JP7118642B2 - 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物 - Google Patents

炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物 Download PDF

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JP7118642B2
JP7118642B2 JP2017508099A JP2017508099A JP7118642B2 JP 7118642 B2 JP7118642 B2 JP 7118642B2 JP 2017508099 A JP2017508099 A JP 2017508099A JP 2017508099 A JP2017508099 A JP 2017508099A JP 7118642 B2 JP7118642 B2 JP 7118642B2
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acid
mixture
composition
palmitoylethanolamide
fatty acids
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JP2017523230A5 (enExample
JP2017523230A (ja
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ミリアッチョ ラッファエーレ
サルディ アントネッラ
ミリアッチョ カルメーラ
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アリ リサーチ ソシエタ ア レスポンサビリタ リミタータ センプリフィカタ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2017508099A 2014-08-08 2015-08-03 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物 Active JP7118642B2 (ja)

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JP2020172613A JP7335475B2 (ja) 2014-08-08 2020-10-13 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物
JP2023012916A JP2023041806A (ja) 2014-08-08 2023-01-31 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物

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ITMI2014A001474 2014-08-08
ITMI20141474 2014-08-08
PCT/IB2015/055885 WO2016020828A1 (en) 2014-08-08 2015-08-03 Mixture of fatty acids and palmitoylethanolamide for use in the treatment of inflammatory and allergic pathologies

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JP2020172613A Division JP7335475B2 (ja) 2014-08-08 2020-10-13 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物

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JP2017523230A JP2017523230A (ja) 2017-08-17
JP2017523230A5 JP2017523230A5 (enExample) 2018-05-17
JP7118642B2 true JP7118642B2 (ja) 2022-08-16

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JP2017508099A Active JP7118642B2 (ja) 2014-08-08 2015-08-03 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物
JP2020172613A Active JP7335475B2 (ja) 2014-08-08 2020-10-13 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物
JP2023012916A Ceased JP2023041806A (ja) 2014-08-08 2023-01-31 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物

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JP2023012916A Ceased JP2023041806A (ja) 2014-08-08 2023-01-31 炎症性およびアレルギー性病変の治療に用いるための脂肪酸とパルミトイルエタノールアミドの混合物

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US (2) US9962355B2 (enExample)
EP (1) EP3177281B1 (enExample)
JP (3) JP7118642B2 (enExample)
CN (1) CN106714792A (enExample)
CA (1) CA2957700C (enExample)
CO (1) CO2017001088A2 (enExample)
DK (1) DK3177281T3 (enExample)
ES (1) ES2976095T3 (enExample)
FI (1) FI3177281T3 (enExample)
IL (1) IL250271B2 (enExample)
MA (1) MA40417A (enExample)
TW (1) TWI727926B (enExample)
WO (1) WO2016020828A1 (enExample)

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AU2016334086B2 (en) * 2015-10-07 2022-10-20 Cormedix Inc. Skin-penetrating formulation of taurolidine
CN109893520A (zh) * 2019-03-21 2019-06-18 中国科学院水生生物研究所 螺旋藻γ-亚麻酸的新用途
AU2020260090C9 (en) * 2019-04-15 2023-08-31 Metagenics LLC Novel hemp and PEA formulation and its use
JP2023542340A (ja) * 2020-09-21 2023-10-06 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 代謝物の免疫学的作用
IT202100024464A1 (it) * 2021-09-23 2023-03-23 Epitech Group S P A N-palmitoil-etanolamide e acido docosaesaenoico per l’uso nel trattamento del disturbo dello spettro autistico e di altre sindromi depressive
CN114209683A (zh) * 2021-12-22 2022-03-22 中南大学湘雅三医院 壬二酸在制备治疗炎症性肠病药物中的应用
KR20240164914A (ko) * 2022-03-14 2024-11-21 페라 다이아그노스틱스 앤드 바이올로지컬스 코프. 지방산 조성물

