DE3382694D1 - Expression, bearbeitung und ausscheidung von heterologem protein durch hefen. - Google Patents

Expression, bearbeitung und ausscheidung von heterologem protein durch hefen.

Info

Publication number
DE3382694D1
DE3382694D1 DE8383301269T DE3382694T DE3382694D1 DE 3382694 D1 DE3382694 D1 DE 3382694D1 DE 8383301269 T DE8383301269 T DE 8383301269T DE 3382694 T DE3382694 T DE 3382694T DE 3382694 D1 DE3382694 D1 DE 3382694D1
Authority
DE
Germany
Prior art keywords
yeast
expression
separation
processing
heterological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8383301269T
Other languages
English (en)
Other versions
DE3382694T2 (de
Inventor
Ronald Arthur Hitzeman
David Wai-Hung Leung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26998782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3382694(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE3382694D1 publication Critical patent/DE3382694D1/de
Publication of DE3382694T2 publication Critical patent/DE3382694T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Lubricants (AREA)
DE8383301269T 1982-03-08 1983-03-08 Expression, bearbeitung und ausscheidung von heterologem protein durch hefen. Expired - Lifetime DE3382694T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35529782A 1982-03-08 1982-03-08
US06/438,236 US4775622A (en) 1982-03-08 1982-11-01 Expression, processing and secretion of heterologous protein by yeast

Publications (2)

Publication Number Publication Date
DE3382694D1 true DE3382694D1 (de) 1993-07-22
DE3382694T2 DE3382694T2 (de) 1993-09-23

Family

ID=26998782

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3308215A Expired - Lifetime DE3308215C2 (de) 1982-03-08 1983-03-08 Expression, Processing und Sekretion von heterologem Protein durch Hefe
DE8383301269T Expired - Lifetime DE3382694T2 (de) 1982-03-08 1983-03-08 Expression, bearbeitung und ausscheidung von heterologem protein durch hefen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3308215A Expired - Lifetime DE3308215C2 (de) 1982-03-08 1983-03-08 Expression, Processing und Sekretion von heterologem Protein durch Hefe

Country Status (28)

Country Link
US (1) US4775622A (de)
EP (1) EP0088632B1 (de)
JP (2) JPH0829111B2 (de)
AU (1) AU574323B2 (de)
BG (1) BG46159A3 (de)
BR (1) BR8301150A (de)
CZ (1) CZ282905B6 (de)
DD (1) DD207220A5 (de)
DE (2) DE3308215C2 (de)
DK (1) DK163932C (de)
DZ (1) DZ513A1 (de)
ES (1) ES8500324A1 (de)
FI (1) FI830774L (de)
FR (1) FR2523152B1 (de)
GB (1) GB2116567B (de)
GR (1) GR78506B (de)
IE (1) IE55743B1 (de)
IL (1) IL68058A (de)
MX (1) MX163813B (de)
NO (1) NO830780L (de)
NZ (1) NZ203494A (de)
OA (1) OA07338A (de)
PH (1) PH24804A (de)
PL (1) PL153724B1 (de)
PT (1) PT76360B (de)
RO (1) RO88582A (de)
YU (1) YU46723B (de)
ZW (1) ZW6283A1 (de)

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* Cited by examiner, † Cited by third party
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GB2116567A (en) 1983-09-28
FR2523152B1 (fr) 1985-08-23
DK111283A (da) 1983-10-28
ES520416A0 (es) 1984-11-01
EP0088632A2 (de) 1983-09-14
YU55683A (en) 1989-08-31
PL153724B1 (en) 1991-05-31
US4775622A (en) 1988-10-04
DK163932C (da) 1996-12-23
CZ160883A3 (en) 1997-07-16
PH24804A (en) 1990-10-30
JPH06181779A (ja) 1994-07-05
YU46723B (sh) 1994-04-05
IE830498L (en) 1983-09-08
DK163932B (da) 1992-04-21
ZW6283A1 (en) 1983-06-01
AU1215283A (en) 1983-09-15
PL240927A1 (en) 1983-11-07
PT76360B (en) 1986-02-12
IL68058A (en) 1989-12-15
RO88582A (ro) 1986-02-28
NZ203494A (en) 1986-06-11
EP0088632A3 (en) 1984-06-20
GR78506B (de) 1984-09-27
CZ282905B6 (cs) 1997-11-12
JPS58174396A (ja) 1983-10-13
DE3308215A1 (de) 1983-11-17
DZ513A1 (fr) 2004-09-13
DE3382694T2 (de) 1993-09-23
JPH0829111B2 (ja) 1996-03-27
MX163813B (es) 1992-06-22
ES8500324A1 (es) 1984-11-01
FR2523152A1 (fr) 1983-09-16
BR8301150A (pt) 1983-11-22
GB2116567B (en) 1986-01-02
OA07338A (fr) 1984-08-31
IE55743B1 (en) 1991-01-02
DK111283D0 (da) 1983-03-07
DD207220A5 (de) 1984-02-22
DE3308215C2 (de) 1994-01-27
FI830774L (fi) 1983-09-09
NO830780L (no) 1983-09-09
IL68058A0 (en) 1983-06-15
PT76360A (en) 1983-04-01
FI830774A0 (fi) 1983-03-08
EP0088632B1 (de) 1993-06-16
AU574323B2 (en) 1988-07-07
BG46159A3 (en) 1989-10-16
GB8306285D0 (en) 1983-04-13

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