JPH0829111B2 - 酵母菌による異種構造のタンパク質の発現、プロセシングおよび分泌 - Google Patents

酵母菌による異種構造のタンパク質の発現、プロセシングおよび分泌

Info

Publication number
JPH0829111B2
JPH0829111B2 JP58038116A JP3811683A JPH0829111B2 JP H0829111 B2 JPH0829111 B2 JP H0829111B2 JP 58038116 A JP58038116 A JP 58038116A JP 3811683 A JP3811683 A JP 3811683A JP H0829111 B2 JPH0829111 B2 JP H0829111B2
Authority
JP
Japan
Prior art keywords
yeast
fragment
gene
protein
eco
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58038116A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58174396A (ja
Inventor
ロナルド・ア−サ−・ハイツマン
デビツド・ウエイ−フン・リユン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26998782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0829111(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JPS58174396A publication Critical patent/JPS58174396A/ja
Publication of JPH0829111B2 publication Critical patent/JPH0829111B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Lubricants (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
JP58038116A 1982-03-08 1983-03-08 酵母菌による異種構造のタンパク質の発現、プロセシングおよび分泌 Expired - Lifetime JPH0829111B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35529782A 1982-03-08 1982-03-08
US355297 1982-03-08
US438236 1982-11-01
US06/438,236 US4775622A (en) 1982-03-08 1982-11-01 Expression, processing and secretion of heterologous protein by yeast

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP5093196A Division JPH06181779A (ja) 1982-03-08 1993-04-20 酵母菌による異種タンパク質の分泌

Publications (2)

Publication Number Publication Date
JPS58174396A JPS58174396A (ja) 1983-10-13
JPH0829111B2 true JPH0829111B2 (ja) 1996-03-27

Family

ID=26998782

Family Applications (2)

Application Number Title Priority Date Filing Date
JP58038116A Expired - Lifetime JPH0829111B2 (ja) 1982-03-08 1983-03-08 酵母菌による異種構造のタンパク質の発現、プロセシングおよび分泌
JP5093196A Pending JPH06181779A (ja) 1982-03-08 1993-04-20 酵母菌による異種タンパク質の分泌

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP5093196A Pending JPH06181779A (ja) 1982-03-08 1993-04-20 酵母菌による異種タンパク質の分泌

Country Status (28)

Country Link
US (1) US4775622A (OSRAM)
EP (1) EP0088632B1 (OSRAM)
JP (2) JPH0829111B2 (OSRAM)
AU (1) AU574323B2 (OSRAM)
BG (1) BG46159A3 (OSRAM)
BR (1) BR8301150A (OSRAM)
CZ (1) CZ282905B6 (OSRAM)
DD (1) DD207220A5 (OSRAM)
DE (2) DE3308215C2 (OSRAM)
DK (1) DK163932C (OSRAM)
DZ (1) DZ513A1 (OSRAM)
ES (1) ES8500324A1 (OSRAM)
FI (1) FI830774A7 (OSRAM)
FR (1) FR2523152B1 (OSRAM)
GB (1) GB2116567B (OSRAM)
GR (1) GR78506B (OSRAM)
IE (1) IE55743B1 (OSRAM)
IL (1) IL68058A (OSRAM)
MX (1) MX163813B (OSRAM)
NO (1) NO830780L (OSRAM)
NZ (1) NZ203494A (OSRAM)
OA (1) OA07338A (OSRAM)
PH (1) PH24804A (OSRAM)
PL (1) PL153724B1 (OSRAM)
PT (1) PT76360B (OSRAM)
RO (1) RO88582A (OSRAM)
YU (1) YU46723B (OSRAM)
ZW (1) ZW6283A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7531631B2 (en) 2004-01-20 2009-05-12 Juridical Foundation The Chemoserotherapeutic Research Institute Method for preparing human serum albumin through heat-treatment in the presence of divalent cation

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