JP7584218B2 - Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 - Google Patents

Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 Download PDF

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JP7584218B2
JP7584218B2 JP2019511889A JP2019511889A JP7584218B2 JP 7584218 B2 JP7584218 B2 JP 7584218B2 JP 2019511889 A JP2019511889 A JP 2019511889A JP 2019511889 A JP2019511889 A JP 2019511889A JP 7584218 B2 JP7584218 B2 JP 7584218B2
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ジェニファー・ディー・ハミルトン
ブライアン・エヌ・スワンソン
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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JP2019511889A 2016-09-01 2017-08-31 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 Active JP7584218B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022134609A JP7542582B2 (ja) 2016-09-01 2022-08-26 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法
JP2024137494A JP2024164098A (ja) 2016-09-01 2024-08-19 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662382501P 2016-09-01 2016-09-01
US62/382,501 2016-09-01
US201662425726P 2016-11-23 2016-11-23
US62/425,726 2016-11-23
PCT/US2017/049538 WO2018045130A1 (en) 2016-09-01 2017-08-31 Methods for preventing or treating allergy by administering an il-4r antagonist

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JP2022134609A Division JP7542582B2 (ja) 2016-09-01 2022-08-26 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法

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JP2019531273A JP2019531273A (ja) 2019-10-31
JP2019531273A5 JP2019531273A5 (https=) 2020-10-01
JP7584218B2 true JP7584218B2 (ja) 2024-11-15

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JP2019511889A Active JP7584218B2 (ja) 2016-09-01 2017-08-31 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法
JP2022134609A Active JP7542582B2 (ja) 2016-09-01 2022-08-26 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法
JP2024137494A Pending JP2024164098A (ja) 2016-09-01 2024-08-19 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法

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JP2024137494A Pending JP2024164098A (ja) 2016-09-01 2024-08-19 Ｉｌ－４ｒアンタゴニストを投与することによりアレルギーを予防又は処置するための方法

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US (2) US11771743B2 (https=)
EP (2) EP4442323A3 (https=)
JP (3) JP7584218B2 (https=)
KR (3) KR20240065318A (https=)
CN (2) CN118141914A (https=)
CA (1) CA3035202A1 (https=)
ES (1) ES2994774T3 (https=)
HU (1) HUE067888T2 (https=)
IL (2) IL320424A (https=)
MA (1) MA46098B1 (https=)
MX (2) MX2019002344A (https=)
PL (1) PL3506931T3 (https=)
PT (1) PT3506931T (https=)
WO (1) WO2018045130A1 (https=)

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PL2892927T3 (pl) 2012-09-07 2018-11-30 Regeneron Pharmaceuticals, Inc. Sposoby leczenia atopowego zapalenia skóry przez podawanie antagonisty IL-4R
TWI755763B (zh) 2013-06-04 2022-02-21 美商再生元醫藥公司 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
TWI634900B (zh) 2013-07-11 2018-09-11 再生元醫藥公司 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法
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