JP7308034B2 - 最適化二重ヌクレアーゼ融合物および方法 - Google Patents

最適化二重ヌクレアーゼ融合物および方法 Download PDF

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JP7308034B2
JP7308034B2 JP2018569138A JP2018569138A JP7308034B2 JP 7308034 B2 JP7308034 B2 JP 7308034B2 JP 2018569138 A JP2018569138 A JP 2018569138A JP 2018569138 A JP2018569138 A JP 2018569138A JP 7308034 B2 JP7308034 B2 JP 7308034B2
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polypeptide
amino acid
domain
seq
acid sequence
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JP2019530430A (ja
JP2019530430A5 (enExample
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ジェイムズ アーサー ポサダ，
サンジェイ パテル，
ウェイホン ユー，
クリス ガベル，
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リゾルブ セラピューティクス， エルエルシー
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JP2018569138A 2016-07-01 2017-06-30 最適化二重ヌクレアーゼ融合物および方法 Active JP7308034B2 (ja)

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JP2022122570A JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

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US201662357756P 2016-07-01 2016-07-01
US62/357,756 2016-07-01
PCT/US2017/040267 WO2018005954A2 (en) 2016-07-01 2017-06-30 Optimized binuclease fusions and methods

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JP2023208402A Pending JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

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US (4) US20190241878A1 (enExample)
EP (2) EP3478830B1 (enExample)
JP (3) JP7308034B2 (enExample)
CN (2) CN119120423A (enExample)
AU (2) AU2017290389B2 (enExample)
CA (1) CA3029627A1 (enExample)
DK (1) DK3478830T3 (enExample)
HR (1) HRP20240603T1 (enExample)
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WO2011053982A2 (en) 2009-11-02 2011-05-05 University Of Washington Therapeutic nuclease compositions and methods
JP6063450B2 (ja) 2011-04-29 2017-01-18 ユニヴァーシティ オブ ワシントン 治療用ヌクレアーゼ組成物および方法
HRP20192080T1 (hr) 2013-10-31 2020-02-07 Resolve Therapeutics, Llc Terapeutske fuzije nukleaza-albumine i postupci
DK3478830T3 (da) 2016-07-01 2024-05-21 Resolve Therapeutics Llc Optimerede binucleasefusioner og metoder
JP7374091B2 (ja) 2017-08-22 2023-11-06 サナバイオ， エルエルシー 可溶性インターフェロン受容体およびその使用
KR20210113261A (ko) * 2019-01-04 2021-09-15 리졸브 테라퓨틱스, 엘엘씨 뉴클레아제 융합 단백질을 사용한 쇼그렌병의 치료
EP4090736A4 (en) * 2020-01-11 2024-02-21 Yale University COMPOSITIONS AND METHODS FOR THE TREATMENT, RELIEF AND/OR PREVENTION OF ILLNESSES OR DISORDERS ASSOCIATED WITH DNASE1 AND/OR DNASE1L3 DEFICIENCY
US20230226158A1 (en) * 2020-06-08 2023-07-20 Yale University Compositions and methods for treating and/or preventing coagulopathy and/or sepsis in patients suffering from bacterial and/or viral infections
CN112322607B (zh) * 2020-11-20 2023-03-28 江南大学 一种融合型腈水合酶及其应用
US12180521B2 (en) * 2021-02-19 2024-12-31 Theripion, Inc. Paraoxonase fusion polypeptides and related compositions and methods
WO2025147696A1 (en) * 2024-01-05 2025-07-10 Resolve Therapeutics, Llc Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
US12416020B2 (en) 2024-02-20 2025-09-16 Wyvern Pharmaceuticals Inc. Plasmid encoding a TLR3 and Fc fusion protein

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JP2014519809A (ja) 2011-04-29 2014-08-21 ユニヴァーシティ オブ ワシントン 治療用ヌクレアーゼ組成物および方法
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