JP6993228B2 - 抗トランスフェリン受容体／抗ｂａｃｅ１多重特異性抗体および使用方法 - Google Patents

抗トランスフェリン受容体／抗ｂａｃｅ１多重特異性抗体および使用方法 Download PDF

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JP6993228B2
JP6993228B2 JP2017526560A JP2017526560A JP6993228B2 JP 6993228 B2 JP6993228 B2 JP 6993228B2 JP 2017526560 A JP2017526560 A JP 2017526560A JP 2017526560 A JP2017526560 A JP 2017526560A JP 6993228 B2 JP6993228 B2 JP 6993228B2
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antibody
seq
hvr
nos
sequence
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JP2018505652A5 (enExample
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イーチン リウ，
ジャスビンダル アトウォル，
セシリア プイ チー チウ，
ライアン ジェー． ワッツ，
イェン ウー，
エリック クラウランド，
マイケル フェルトハウス，
イン チャン，
ジョイ ユイ ズッケロ，
ジェシカ カウチ，
マーク エス． デニス，
ジェームズ エー． アーンスト，
グレゴリー エー． ラザール，
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Genentech Inc
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Genentech Inc
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JP2017526560A 2014-11-19 2015-11-18 抗トランスフェリン受容体／抗ｂａｃｅ１多重特異性抗体および使用方法 Active JP6993228B2 (ja)

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US201462081965P 2014-11-19 2014-11-19
US62/081,965 2014-11-19
PCT/US2015/061402 WO2016081640A1 (en) 2014-11-19 2015-11-18 Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use

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JP2018505652A5 JP2018505652A5 (enExample) 2018-12-27
JP6993228B2 true JP6993228B2 (ja) 2022-03-03

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CN116514976A (zh) 2016-03-04 2023-08-01 Jn生物科学有限责任公司 针对tigit的抗体
US11117963B2 (en) 2016-12-26 2021-09-14 Kyowa Hakko Kirin Co., Ltd. Antibody which binds to myelin oligodendrocyte glycoprotein
EP3568158A4 (en) 2017-01-11 2020-11-18 The Board of Trustees of the Leland Stanford Junior University R-SPONDIN SUBSTITUTION MOLECULES (RSPO)
WO2018140821A1 (en) 2017-01-26 2018-08-02 Surrozen, Inc. Tissue-specific wnt signal enhancing molecules and uses thereof
CN110506054A (zh) * 2017-02-17 2019-11-26 戴纳立制药公司 经工程改造的多肽
US10457717B2 (en) 2017-02-17 2019-10-29 Denali Therapeutics Inc. Engineered polypeptides
NZ756763A (en) 2017-02-17 2023-04-28 Denali Therapeutics Inc Engineered transferrin receptor binding polypeptides
US10143187B2 (en) 2017-02-17 2018-12-04 Denali Therapeutics Inc. Transferrin receptor transgenic models
HUE063021T2 (hu) * 2017-08-10 2023-12-28 Denali Therapeutics Inc Mesterségesen elõállított transzferrin receptor-kötõ polipeptidek
MX2020002918A (es) 2017-10-02 2020-07-22 Denali Therapeutics Inc Proteinas de fusion que comprenden enzimas de terapia de reemplazo de enzimas.
WO2019094576A1 (en) * 2017-11-08 2019-05-16 Denali Therapeutics Inc. Bace-tau bispecific antibodies
WO2019094608A1 (en) 2017-11-08 2019-05-16 Denali Therapeutics Inc. Anti-bace1 antibodies and methods of use thereof
CN112040985A (zh) 2018-02-07 2020-12-04 瑞泽恩制药公司 用于递送治疗性蛋白质的方法和组合物
CN112424358B (zh) 2018-06-26 2025-07-01 协和麒麟株式会社 与细胞粘附分子3结合的抗体
JP7397444B2 (ja) 2018-06-26 2023-12-13 協和キリン株式会社 コンドロイチン硫酸プロテオグリカン－５に結合する抗体
EP3820499A4 (en) 2018-07-09 2022-07-13 Surrozen Operating, Inc. TISSUE SPECIFIC WNT SIGNAL ENHANCEMENT MOLECULES AND USES
JP7410051B2 (ja) * 2018-11-20 2024-01-09 株式会社ペルセウスプロテオミクス 細胞内への鉄の取り込み阻害剤
WO2020138487A1 (ja) * 2018-12-28 2020-07-02 協和キリン株式会社 ＴｆＲに結合するバイスペシフィック抗体
WO2021045184A1 (ja) * 2019-09-04 2021-03-11 株式会社ペルセウスプロテオミクス 多血症治療薬
WO2021076931A1 (en) * 2019-10-18 2021-04-22 Centivax, Inc. Antibodies and uses thereof
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