JP6993228B2 - 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 - Google Patents
抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 Download PDFInfo
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- JP6993228B2 JP6993228B2 JP2017526560A JP2017526560A JP6993228B2 JP 6993228 B2 JP6993228 B2 JP 6993228B2 JP 2017526560 A JP2017526560 A JP 2017526560A JP 2017526560 A JP2017526560 A JP 2017526560A JP 6993228 B2 JP6993228 B2 JP 6993228B2
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2881—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462081965P | 2014-11-19 | 2014-11-19 | |
| US62/081,965 | 2014-11-19 | ||
| PCT/US2015/061402 WO2016081640A1 (en) | 2014-11-19 | 2015-11-18 | Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505652A JP2018505652A (ja) | 2018-03-01 |
| JP2018505652A5 JP2018505652A5 (enExample) | 2018-12-27 |
| JP6993228B2 true JP6993228B2 (ja) | 2022-03-03 |
Family
ID=54780464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017526560A Active JP6993228B2 (ja) | 2014-11-19 | 2015-11-18 | 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11008403B2 (enExample) |
| EP (1) | EP3221361B1 (enExample) |
| JP (1) | JP6993228B2 (enExample) |
| CN (1) | CN107250158B (enExample) |
| WO (1) | WO2016081640A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6859259B2 (ja) | 2014-11-19 | 2021-04-14 | ジェネンテック, インコーポレイテッド | BACElに対する抗体及び神経疾患免疫療法のためのその使用 |
| US10537633B2 (en) | 2016-03-04 | 2020-01-21 | Jn Biosciences Llc | Antibodies to TIGIT |
| CA3297793A1 (en) | 2016-12-26 | 2026-03-02 | Kagoshima University | Antibody which binds to myelin oligodendrocyte glycoprotein |
| US11993645B2 (en) | 2017-01-11 | 2024-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions comprising R-Spondin (RSPO) surrogate molecules |
| WO2018140821A1 (en) | 2017-01-26 | 2018-08-02 | Surrozen, Inc. | Tissue-specific wnt signal enhancing molecules and uses thereof |
| US10143187B2 (en) | 2017-02-17 | 2018-12-04 | Denali Therapeutics Inc. | Transferrin receptor transgenic models |
| CN110506055A (zh) | 2017-02-17 | 2019-11-26 | 戴纳立制药公司 | 工程改造的转铁蛋白受体结合多肽 |
| US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
| CA3053381A1 (en) * | 2017-02-17 | 2018-08-23 | Denali Therapeutics Inc. | Engineered polypeptides |
| EP3665194A4 (en) * | 2017-08-10 | 2021-07-07 | Denali Therapeutics Inc. | AFFINITY BASED METHODS OF USING TRANSFERRIN RECEPTOR BINDING PROTEINS |
| CR20200129A (es) | 2017-10-02 | 2020-08-22 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas de terapia de reemplazo de enzimas |
| WO2019094576A1 (en) * | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Bace-tau bispecific antibodies |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
| US12258597B2 (en) | 2018-02-07 | 2025-03-25 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for therapeutic protein delivery |
| TWI857959B (zh) | 2018-06-26 | 2024-10-11 | 日商協和麒麟股份有限公司 | 與細胞黏著分子3 結合之抗體 |
| JP7397444B2 (ja) | 2018-06-26 | 2023-12-13 | 協和キリン株式会社 | コンドロイチン硫酸プロテオグリカン-5に結合する抗体 |
| CA3104868A1 (en) | 2018-07-09 | 2020-01-16 | Surrozen, Inc. | Tissue-specific wnt signal enhancing molecules and uses thereof |
| WO2020105621A1 (ja) * | 2018-11-20 | 2020-05-28 | 株式会社ペルセウスプロテオミクス | 細胞内への鉄の取り込み阻害剤 |
| WO2020138487A1 (ja) * | 2018-12-28 | 2020-07-02 | 協和キリン株式会社 | TfRに結合するバイスペシフィック抗体 |
| EP4026560A4 (en) * | 2019-09-04 | 2023-10-25 | Perseus Proteomics Inc. | THERAPEUTIC AGENT AGAINST POLYCYTHEMIA |
| WO2021076931A1 (en) * | 2019-10-18 | 2021-04-22 | Centivax, Inc. | Antibodies and uses thereof |
| PH12022551598A1 (en) | 2019-12-23 | 2023-11-20 | Denali Therapeutics Inc | Progranulin variants |
| EP4085251B1 (en) * | 2020-01-02 | 2024-07-31 | F. Hoffmann-La Roche AG | Method for determining the amount of a therapeutic antibody in the brain |
| CN121754667A (zh) * | 2020-04-08 | 2026-03-31 | 阿里亚达治疗公司 | 用于血脑屏障递送的组合物和方法 |
| MX2022015157A (es) | 2020-06-02 | 2023-01-16 | Arcus Biosciences Inc | Anticuerpos para tigit. |
| EP4229192A1 (en) | 2020-10-14 | 2023-08-23 | Denali Therapeutics Inc. | Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof |
| JP2023549854A (ja) | 2020-11-16 | 2023-11-29 | スロゼン オペレーティング, インコーポレイテッド | 肝臓特異的Wntシグナル増強分子およびその使用 |
| CN112409487B (zh) * | 2020-11-27 | 2022-04-29 | 宁波赛珀生物技术有限公司 | 抗可溶性转铁蛋白受体抗体及其应用 |
| WO2023122647A2 (en) * | 2021-12-22 | 2023-06-29 | The University Of Chicago | Methods for detecting or treating influenza infections |
| CN114437207B (zh) * | 2022-01-10 | 2023-07-21 | 中国人民解放军空军军医大学 | 具有中和活性的人源性抗汉滩病毒(HTNV)Fab抗体及应用 |
| WO2023196954A2 (en) * | 2022-04-08 | 2023-10-12 | The Wistar Institute Of Anatomy And Biology | Bispecific binding molecules that target fshr and cd3 |
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| JP2018505652A (ja) | 2018-03-01 |
| US20180057604A1 (en) | 2018-03-01 |
| HK1245289A1 (zh) | 2018-08-24 |
| US11008403B2 (en) | 2021-05-18 |
| CN107250158A (zh) | 2017-10-13 |
| EP3221361A1 (en) | 2017-09-27 |
| CN107250158B (zh) | 2022-03-25 |
| EP3221361B1 (en) | 2021-04-21 |
| WO2016081640A1 (en) | 2016-05-26 |
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