ES2976095T3 - Mezcla de ácidos grasos y palmitoiletanolamida para su uso en el tratamiento de patologías inflamatorias y alérgicas - Google Patents

Mezcla de ácidos grasos y palmitoiletanolamida para su uso en el tratamiento de patologías inflamatorias y alérgicas Download PDF

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Publication number
ES2976095T3
ES2976095T3 ES15754028T ES15754028T ES2976095T3 ES 2976095 T3 ES2976095 T3 ES 2976095T3 ES 15754028 T ES15754028 T ES 15754028T ES 15754028 T ES15754028 T ES 15754028T ES 2976095 T3 ES2976095 T3 ES 2976095T3
Authority
ES
Spain
Prior art keywords
mixture
acid
present
weight
palmitoylethanolamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15754028T
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English (en)
Spanish (es)
Inventor
Raffaele Migliaccio
Antonella Sardei
Carmela Migliaccio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ali Res Srl
Original Assignee
Ali Res Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ali Res Srl filed Critical Ali Res Srl
Application granted granted Critical
Publication of ES2976095T3 publication Critical patent/ES2976095T3/es
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES15754028T 2014-08-08 2015-08-03 Mezcla de ácidos grasos y palmitoiletanolamida para su uso en el tratamiento de patologías inflamatorias y alérgicas Active ES2976095T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI20141474 2014-08-08
PCT/IB2015/055885 WO2016020828A1 (en) 2014-08-08 2015-08-03 Mixture of fatty acids and palmitoylethanolamide for use in the treatment of inflammatory and allergic pathologies

Publications (1)

Publication Number Publication Date
ES2976095T3 true ES2976095T3 (es) 2024-07-23

Family

ID=51663273

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15754028T Active ES2976095T3 (es) 2014-08-08 2015-08-03 Mezcla de ácidos grasos y palmitoiletanolamida para su uso en el tratamiento de patologías inflamatorias y alérgicas

Country Status (13)

Country Link
US (2) US9962355B2 (enExample)
EP (1) EP3177281B1 (enExample)
JP (3) JP7118642B2 (enExample)
CN (1) CN106714792A (enExample)
CA (1) CA2957700C (enExample)
CO (1) CO2017001088A2 (enExample)
DK (1) DK3177281T3 (enExample)
ES (1) ES2976095T3 (enExample)
FI (1) FI3177281T3 (enExample)
IL (1) IL250271B2 (enExample)
MA (1) MA40417A (enExample)
TW (1) TWI727926B (enExample)
WO (1) WO2016020828A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3377067A4 (en) * 2015-10-07 2019-07-31 Cormedix Inc. SKIN-PENETRATING FORMULATION OF TAUROLIDINE
CN109893520A (zh) * 2019-03-21 2019-06-18 中国科学院水生生物研究所 螺旋藻γ-亚麻酸的新用途
WO2020214569A1 (en) * 2019-04-15 2020-10-22 Metagenics, Inc. Novel hemp and pea formulation and its use
EP4213821A2 (en) * 2020-09-21 2023-07-26 The Regents of the University of California Immunological effects of metabolites
CA3212050A1 (en) * 2021-03-18 2022-09-22 Weizhen Wang Methods and compositions for treating eye diseases
IT202100014006A1 (it) * 2021-05-28 2022-11-28 Epitech Group S P A Composizione di aciletanolamidi da acidi grassi di olio di oliva
IT202100024464A1 (it) * 2021-09-23 2023-03-23 Epitech Group S P A N-palmitoil-etanolamide e acido docosaesaenoico per l’uso nel trattamento del disturbo dello spettro autistico e di altre sindromi depressive
CN114209683A (zh) * 2021-12-22 2022-03-22 中南大学湘雅三医院 壬二酸在制备治疗炎症性肠病药物中的应用
BR112023010845A2 (pt) * 2022-03-14 2023-10-24 Fera Diagnostics And Biologicals Corp Composições de ácido graxo e métodos

Family Cites Families (22)

