PL2991671T3 - Doustne dawkowanie związków glp-1 - Google Patents

Doustne dawkowanie związków glp-1

Info

Publication number
PL2991671T3
PL2991671T3 PL14721834T PL14721834T PL2991671T3 PL 2991671 T3 PL2991671 T3 PL 2991671T3 PL 14721834 T PL14721834 T PL 14721834T PL 14721834 T PL14721834 T PL 14721834T PL 2991671 T3 PL2991671 T3 PL 2991671T3
Authority
PL
Poland
Prior art keywords
glp
compounds
oral dosing
dosing
oral
Prior art date
Application number
PL14721834T
Other languages
English (en)
Inventor
Flemming Seier Nielsen
Per Sauerberg
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48190381&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2991671(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PL2991671T3 publication Critical patent/PL2991671T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
PL14721834T 2013-05-02 2014-05-02 Doustne dawkowanie związków glp-1 PL2991671T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13166205 2013-05-02
PCT/EP2014/058974 WO2014177683A1 (en) 2013-05-02 2014-05-02 Oral dosing of glp-1 compounds
EP14721834.1A EP2991671B1 (en) 2013-05-02 2014-05-02 Oral dosing of glp-1 compounds

Publications (1)

Publication Number Publication Date
PL2991671T3 true PL2991671T3 (pl) 2019-01-31

Family

ID=48190381

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14721834T PL2991671T3 (pl) 2013-05-02 2014-05-02 Doustne dawkowanie związków glp-1

Country Status (24)

Country Link
US (3) US20160067184A1 (pl)
EP (2) EP3485900A1 (pl)
JP (2) JP6672140B2 (pl)
KR (3) KR20210086717A (pl)
AU (1) AU2014261336B2 (pl)
BR (1) BR112015026325A2 (pl)
CA (1) CA2910903A1 (pl)
CY (1) CY1120730T1 (pl)
DK (1) DK2991671T3 (pl)
ES (1) ES2688462T3 (pl)
HR (1) HRP20181393T1 (pl)
HU (1) HUE040609T2 (pl)
IL (1) IL241813A (pl)
LT (1) LT2991671T (pl)
MX (3) MX369259B (pl)
MY (1) MY172578A (pl)
PL (1) PL2991671T3 (pl)
PT (1) PT2991671T (pl)
RS (1) RS58039B1 (pl)
RU (1) RU2671406C2 (pl)
SA (1) SA515370075B1 (pl)
SI (1) SI2991671T1 (pl)
WO (1) WO2014177683A1 (pl)
ZA (2) ZA201507096B (pl)

