US06/174,536 patent/US4357323A/en not_active Expired - Lifetime
- 1980-08-01 US US06/174,537 patent/US4366308A/en not_active Expired - Lifetime
- 1980-08-09 DE DE8080104699T patent/DE3068681D1/de not_active Expired
- 1980-08-09 EP EP80104699A patent/EP0025123B1/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05112455A (ja) * | 1991-06-17 | 1993-05-07 | Snow Brand Milk Prod Co Ltd | 大腸癌抑制物質 |
Also Published As
Publication number | Publication date |
---|---|
EP0025123A2 (en) | 1981-03-18 |
DE3068681D1 (en) | 1984-08-30 |
EP0025123A3 (en) | 1981-03-25 |
US4366308A (en) | 1982-12-28 |
US4357323A (en) | 1982-11-02 |
EP0025123B1 (en) | 1984-07-25 |
JPS5943929B2 (ja) | 1984-10-25 |
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