JPH053851B2 - - Google Patents
Info
- Publication number
- JPH053851B2 JPH053851B2 JP60068512A JP6851285A JPH053851B2 JP H053851 B2 JPH053851 B2 JP H053851B2 JP 60068512 A JP60068512 A JP 60068512A JP 6851285 A JP6851285 A JP 6851285A JP H053851 B2 JPH053851 B2 JP H053851B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- isoquinolinesulfonyl
- acid
- homopiperazine
- methylhomopiperazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6851285A JPS61227581A (ja) | 1985-04-02 | 1985-04-02 | 血管拡張剤 |
DE8585116520T DE3583287D1 (de) | 1984-12-27 | 1985-12-23 | Substituierte isochinolinsulfonyl-verbindungen. |
EP19850116520 EP0187371B1 (en) | 1984-12-27 | 1985-12-23 | Substituted isoquinolinesulfonyl compounds |
AT85116520T ATE64598T1 (de) | 1984-12-27 | 1985-12-23 | Substituierte isochinolinsulfonyl-verbindungen. |
US06813973 US4678783B1 (en) | 1983-11-04 | 1985-12-27 | Substituted isoquinolinesulfonyl compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6851285A JPS61227581A (ja) | 1985-04-02 | 1985-04-02 | 血管拡張剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS61227581A JPS61227581A (ja) | 1986-10-09 |
JPH053851B2 true JPH053851B2 (enrdf_load_stackoverflow) | 1993-01-18 |
Family
ID=13375841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6851285A Granted JPS61227581A (ja) | 1983-11-04 | 1985-04-02 | 血管拡張剤 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS61227581A (enrdf_load_stackoverflow) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0667926B2 (ja) * | 1985-11-12 | 1994-08-31 | 旭化成工業株式会社 | 環状のイソキノリンスルホンアミド誘導体 |
JP2720348B2 (ja) * | 1989-03-30 | 1998-03-04 | 旭化成工業株式会社 | 脳細胞機能障害改善剤 |
JP2893029B2 (ja) * | 1992-08-10 | 1999-05-17 | 旭化成工業株式会社 | 心臓保護剤 |
JPH0680569A (ja) * | 1992-09-03 | 1994-03-22 | Asahi Chem Ind Co Ltd | 血小板凝集阻害剤 |
AU1557497A (en) * | 1996-02-02 | 1997-08-22 | Nippon Shinyaku Co. Ltd. | Isoquinoline derivatives and drugs |
CZ301044B6 (cs) | 1996-08-12 | 2009-10-21 | Mitsubishi Tanabe Pharma | Léciva obsahující amidové deriváty inhibující Rho kinázu |
EP1074545A4 (en) * | 1998-04-23 | 2001-08-22 | Hiroyoshi Hidaka | ISOCHINOLINE SULPHONAMIDE DERIVATIVES AND MEDICINES CONTAINING IT AS AN ACTIVE INGREDIENT |
KR100396171B1 (ko) * | 1998-08-10 | 2003-08-27 | 아사히 가세이 가부시키가이샤 | 염산 파수딜의 경구 서방성 제제 |
JP4509395B2 (ja) | 1999-04-27 | 2010-07-21 | 田辺三菱製薬株式会社 | 肝臓疾患の予防治療薬 |
JP4582561B2 (ja) * | 2000-10-23 | 2010-11-17 | 旭化成ファーマ株式会社 | 移植による血管病変の発生抑制剤 |
CA2555763A1 (en) * | 2004-01-29 | 2005-08-11 | Asahi Kasei Pharma Corporation | Therapeutic agent for vasospasm accompanying bypass operation |
US7718797B2 (en) | 2004-03-16 | 2010-05-18 | Asahi Kasei Pharma Corporation | Fasudil-containing preparation and method of improving stability thereof |
EP1878732B1 (en) | 2005-04-25 | 2009-02-25 | D. Western Therapeutics Institute | HIGHLY SELECTIVE Rho-KINASE INHIBITOR |
US8193193B2 (en) | 2005-07-12 | 2012-06-05 | Kowa Co., Ltd. | Agent for prevention or treatment of glaucoma |
JP5781727B2 (ja) | 2007-02-23 | 2015-09-24 | 株式会社ネクスト21 | 血管攣縮の治療剤又は予防剤 |
CN103068818B (zh) | 2010-08-26 | 2014-11-19 | 兴和株式会社 | 异喹啉衍生物或其盐的新制造方法 |
CN111132983B (zh) * | 2017-09-25 | 2022-05-17 | 华润医药控股有限公司 | 一种异喹啉磺酰衍生物的晶型及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0227992B2 (ja) * | 1982-01-14 | 1990-06-20 | Asahi Kasei Kogyo Kk | Isokinorinsuruhonirukagobutsu |
JPS57200366A (en) * | 1981-06-01 | 1982-12-08 | Asahi Chem Ind Co Ltd | Isoquinoline compound |
JPS5993054A (ja) * | 1982-11-18 | 1984-05-29 | Asahi Chem Ind Co Ltd | イソキノリンスルホン酸アミド誘導体 |
-
1985
- 1985-04-02 JP JP6851285A patent/JPS61227581A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS61227581A (ja) | 1986-10-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EXPY | Cancellation because of completion of term |