DE3483402D1 - Imidazolidinedion-derivate. - Google Patents

Imidazolidinedion-derivate.

Info

Publication number
DE3483402D1
DE3483402D1 DE8484303420T DE3483402T DE3483402D1 DE 3483402 D1 DE3483402 D1 DE 3483402D1 DE 8484303420 T DE8484303420 T DE 8484303420T DE 3483402 T DE3483402 T DE 3483402T DE 3483402 D1 DE3483402 D1 DE 3483402D1
Authority
DE
Germany
Prior art keywords
spiro
trione
imidazolidine
indoline
pyridylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484303420T
Other languages
English (en)
Inventor
Alan Jeffrey Hutchison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3483402D1 publication Critical patent/DE3483402D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8484303420T 1983-05-25 1984-05-21 Imidazolidinedion-derivate. Expired - Fee Related DE3483402D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/497,962 US4464380A (en) 1983-05-25 1983-05-25 Imidazolidinedione derivatives

Publications (1)

Publication Number Publication Date
DE3483402D1 true DE3483402D1 (de) 1990-11-22

Family

ID=23979057

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484303420T Expired - Fee Related DE3483402D1 (de) 1983-05-25 1984-05-21 Imidazolidinedion-derivate.

Country Status (19)

Country Link
US (1) US4464380A (de)
EP (1) EP0127412B1 (de)
JP (1) JPS604183A (de)
KR (1) KR860001869B1 (de)
AT (1) ATE57531T1 (de)
AU (1) AU543916B2 (de)
CA (1) CA1266270A (de)
DE (1) DE3483402D1 (de)
DK (1) DK163924C (de)
ES (2) ES8600764A1 (de)
FI (1) FI78699C (de)
GR (1) GR82020B (de)
HU (1) HU190548B (de)
IE (1) IE57520B1 (de)
IL (1) IL71904A (de)
PH (1) PH21151A (de)
PL (3) PL143070B1 (de)
PT (1) PT78625A (de)
YU (2) YU43931B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172719B1 (de) * 1984-08-20 1988-09-21 Pfizer Inc. Verfahren zur Herstellung asymmetrischer Hydantoine
US4762839A (en) * 1985-06-06 1988-08-09 Tanabe Seiyaku Co., Ltd. Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
JPS63132889A (ja) * 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
ATE229948T1 (de) * 1995-10-18 2003-01-15 Hoffmann La Roche Hydroxymethylierung von tocopherolen
US7148214B1 (en) 1998-12-19 2006-12-12 Janssen Pharmaceutica, N.V. Antihistaminic spiro compounds
JP2009526044A (ja) * 2006-02-07 2009-07-16 アストラゼネカ・アクチエボラーグ 新規な化合物ｉ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
AU532110B2 (en) * 1979-11-13 1983-09-15 Ici Ltd. Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives
ZA806623B (en) * 1979-11-13 1981-12-30 Ici Ltd Substituted indoline-2-one derivatives
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) * 1981-05-12 1988-03-30 Ici Plc Pharmaceutical spiro-hydantoin derivatives

Also Published As

Publication number Publication date
DK250084D0 (da) 1984-05-22
DK163924C (da) 1992-09-14
CA1266270A (en) 1990-02-27
YU89784A (en) 1987-04-30
PL143290B1 (en) 1988-02-29
ES8607304A1 (es) 1986-06-01
IE841294L (en) 1984-11-25
ES540858A0 (es) 1986-06-01
IE57520B1 (en) 1993-05-19
DK163924B (da) 1992-04-21
IL71904A (en) 1988-01-31
FI842079A (fi) 1984-11-26
GR82020B (de) 1984-12-12
AU543916B2 (en) 1985-05-09
ATE57531T1 (de) 1990-11-15
PT78625A (en) 1984-06-01
YU43931B (en) 1989-12-31
US4464380A (en) 1984-08-07
JPH0573754B2 (de) 1993-10-15
ES532736A0 (es) 1985-10-16
FI78699B (fi) 1989-05-31
HUT34194A (en) 1985-02-28
PL252850A1 (en) 1985-11-19
YU43958B (en) 1989-12-31
IL71904A0 (en) 1984-09-30
DK250084A (da) 1984-11-26
HU190548B (en) 1986-09-29
EP0127412A3 (en) 1987-09-02
PL247804A1 (en) 1985-08-13
KR840009101A (ko) 1984-12-24
EP0127412B1 (de) 1990-10-17
PL143070B1 (en) 1988-01-30
KR860001869B1 (ko) 1986-10-24
JPS604183A (ja) 1985-01-10
YU212286A (en) 1987-10-31
AU2856384A (en) 1984-11-29
EP0127412A2 (de) 1984-12-05
PH21151A (en) 1987-07-30
FI78699C (fi) 1989-09-11
ES8600764A1 (es) 1985-10-16
FI842079A0 (fi) 1984-05-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee