JPH0573754B2 - - Google Patents

Info

Publication number
JPH0573754B2
JPH0573754B2 JP59106330A JP10633084A JPH0573754B2 JP H0573754 B2 JPH0573754 B2 JP H0573754B2 JP 59106330 A JP59106330 A JP 59106330A JP 10633084 A JP10633084 A JP 10633084A JP H0573754 B2 JPH0573754 B2 JP H0573754B2
Authority
JP
Japan
Prior art keywords
compounds
spiro
oxindole
sodium
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59106330A
Other languages
English (en)
Japanese (ja)
Other versions
JPS604183A (ja
Inventor
Jefurii Hatsuchison Aran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Original Assignee
Pfizer Corp Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium filed Critical Pfizer Corp Belgium
Publication of JPS604183A publication Critical patent/JPS604183A/ja
Publication of JPH0573754B2 publication Critical patent/JPH0573754B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • External Artificial Organs (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
JP59106330A 1983-05-25 1984-05-25 イミダゾリジンジオン誘導体 Granted JPS604183A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US497962 1983-05-25
US06/497,962 US4464380A (en) 1983-05-25 1983-05-25 Imidazolidinedione derivatives

Publications (2)

Publication Number Publication Date
JPS604183A JPS604183A (ja) 1985-01-10
JPH0573754B2 true JPH0573754B2 (OSRAM) 1993-10-15

Family

ID=23979057

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59106330A Granted JPS604183A (ja) 1983-05-25 1984-05-25 イミダゾリジンジオン誘導体

Country Status (19)

Country Link
US (1) US4464380A (OSRAM)
EP (1) EP0127412B1 (OSRAM)
JP (1) JPS604183A (OSRAM)
KR (1) KR860001869B1 (OSRAM)
AT (1) ATE57531T1 (OSRAM)
AU (1) AU543916B2 (OSRAM)
CA (1) CA1266270A (OSRAM)
DE (1) DE3483402D1 (OSRAM)
DK (1) DK163924C (OSRAM)
ES (2) ES532736A0 (OSRAM)
FI (1) FI78699C (OSRAM)
GR (1) GR82020B (OSRAM)
HU (1) HU190548B (OSRAM)
IE (1) IE57520B1 (OSRAM)
IL (1) IL71904A (OSRAM)
PH (1) PH21151A (OSRAM)
PL (3) PL143290B1 (OSRAM)
PT (1) PT78625A (OSRAM)
YU (2) YU43931B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3565105D1 (en) * 1984-08-20 1988-10-27 Pfizer Process for the production as asymmetric hydantoins
US4762839A (en) * 1985-06-06 1988-08-09 Tanabe Seiyaku Co., Ltd. Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
JPS63132889A (ja) * 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
DK0769497T3 (da) * 1995-10-18 2003-04-07 Hoffmann La Roche Hydroxymethylering af tocopheroler
DK1144411T3 (da) 1998-12-19 2005-09-19 Janssen Pharmaceutica Nv Antihistaminspiroforbindelser
US20090076049A1 (en) * 2006-02-07 2009-03-19 Astrazeneca Ab Novel Spiro [Imidazolidine-4, 3' -Indole] 2, 2', 5' (1H) Triones for Treatment of Conditions Associated with Vanilloid Receptor 1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
ZA806623B (en) * 1979-11-13 1981-12-30 Ici Ltd Substituted indoline-2-one derivatives
IE50332B1 (en) * 1979-11-13 1986-04-02 Ici Ltd 1'-substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones,processes for their manufacture and pharmaceutical compositions thereof
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) * 1981-05-12 1988-03-30 Ici Plc Pharmaceutical spiro-hydantoin derivatives

Also Published As

Publication number Publication date
ES8600764A1 (es) 1985-10-16
AU2856384A (en) 1984-11-29
IE841294L (en) 1984-11-25
CA1266270A (en) 1990-02-27
JPS604183A (ja) 1985-01-10
DE3483402D1 (de) 1990-11-22
ES8607304A1 (es) 1986-06-01
FI78699B (fi) 1989-05-31
FI78699C (fi) 1989-09-11
GR82020B (OSRAM) 1984-12-12
EP0127412A2 (en) 1984-12-05
YU212286A (en) 1987-10-31
YU43931B (en) 1989-12-31
ES540858A0 (es) 1986-06-01
DK163924B (da) 1992-04-21
DK250084D0 (da) 1984-05-22
IL71904A (en) 1988-01-31
PL143290B1 (en) 1988-02-29
DK250084A (da) 1984-11-26
KR860001869B1 (ko) 1986-10-24
HUT34194A (en) 1985-02-28
KR840009101A (ko) 1984-12-24
ES532736A0 (es) 1985-10-16
EP0127412A3 (en) 1987-09-02
FI842079A0 (fi) 1984-05-24
YU89784A (en) 1987-04-30
DK163924C (da) 1992-09-14
AU543916B2 (en) 1985-05-09
PL247804A1 (en) 1985-08-13
IL71904A0 (en) 1984-09-30
PH21151A (en) 1987-07-30
YU43958B (en) 1989-12-31
FI842079A7 (fi) 1984-11-26
US4464380A (en) 1984-08-07
EP0127412B1 (en) 1990-10-17
HU190548B (en) 1986-09-29
PT78625A (en) 1984-06-01
PL143070B1 (en) 1988-01-30
ATE57531T1 (de) 1990-11-15
PL252850A1 (en) 1985-11-19
IE57520B1 (en) 1993-05-19

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