* Cited by examiner, † Cited by third party
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IT1252865B (it) * 1991-12-31 1995-06-28 Lifegroup Spa N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni
IT1257697B (it) * 1992-04-24 1996-02-01 Lifegroup Spa N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.
US5679667A (en) 1992-04-24 1997-10-21 Lifegroup S.P.A. Aminoalcohols-N-Acyl derivatives as therapeutical agents against the neurogenic endoneural edema of the peripheral nerve
EP0644764B1 (en) * 1992-06-19 2000-05-17 The Regents of the University of California Lipids for epidermal moisturization and repair of barrier function
EP0620000A3 (de) * 1992-12-18 1994-11-02 Rhone-Poulenc Rorer Gmbh Kosmetische und/oder pharmazeutische Verwendung von N-Acylalkanolaminen
US5599548A (en) * 1995-05-08 1997-02-04 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides and retinol or retinyl ester
US5716627A (en) * 1996-04-25 1998-02-10 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester
JP2000159668A (ja) * 1998-11-26 2000-06-13 Nof Corp サイトカイン抑制剤
JP2000191525A (ja) * 1998-12-25 2000-07-11 Nof Corp 皮膚外用剤組成物
GB9923738D0 (en) 1999-10-07 1999-12-08 Nestle Sa Nutritional composition
US20020143059A1 (en) 2000-12-28 2002-10-03 Sreekumar Pillai Skin care product containing retinoids, retinoid booster and phytoestrogens in a dual compartment package
DE10217131A1 (de) 2001-07-31 2003-02-13 Kuhs Kosmetik Gmbh & Co Kg Topisch applizierbare Zusammensetzung sowie Werkstoffgemisch
DE602006013787D1 (de) 2006-03-28 2010-06-02 Epitech Group Srl Eine Pharmazeutische Zusammensetzung zur Behandlung von Pathologien, die durch die allgemeine Immunantwort verursacht werden
NZ552238A (en) * 2006-12-20 2009-07-31 Seperex Nutritionals Ltd An extract
RU2490015C2 (ru) * 2008-02-22 2013-08-20 Райджел Фармасьютикалз, Инк. Применение 2,4-пиримидиндиаминов для лечения атеросклероза
DE202008007621U1 (de) * 2008-06-04 2008-11-06 Zimmer, Bruno Kosmetisches und Nahrungsmittel aus unterschiedlichen Fettsäuren
SG183565A1 (en) * 2010-03-02 2012-09-27 Imagenetix Inc Compositions comprising myristic acid and uses thereof
JP6067550B2 (ja) * 2010-04-13 2017-01-25 ライジェル ファーマシューティカルズ, インコーポレイテッド 2,4−ピリミジンジアミン化合物およびそのプロドラッグならびにそれらの使用
ITMI20111284A1 (it) * 2011-07-11 2013-01-12 Giovanni Nusca Composizione farmaceutica.
JP2015521183A (ja) 2012-05-18 2015-07-27 サノフイ ピリジン誘導体および病理学的血栓形成に関連する状態の治療へのその使用
ITMI20130354A1 (it) * 2013-03-08 2014-09-09 Again Life Italia Srl Miscela di acidi grassi (f.a.g. fatty acids group) per uso nel trattamento di patologie infiammatorie.
CN103242262A (zh) * 2013-05-24 2013-08-14 厦门大学 N-脂肪酰基乙醇胺水解酶抑制剂及其合成方法和用途

Also Published As

Publication number Publication date
US20180243254A1 (en) 2018-08-30
EP3177281B1 (en) 2023-12-06
IL250271B (en) 2022-10-01
DK3177281T3 (da) 2024-03-11
JP2023041806A (ja) 2023-03-24
IL250271A0 (en) 2017-03-30
US20170224645A1 (en) 2017-08-10
CA2957700C (en) 2022-12-13
US10149827B2 (en) 2018-12-11
US9962355B2 (en) 2018-05-08
EP3177281A1 (en) 2017-06-14
CO2017001088A2 (es) 2017-04-28
IL250271B2 (en) 2023-02-01
FI3177281T3 (fi) 2024-03-13
CN106714792A (zh) 2017-05-24
BR112017002474A2 (pt) 2017-12-05
TW201609084A (zh) 2016-03-16
WO2016020828A1 (en) 2016-02-11
JP2017523230A (ja) 2017-08-17
JP7335475B2 (ja) 2023-08-30
TWI727926B (zh) 2021-05-21
MA40417A (fr) 2017-06-14
CA2957700A1 (en) 2016-02-11
JP7118642B2 (ja) 2022-08-16
JP2021004260A (ja) 2021-01-14

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