JP6762299B2 - 免疫調節剤 - Google Patents

免疫調節剤 Download PDF

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JP6762299B2
JP6762299B2 JP2017524423A JP2017524423A JP6762299B2 JP 6762299 B2 JP6762299 B2 JP 6762299B2 JP 2017524423 A JP2017524423 A JP 2017524423A JP 2017524423 A JP2017524423 A JP 2017524423A JP 6762299 B2 JP6762299 B2 JP 6762299B2
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Japan
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cyclohexyl
fluoroquinoline
ethyl
benzamide
mmol
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JP2017524423A
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Japanese (ja)
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JP2017538677A (ja
JP2017538677A5 (OSRAM
Inventor
ヒラリー・プレイク・ベック
フアン・カルロス・ハエン
マクシム・オシポフ
ジェイ・パトリック・パワーズ
モーリーン・ケイ・ライリー
ハンター・ポール・シュナトナ
ジェイムズ・ロス・ウォーカー
ミハイル・ジビンスキー
ジェイムズ・アーロン・バログ
デイビッド・ケイ・ウィリアムズ
ジェイ・エイ・マークウォルダー
スティーブン・ピー・サイツ
エミリー・シャーロット・チャーニー
リーピン・ジャン
ウェイファン・シャン
グオ・ウェイウェイ
オードリス・ホアン
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Flexus Bioscience Inc
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Flexus Bioscience Inc
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    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
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    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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