JP6672140B2 - Ｇｌｐ−１化合物の経口投薬 - Google Patents

Ｇｌｐ−１化合物の経口投薬 Download PDF

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Publication number
JP6672140B2
JP6672140B2 JP2016511088A JP2016511088A JP6672140B2 JP 6672140 B2 JP6672140 B2 JP 6672140B2 JP 2016511088 A JP2016511088 A JP 2016511088A JP 2016511088 A JP2016511088 A JP 2016511088A JP 6672140 B2 JP6672140 B2 JP 6672140B2
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peptide
composition
glp
ethoxy
administered
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JP2016519128A (ja
JP2016519128A5 (https=
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フレミング・セイエル・ニールセン
ペル・サウエルバリ
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Novo Nordisk AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2016511088A 2013-05-02 2014-05-02 Ｇｌｐ−１化合物の経口投薬 Active JP6672140B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019235054A JP7576910B2 (ja) 2013-05-02 2019-12-25 Ｇｌｐ－１化合物の経口投薬

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13166205 2013-05-02
EP13166205.8 2013-05-02
PCT/EP2014/058974 WO2014177683A1 (en) 2013-05-02 2014-05-02 Oral dosing of glp-1 compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019235054A Division JP7576910B2 (ja) 2013-05-02 2019-12-25 Ｇｌｐ－１化合物の経口投薬

Publications (3)

Publication Number Publication Date
JP2016519128A JP2016519128A (ja) 2016-06-30
JP2016519128A5 JP2016519128A5 (https=) 2017-06-15
JP6672140B2 true JP6672140B2 (ja) 2020-03-25

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Family Applications (2)

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JP2016511088A Active JP6672140B2 (ja) 2013-05-02 2014-05-02 Ｇｌｐ−１化合物の経口投薬
JP2019235054A Active JP7576910B2 (ja) 2013-05-02 2019-12-25 Ｇｌｐ－１化合物の経口投薬

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Country Status (25)

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US (6) US20160067184A1 (https=)
EP (2) EP2991671B1 (https=)
JP (2) JP6672140B2 (https=)
KR (3) KR102272671B1 (https=)
AU (1) AU2014261336B2 (https=)
BR (1) BR112015026325A2 (https=)
CA (1) CA2910903A1 (https=)
CY (1) CY1120730T1 (https=)
DK (1) DK2991671T3 (https=)
ES (1) ES2688462T3 (https=)
HR (1) HRP20181393T1 (https=)
HU (1) HUE040609T2 (https=)
IL (1) IL241813A (https=)
LT (1) LT2991671T (https=)
MX (3) MX369259B (https=)
MY (1) MY172578A (https=)
PL (1) PL2991671T3 (https=)
PT (1) PT2991671T (https=)
RS (1) RS58039B1 (https=)
RU (1) RU2671406C2 (https=)
SA (1) SA515370075B1 (https=)
SI (1) SI2991671T1 (https=)
SM (1) SMT201800492T1 (https=)
WO (1) WO2014177683A1 (https=)
ZA (2) ZA201507096B (https=)

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