GR82020B - - Google Patents

Info

Publication number
GR82020B
GR82020B GR74816A GR840174816A GR82020B GR 82020 B GR82020 B GR 82020B GR 74816 A GR74816 A GR 74816A GR 840174816 A GR840174816 A GR 840174816A GR 82020 B GR82020 B GR 82020B
Authority
GR
Greece
Prior art keywords
spiro
trione
imidazolidine
indoline
pyridylmethyl
Prior art date
Application number
GR74816A
Other languages
English (en)
Inventor
Alan Jeffrey Hutchison
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR82020B publication Critical patent/GR82020B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
GR74816A 1983-05-25 1984-05-24 GR82020B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/497,962 US4464380A (en) 1983-05-25 1983-05-25 Imidazolidinedione derivatives

Publications (1)

Publication Number Publication Date
GR82020B true GR82020B (el) 1984-12-12

Family

ID=23979057

Family Applications (1)

Application Number Title Priority Date Filing Date
GR74816A GR82020B (el) 1983-05-25 1984-05-24

Country Status (19)

Country Link
US (1) US4464380A (el)
EP (1) EP0127412B1 (el)
JP (1) JPS604183A (el)
KR (1) KR860001869B1 (el)
AT (1) ATE57531T1 (el)
AU (1) AU543916B2 (el)
CA (1) CA1266270A (el)
DE (1) DE3483402D1 (el)
DK (1) DK163924C (el)
ES (2) ES532736A0 (el)
FI (1) FI78699C (el)
GR (1) GR82020B (el)
HU (1) HU190548B (el)
IE (1) IE57520B1 (el)
IL (1) IL71904A (el)
PH (1) PH21151A (el)
PL (3) PL252850A1 (el)
PT (1) PT78625A (el)
YU (2) YU43931B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE37371T1 (de) * 1984-08-20 1988-10-15 Pfizer Verfahren zur herstellung asymmetrischer hydantoine.
US4762839A (en) * 1985-06-06 1988-08-09 Tanabe Seiyaku Co., Ltd. Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
JPS63132889A (ja) * 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
DE59609995D1 (de) * 1995-10-18 2003-01-30 Hoffmann La Roche Hydroxymethylierung von Tocopherolen
PT1144411E (pt) 1998-12-19 2005-09-30 Janssen Pharmaceutica Nv Compostos espiro anti-histaminicos
US20090076049A1 (en) * 2006-02-07 2009-03-19 Astrazeneca Ab Novel Spiro [Imidazolidine-4, 3' -Indole] 2, 2', 5' (1H) Triones for Treatment of Conditions Associated with Vanilloid Receptor 1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
ZA806623B (en) * 1979-11-13 1981-12-30 Ici Ltd Substituted indoline-2-one derivatives
US4490381A (en) * 1979-11-13 1984-12-25 Imperial Chemical Industries Plc 1'-Substituted spiro[imidazolidine-4,3'-indoline]2,2',5-triones
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) * 1981-05-12 1988-03-30 Ici Plc Pharmaceutical spiro-hydantoin derivatives

Also Published As

Publication number Publication date
PL143290B1 (en) 1988-02-29
JPH0573754B2 (el) 1993-10-15
ATE57531T1 (de) 1990-11-15
AU2856384A (en) 1984-11-29
CA1266270A (en) 1990-02-27
FI78699C (fi) 1989-09-11
YU212286A (en) 1987-10-31
EP0127412A3 (en) 1987-09-02
IL71904A0 (en) 1984-09-30
PT78625A (en) 1984-06-01
DE3483402D1 (de) 1990-11-22
DK163924B (da) 1992-04-21
KR860001869B1 (ko) 1986-10-24
HU190548B (en) 1986-09-29
FI842079A (fi) 1984-11-26
HUT34194A (en) 1985-02-28
PH21151A (en) 1987-07-30
IE57520B1 (en) 1993-05-19
PL247804A1 (en) 1985-08-13
ES540858A0 (es) 1986-06-01
AU543916B2 (en) 1985-05-09
ES8607304A1 (es) 1986-06-01
DK250084D0 (da) 1984-05-22
US4464380A (en) 1984-08-07
JPS604183A (ja) 1985-01-10
ES8600764A1 (es) 1985-10-16
KR840009101A (ko) 1984-12-24
FI78699B (fi) 1989-05-31
ES532736A0 (es) 1985-10-16
YU43931B (en) 1989-12-31
EP0127412B1 (en) 1990-10-17
DK250084A (da) 1984-11-26
PL143070B1 (en) 1988-01-30
IL71904A (en) 1988-01-31
IE841294L (en) 1984-11-25
YU43958B (en) 1989-12-31
YU89784A (en) 1987-04-30
FI842079A0 (fi) 1984-05-24
PL252850A1 (en) 1985-11-19
DK163924C (da) 1992-09-14
EP0127412A2 (en) 1984-12-05

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