JPS5535096A - 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent - Google Patents

3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent

Info

Publication number
JPS5535096A
JPS5535096A JP11314779A JP11314779A JPS5535096A JP S5535096 A JPS5535096 A JP S5535096A JP 11314779 A JP11314779 A JP 11314779A JP 11314779 A JP11314779 A JP 11314779A JP S5535096 A JPS5535096 A JP S5535096A
Authority
JP
Japan
Prior art keywords
salt
compound
formula
microbism
thema
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11314779A
Other languages
English (en)
Other versions
JPH0240678B2 (ja
Inventor
Takao Takatani
Takashi Masugi
Hisashi Takasugi
Hiromu Kawachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS5535096A publication Critical patent/JPS5535096A/ja
Publication of JPH0240678B2 publication Critical patent/JPH0240678B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP11314779A 1978-09-04 1979-09-03 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent Granted JPS5535096A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7835435 1978-09-04

Publications (2)

Publication Number Publication Date
JPS5535096A true JPS5535096A (en) 1980-03-11
JPH0240678B2 JPH0240678B2 (ja) 1990-09-12

Family

ID=10499419

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11314779A Granted JPS5535096A (en) 1978-09-04 1979-09-03 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent

Country Status (8)

Country Link
JP (1) JPS5535096A (ja)
BE (1) BE878514A (ja)
CH (1) CH643849A5 (ja)
DE (1) DE2935232A1 (ja)
ES (2) ES483839A1 (ja)
FR (1) FR2434810A1 (ja)
NL (1) NL7906624A (ja)
SE (1) SE7907320L (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5585594A (en) * 1978-11-13 1980-06-27 Fujisawa Pharmaceut Co Ltd Cephem compound and their preparation
JPS55151594A (en) * 1979-05-11 1980-11-26 Erba Carlo Spa Oxyimino substituted cephalosporin heterocyclic derivative
JPS56131591A (en) * 1980-02-20 1981-10-15 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent
JPS57131794A (en) * 1980-12-31 1982-08-14 Fujisawa Pharmaceut Co Ltd Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS59130293A (ja) * 1983-01-04 1984-07-26 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS53119887A (en) * 1977-03-25 1978-10-19 Roussel Uclaf Novel oxime derivative of 33acetoxymethyll 77aminothiazolylacetoamide cephalospolanate process for preparing same and pharmaceutical composition
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation
JPS5484595A (en) * 1977-12-05 1979-07-05 Roussel Uclaf Novel oxime derivatives of 33substituted 77aminothiazolyl acetoamide cephalosporanic acid*their manufacture and pharmateutical composition containing them
JPS54132593A (en) * 1978-03-31 1979-10-15 Roussel Uclaf Novel oosubstituted oxime derivatives of 77aminothiazolylacetoamidecephalosporanic acid*their manufacture*their use as drug and composition containing them
JPS54135793A (en) * 1978-04-07 1979-10-22 Roussel Uclaf Novel cephalosporin derived from 33substitutedd77*22*22aminoo44thiazolyl**22*carboxymethoxy imino*acetoamide* cephalosporanic acid*its manufacture and use as drug and pharmaceutical composition contai
JPS54154790A (en) * 1978-05-26 1979-12-06 Glaxo Group Ltd Cephalosporin antibiotic and its manufacture
JPS54154788A (en) * 1978-05-26 1979-12-06 Glaxo Group Ltd Cephalosporin antibiotic
JPS5519267A (en) * 1978-07-17 1980-02-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid, its salts, their preparation, and preventive and remedy for microbism comprising them as active constituents
JPS5858353A (ja) * 1981-09-30 1983-04-06 ピ−シ−株式会社 強化コンクリ−ト構造体
JPS60142994A (ja) * 1977-03-14 1985-07-29 Fujisawa Pharmaceut Co Ltd セフエム化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
DE2804040C3 (de) * 1978-01-31 1981-03-19 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von Cephemverbindungen
SE7901262L (sv) * 1978-02-15 1979-08-16 Fujisawa Pharmaceutical Co 3,7-disubstituerade 3-cefem-4-karboxylsyraforeningar och forfarande for deras framstellning
NZ190557A (en) * 1978-05-26 1982-05-25 Glaxo Group Ltd Cephalosporin antibiotics and pharmaceutical compositions containing them
AR231986A1 (es) * 1978-05-26 1985-04-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina
IT1116187B (it) * 1978-05-26 1986-02-10 Glaxo Group Ltd Antibiotici cefalosporinici composizioni che li contengono e relativo procedimento di produzione
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS60142994A (ja) * 1977-03-14 1985-07-29 Fujisawa Pharmaceut Co Ltd セフエム化合物
JPS53119887A (en) * 1977-03-25 1978-10-19 Roussel Uclaf Novel oxime derivative of 33acetoxymethyll 77aminothiazolylacetoamide cephalospolanate process for preparing same and pharmaceutical composition
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation
JPS5484595A (en) * 1977-12-05 1979-07-05 Roussel Uclaf Novel oxime derivatives of 33substituted 77aminothiazolyl acetoamide cephalosporanic acid*their manufacture and pharmateutical composition containing them
JPS54132593A (en) * 1978-03-31 1979-10-15 Roussel Uclaf Novel oosubstituted oxime derivatives of 77aminothiazolylacetoamidecephalosporanic acid*their manufacture*their use as drug and composition containing them
JPS54135793A (en) * 1978-04-07 1979-10-22 Roussel Uclaf Novel cephalosporin derived from 33substitutedd77*22*22aminoo44thiazolyl**22*carboxymethoxy imino*acetoamide* cephalosporanic acid*its manufacture and use as drug and pharmaceutical composition contai
JPS54154790A (en) * 1978-05-26 1979-12-06 Glaxo Group Ltd Cephalosporin antibiotic and its manufacture
JPS54154788A (en) * 1978-05-26 1979-12-06 Glaxo Group Ltd Cephalosporin antibiotic
JPS54154789A (en) * 1978-05-26 1979-12-06 Glaxo Group Ltd Cephalosporin antibiotic
JPS5519267A (en) * 1978-07-17 1980-02-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid, its salts, their preparation, and preventive and remedy for microbism comprising them as active constituents
JPS5858353A (ja) * 1981-09-30 1983-04-06 ピ−シ−株式会社 強化コンクリ−ト構造体

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5585594A (en) * 1978-11-13 1980-06-27 Fujisawa Pharmaceut Co Ltd Cephem compound and their preparation
JPH0144713B2 (ja) * 1978-11-13 1989-09-29 Fujisawa Pharmaceutical Co
JPS55151594A (en) * 1979-05-11 1980-11-26 Erba Carlo Spa Oxyimino substituted cephalosporin heterocyclic derivative
JPS56131591A (en) * 1980-02-20 1981-10-15 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent
JPS57131794A (en) * 1980-12-31 1982-08-14 Fujisawa Pharmaceut Co Ltd Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS59130293A (ja) * 1983-01-04 1984-07-26 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造方法

Also Published As

Publication number Publication date
BE878514A (fr) 1980-02-29
SE7907320L (sv) 1980-03-05
NL7906624A (nl) 1980-03-06
ES8102142A1 (es) 1980-12-16
CH643849A5 (en) 1984-06-29
JPH0240678B2 (ja) 1990-09-12
FR2434810B1 (ja) 1983-06-03
FR2434810A1 (fr) 1980-03-28
ES490888A0 (es) 1980-12-16
DE2935232A1 (de) 1980-03-13
ES483839A1 (es) 1980-09-01

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