ATE57531T1 - Imidazolidinedion-derivate. - Google Patents

Imidazolidinedion-derivate.

Info

Publication number
ATE57531T1
ATE57531T1 AT84303420T AT84303420T ATE57531T1 AT E57531 T1 ATE57531 T1 AT E57531T1 AT 84303420 T AT84303420 T AT 84303420T AT 84303420 T AT84303420 T AT 84303420T AT E57531 T1 ATE57531 T1 AT E57531T1
Authority
AT
Austria
Prior art keywords
spiro
trione
imidazolidine
indoline
pyridylmethyl
Prior art date
Application number
AT84303420T
Other languages
English (en)
Inventor
Alan Jeffrey Hutchison
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE57531T1 publication Critical patent/ATE57531T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT84303420T 1983-05-25 1984-05-21 Imidazolidinedion-derivate. ATE57531T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/497,962 US4464380A (en) 1983-05-25 1983-05-25 Imidazolidinedione derivatives
EP84303420A EP0127412B1 (de) 1983-05-25 1984-05-21 Imidazolidinedion-Derivate

Publications (1)

Publication Number Publication Date
ATE57531T1 true ATE57531T1 (de) 1990-11-15

Family

ID=23979057

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84303420T ATE57531T1 (de) 1983-05-25 1984-05-21 Imidazolidinedion-derivate.

Country Status (19)

Country Link
US (1) US4464380A (de)
EP (1) EP0127412B1 (de)
JP (1) JPS604183A (de)
KR (1) KR860001869B1 (de)
AT (1) ATE57531T1 (de)
AU (1) AU543916B2 (de)
CA (1) CA1266270A (de)
DE (1) DE3483402D1 (de)
DK (1) DK163924C (de)
ES (2) ES532736A0 (de)
FI (1) FI78699C (de)
GR (1) GR82020B (de)
HU (1) HU190548B (de)
IE (1) IE57520B1 (de)
IL (1) IL71904A (de)
PH (1) PH21151A (de)
PL (3) PL143070B1 (de)
PT (1) PT78625A (de)
YU (2) YU43931B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE37371T1 (de) * 1984-08-20 1988-10-15 Pfizer Verfahren zur herstellung asymmetrischer hydantoine.
US4762839A (en) * 1985-06-06 1988-08-09 Tanabe Seiyaku Co., Ltd. Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
JPS63132889A (ja) * 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
ATE229948T1 (de) * 1995-10-18 2003-01-15 Hoffmann La Roche Hydroxymethylierung von tocopherolen
BR9916371A (pt) 1998-12-19 2001-09-18 Janssen Pharmaceutica Nv Composto de espiro anti-histamìnico
EP2013216A2 (de) * 2006-02-07 2009-01-14 AstraZeneca AB Neue spiro[imidazolidin-4,3'-indol]-2,2',5'(1h)-trione zur behandlung von mit dem vanilloidrezeptor 1 assoziierten leiden

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
ZA806623B (en) * 1979-11-13 1981-12-30 Ici Ltd Substituted indoline-2-one derivatives
AU532110B2 (en) * 1979-11-13 1983-09-15 Ici Ltd. Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) * 1981-05-12 1988-03-30 Ici Plc Pharmaceutical spiro-hydantoin derivatives

Also Published As

Publication number Publication date
HU190548B (en) 1986-09-29
DK250084D0 (da) 1984-05-22
ES540858A0 (es) 1986-06-01
FI78699C (fi) 1989-09-11
JPH0573754B2 (de) 1993-10-15
PL143070B1 (en) 1988-01-30
IL71904A0 (en) 1984-09-30
IE57520B1 (en) 1993-05-19
EP0127412A2 (de) 1984-12-05
ES8600764A1 (es) 1985-10-16
FI842079A (fi) 1984-11-26
US4464380A (en) 1984-08-07
AU543916B2 (en) 1985-05-09
GR82020B (de) 1984-12-12
ES532736A0 (es) 1985-10-16
YU89784A (en) 1987-04-30
EP0127412A3 (en) 1987-09-02
CA1266270A (en) 1990-02-27
DK163924C (da) 1992-09-14
PL252850A1 (en) 1985-11-19
DK250084A (da) 1984-11-26
YU43931B (en) 1989-12-31
YU43958B (en) 1989-12-31
PL247804A1 (en) 1985-08-13
FI78699B (fi) 1989-05-31
KR840009101A (ko) 1984-12-24
HUT34194A (en) 1985-02-28
YU212286A (en) 1987-10-31
PL143290B1 (en) 1988-02-29
EP0127412B1 (de) 1990-10-17
IL71904A (en) 1988-01-31
FI842079A0 (fi) 1984-05-24
AU2856384A (en) 1984-11-29
ES8607304A1 (es) 1986-06-01
KR860001869B1 (ko) 1986-10-24
JPS604183A (ja) 1985-01-10
IE841294L (en) 1984-11-25
PH21151A (en) 1987-07-30
PT78625A (en) 1984-06-01
DE3483402D1 (de) 1990-11-22
DK163924B (da) 1992-04-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee