JPH06104668B2 - チエノ‐トリアゾロ‐ジアゼピンのチオメチル誘導体、その製造方法及びそれを含有する医薬組成物 - Google Patents

チエノ‐トリアゾロ‐ジアゼピンのチオメチル誘導体、その製造方法及びそれを含有する医薬組成物

Info

Publication number
JPH06104668B2
JPH06104668B2 JP2120188A JP12018890A JPH06104668B2 JP H06104668 B2 JPH06104668 B2 JP H06104668B2 JP 2120188 A JP2120188 A JP 2120188A JP 12018890 A JP12018890 A JP 12018890A JP H06104668 B2 JPH06104668 B2 JP H06104668B2
Authority
JP
Japan
Prior art keywords
thieno
triazolo
diazepine
compound
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2120188A
Other languages
English (en)
Japanese (ja)
Other versions
JPH035484A (ja
Inventor
ブラツク・ピエール
エサヌ・アンドル
ローラン・ジヤン‐ピエール
ポミエ・ジヤツク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of JPH035484A publication Critical patent/JPH035484A/ja
Publication of JPH06104668B2 publication Critical patent/JPH06104668B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2120188A 1989-05-13 1990-05-11 チエノ‐トリアゾロ‐ジアゼピンのチオメチル誘導体、その製造方法及びそれを含有する医薬組成物 Expired - Lifetime JPH06104668B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8911030.8 1989-05-13
GB898911030A GB8911030D0 (en) 1989-05-13 1989-05-13 Hetrazepine derivatives

Publications (2)

Publication Number Publication Date
JPH035484A JPH035484A (ja) 1991-01-11
JPH06104668B2 true JPH06104668B2 (ja) 1994-12-21

Family

ID=10656702

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2120188A Expired - Lifetime JPH06104668B2 (ja) 1989-05-13 1990-05-11 チエノ‐トリアゾロ‐ジアゼピンのチオメチル誘導体、その製造方法及びそれを含有する医薬組成物

Country Status (32)

Country Link
US (1) US5049559A (enFirst)
JP (1) JPH06104668B2 (enFirst)
KR (1) KR900018113A (enFirst)
AR (1) AR245725A1 (enFirst)
AT (1) AT399153B (enFirst)
AU (1) AU628171B2 (enFirst)
BE (1) BE1004122A3 (enFirst)
CA (1) CA2016551C (enFirst)
CH (1) CH681009A5 (enFirst)
DE (1) DE4015137C2 (enFirst)
DK (1) DK102990A (enFirst)
DZ (1) DZ1414A1 (enFirst)
ES (1) ES2019840A6 (enFirst)
FI (1) FI93119C (enFirst)
FR (2) FR2646851B1 (enFirst)
GB (2) GB8911030D0 (enFirst)
GR (1) GR1000295B (enFirst)
HK (1) HK94992A (enFirst)
IE (1) IE65246B1 (enFirst)
IN (1) IN174000B (enFirst)
IT (1) IT1240935B (enFirst)
LU (1) LU87733A1 (enFirst)
MA (1) MA21842A1 (enFirst)
NL (1) NL9001089A (enFirst)
NO (1) NO173607C (enFirst)
NZ (1) NZ233574A (enFirst)
OA (1) OA09209A (enFirst)
PT (1) PT94008B (enFirst)
SE (1) SE505407C2 (enFirst)
SG (1) SG91992G (enFirst)
TN (1) TNSN90061A1 (enFirst)
ZA (1) ZA903305B (enFirst)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304553A (en) * 1988-10-31 1994-04-19 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
US5382579A (en) * 1988-10-31 1995-01-17 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5221671A (en) * 1988-10-31 1993-06-22 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
US5468740A (en) * 1988-10-31 1995-11-21 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
AT394563B (de) * 1990-05-09 1992-05-11 Scras Verfahren zur herstellung von thieno-triazolodiazepinderivaten
GB9207645D0 (en) * 1992-04-08 1992-05-27 Smithkline Beecham Corp Methods
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
US6262044B1 (en) * 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
FR2779652B1 (fr) * 1998-06-15 2001-06-08 Sod Conseils Rech Applic Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
US6987105B2 (en) * 2000-04-28 2006-01-17 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis and use of thienotriazolodiazepines
NZ577031A (en) 2003-05-30 2010-09-30 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as HMG-CO inhibitors
WO2007054896A1 (en) 2005-11-08 2007-05-18 Ranbaxy Laboratories Limited Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
DE3724031A1 (de) * 1986-07-22 1988-01-28 Boehringer Ingelheim Kg Neue hetrazepine und verfahren zu ihrer herstellung
EP0316456A4 (en) * 1987-06-08 1990-05-14 Yoshitomi Pharmaceutical Ester-substituted thienotriazolodiazepine compounds and their medicinal use.

Also Published As

Publication number Publication date
FR2646851B1 (fr) 1992-02-14
MA21842A1 (fr) 1990-12-31
NL9001089A (nl) 1990-12-03
GR1000295B (el) 1992-05-12
GR900100319A (en) 1991-10-10
IE901583L (en) 1990-11-13
FR2646774B1 (fr) 1992-02-14
DK102990A (da) 1990-11-14
NO173607C (no) 1994-01-05
LU87733A1 (fr) 1990-09-19
IT9020276A1 (it) 1991-11-11
HK94992A (en) 1992-12-04
SG91992G (en) 1992-12-04
TNSN90061A1 (fr) 1991-03-05
ES2019840A6 (es) 1991-07-01
FI93119C (fi) 1995-02-27
AT399153B (de) 1995-03-27
US5049559A (en) 1991-09-17
CA2016551C (en) 1997-09-09
CA2016551A1 (en) 1990-11-13
NO173607B (no) 1993-09-27
DE4015137C2 (de) 2003-06-12
NO901813L (no) 1990-11-14
SE9001670D0 (sv) 1990-05-09
PT94008B (pt) 1996-12-31
DK102990D0 (da) 1990-04-26
IN174000B (enFirst) 1994-08-20
IT1240935B (it) 1993-12-27
FR2646774A1 (fr) 1990-11-16
AU628171B2 (en) 1992-09-10
ATA95690A (de) 1994-08-15
IE65246B1 (en) 1995-10-04
CH681009A5 (en) 1992-12-31
JPH035484A (ja) 1991-01-11
NO901813D0 (no) 1990-04-24
GB2231330A (en) 1990-11-14
DE4015137A1 (de) 1990-11-15
SE505407C2 (sv) 1997-08-25
IT9020276A0 (it) 1990-05-11
AR245725A1 (es) 1994-02-28
FR2646851A1 (fr) 1990-11-16
DZ1414A1 (fr) 2004-09-13
PT94008A (pt) 1991-01-08
AU5493190A (en) 1990-11-15
FI902355A0 (fi) 1990-05-11
KR900018113A (ko) 1990-12-20
GB9010403D0 (en) 1990-06-27
BE1004122A3 (fr) 1992-09-29
FI93119B (fi) 1994-11-15
OA09209A (fr) 1992-06-30
GB8911030D0 (en) 1989-06-28
ZA903305B (en) 1991-02-27
NZ233574A (en) 1991-07-26
SE9001670L (enFirst)
GB2231330B (en) 1992-04-29

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