DE68907166T2 - Verfahren zur Herstellung von menschlichem Lysozym. - Google Patents

Verfahren zur Herstellung von menschlichem Lysozym.

Info

Publication number
DE68907166T2
DE68907166T2 DE89870140T DE68907166T DE68907166T2 DE 68907166 T2 DE68907166 T2 DE 68907166T2 DE 89870140 T DE89870140 T DE 89870140T DE 68907166 T DE68907166 T DE 68907166T DE 68907166 T2 DE68907166 T2 DE 68907166T2
Authority
DE
Germany
Prior art keywords
lysozyme
production
human lysozyme
produce
secrete
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89870140T
Other languages
English (en)
Other versions
DE68907166D1 (de
Inventor
Baetselier Annie De
Steven Rosenberg
Jacques D V Hanotier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Total Research and Technology Feluy SA
Novartis Vaccines and Diagnostics Inc
Original Assignee
Fina Research SA
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fina Research SA, Chiron Corp filed Critical Fina Research SA
Publication of DE68907166D1 publication Critical patent/DE68907166D1/de
Application granted granted Critical
Publication of DE68907166T2 publication Critical patent/DE68907166T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE89870140T 1988-09-26 1989-09-25 Verfahren zur Herstellung von menschlichem Lysozym. Expired - Lifetime DE68907166T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24941388A 1988-09-26 1988-09-26

Publications (2)

Publication Number Publication Date
DE68907166D1 DE68907166D1 (de) 1993-07-22
DE68907166T2 true DE68907166T2 (de) 1993-10-21

Family

ID=22943380

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89870140T Expired - Lifetime DE68907166T2 (de) 1988-09-26 1989-09-25 Verfahren zur Herstellung von menschlichem Lysozym.

Country Status (10)

Country Link
US (1) US5585257A (de)
EP (1) EP0362183B1 (de)
JP (1) JP2905230B2 (de)
AT (1) ATE90726T1 (de)
DE (1) DE68907166T2 (de)
DK (1) DK175315B1 (de)
ES (1) ES2057183T3 (de)
IE (1) IE63964B1 (de)
NO (1) NO177065C (de)
RU (1) RU2060275C1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03155791A (ja) * 1989-11-14 1991-07-03 Green Cross Corp:The 雑種プロモーター
US20080050503A1 (en) * 2000-05-02 2008-02-28 Ning Huang Expression of human milk proteins in transgenic plants
US7417178B2 (en) * 2000-05-02 2008-08-26 Ventria Bioscience Expression of human milk proteins in transgenic plants
US7138150B2 (en) * 2000-05-02 2006-11-21 Ventria Bioscience Method of making an anti-infective composition for treating oral infections
WO2002085932A2 (en) * 2001-04-24 2002-10-31 Innogenetics N.V. Constructs and methods for expression of recombinant hcv envelope proteins
WO2005061532A1 (es) * 2003-12-23 2005-07-07 Berthet Francois Xavier Composiciones y procedimientos para detectar infección patógena
CN100451119C (zh) * 2005-12-08 2009-01-14 辽宁省农业科学院大连生物技术研究所 柞蚕溶菌酶的基因序列及其表达产物的制备方法
CN105567714A (zh) * 2014-11-07 2016-05-11 西南民族大学 一种重组牦牛溶菌酶及其制备方法和用途
EP4263823A1 (de) * 2020-12-16 2023-10-25 Danisco US Inc Enzyme und enzymzusammensetzungen zur reinigung

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595658A (en) * 1982-09-13 1986-06-17 The Rockefeller University Method for facilitating externalization of proteins synthesized in bacteria
US4624922A (en) * 1983-12-09 1986-11-25 Rikagaku Kenkyusho Plasmid, method for construction of the same, microorganism carrying the plasmid and method for cultivation of the microorganism
US4880734A (en) * 1984-05-11 1989-11-14 Chiron Corporation Eukaryotic regulatable transcription
EP0164556B1 (de) * 1984-05-11 1994-03-02 Chiron Corporation Erhöhte Hefetranskription unter Verwendung einer Hybridkonstruktion der Promotorregion
US4767708A (en) * 1984-08-07 1988-08-30 Carnegie Mellon University Enzyme amplification and purification
BE901223A (fr) * 1984-12-06 1985-03-29 Labofina Sa Levures transformees produisant du lysozyme plasmides utilises pour cette transformation et leurs utilisations.
JPS626679A (ja) * 1985-06-26 1987-01-13 Agency Of Ind Science & Technol ヒトリゾチ−ムの微生物学的製造法
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
BE903626A (fr) * 1985-11-13 1986-03-03 Labofina Sa Procede pour la recuperation de polypeptides localises dans l'espace periplasmique de la levure.
US5124256A (en) * 1985-11-13 1992-06-23 Labofina, S.A. Process for recovering polypeptides localized in the periplasmic space of yeast without breaking the cell wall by using an non-ionic detergent and a neutral salt
IL83435A (en) * 1986-09-23 1993-01-14 Miles Lab Dna construct for expression of genes in yeast, an expression vector containing it and yeast transformed with said expression vector

Also Published As

Publication number Publication date
ATE90726T1 (de) 1993-07-15
NO177065B (no) 1995-04-03
JP2905230B2 (ja) 1999-06-14
DK175315B1 (da) 2004-08-16
NO893553L (no) 1990-03-27
IE893053L (en) 1990-03-26
EP0362183A3 (en) 1990-08-08
EP0362183B1 (de) 1993-06-16
US5585257A (en) 1996-12-17
DE68907166D1 (de) 1993-07-22
NO177065C (no) 1995-07-12
JPH02156885A (ja) 1990-06-15
EP0362183A2 (de) 1990-04-04
ES2057183T3 (es) 1994-10-16
NO893553D0 (no) 1989-09-05
DK460389D0 (da) 1989-09-19
RU2060275C1 (ru) 1996-05-20
IE63964B1 (en) 1995-06-28
DK460389A (da) 1990-03-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: ACKMANN MENGES PATENT- UND RECHTSANWAELTE, 80469 M