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MX355361B (es) 2011-04-12 2018-04-17 Novo Nordisk As Derivados de peptido 1 tipo glucagon (glp-1) doblemente acilados.
EP4331667A2 (en) 2012-03-22 2024-03-06 Novo Nordisk A/S Compositions comprising a delivery agent and preparation thereof
HUE042757T2 (hu) 2012-03-22 2019-07-29 Novo Nordisk As Szállító szert tartalmazó készítmények és elõállításuk
AU2013234496B2 (en) 2012-03-22 2017-07-27 Novo Nordisk A/S Compositions of GLP-1 peptides and preparation thereof
ES2871328T3 (es) 2012-06-20 2021-10-28 Novo Nordisk As Formulación de comprimido que comprende un péptido y un agente de suministro
RU2671406C2 (ru) * 2013-05-02 2018-10-31 Ново Нордиск А/С Пероральная дозированная форма соединений глюкагоноподобного пептида-1
CA2973099C (en) 2015-01-12 2021-09-14 Enteris Biopharma, Inc. Solid oral dosage forms
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
US11196462B2 (en) 2016-02-22 2021-12-07 Qualcomm Incorporated Multi-layer beamforming in millimeter-wave multiple-input/multiple-output systems
TWI783890B (zh) 2017-08-24 2022-11-11 丹麥商諾佛 儂迪克股份有限公司 Glp-1組成物及其用途
WO2019072941A1 (en) * 2017-10-12 2019-04-18 Novo Nordisk A/S SEMAGLUTIDE IN MEDICAL THERAPY
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IL275778B2 (en) 2018-02-02 2023-12-01 Novo Nordisk As Solid compounds that make up glp-1 agonist n-8-2-hydroxybenzoyl salt
TWI829687B (zh) * 2018-05-07 2024-01-21 丹麥商諾佛 儂迪克股份有限公司 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
TW202332688A (zh) 2018-07-23 2023-08-16 美商美國禮來大藥廠 Gip/glp1共促效劑化合物
US11471512B2 (en) * 2019-03-01 2022-10-18 Merck Sharp & Dohme Llc Pharmaceutical compositions of a peptide
US20220395559A1 (en) 2019-11-07 2022-12-15 Novo Nordisk A/S Solid compositions comprising a glp-1 agonist, an sglt2 inhibitor and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid
KR20220143037A (ko) 2020-02-18 2022-10-24 노보 노르디스크 에이/에스 Glp-1 조성물 및 이의 용도
JP2023524695A (ja) 2020-04-29 2023-06-13 ノヴォ ノルディスク アー／エス Ｇｌｐ－１作動薬およびヒスチジンを含む固形組成物
AU2021312323A1 (en) * 2020-07-22 2023-02-02 Novo Nordisk A/S Co-agonists at GLP-1 and GIP receptors suitable for oral delivery
CN116157414A (zh) * 2020-07-22 2023-05-23 诺和诺德股份有限公司 Glp-1和gip受体共激动剂
EP4360645A1 (en) * 2021-06-25 2024-05-01 Gan & Lee Pharmaceuticals Co., Ltd. Pharmaceutical composition containing glp-1 compound
KR20230010571A (ko) 2021-07-12 2023-01-19 한미약품 주식회사 Glp-1 유사체를 함유하는 경구 투여 제형 조성물
WO2023285580A1 (en) 2021-07-15 2023-01-19 Novo Nordisk A/S Tablet comprising a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid
WO2023065231A1 (en) * 2021-10-21 2023-04-27 Guangzhou Dazhou Biomedicine Ltd. Oral delivery of therapeutic agents
WO2023123063A1 (en) * 2021-12-29 2023-07-06 Guangzhou Dazhou Biomedicine Ltd. Oral delivery
TW202330584A (zh) 2022-01-20 2023-08-01 丹麥商諾佛 儂迪克股份有限公司 前藥及其用途
KR20230132256A (ko) 2022-03-08 2023-09-15 이정열 오징어 조획장치
KR20230147981A (ko) 2022-04-15 2023-10-24 이정열 어류 탈취기
KR20230167546A (ko) 2022-06-02 2023-12-11 이정열 어류 탈취기
KR20240018118A (ko) 2022-08-02 2024-02-13 이정열 어류 탈취기
WO2024040356A1 (en) * 2022-08-25 2024-02-29 The University Of British Columbia Mucoadhesive pharmaceutical dosage form for unidirectional release of peptide therapeutic particles

