JPH0671432B2 - ヒト血清アルブミンの製造方法 - Google Patents

ヒト血清アルブミンの製造方法

Info

Publication number
JPH0671432B2
JPH0671432B2 JP3081719A JP8171991A JPH0671432B2 JP H0671432 B2 JPH0671432 B2 JP H0671432B2 JP 3081719 A JP3081719 A JP 3081719A JP 8171991 A JP8171991 A JP 8171991A JP H0671432 B2 JPH0671432 B2 JP H0671432B2
Authority
JP
Japan
Prior art keywords
medium
hsa
culture
serum albumin
human serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP3081719A
Other languages
English (en)
Japanese (ja)
Other versions
JPH04293495A (ja
Inventor
薫 小林
忍 桑江
智資 大屋
浩利 福塚
昭典 鷲見
渡 大谷
孝男 大村
和正 横山
Original Assignee
株式会社ミドリ十字
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社ミドリ十字 filed Critical 株式会社ミドリ十字
Priority to JP3081719A priority Critical patent/JPH0671432B2/ja
Priority to TW081101744A priority patent/TW198683B/zh
Priority to DE69220113T priority patent/DE69220113T2/de
Priority to DK92104625.6T priority patent/DK0504823T3/da
Priority to EP92104625A priority patent/EP0504823B1/en
Priority to ES92104625T priority patent/ES2102420T3/es
Priority to CA002063511A priority patent/CA2063511C/en
Priority to KR1019920004650A priority patent/KR100218853B1/ko
Priority to US07/854,841 priority patent/US5334512A/en
Publication of JPH04293495A publication Critical patent/JPH04293495A/ja
Publication of JPH0671432B2 publication Critical patent/JPH0671432B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP3081719A 1991-03-20 1991-03-20 ヒト血清アルブミンの製造方法 Expired - Lifetime JPH0671432B2 (ja)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP3081719A JPH0671432B2 (ja) 1991-03-20 1991-03-20 ヒト血清アルブミンの製造方法
TW081101744A TW198683B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-03-20 1992-03-07
DE69220113T DE69220113T2 (de) 1991-03-20 1992-03-18 Verfahren zur Herstellung von menschlichem Serum Albumin
DK92104625.6T DK0504823T3 (da) 1991-03-20 1992-03-18 Fremgangsmåde til fremstilling af human serumalbumin
EP92104625A EP0504823B1 (en) 1991-03-20 1992-03-18 Method for producing human serum albumin
ES92104625T ES2102420T3 (es) 1991-03-20 1992-03-18 Metodo para la produccion de albumina de suero humano.
CA002063511A CA2063511C (en) 1991-03-20 1992-03-19 Method for producing human serum albumin
KR1019920004650A KR100218853B1 (ko) 1991-03-20 1992-03-20 인체 혈청 알부민의 제조방법
US07/854,841 US5334512A (en) 1991-03-20 1992-03-20 Fatty acid supplemented medium for recombinant production of human serum albumin by yeast

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3081719A JPH0671432B2 (ja) 1991-03-20 1991-03-20 ヒト血清アルブミンの製造方法

Publications (2)

Publication Number Publication Date
JPH04293495A JPH04293495A (ja) 1992-10-19
JPH0671432B2 true JPH0671432B2 (ja) 1994-09-14

Family

ID=13754223

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3081719A Expired - Lifetime JPH0671432B2 (ja) 1991-03-20 1991-03-20 ヒト血清アルブミンの製造方法

Country Status (9)

Country Link
US (1) US5334512A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0504823B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0671432B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100218853B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2063511C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69220113T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0504823T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2102420T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW198683B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
CA2136564C (en) * 1993-11-26 2008-04-08 Kaoru Kobayashi Process for producing human serum albumin
JPH07308199A (ja) 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
ES2255154T3 (es) * 1997-04-03 2006-06-16 Mitsubishi Pharma Corporation Procedimiento para producir proteinas foraneas.
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
WO2005115121A2 (en) * 2004-05-26 2005-12-08 University Of Medicine And Dentistry Of New Jersey Adenylyl cyclase antibodies, compositions and uses thereof
WO2006066595A2 (en) * 2004-12-22 2006-06-29 Novozymes A/S Recombinant production of serum albumin
CA2724052A1 (en) * 2008-05-15 2009-11-19 R-Tech Ueno, Ltd. Pharmaceutical composition for the treatment of dry eye and/or corneal and conjunctival lesion
CN110290786A (zh) * 2016-12-21 2019-09-27 普罗米蒂克医药Smt有限公司 用于预防或最小化上皮细胞-间充质细胞转换的方法和组合物
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
CN116744984A (zh) 2020-12-28 2023-09-12 达沃有限公司 包含蛋白质和多官能化改性的基于聚乙二醇的交联剂的反应性干粉状止血材料
KR20240032272A (ko) 2022-09-02 2024-03-12 조신아 아동원예지도사 교육방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
EP0079739A3 (en) * 1981-11-12 1984-08-08 The Upjohn Company Albumin-based nucleotides, their replication and use, and plasmids for use therein
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
KR870000428A (ko) * 1985-06-17 1987-02-18 . 인체혈청 알부민의 제조방법
DK13087A (da) * 1986-01-13 1987-07-14 Genex Corp Gensekvens til fremstilling af human serumalbumin i bacillus
GB8613388D0 (en) * 1986-06-03 1986-07-09 Delta Biotechnology Ltd Induction of galactose regulated gene expression in yeast
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
JPS6460370A (en) * 1987-05-27 1989-03-07 Sankyo Co High-temperature culture of yeast
US5024947A (en) * 1987-07-24 1991-06-18 Cetus Corporation Serum free media for the growth on insect cells and expression of products thereby
JP2791418B2 (ja) * 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
JPH01240191A (ja) * 1988-02-16 1989-09-25 Green Cross Corp:The 酵母で機能する新規シグナルペプチドおよびこれを用いた異種蛋白質の分泌発現
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
GB8820951D0 (en) * 1988-09-07 1988-10-05 Delta Biotechnology Ltd Fermentation method
CA2017176A1 (en) * 1989-05-22 1990-11-22 Yoshitomi Pharmaceutical Industries Ltd. Albumin gene-containing plasmid, transformant carrying same, production of such transformant and production of albumin
JP2855130B2 (ja) * 1989-07-19 1999-02-10 吉富製薬株式会社 異種蛋白発現用融合酵母菌、該菌の製造方法および異種蛋白の製造方法
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法

Also Published As

Publication number Publication date
DE69220113T2 (de) 1997-09-25
EP0504823B1 (en) 1997-06-04
CA2063511C (en) 2001-11-27
KR100218853B1 (ko) 1999-10-01
DE69220113D1 (de) 1997-07-10
JPH04293495A (ja) 1992-10-19
KR920018218A (ko) 1992-10-21
EP0504823A3 (en) 1993-04-07
ES2102420T3 (es) 1997-08-01
CA2063511A1 (en) 1992-09-21
US5334512A (en) 1994-08-02
TW198683B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-01-21
EP0504823A2 (en) 1992-09-23
DK0504823T3 (da) 1997-06-23

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