FR2646851B1 - Derives de la thieno-triazolo-diazepine, ainsi qu'un procede de preparation desdits composes - Google Patents

Derives de la thieno-triazolo-diazepine, ainsi qu'un procede de preparation desdits composes

Info

Publication number
FR2646851B1
FR2646851B1 FR909005881A FR9005881A FR2646851B1 FR 2646851 B1 FR2646851 B1 FR 2646851B1 FR 909005881 A FR909005881 A FR 909005881A FR 9005881 A FR9005881 A FR 9005881A FR 2646851 B1 FR2646851 B1 FR 2646851B1
Authority
FR
France
Prior art keywords
thieno
triazolo
compounds
preparation
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR909005881A
Other languages
English (en)
Other versions
FR2646851A1 (fr
Inventor
Pierre Braquet
Jean-Pierre Laurent
Andre Esanu
Jacques Pommier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of FR2646851A1 publication Critical patent/FR2646851A1/fr
Application granted granted Critical
Publication of FR2646851B1 publication Critical patent/FR2646851B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR909005881A 1989-05-13 1990-05-11 Derives de la thieno-triazolo-diazepine, ainsi qu'un procede de preparation desdits composes Expired - Fee Related FR2646851B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898911030A GB8911030D0 (en) 1989-05-13 1989-05-13 Hetrazepine derivatives

Publications (2)

Publication Number Publication Date
FR2646851A1 FR2646851A1 (fr) 1990-11-16
FR2646851B1 true FR2646851B1 (fr) 1992-02-14

Family

ID=10656702

Family Applications (2)

Application Number Title Priority Date Filing Date
FR909005880A Expired - Fee Related FR2646774B1 (fr) 1989-05-13 1990-05-11 Compositions therapeutiques a base de nouveaux derives de thieno-triazolo-diazepine
FR909005881A Expired - Fee Related FR2646851B1 (fr) 1989-05-13 1990-05-11 Derives de la thieno-triazolo-diazepine, ainsi qu'un procede de preparation desdits composes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR909005880A Expired - Fee Related FR2646774B1 (fr) 1989-05-13 1990-05-11 Compositions therapeutiques a base de nouveaux derives de thieno-triazolo-diazepine

Country Status (32)

Country Link
US (1) US5049559A (fr)
JP (1) JPH06104668B2 (fr)
KR (1) KR900018113A (fr)
AR (1) AR245725A1 (fr)
AT (1) AT399153B (fr)
AU (1) AU628171B2 (fr)
BE (1) BE1004122A3 (fr)
CA (1) CA2016551C (fr)
CH (1) CH681009A5 (fr)
DE (1) DE4015137C2 (fr)
DK (1) DK102990A (fr)
DZ (1) DZ1414A1 (fr)
ES (1) ES2019840A6 (fr)
FI (1) FI93119C (fr)
FR (2) FR2646774B1 (fr)
GB (2) GB8911030D0 (fr)
GR (1) GR1000295B (fr)
HK (1) HK94992A (fr)
IE (1) IE65246B1 (fr)
IN (1) IN174000B (fr)
IT (1) IT1240935B (fr)
LU (1) LU87733A1 (fr)
MA (1) MA21842A1 (fr)
NL (1) NL9001089A (fr)
NO (1) NO173607C (fr)
NZ (1) NZ233574A (fr)
OA (1) OA09209A (fr)
PT (1) PT94008B (fr)
SE (1) SE505407C2 (fr)
SG (1) SG91992G (fr)
TN (1) TNSN90061A1 (fr)
ZA (1) ZA903305B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5382579A (en) * 1988-10-31 1995-01-17 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5468740A (en) * 1988-10-31 1995-11-21 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
US5221671A (en) * 1988-10-31 1993-06-22 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5304553A (en) * 1988-10-31 1994-04-19 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
AT394563B (de) * 1990-05-09 1992-05-11 Scras Verfahren zur herstellung von thieno-triazolodiazepinderivaten
GB9207645D0 (en) * 1992-04-08 1992-05-27 Smithkline Beecham Corp Methods
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
US6987105B2 (en) * 2000-04-28 2006-01-17 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis and use of thienotriazolodiazepines
KR20110117731A (ko) 2003-05-30 2011-10-27 랜박시 래보러터리스 리미티드 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도
AU2006313430B2 (en) 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
DE3724031A1 (de) * 1986-07-22 1988-01-28 Boehringer Ingelheim Kg Neue hetrazepine und verfahren zu ihrer herstellung
WO1988009792A1 (fr) * 1987-06-08 1988-12-15 Yoshitomi Pharmaceutical Industries, Ltd. Composes de thienotriazolodiazepine a substitution ether et leur utilisation en medecine

Also Published As

Publication number Publication date
FI93119B (fi) 1994-11-15
SE9001670L (fr)
NO901813L (no) 1990-11-14
US5049559A (en) 1991-09-17
DE4015137A1 (de) 1990-11-15
IT9020276A0 (it) 1990-05-11
DK102990A (da) 1990-11-14
NZ233574A (en) 1991-07-26
SG91992G (en) 1992-12-04
FR2646851A1 (fr) 1990-11-16
LU87733A1 (fr) 1990-09-19
DE4015137C2 (de) 2003-06-12
GB9010403D0 (en) 1990-06-27
NO901813D0 (no) 1990-04-24
JPH035484A (ja) 1991-01-11
IE65246B1 (en) 1995-10-04
GB2231330B (en) 1992-04-29
SE505407C2 (sv) 1997-08-25
FI902355A0 (fi) 1990-05-11
IT9020276A1 (it) 1991-11-11
GB2231330A (en) 1990-11-14
AR245725A1 (es) 1994-02-28
IE901583L (en) 1990-11-13
FI93119C (fi) 1995-02-27
HK94992A (en) 1992-12-04
DK102990D0 (da) 1990-04-26
CA2016551C (fr) 1997-09-09
OA09209A (fr) 1992-06-30
SE9001670D0 (sv) 1990-05-09
BE1004122A3 (fr) 1992-09-29
NL9001089A (nl) 1990-12-03
CA2016551A1 (fr) 1990-11-13
NO173607B (no) 1993-09-27
IN174000B (fr) 1994-08-20
CH681009A5 (en) 1992-12-31
GB8911030D0 (en) 1989-06-28
PT94008B (pt) 1996-12-31
ES2019840A6 (es) 1991-07-01
MA21842A1 (fr) 1990-12-31
PT94008A (pt) 1991-01-08
DZ1414A1 (fr) 2004-09-13
TNSN90061A1 (fr) 1991-03-05
GR900100319A (en) 1991-10-10
ATA95690A (de) 1994-08-15
AU628171B2 (en) 1992-09-10
GR1000295B (el) 1992-05-12
FR2646774B1 (fr) 1992-02-14
AT399153B (de) 1995-03-27
JPH06104668B2 (ja) 1994-12-21
FR2646774A1 (fr) 1990-11-16
KR900018113A (ko) 1990-12-20
ZA903305B (en) 1991-02-27
IT1240935B (it) 1993-12-27
AU5493190A (en) 1990-11-15
NO173607C (no) 1994-01-05

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20100129