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WO2002048192A2 (en) 2000-12-13 2002-06-20 Eli Lilly And Company Amidated glucagon-like peptide-1
MXPA03005135A (es) * 2000-12-13 2003-12-04 Lilly Co Eli Regimen de tratamiento cronico usando peptidos insulinotropicos similares al glucagon.
RU2332229C2 (ru) 2002-02-20 2008-08-27 Эмисфире Текнолоджис Инк. Способ введения молекул glp-1
AU2003243929B2 (en) 2002-07-04 2009-06-04 Zp Holding Spv K/S GLP-1 and methods for treating diabetes
EP1654004A2 (en) 2003-08-08 2006-05-10 Novo Nordisk A/S Synthesis and application of new structural well defined branched polymers as conjugating agents for peptides
TWI362392B (en) 2005-03-18 2012-04-21 Novo Nordisk As Acylated glp-1 compounds
EP1971362B1 (en) 2005-08-19 2014-12-03 Amylin Pharmaceuticals, LLC Exendin for treating diabetes and reducing body weight
WO2007061434A2 (en) 2005-11-10 2007-05-31 Nastech Pharmaceutical Company Inc. A pharmaceutical formulation of glp-1 and its use for treating a metabolic syndrome
JP2009520693A (ja) 2005-12-08 2009-05-28 エムディーアールエヌエー，インコーポレイテッド 安定化されたエキセンディン製剤の粘膜送達
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JO2945B1 (en) * 2006-09-13 2016-03-15 سميث كلاين بيتشام كوربوريشن Methods of giving prolonged hypoglycemic agents
RU2524150C2 (ru) 2006-09-22 2014-07-27 Ново Нордиск А/С Аналоги инсулина, устойчивые к протеазам
EP2679597A1 (en) 2007-09-05 2014-01-01 Novo Nordisk A/S Glucagon-like peptide-1 derivatives and their pharmaceutical use
US20100317057A1 (en) 2007-12-28 2010-12-16 Novo Nordisk A/S Semi-recombinant preparation of glp-1 analogues
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DK2513140T3 (en) * 2009-12-16 2016-01-18 Novo Nordisk As Double-acylated GLP-1 derivatives
KR20130093470A (ko) * 2010-04-30 2013-08-22 가부시키가이샤산와카가쿠켄큐쇼 생리활성 물질 등의 생체 내 안정성 향상을 위한 펩티드 및 생체 내 안정성이 향상된 생리활성 물질
DK3326620T3 (da) * 2010-12-16 2020-05-25 Novo Nordisk As Faste sammensætninger omfattende en glp-1-agonist og et salt af n-(8-(2- hydroxybenzoyl)amino)caprylsyre
MX355361B (es) 2011-04-12 2018-04-17 Novo Nordisk As Derivados de peptido 1 tipo glucagon (glp-1) doblemente acilados.
WO2013009545A1 (en) 2011-07-08 2013-01-17 Amylin Pharmaceuticals, Inc. Engineered polypeptides having enhanced duration of action with reduced immunogenicity
AU2013234496B2 (en) 2012-03-22 2017-07-27 Novo Nordisk A/S Compositions of GLP-1 peptides and preparation thereof
EP4331667A2 (en) 2012-03-22 2024-03-06 Novo Nordisk A/S Compositions comprising a delivery agent and preparation thereof
ES2871328T3 (es) * 2012-06-20 2021-10-28 Novo Nordisk As Formulación de comprimido que comprende un péptido y un agente de suministro
RU2671406C2 (ru) * 2013-05-02 2018-10-31 Ново Нордиск А/С Пероральная дозированная форма соединений глюкагоноподобного пептида-1

Also Published As

Publication number Publication date
LT2991671T (lt) 2018-09-25
BR112015026325A2 (pt) 2017-07-25
AU2014261336A1 (en) 2015-10-08
IL241813A (en) 2017-12-31
WO2014177683A1 (en) 2014-11-06
MX2015015009A (es) 2016-03-09
US20170312225A1 (en) 2017-11-02
AU2014261336B2 (en) 2019-02-28
JP2016519128A (ja) 2016-06-30
MX2019013123A (es) 2019-12-05
RU2671406C2 (ru) 2018-10-31
MX369259B (es) 2019-11-04
US20160067184A1 (en) 2016-03-10
RU2015147876A (ru) 2017-06-06
ZA201806791B (en) 2019-06-26
CY1120730T1 (el) 2019-12-11
JP6672140B2 (ja) 2020-03-25
US10278923B2 (en) 2019-05-07
MY172578A (en) 2019-12-03
HUE040609T2 (hu) 2019-03-28
SI2991671T1 (sl) 2018-10-30
JP2020073533A (ja) 2020-05-14
MX2018012166A (es) 2020-09-02
EP3485900A1 (en) 2019-05-22
SA515370075B1 (ar) 2017-08-27
KR20180115814A (ko) 2018-10-23
KR102272671B1 (ko) 2021-07-06
CA2910903A1 (en) 2014-11-06
EP2991671B1 (en) 2018-08-15
ZA201507096B (en) 2020-01-29
DK2991671T3 (en) 2018-10-08
ES2688462T3 (es) 2018-11-02
PT2991671T (pt) 2018-11-05
US20190216739A1 (en) 2019-07-18
HRP20181393T1 (hr) 2018-11-02
KR20160002945A (ko) 2016-01-08
EP2991671A1 (en) 2016-03-09
KR20210086717A (ko) 2021-07-08
RS58039B1 (sr) 2019-02-28

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