IT1252865B - N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni - Google Patents

N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni

Info

Publication number
IT1252865B
IT1252865B ITMI913508A ITMI913508A IT1252865B IT 1252865 B IT1252865 B IT 1252865B IT MI913508 A ITMI913508 A IT MI913508A IT MI913508 A ITMI913508 A IT MI913508A IT 1252865 B IT1252865 B IT 1252865B
Authority
IT
Italy
Prior art keywords
aminoalcohols
autocoids
usable
therapy
local
Prior art date
Application number
ITMI913508A
Other languages
English (en)
Inventor
Valle Francesco Della
Silvana Lorenzi
Jacobus C J J Samson
Valle Federica Della
Original Assignee
Lifegroup Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifegroup Spa filed Critical Lifegroup Spa
Priority to ITMI913508A priority Critical patent/IT1252865B/it
Publication of ITMI913508A0 publication Critical patent/ITMI913508A0/it
Priority to EP92121862A priority patent/EP0550006B1/en
Priority to DE69229944T priority patent/DE69229944T2/de
Priority to AT92121862T priority patent/ATE184193T1/de
Priority to JP4361557A priority patent/JPH05345722A/ja
Priority to CA002086442A priority patent/CA2086442A1/en
Publication of ITMI913508A1 publication Critical patent/ITMI913508A1/it
Priority to US08/148,557 priority patent/US5506224A/en
Application granted granted Critical
Publication of IT1252865B publication Critical patent/IT1252865B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Abstract

N-acilderivati di aminoalcooli scelti fra la etanolamina e la dietanolamina atti al trattamento terapeutico delle patologie in cui si ha degranulazione dei mastociti conseguente ad una iperstimolazione neurogena e/o immunogenica.
ITMI913508A 1991-12-31 1991-12-31 N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni IT1252865B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI913508A IT1252865B (it) 1991-12-31 1991-12-31 N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni
EP92121862A EP0550006B1 (en) 1991-12-31 1992-12-23 Use of N-acyl derivatives of aminoalcohols for the manufacture of a medicament for the treatment of pathologies involving mast cells
DE69229944T DE69229944T2 (de) 1991-12-31 1992-12-23 Verwendung von N-Acylaminoalkoholen zur Herstellung eines Arzneimittels zur Behandlung von Mastzellerkrankungen
AT92121862T ATE184193T1 (de) 1991-12-31 1992-12-23 Verwendung von n-acylaminoalkoholen zur herstellung eines arzneimittels zur behandlung von mastzellerkrankungen
JP4361557A JPH05345722A (ja) 1991-12-31 1992-12-28 アミノアルコールのｎ−アシル誘導体を含む薬剤組成物
CA002086442A CA2086442A1 (en) 1991-12-31 1992-12-30 N-acyl derivatives of aminoalcohols active as local autocoidis and useful in the therapy of autoimmune processes
US08/148,557 US5506224A (en) 1991-12-31 1993-11-08 N-acyl derivatives of aminoalcohols active as local autacoids and useful in the therapy of autoimmune processes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI913508A IT1252865B (it) 1991-12-31 1991-12-31 N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni

Publications (3)

Publication Number Publication Date
ITMI913508A0 ITMI913508A0 (it) 1991-12-31
ITMI913508A1 ITMI913508A1 (it) 1993-07-01
IT1252865B true IT1252865B (it) 1995-06-28

Family

ID=11361452

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI913508A IT1252865B (it) 1991-12-31 1991-12-31 N-acilderivati di aminoalcooli attivi come autocoidi locali ed utilizzabili nella terapia dei processi autoimmuni

Country Status (6)

