JP6993228B2 - 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 - Google Patents
抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 Download PDFInfo
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- JP6993228B2 JP6993228B2 JP2017526560A JP2017526560A JP6993228B2 JP 6993228 B2 JP6993228 B2 JP 6993228B2 JP 2017526560 A JP2017526560 A JP 2017526560A JP 2017526560 A JP2017526560 A JP 2017526560A JP 6993228 B2 JP6993228 B2 JP 6993228B2
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2881—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462081965P | 2014-11-19 | 2014-11-19 | |
| US62/081,965 | 2014-11-19 | ||
| PCT/US2015/061402 WO2016081640A1 (en) | 2014-11-19 | 2015-11-18 | Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505652A JP2018505652A (ja) | 2018-03-01 |
| JP2018505652A5 JP2018505652A5 (enExample) | 2018-12-27 |
| JP6993228B2 true JP6993228B2 (ja) | 2022-03-03 |
Family
ID=54780464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017526560A Active JP6993228B2 (ja) | 2014-11-19 | 2015-11-18 | 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11008403B2 (enExample) |
| EP (1) | EP3221361B1 (enExample) |
| JP (1) | JP6993228B2 (enExample) |
| CN (1) | CN107250158B (enExample) |
| WO (1) | WO2016081640A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6859259B2 (ja) | 2014-11-19 | 2021-04-14 | ジェネンテック, インコーポレイテッド | BACElに対する抗体及び神経疾患免疫療法のためのその使用 |
| SG11201806992VA (en) | 2016-03-04 | 2018-09-27 | Jn Biosciences Llc | Antibodies to tigit |
| CN110536901B (zh) | 2016-12-26 | 2024-06-18 | 协和麒麟株式会社 | 与髓鞘少突胶质细胞糖蛋白结合的抗体 |
| AU2018207440B2 (en) | 2017-01-11 | 2022-06-02 | The Board Of Trustees Of The Leland Stanford Junior University | R-spondin (RSPO) surrogate molecules |
| CN110234662A (zh) | 2017-01-26 | 2019-09-13 | 瑟罗泽恩公司 | 组织特异性wnt信号增强分子和其用途 |
| SG11201907427YA (en) | 2017-02-17 | 2019-09-27 | Denali Therapeutics Inc | Engineered transferrin receptor binding polypeptides |
| US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
| EP3583119A2 (en) * | 2017-02-17 | 2019-12-25 | Denali Therapeutics Inc. | Engineered polypeptides |
| US10143187B2 (en) | 2017-02-17 | 2018-12-04 | Denali Therapeutics Inc. | Transferrin receptor transgenic models |
| CN111148757B (zh) * | 2017-08-10 | 2024-06-21 | 戴纳立制药公司 | 工程改造的转铁蛋白受体结合多肽 |
| JP2021500857A (ja) | 2017-10-02 | 2021-01-14 | デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. | 酵素補充療法用酵素を含む融合タンパク質 |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
| WO2019094576A1 (en) * | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Bace-tau bispecific antibodies |
| WO2019157224A1 (en) | 2018-02-07 | 2019-08-15 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for therapeutic protein delivery |
| WO2020004492A1 (ja) | 2018-06-26 | 2020-01-02 | 協和キリン株式会社 | Cell Adhesion Molecule3に結合する抗体 |
| WO2020004490A1 (ja) | 2018-06-26 | 2020-01-02 | 協和キリン株式会社 | コンドロイチン硫酸プロテオグリカン-5に結合する抗体 |
| US12466884B2 (en) | 2018-07-09 | 2025-11-11 | Surrozen Operating, Inc. | Tissue-specific WNT signal enhancing molecules and uses |
| JP7410051B2 (ja) * | 2018-11-20 | 2024-01-09 | 株式会社ペルセウスプロテオミクス | 細胞内への鉄の取り込み阻害剤 |
| US12258413B2 (en) * | 2018-12-28 | 2025-03-25 | Kyowa Kirin Co., Ltd. | Bispecific antibody binding to TfR |
| US20230220098A1 (en) * | 2019-09-04 | 2023-07-13 | Perseus Proteomics Inc. | Therapeutic drug for polycythemia |
| WO2021076931A1 (en) * | 2019-10-18 | 2021-04-22 | Centivax, Inc. | Antibodies and uses thereof |
| MX2022007486A (es) | 2019-12-23 | 2022-06-29 | Denali Therapeutics Inc | Variantes de progranulina. |
| TWI766512B (zh) * | 2020-01-02 | 2022-06-01 | 瑞士商赫孚孟拉羅股份公司 | 用於判定腦中的治療性抗體量之方法 |
| IL297148A (en) * | 2020-04-08 | 2022-12-01 | Janssen Biotech Inc | Compositions and methods for blood-brain barrier delivery |
| CN115698068A (zh) | 2020-06-02 | 2023-02-03 | 艾库斯生物科学有限公司 | 抗tigit抗体 |
| IL302029A (en) | 2020-10-14 | 2023-06-01 | Denali Therapeutics Inc | Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof |
| TW202233656A (zh) | 2020-11-16 | 2022-09-01 | 美商蘇羅森營運公司 | 肝特異性wnt訊號增強分子及其用途 |
| CN112409487B (zh) * | 2020-11-27 | 2022-04-29 | 宁波赛珀生物技术有限公司 | 抗可溶性转铁蛋白受体抗体及其应用 |
| WO2023122647A2 (en) * | 2021-12-22 | 2023-06-29 | The University Of Chicago | Methods for detecting or treating influenza infections |
| CN114437207B (zh) * | 2022-01-10 | 2023-07-21 | 中国人民解放军空军军医大学 | 具有中和活性的人源性抗汉滩病毒(HTNV)Fab抗体及应用 |
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| EP3221361B1 (en) | 2021-04-21 |
| JP2018505652A (ja) | 2018-03-01 |
| CN107250158B (zh) | 2022-03-25 |
| WO2016081640A1 (en) | 2016-05-26 |
| HK1245289A1 (zh) | 2018-08-24 |
| US20180057604A1 (en) | 2018-03-01 |
| US11008403B2 (en) | 2021-05-18 |
| CN107250158A (zh) | 2017-10-13 |
| EP3221361A1 (en) | 2017-09-27 |
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