JP6993228B2 - 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 - Google Patents
抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 Download PDFInfo
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- JP6993228B2 JP6993228B2 JP2017526560A JP2017526560A JP6993228B2 JP 6993228 B2 JP6993228 B2 JP 6993228B2 JP 2017526560 A JP2017526560 A JP 2017526560A JP 2017526560 A JP2017526560 A JP 2017526560A JP 6993228 B2 JP6993228 B2 JP 6993228B2
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2881—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- C12Y304/23—Aspartic endopeptidases (3.4.23)
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- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2319/00—Fusion polypeptide
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462081965P | 2014-11-19 | 2014-11-19 | |
| US62/081,965 | 2014-11-19 | ||
| PCT/US2015/061402 WO2016081640A1 (en) | 2014-11-19 | 2015-11-18 | Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505652A JP2018505652A (ja) | 2018-03-01 |
| JP2018505652A5 JP2018505652A5 (enExample) | 2018-12-27 |
| JP6993228B2 true JP6993228B2 (ja) | 2022-03-03 |
Family
ID=54780464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017526560A Active JP6993228B2 (ja) | 2014-11-19 | 2015-11-18 | 抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11008403B2 (enExample) |
| EP (1) | EP3221361B1 (enExample) |
| JP (1) | JP6993228B2 (enExample) |
| CN (1) | CN107250158B (enExample) |
| WO (1) | WO2016081640A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6859259B2 (ja) | 2014-11-19 | 2021-04-14 | ジェネンテック, インコーポレイテッド | BACElに対する抗体及び神経疾患免疫療法のためのその使用 |
| IL261188B (en) | 2016-03-04 | 2022-08-01 | Jn Biosciences Llc | An anti-tigit antibody that binds to the tigit polypeptide on one or more amino acid residues |
| CN118638228A (zh) | 2016-12-26 | 2024-09-13 | 协和麒麟株式会社 | 与髓鞘少突胶质细胞糖蛋白结合的抗体 |
| US11993645B2 (en) | 2017-01-11 | 2024-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions comprising R-Spondin (RSPO) surrogate molecules |
| WO2018140821A1 (en) | 2017-01-26 | 2018-08-02 | Surrozen, Inc. | Tissue-specific wnt signal enhancing molecules and uses thereof |
| PT3583120T (pt) | 2017-02-17 | 2022-12-15 | Denali Therapeutics Inc | Polipeptídeos de ligação ao recetor de transferrina manipulados |
| US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
| CA3053381A1 (en) * | 2017-02-17 | 2018-08-23 | Denali Therapeutics Inc. | Engineered polypeptides |
| US10143187B2 (en) | 2017-02-17 | 2018-12-04 | Denali Therapeutics Inc. | Transferrin receptor transgenic models |
| JP2020530465A (ja) * | 2017-08-10 | 2020-10-22 | デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. | トランスフェリン受容体結合タンパク質を使用するための、親和性に基づく方法 |
| BR112020005271A2 (pt) | 2017-10-02 | 2020-09-15 | Denali Therapeutics Inc. | proteína, polipeptídeo, polinucleotídeo, vetor, célula hospedeira, método para produção de um polipeptídeo, métodos de tratamento de um distúrbio, de diminuição do acúmulo, de monitoramento, de transporte de um agente e de tratamento de um lsd e composição farmacêutica |
| WO2019094576A1 (en) * | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Bace-tau bispecific antibodies |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
| KR20200118151A (ko) | 2018-02-07 | 2020-10-14 | 리제너론 파마슈티칼스 인코포레이티드 | 치료 단백질 전달을 위한 방법 및 조성물 |
| WO2020004490A1 (ja) | 2018-06-26 | 2020-01-02 | 協和キリン株式会社 | コンドロイチン硫酸プロテオグリカン-5に結合する抗体 |
| EP3816290A4 (en) | 2018-06-26 | 2022-03-30 | Kyowa Kirin Co., Ltd. | Antibody binding to cell adhesion molecule 3 |
| AU2019301633A1 (en) | 2018-07-09 | 2021-01-28 | Surrozen Operating, Inc. | Tissue-specific Wnt signal enhancing molecules and uses |
| KR20210093974A (ko) * | 2018-11-20 | 2021-07-28 | 가부시키가이샤 페르세우스 프로테오믹스 | 세포내 철 흡수 억제제 |
| MX2021007797A (es) * | 2018-12-28 | 2021-10-26 | Kyowa Kirin Co Ltd | Anticuerpo biespecifico que se une al receptor de transferrina (tfr). |
| EP4026560A4 (en) * | 2019-09-04 | 2023-10-25 | Perseus Proteomics Inc. | THERAPEUTIC AGENT AGAINST POLYCYTHEMIA |
| US20210147566A1 (en) * | 2019-10-18 | 2021-05-20 | Distributed Bio, Inc. | Antibodies and uses thereof |
| IL293994A (en) | 2019-12-23 | 2022-08-01 | Denali Therapeutics Inc | Progranulin variants, compositions comprising same and uses thereof |
| US11913945B2 (en) * | 2020-01-02 | 2024-02-27 | Hoffmann-La Roche Inc. | Method for determining the amount of a therapeutic antibody in the brain |
| MX2022012635A (es) * | 2020-04-08 | 2023-01-11 | Aliada Therapeutics Inc | Composiciones y métodos para distribución de barrera hematoencefálica. |
| CR20220611A (es) | 2020-06-02 | 2023-06-07 | Arcus Biosciences Inc | Anticuerpos anti-tigit |
| PE20231931A1 (es) | 2020-10-14 | 2023-12-01 | Denali Therapeutics Inc | Proteinas de fusion que comprenden enzimas sulfoglucosamina sulfohidrolasa y metodos de estas |
| JP2023549854A (ja) | 2020-11-16 | 2023-11-29 | スロゼン オペレーティング, インコーポレイテッド | 肝臓特異的Wntシグナル増強分子およびその使用 |
| CN112409487B (zh) * | 2020-11-27 | 2022-04-29 | 宁波赛珀生物技术有限公司 | 抗可溶性转铁蛋白受体抗体及其应用 |
| WO2023122647A2 (en) * | 2021-12-22 | 2023-06-29 | The University Of Chicago | Methods for detecting or treating influenza infections |
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| CN107250158B (zh) | 2022-03-25 |
| CN107250158A (zh) | 2017-10-13 |
| US20180057604A1 (en) | 2018-03-01 |
| WO2016081640A1 (en) | 2016-05-26 |
| EP3221361B1 (en) | 2021-04-21 |
| HK1245289A1 (zh) | 2018-08-24 |
| EP3221361A1 (en) | 2017-09-27 |
| US11008403B2 (en) | 2021-05-18 |
| JP2018505652A (ja) | 2018-03-01 |
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