Country Link
EP (1) EP0550006B1 (it)
JP (1) JPH05345722A (it)
AT (1) ATE184193T1 (it)
CA (1) CA2086442A1 (it)
DE (1) DE69229944T2 (it)
IT (1) IT1252865B (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0620000A3 (de) * 1992-12-18 1994-11-02 Rhone-Poulenc Rorer Gmbh Kosmetische und/oder pharmazeutische Verwendung von N-Acylalkanolaminen
IT1271266B (it) * 1994-12-14 1997-05-27 Valle Francesco Della Impiego terapeutico di ammidi di acidi mono e bicarbossilici con amminoalcoli,selettivamente attive sul recettore periferico dei cannabinoidi
US5614198A (en) * 1995-07-25 1997-03-25 The Trustees Of The University Of Pennsylvania Bowman-Birk Inhibitor compositions for treatment of inflammatory disease
ATE279185T1 (de) * 1995-12-28 2004-10-15 Mitsubishi Pharma Corp 2-amino-2-(2-(4-octylphenyl)ethyl)propan-1,3-di l enthaltendes arzneimittel zur topischen anwendung zur behandlung von erkrankungen die durch eine störung des immunsystems hervorgerufen werden
JPH09278653A (ja) * 1996-04-05 1997-10-28 Santen Pharmaceut Co Ltd 網膜疾患治療剤
AU728488B2 (en) * 1997-04-02 2001-01-11 Sankyo Company Limited Dithiolan derivatives, their preparation and their therapeutic effect
JP2000169371A (ja) * 1998-10-02 2000-06-20 Sankyo Co Ltd ジチオラン誘導体を含有する医薬
JP2000169443A (ja) * 1998-10-02 2000-06-20 Sankyo Co Ltd ジチオ―ル誘導体
WO2001004083A1 (en) 1999-07-07 2001-01-18 Innovet Italia S.R.L. Covalent derivatives of alkanolamides of monocarboxylic and dicarboxylic acids functionally active on the cb2 cannabinoid receptor
DK1207870T3 (da) * 1999-08-06 2005-08-01 Innovet Italia Srl Farmaceutiske præparater, der indeholder N-palmitoylethanolamid og anvendelse deraf
GB0104268D0 (en) 2001-02-21 2001-04-11 Unilever Plc Antiperspirant or deodorant compositions
JP2007191495A (ja) * 2001-10-22 2007-08-02 Santen Pharmaceut Co Ltd 掻痒治療剤
TWI250023B (en) * 2001-10-22 2006-03-01 Santen Pharmaceutical Co Ltd Pharmaceutical composition for itch treating agent
DE60329981D1 (de) 2002-02-19 2009-12-24 Shionogi & Co Antipruriginosa
EP1714644B1 (en) * 2005-04-19 2012-08-08 Innovet Italia S.r.l. Pharmaceutical compositions for the treatment of chronic ulcerations
ES2344920T3 (es) * 2006-03-28 2010-09-09 Epitech Group S.R.L. Composicion farmaceutica para el tratamiento de patologias provocadas por la respuesta general del sistema inmutario.
JPWO2008111296A1 (ja) 2007-03-09 2010-06-24 国立大学法人京都大学 角化の亢進に起因する皮膚疾患の予防及び治療のための医薬
US9623000B2 (en) 2008-07-31 2017-04-18 Dekel Pharmaceuticals Ltd Compositions and methods for treating inflammatory disorders
ES2548190T3 (es) 2009-09-07 2015-10-14 Epitech Group S.P.A. Composición que contiene palmitoiletanolamida ultramicronizada
JP5783839B2 (ja) * 2011-08-02 2015-09-24 クラリアント・インターナシヨナル・リミテツド 脂肪酸モノアルカノールアミドの製造方法
EP3177281B1 (en) * 2014-08-08 2023-12-06 Ali Research S.R.L. Mixture of fatty acids and palmitoylethanolamide for use in the treatment of inflammatory and allergic pathologies
NL2014464B1 (en) 2015-03-16 2017-01-13 Vanderbilt Science Holding Ltd Composition for use in the treatment of neuropathic pain.
CN112225669A (zh) * 2020-10-22 2021-01-15 广东椰氏实业股份有限公司 一种脂肪酸酰胺mipa及其制备方法和应用
CN113372245B (zh) * 2021-06-17 2023-01-13 仪征市海帆化工有限公司 一种n-苯甲酰基-o,o-对甲苯磺酰基-二乙醇胺的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2140369A1 (en) * 1971-06-11 1973-01-19 Ceskoslovenska Akademie Ved Ethanol palmitamide - for treatment of upper respiratory infections and for detoxication

Also Published As

Publication number Publication date
DE69229944T2 (de) 2000-01-13
ITMI913508A1 (it) 1993-07-01
EP0550006B1 (en) 1999-09-08
JPH05345722A (ja) 1993-12-27
DE69229944D1 (de) 1999-10-14
ITMI913508A0 (it) 1991-12-31
EP0550006A3 (en) 1994-11-23
CA2086442A1 (en) 1993-07-01
EP0550006A2 (en) 1993-07-07
ATE184193T1 (de) 1999-09-15

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