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US5643899A (en) 1992-06-19 1997-07-01 Cellegy Pharmaceuticals, Inc. Lipids for epidermal moisturization and repair of barrier function
JP2007262068A (ja) 2006-03-28 2007-10-11 Epitech Group Srl 免疫系の一般的反応により引き起こされる病態の治療のための医薬組成物
WO2008075978A2 (en) 2006-12-20 2008-06-26 Seperex Nutritionals Limited An extract
DE202008007621U1 (de) 2008-06-04 2008-11-06 Zimmer, Bruno Kosmetisches und Nahrungsmittel aus unterschiedlichen Fettsäuren
JP2011513230A (ja) 2008-02-22 2011-04-28 ライジェル ファーマシューティカルズ， インコーポレイテッド アテローム性動脈硬化症の治療のための２，４−ピリミジンジアミンの使用
WO2013007700A1 (en) 2011-07-11 2013-01-17 Nusca Giovanni Pharmaceutical composition comprising oleic acid, palmitic acid, linoleic acid and linolenic acid
JP2013523891A (ja) 2010-04-13 2013-06-17 ライジェル ファーマシューティカルズ， インコーポレイテッド ２，４−ピリミジンジアミン化合物およびそのプロドラッグならびにそれらの使用
WO2013171316A1 (en) 2012-05-18 2013-11-21 Sanofi Pyridine derivatives and their use in the treatment of conditions associated with pathological thrombus formation

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US5643899A (en) 1992-06-19 1997-07-01 Cellegy Pharmaceuticals, Inc. Lipids for epidermal moisturization and repair of barrier function
JP2007262068A (ja) 2006-03-28 2007-10-11 Epitech Group Srl 免疫系の一般的反応により引き起こされる病態の治療のための医薬組成物
WO2008075978A2 (en) 2006-12-20 2008-06-26 Seperex Nutritionals Limited An extract
JP2011513230A (ja) 2008-02-22 2011-04-28 ライジェル ファーマシューティカルズ， インコーポレイテッド アテローム性動脈硬化症の治療のための２，４−ピリミジンジアミンの使用
DE202008007621U1 (de) 2008-06-04 2008-11-06 Zimmer, Bruno Kosmetisches und Nahrungsmittel aus unterschiedlichen Fettsäuren
JP2013523891A (ja) 2010-04-13 2013-06-17 ライジェル ファーマシューティカルズ， インコーポレイテッド ２，４−ピリミジンジアミン化合物およびそのプロドラッグならびにそれらの使用
WO2013007700A1 (en) 2011-07-11 2013-01-17 Nusca Giovanni Pharmaceutical composition comprising oleic acid, palmitic acid, linoleic acid and linolenic acid
WO2013171316A1 (en) 2012-05-18 2013-11-21 Sanofi Pyridine derivatives and their use in the treatment of conditions associated with pathological thrombus formation
JP2015521183A (ja) 2012-05-18 2015-07-27 サノフイ ピリジン誘導体および病理学的血栓形成に関連する状態の治療へのその使用

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Ｊ．Ｌｉｐｉｄ Ｎｕｔｒ．，２００８年，１７（１），ｐ．３３－４０

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WO2016020828A1 (en) 2016-02-11
JP2023041806A (ja) 2023-03-24
IL250271B (en) 2022-10-01
JP2017523230A (ja) 2017-08-17
CN106714792A (zh) 2017-05-24
US10149827B2 (en) 2018-12-11
ES2976095T3 (es) 2024-07-23
JP7335475B2 (ja) 2023-08-30
EP3177281A1 (en) 2017-06-14
EP3177281B1 (en) 2023-12-06
TW201609084A (zh) 2016-03-16
TWI727926B (zh) 2021-05-21
MA40417A (fr) 2017-06-14
US20170224645A1 (en) 2017-08-10
CO2017001088A2 (es) 2017-04-28
CA2957700C (en) 2022-12-13
FI3177281T3 (fi) 2024-03-13
IL250271A0 (en) 2017-03-30
US9962355B2 (en) 2018-05-08
DK3177281T3 (da) 2024-03-11
US20180243254A1 (en) 2018-08-30
JP2021004260A (ja) 2021-01-14
CA2957700A1 (en) 2016-02-11
BR112017002474A2 (pt) 2017-12-05
IL250271B2 (en) 2023-02-01

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