JPS5246093A - 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof - Google Patents

2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof

Info

Publication number
JPS5246093A
JPS5246093A JP51115675A JP11567576A JPS5246093A JP S5246093 A JPS5246093 A JP S5246093A JP 51115675 A JP51115675 A JP 51115675A JP 11567576 A JP11567576 A JP 11567576A JP S5246093 A JPS5246093 A JP S5246093A
Authority
JP
Japan
Prior art keywords
cephem
alkyl
sal
substituted
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51115675A
Other languages
Japanese (ja)
Other versions
JPS6139952B2 (en
Inventor
Takashi Kamiya
Tsutomu Terachi
Shinji Hashimoto
Osamu Nakaguchi
Teruo Oku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB4067775A external-priority patent/GB1554723A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS5246093A publication Critical patent/JPS5246093A/en
Publication of JPS6139952B2 publication Critical patent/JPS6139952B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

PURPOSE: Title compounds of formula I(R1 is alkyl;R2 is carboxy, protected carboxy;R3 is amino, protected amino;A is alkylene);for example,2methyl-7-[2-(2-aminothiazol-4-yl)acetamido]-3-cephem-4-carboxylic acid.
COPYRIGHT: (C)1977,JPO&Japio
JP51115675A 1975-10-03 1976-09-27 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof Granted JPS5246093A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4067775A GB1554723A (en) 1975-10-03 1975-10-03 Cephalosporin derivatives and the preparation thereof
GB5049875 1975-12-09

Publications (2)

Publication Number Publication Date
JPS5246093A true JPS5246093A (en) 1977-04-12
JPS6139952B2 JPS6139952B2 (en) 1986-09-06

Family

ID=26264472

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51115675A Granted JPS5246093A (en) 1975-10-03 1976-09-27 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof

Country Status (5)

Country Link
JP (1) JPS5246093A (en)
AT (1) AT352272B (en)
DE (1) DE2644335A1 (en)
FR (1) FR2326196A1 (en)
NL (1) NL7610898A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55166637A (en) * 1979-06-12 1980-12-25 Konishiroku Photo Ind Co Ltd Manufacture of silver halide photographic emulsion
JPS561041A (en) * 1979-06-16 1981-01-08 Konishiroku Photo Ind Co Ltd Manufacture of silver halide photographic emulsion
JPS56109335A (en) * 1980-02-05 1981-08-29 Konishiroku Photo Ind Co Ltd Manufacture of silver halide photographic emulsion

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI771866A (en) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
KR20200145870A (en) 2019-06-10 2020-12-31 삼성전자주식회사 Semiconductor device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55166637A (en) * 1979-06-12 1980-12-25 Konishiroku Photo Ind Co Ltd Manufacture of silver halide photographic emulsion
JPS561041A (en) * 1979-06-16 1981-01-08 Konishiroku Photo Ind Co Ltd Manufacture of silver halide photographic emulsion
JPS56109335A (en) * 1980-02-05 1981-08-29 Konishiroku Photo Ind Co Ltd Manufacture of silver halide photographic emulsion
JPH0160810B2 (en) * 1980-02-05 1989-12-26 Konishiroku Photo Ind

Also Published As

Publication number Publication date
AT352272B (en) 1979-09-10
JPS6139952B2 (en) 1986-09-06
FR2326196B1 (en) 1980-04-18
NL7610898A (en) 1977-04-05
ATA727576A (en) 1979-02-15
FR2326196A1 (en) 1977-04-29
DE2644335A1 (en) 1977-04-14

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