JP6993228B2 - 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 - Google Patents
抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 Download PDFInfo
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- JP6993228B2 JP6993228B2 JP2017526560A JP2017526560A JP6993228B2 JP 6993228 B2 JP6993228 B2 JP 6993228B2 JP 2017526560 A JP2017526560 A JP 2017526560A JP 2017526560 A JP2017526560 A JP 2017526560A JP 6993228 B2 JP6993228 B2 JP 6993228B2
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2881—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- C12Y304/23—Aspartic endopeptidases (3.4.23)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462081965P | 2014-11-19 | 2014-11-19 | |
| US62/081,965 | 2014-11-19 | ||
| PCT/US2015/061402 WO2016081640A1 (en) | 2014-11-19 | 2015-11-18 | Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505652A JP2018505652A (ja) | 2018-03-01 |
| JP2018505652A5 JP2018505652A5 (enExample) | 2018-12-27 |
| JP6993228B2 true JP6993228B2 (ja) | 2022-03-03 |
Family
ID=54780464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017526560A Active JP6993228B2 (ja) | 2014-11-19 | 2015-11-18 | 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11008403B2 (enExample) |
| EP (1) | EP3221361B1 (enExample) |
| JP (1) | JP6993228B2 (enExample) |
| CN (1) | CN107250158B (enExample) |
| WO (1) | WO2016081640A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3221364B1 (en) | 2014-11-19 | 2020-12-16 | Genentech, Inc. | Antibodies against bace1 and use thereof for neural disease immunotherapy |
| MX2018010485A (es) | 2016-03-04 | 2019-01-10 | Jn Biosciences Llc | Anticuerpos para inmunoreceptor de celulas t con dominios de ig e itim (tigit). |
| EP3560955A4 (en) | 2016-12-26 | 2020-12-23 | Kyowa Kirin Co., Ltd. | ANTIBODIES CAPABLE OF BINDING TO MYELIN OLIGODENDROCYTE GLYCOPROTEIN |
| JP7617603B2 (ja) | 2017-01-11 | 2025-01-20 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | R-スポンジン(rspo)サロゲート分子 |
| AU2018211985B2 (en) | 2017-01-26 | 2025-02-13 | Surrozen Operating, Inc. | Tissue-specific Wnt signal enhancing molecules and uses thereof |
| EP4628586A3 (en) | 2017-02-17 | 2026-01-14 | Denali Therapeutics Inc. | Transferrin receptor transgenic models |
| RS63818B1 (sr) | 2017-02-17 | 2023-01-31 | Denali Therapeutics Inc | Konstruisani polipeptidi za vezivanje za receptor transferina |
| CA3053381A1 (en) | 2017-02-17 | 2018-08-23 | Denali Therapeutics Inc. | Engineered polypeptides |
| WO2019032955A1 (en) * | 2017-08-10 | 2019-02-14 | Denali Therapeutics Inc. | MODIFIED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES |
| BR112020005271A2 (pt) | 2017-10-02 | 2020-09-15 | Denali Therapeutics Inc. | proteína, polipeptídeo, polinucleotídeo, vetor, célula hospedeira, método para produção de um polipeptídeo, métodos de tratamento de um distúrbio, de diminuição do acúmulo, de monitoramento, de transporte de um agente e de tratamento de um lsd e composição farmacêutica |
| WO2019094576A1 (en) * | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Bace-tau bispecific antibodies |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
| CN112040985A (zh) | 2018-02-07 | 2020-12-04 | 瑞泽恩制药公司 | 用于递送治疗性蛋白质的方法和组合物 |
| CN112424358B (zh) | 2018-06-26 | 2025-07-01 | 协和麒麟株式会社 | 与细胞粘附分子3结合的抗体 |
| CA3104997A1 (en) | 2018-06-26 | 2020-01-02 | Kyowa Kirin Co., Ltd. | Antibody binding to chondroitin sulfate proteoglycan 5 |
| JP2021530223A (ja) | 2018-07-09 | 2021-11-11 | スロゼン, インコーポレイテッド | 組織特異性Wntシグナル増強分子及びその使用 |
| CN113164594A (zh) * | 2018-11-20 | 2021-07-23 | 株式会社英仙蛋白质科学 | 向细胞内摄入铁的抑制剂 |
| KR102991359B1 (ko) * | 2018-12-28 | 2026-07-16 | 쿄와 기린 가부시키가이샤 | TfR에 결합하는 이중 특이적 항체 |
| US20230220098A1 (en) * | 2019-09-04 | 2023-07-13 | Perseus Proteomics Inc. | Therapeutic drug for polycythemia |
| WO2021076931A1 (en) * | 2019-10-18 | 2021-04-22 | Centivax, Inc. | Antibodies and uses thereof |
| BR112022012230A2 (pt) | 2019-12-23 | 2022-08-30 | Denali Therapeutics Inc | Variantes de progranulina |
| EP4085251B1 (en) * | 2020-01-02 | 2024-07-31 | F. Hoffmann-La Roche AG | Method for determining the amount of a therapeutic antibody in the brain |
| KR20220164773A (ko) * | 2020-04-08 | 2022-12-13 | 앨리어다 테라퓨틱스, 인코포레이티드 | 혈액-뇌 장벽 전달용 조성물 및 방법 |
| TW202210514A (zh) | 2020-06-02 | 2022-03-16 | 美商阿克思生物科學有限公司 | 針對tigit的抗體 |
| CR20230178A (es) | 2020-10-14 | 2023-07-26 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas sulfoglucosamina sulfohidrolasa y métodos de estas |
| WO2022104280A1 (en) | 2020-11-16 | 2022-05-19 | Surrozen Operating, Inc. | Liver-specific wnt signal enhancing molecules and uses thereof |
| CN112409487B (zh) * | 2020-11-27 | 2022-04-29 | 宁波赛珀生物技术有限公司 | 抗可溶性转铁蛋白受体抗体及其应用 |
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| CN107250158A (zh) | 2017-10-13 |
| WO2016081640A1 (en) | 2016-05-26 |
| EP3221361B1 (en) | 2021-04-21 |
| HK1245289A1 (zh) | 2018-08-24 |
| CN107250158B (zh) | 2022-03-25 |
| EP3221361A1 (en) | 2017-09-27 |
| US11008403B2 (en) | 2021-05-18 |
| JP2018505652A (ja) | 2018-03-01 |
| US20180057604A1 (en) | 2018-03-01 |
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