ES8600764A1 - Un procedimiento para la preparacion de derivados de espiro-hidantoina - Google Patents
Un procedimiento para la preparacion de derivados de espiro-hidantoinaInfo
- Publication number
- ES8600764A1 ES8600764A1 ES532736A ES532736A ES8600764A1 ES 8600764 A1 ES8600764 A1 ES 8600764A1 ES 532736 A ES532736 A ES 532736A ES 532736 A ES532736 A ES 532736A ES 8600764 A1 ES8600764 A1 ES 8600764A1
- Authority
- ES
- Spain
- Prior art keywords
- fch
- formulas
- reaction
- chfn
- nfch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001468 imidazolidinediones Chemical class 0.000 title 1
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 abstract 1
- -1 CARBONYL CYCLIC COMPOUND Chemical class 0.000 abstract 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
- 235000012501 ammonium carbonate Nutrition 0.000 abstract 1
- 239000001099 ammonium carbonate Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- External Artificial Organs (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/497,962 US4464380A (en) | 1983-05-25 | 1983-05-25 | Imidazolidinedione derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8600764A1 true ES8600764A1 (es) | 1985-10-16 |
| ES532736A0 ES532736A0 (es) | 1985-10-16 |
Family
ID=23979057
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES532736A Granted ES532736A0 (es) | 1983-05-25 | 1984-05-23 | Un procedimiento para la preparacion de derivados de espiro-hidantoina |
| ES540858A Expired ES8607304A1 (es) | 1983-05-25 | 1985-03-01 | Un procedimiento para la preparacion de derivados de espiro-hidantoina |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES540858A Expired ES8607304A1 (es) | 1983-05-25 | 1985-03-01 | Un procedimiento para la preparacion de derivados de espiro-hidantoina |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4464380A (OSRAM) |
| EP (1) | EP0127412B1 (OSRAM) |
| JP (1) | JPS604183A (OSRAM) |
| KR (1) | KR860001869B1 (OSRAM) |
| AT (1) | ATE57531T1 (OSRAM) |
| AU (1) | AU543916B2 (OSRAM) |
| CA (1) | CA1266270A (OSRAM) |
| DE (1) | DE3483402D1 (OSRAM) |
| DK (1) | DK163924C (OSRAM) |
| ES (2) | ES532736A0 (OSRAM) |
| FI (1) | FI78699C (OSRAM) |
| GR (1) | GR82020B (OSRAM) |
| HU (1) | HU190548B (OSRAM) |
| IE (1) | IE57520B1 (OSRAM) |
| IL (1) | IL71904A (OSRAM) |
| PH (1) | PH21151A (OSRAM) |
| PL (3) | PL143290B1 (OSRAM) |
| PT (1) | PT78625A (OSRAM) |
| YU (2) | YU43931B (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3565105D1 (en) * | 1984-08-20 | 1988-10-27 | Pfizer | Process for the production as asymmetric hydantoins |
| US4762839A (en) * | 1985-06-06 | 1988-08-09 | Tanabe Seiyaku Co., Ltd. | Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications |
| JPS63132889A (ja) * | 1986-11-21 | 1988-06-04 | Tanabe Seiyaku Co Ltd | キナゾリノン誘導体 |
| US4841079A (en) * | 1987-08-07 | 1989-06-20 | Pfizer, Inc. | Process for the production of asymmetric hydantoins |
| DK0769497T3 (da) * | 1995-10-18 | 2003-04-07 | Hoffmann La Roche | Hydroxymethylering af tocopheroler |
| DK1144411T3 (da) | 1998-12-19 | 2005-09-19 | Janssen Pharmaceutica Nv | Antihistaminspiroforbindelser |
| US20090076049A1 (en) * | 2006-02-07 | 2009-03-19 | Astrazeneca Ab | Novel Spiro [Imidazolidine-4, 3' -Indole] 2, 2', 5' (1H) Triones for Treatment of Conditions Associated with Vanilloid Receptor 1 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
| US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
| ZA806623B (en) * | 1979-11-13 | 1981-12-30 | Ici Ltd | Substituted indoline-2-one derivatives |
| IE50332B1 (en) * | 1979-11-13 | 1986-04-02 | Ici Ltd | 1'-substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones,processes for their manufacture and pharmaceutical compositions thereof |
| US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
| IE52879B1 (en) * | 1981-05-12 | 1988-03-30 | Ici Plc | Pharmaceutical spiro-hydantoin derivatives |
-
1983
- 1983-05-25 US US06/497,962 patent/US4464380A/en not_active Expired - Fee Related
-
1984
- 1984-05-21 PT PT78625A patent/PT78625A/pt not_active IP Right Cessation
- 1984-05-21 DE DE8484303420T patent/DE3483402D1/de not_active Expired - Lifetime
- 1984-05-21 EP EP84303420A patent/EP0127412B1/en not_active Expired - Lifetime
- 1984-05-21 AT AT84303420T patent/ATE57531T1/de not_active IP Right Cessation
- 1984-05-22 DK DK250084A patent/DK163924C/da not_active IP Right Cessation
- 1984-05-23 PH PH30711A patent/PH21151A/en unknown
- 1984-05-23 PL PL1984247804A patent/PL143290B1/pl unknown
- 1984-05-23 CA CA000454883A patent/CA1266270A/en not_active Expired - Lifetime
- 1984-05-23 PL PL1984242850A patent/PL143070B1/pl unknown
- 1984-05-23 ES ES532736A patent/ES532736A0/es active Granted
- 1984-05-23 YU YU897/84A patent/YU43931B/xx unknown
- 1984-05-23 PL PL25285084A patent/PL252850A1/xx unknown
- 1984-05-23 IL IL71904A patent/IL71904A/xx unknown
- 1984-05-24 AU AU28563/84A patent/AU543916B2/en not_active Ceased
- 1984-05-24 HU HU842021A patent/HU190548B/hu not_active IP Right Cessation
- 1984-05-24 IE IE1294/84A patent/IE57520B1/en not_active IP Right Cessation
- 1984-05-24 FI FI842079A patent/FI78699C/fi not_active IP Right Cessation
- 1984-05-24 GR GR74816A patent/GR82020B/el unknown
- 1984-05-24 KR KR1019840002843A patent/KR860001869B1/ko not_active Expired
- 1984-05-25 JP JP59106330A patent/JPS604183A/ja active Granted
-
1985
- 1985-03-01 ES ES540858A patent/ES8607304A1/es not_active Expired
-
1986
- 1986-12-11 YU YU2122/86A patent/YU43958B/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |