JP2019530430A5 - - Google Patents

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JP2019530430A5
JP2019530430A5 JP2018569138A JP2018569138A JP2019530430A5 JP 2019530430 A5 JP2019530430 A5 JP 2019530430A5 JP 2018569138 A JP2018569138 A JP 2018569138A JP 2018569138 A JP2018569138 A JP 2018569138A JP 2019530430 A5 JP2019530430 A5 JP 2019530430A5
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domain
acid sequence
amino acid
heterodimer
linker
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JP2018569138A
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JP2019530430A (ja
JP7308034B2 (ja
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Priority claimed from PCT/US2017/040267 external-priority patent/WO2018005954A2/en
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Priority to JP2022122570A priority Critical patent/JP2022153588A/ja
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Publication of JP7308034B2 publication Critical patent/JP7308034B2/ja
Priority to JP2023208402A priority patent/JP2024026334A/ja
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JP2018569138A 2016-07-01 2017-06-30 最適化二重ヌクレアーゼ融合物および方法 Active JP7308034B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022122570A JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662357756P 2016-07-01 2016-07-01
US62/357,756 2016-07-01
PCT/US2017/040267 WO2018005954A2 (en) 2016-07-01 2017-06-30 Optimized binuclease fusions and methods

Related Child Applications (1)

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JP2022122570A Division JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法

Publications (3)

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JP2019530430A JP2019530430A (ja) 2019-10-24
JP2019530430A5 true JP2019530430A5 (enExample) 2020-08-06
JP7308034B2 JP7308034B2 (ja) 2023-07-13

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JP2018569138A Active JP7308034B2 (ja) 2016-07-01 2017-06-30 最適化二重ヌクレアーゼ融合物および方法
JP2022122570A Pending JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A Pending JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

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JP2022122570A Pending JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A Pending JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

Country Status (10)

Country Link
US (4) US20190241878A1 (enExample)
EP (2) EP3478830B1 (enExample)
JP (3) JP7308034B2 (enExample)
CN (2) CN119120423A (enExample)
AU (2) AU2017290389B2 (enExample)
CA (1) CA3029627A1 (enExample)
DK (1) DK3478830T3 (enExample)
HR (1) HRP20240603T1 (enExample)
MA (1) MA45554A (enExample)
WO (1) WO2018005954A2 (enExample)

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WO2011053982A2 (en) 2009-11-02 2011-05-05 University Of Washington Therapeutic nuclease compositions and methods
JP6063450B2 (ja) 2011-04-29 2017-01-18 ユニヴァーシティ オブ ワシントン 治療用ヌクレアーゼ組成物および方法
HRP20192080T1 (hr) 2013-10-31 2020-02-07 Resolve Therapeutics, Llc Terapeutske fuzije nukleaza-albumine i postupci
DK3478830T3 (da) 2016-07-01 2024-05-21 Resolve Therapeutics Llc Optimerede binucleasefusioner og metoder
JP7374091B2 (ja) 2017-08-22 2023-11-06 サナバイオ, エルエルシー 可溶性インターフェロン受容体およびその使用
KR20210113261A (ko) * 2019-01-04 2021-09-15 리졸브 테라퓨틱스, 엘엘씨 뉴클레아제 융합 단백질을 사용한 쇼그렌병의 치료
EP4090736A4 (en) * 2020-01-11 2024-02-21 Yale University COMPOSITIONS AND METHODS FOR THE TREATMENT, RELIEF AND/OR PREVENTION OF ILLNESSES OR DISORDERS ASSOCIATED WITH DNASE1 AND/OR DNASE1L3 DEFICIENCY
US20230226158A1 (en) * 2020-06-08 2023-07-20 Yale University Compositions and methods for treating and/or preventing coagulopathy and/or sepsis in patients suffering from bacterial and/or viral infections
CN112322607B (zh) * 2020-11-20 2023-03-28 江南大学 一种融合型腈水合酶及其应用
US12180521B2 (en) * 2021-02-19 2024-12-31 Theripion, Inc. Paraoxonase fusion polypeptides and related compositions and methods
WO2025147696A1 (en) * 2024-01-05 2025-07-10 Resolve Therapeutics, Llc Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
US12416020B2 (en) 2024-02-20 2025-09-16 Wyvern Pharmaceuticals Inc. Plasmid encoding a TLR3 and Fc fusion protein

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