CN106714792A - 用于治疗炎症性和过敏性病理学的脂肪酸和十六酰胺乙醇的混合物 - Google Patents

用于治疗炎症性和过敏性病理学的脂肪酸和十六酰胺乙醇的混合物 Download PDF

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Publication number
CN106714792A
CN106714792A CN201580042308.5A CN201580042308A CN106714792A CN 106714792 A CN106714792 A CN 106714792A CN 201580042308 A CN201580042308 A CN 201580042308A CN 106714792 A CN106714792 A CN 106714792A
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mixture
acid
weight
present
inflammatory
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Chinese (zh)
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R·米利亚乔
A·萨尔代意
C·米利亚乔
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201580042308.5A 2014-08-08 2015-08-03 用于治疗炎症性和过敏性病理学的脂肪酸和十六酰胺乙醇的混合物 Pending CN106714792A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2014A001474 2014-08-08
ITMI20141474 2014-08-08
PCT/IB2015/055885 WO2016020828A1 (en) 2014-08-08 2015-08-03 Mixture of fatty acids and palmitoylethanolamide for use in the treatment of inflammatory and allergic pathologies

Publications (1)

Publication Number Publication Date
CN106714792A true CN106714792A (zh) 2017-05-24

Family

ID=51663273

Family Applications (1)

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CN201580042308.5A Pending CN106714792A (zh) 2014-08-08 2015-08-03 用于治疗炎症性和过敏性病理学的脂肪酸和十六酰胺乙醇的混合物

Country Status (13)

Country Link
US (2) US9962355B2 (enExample)
EP (1) EP3177281B1 (enExample)
JP (3) JP7118642B2 (enExample)
CN (1) CN106714792A (enExample)
CA (1) CA2957700C (enExample)
CO (1) CO2017001088A2 (enExample)
DK (1) DK3177281T3 (enExample)
ES (1) ES2976095T3 (enExample)
FI (1) FI3177281T3 (enExample)
IL (1) IL250271B2 (enExample)
MA (1) MA40417A (enExample)
TW (1) TWI727926B (enExample)
WO (1) WO2016020828A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893520A (zh) * 2019-03-21 2019-06-18 中国科学院水生生物研究所 螺旋藻γ-亚麻酸的新用途
CN114209683A (zh) * 2021-12-22 2022-03-22 中南大学湘雅三医院 壬二酸在制备治疗炎症性肠病药物中的应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016334086B2 (en) * 2015-10-07 2022-10-20 Cormedix Inc. Skin-penetrating formulation of taurolidine
AU2020260090C9 (en) * 2019-04-15 2023-08-31 Metagenics LLC Novel hemp and PEA formulation and its use
JP2023542340A (ja) * 2020-09-21 2023-10-06 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 代謝物の免疫学的作用
IT202100024464A1 (it) * 2021-09-23 2023-03-23 Epitech Group S P A N-palmitoil-etanolamide e acido docosaesaenoico per l’uso nel trattamento del disturbo dello spettro autistico e di altre sindromi depressive
KR20240164914A (ko) * 2022-03-14 2024-11-21 페라 다이아그노스틱스 앤드 바이올로지컬스 코프. 지방산 조성물

Citations (4)

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US5679667A (en) * 1992-04-24 1997-10-21 Lifegroup S.P.A. Aminoalcohols-N-Acyl derivatives as therapeutical agents against the neurogenic endoneural edema of the peripheral nerve
US20070270496A1 (en) * 2006-03-28 2007-11-22 Epitech Group S.R.L. Pharmaceutical composition for the treatment of pathologies caused by the general response of the immune system
CN103242262A (zh) * 2013-05-24 2013-08-14 厦门大学 N-脂肪酰基乙醇胺水解酶抑制剂及其合成方法和用途
CN103638003A (zh) * 2006-12-20 2014-03-19 新西兰适华利营养有限公司 富含n-酰基乙醇酰胺化合物的组合物

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IT1252865B (it) * 1991-12-31 1995-06-28 Lifegroup Spa N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni
IT1257697B (it) * 1992-04-24 1996-02-01 Lifegroup Spa N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.
KR0179393B1 (ko) 1992-06-19 1999-03-20 린다 에스. 스티븐슨 표피 보습화 및 장벽 기능 치유용 지질
EP0620000A3 (de) * 1992-12-18 1994-11-02 Rhone-Poulenc Rorer Gmbh Kosmetische und/oder pharmazeutische Verwendung von N-Acylalkanolaminen
US5599548A (en) * 1995-05-08 1997-02-04 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides and retinol or retinyl ester
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US5679667A (en) * 1992-04-24 1997-10-21 Lifegroup S.P.A. Aminoalcohols-N-Acyl derivatives as therapeutical agents against the neurogenic endoneural edema of the peripheral nerve
US20070270496A1 (en) * 2006-03-28 2007-11-22 Epitech Group S.R.L. Pharmaceutical composition for the treatment of pathologies caused by the general response of the immune system
CN103638003A (zh) * 2006-12-20 2014-03-19 新西兰适华利营养有限公司 富含n-酰基乙醇酰胺化合物的组合物
CN103242262A (zh) * 2013-05-24 2013-08-14 厦门大学 N-脂肪酰基乙醇胺水解酶抑制剂及其合成方法和用途

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姚婷: "浙江省不同季节贻贝脂肪和脂肪酸成分抗炎生物活性研究", 《浙江工商大学硕士学位论文》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893520A (zh) * 2019-03-21 2019-06-18 中国科学院水生生物研究所 螺旋藻γ-亚麻酸的新用途
CN114209683A (zh) * 2021-12-22 2022-03-22 中南大学湘雅三医院 壬二酸在制备治疗炎症性肠病药物中的应用

Also Published As

Publication number Publication date
WO2016020828A1 (en) 2016-02-11
JP2023041806A (ja) 2023-03-24
IL250271B (en) 2022-10-01
JP2017523230A (ja) 2017-08-17
US10149827B2 (en) 2018-12-11
ES2976095T3 (es) 2024-07-23
JP7335475B2 (ja) 2023-08-30
EP3177281A1 (en) 2017-06-14
EP3177281B1 (en) 2023-12-06
TW201609084A (zh) 2016-03-16
TWI727926B (zh) 2021-05-21
MA40417A (fr) 2017-06-14
US20170224645A1 (en) 2017-08-10
CO2017001088A2 (es) 2017-04-28
CA2957700C (en) 2022-12-13
FI3177281T3 (fi) 2024-03-13
IL250271A0 (en) 2017-03-30
US9962355B2 (en) 2018-05-08
DK3177281T3 (da) 2024-03-11
US20180243254A1 (en) 2018-08-30
JP2021004260A (ja) 2021-01-14
CA2957700A1 (en) 2016-02-11
BR112017002474A2 (pt) 2017-12-05
IL250271B2 (en) 2023-02-01
JP7118642B2 (ja) 2022-08-16

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