JP7219218B2 - 新規のベンジルアミノ置換キナゾリンおよびｓｏｓ１阻害剤としての誘導体 - Google Patents

新規のベンジルアミノ置換キナゾリンおよびｓｏｓ１阻害剤としての誘導体 Download PDF

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JP7219218B2
JP7219218B2 JP2019534303A JP2019534303A JP7219218B2 JP 7219218 B2 JP7219218 B2 JP 7219218B2 JP 2019534303 A JP2019534303 A JP 2019534303A JP 2019534303 A JP2019534303 A JP 2019534303A JP 7219218 B2 JP7219218 B2 JP 7219218B2
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JP2020504742A (ja
JP2020504742A5 (enExample
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ミヒャエル グマッシュ
ミヒャエル サンダーソン
ディルク ケスラー
クリスティアーネ コフィンク
マシュー ラッセル ネザートン
ユルゲン ラムハーター
トビアス ヴンベルク
マルコ ホフマン
ファビオ サバリース
アンケ バウム
ドロテーア ルドルフ
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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JP2019534303A 2016-12-22 2017-12-21 新規のベンジルアミノ置換キナゾリンおよびｓｏｓ１阻害剤としての誘導体 Active JP7219218B2 (ja)

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EP16206422 2016-12-22
EP16206422.4 2016-12-22
PCT/EP2017/084265 WO2018115380A1 (en) 2016-12-22 2017-12-21 Novel benzylamino substituted quinazolines and derivatives as sos1 inhibitors

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JP2020504742A5 JP2020504742A5 (enExample) 2021-02-04
JP7219218B2 true JP7219218B2 (ja) 2023-02-07

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US (2) US10898487B2 (enExample)
EP (2) EP3878850A1 (enExample)
JP (1) JP7219218B2 (enExample)
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WO (1) WO2018115380A1 (enExample)

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EP3458445B1 (en) 2016-05-18 2021-02-17 Mirati Therapeutics, Inc. Kras g12c inhibitors
EP3878850A1 (en) * 2016-12-22 2021-09-15 Boehringer Ingelheim International GmbH Novel benzylamino substituted quinazolines and derivatives as sos1 inhibitors
WO2018126192A1 (en) * 2016-12-30 2018-07-05 Children's Medical Center Corporation Map2k1 (mek1) as a therapeutic target for arteriovenous malformations and associated disorders
EP3601267A1 (en) * 2017-03-21 2020-02-05 Bayer Pharma Aktiengesellschaft 2-methyl-quinazolines
EP3710439B1 (en) 2017-11-15 2023-02-15 Mirati Therapeutics, Inc. Kras g12c inhibitors
US10647715B2 (en) 2017-11-15 2020-05-12 Mirati Therapeutics, Inc. KRas G12C inhibitors
LT3728254T (lt) 2017-12-21 2023-05-10 Boehringer Ingelheim International Gmbh Naujieji benzilaminu pakeistieji piridopirimidinonai ir jų dariniai kaip sos1 inhibitoriai
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