SI2827845T1 - Sestavki, ki obsegajo dostavno sredstvo in njihova priprava - Google Patents
Sestavki, ki obsegajo dostavno sredstvo in njihova pripravaInfo
- Publication number
- SI2827845T1 SI2827845T1 SI201331386T SI201331386T SI2827845T1 SI 2827845 T1 SI2827845 T1 SI 2827845T1 SI 201331386 T SI201331386 T SI 201331386T SI 201331386 T SI201331386 T SI 201331386T SI 2827845 T1 SI2827845 T1 SI 2827845T1
- Authority
- SI
- Slovenia
- Prior art keywords
- compositions
- preparation
- delivery agent
- delivery
- agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/609—Amides, e.g. salicylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12160742 | 2012-03-22 | ||
US201361748844P | 2013-01-04 | 2013-01-04 | |
EP13153422 | 2013-01-31 | ||
EP13709232.6A EP2827845B1 (en) | 2012-03-22 | 2013-03-15 | Compositions comprising a delivery agent and preparation thereof |
PCT/EP2013/055363 WO2013139695A1 (en) | 2012-03-22 | 2013-03-15 | Compositions comprising a delivery agent and preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2827845T1 true SI2827845T1 (sl) | 2019-04-30 |
Family
ID=49221869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201331386T SI2827845T1 (sl) | 2012-03-22 | 2013-03-15 | Sestavki, ki obsegajo dostavno sredstvo in njihova priprava |
Country Status (11)
Country | Link |
---|---|
US (1) | US10335369B2 (sl) |
EP (3) | EP4331667A3 (sl) |
JP (1) | JP6356660B2 (sl) |
CN (3) | CN104203221A (sl) |
ES (1) | ES2965469T3 (sl) |
HR (1) | HRP20231613T1 (sl) |
HU (1) | HUE064694T2 (sl) |
PL (2) | PL3542790T3 (sl) |
RS (2) | RS58636B1 (sl) |
SI (1) | SI2827845T1 (sl) |
WO (1) | WO2013139695A1 (sl) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2651398T (pt) | 2010-12-16 | 2018-03-09 | Novo Nordisk As | Composições sólidas compreendendo um agonista de glp-1 e um sal de ácido n-(8-(2-hidroxibenzoil)amino) caprílico |
EP3225631B1 (en) | 2011-04-12 | 2019-01-09 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
CN104203221A (zh) | 2012-03-22 | 2014-12-10 | 诺和诺德A/S(股份有限公司) | 包含递送剂的组合物及其制备 |
EP2827885B1 (en) | 2012-03-22 | 2018-08-15 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
PT2827845T (pt) * | 2012-03-22 | 2019-03-29 | Novo Nordisk As | Composições compreendendo um agente de entrega e sua preparação |
WO2013189988A1 (en) | 2012-06-20 | 2013-12-27 | Novo Nordisk A/S | Tablet formulation comprising a peptide and a delivery agent |
AU2014261336B2 (en) | 2013-05-02 | 2019-02-28 | Novo Nordisk A/S | Oral dosing of GLP-1 compounds |
CN104173313B (zh) * | 2014-08-25 | 2017-05-17 | 杭州朱养心药业有限公司 | 利伐沙班片剂药物组合物 |
WO2016115082A1 (en) | 2015-01-12 | 2016-07-21 | Enteris Biopharma, Inc. | Solid oral dosage forms |
CN108883073B (zh) * | 2016-12-30 | 2021-10-08 | 江苏恒瑞医药股份有限公司 | 一种glp-1类似物的药物组合物及其制备方法 |
AR112015A1 (es) | 2017-06-09 | 2019-09-11 | Novo Nordisk As | Composiciones sólidas para administración oral |
SG11202006595RA (en) | 2018-02-02 | 2020-08-28 | Novo Nordisk As | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
TWI829687B (zh) * | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
WO2020152304A1 (en) * | 2019-01-24 | 2020-07-30 | Novo Nordisk A/S | Roller compactor and method of dry granulation using a roller compactor |
CA3144618A1 (en) * | 2019-08-07 | 2021-02-11 | Novo Nordisk A/S | Solid compositions comprising an egf(a) derivative and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid |
CN114340655A (zh) | 2019-09-02 | 2022-04-12 | 诺和诺德股份有限公司 | 生产包含glp-1肽的片剂的方法 |
JP2022547094A (ja) | 2019-09-06 | 2022-11-10 | ノヴォ ノルディスク アー/エス | 医薬組成物における使用のための顆粒の分別のための方法および機器 |
JP2023502004A (ja) | 2019-11-07 | 2023-01-20 | ノヴォ ノルディスク アー/エス | Glp-1作動薬、sglt2阻害剤、およびn-(8-(2-ヒドロキシベンゾイル)アミノ)カプリル酸の塩を含む固形組成物 |
JP2023524695A (ja) | 2020-04-29 | 2023-06-13 | ノヴォ ノルディスク アー/エス | Glp-1作動薬およびヒスチジンを含む固形組成物 |
CN111517980B (zh) * | 2020-05-14 | 2021-02-09 | 台州浦凯医药科技有限公司 | N-[8-(2-羟基苯甲酰基)氨基]辛酸一钾晶型化合物、制备方法及用途 |
JP2023534131A (ja) | 2020-07-22 | 2023-08-08 | ノヴォ ノルディスク アー/エス | 経口送達に好適なglp-1受容体およびgip受容体共作動薬 |
IL299707A (en) * | 2020-07-22 | 2023-03-01 | Novo Nordisk As | Co-agonists for GLP-1 and GIP receptors |
CN113117050B (zh) * | 2021-05-06 | 2022-04-26 | 合肥天汇孵化科技有限公司 | 多肽组合物及其用途 |
BR112023022400A2 (pt) | 2021-05-07 | 2024-01-16 | Lilly Co Eli | Comprimido erodível, método de fabricação e usos do mesmo |
JP2024525377A (ja) * | 2021-07-15 | 2024-07-12 | ノヴォ ノルディスク アー/エス | N-(8-(2-ヒドロキシベンゾイル)アミノ)カプリル酸の塩を含む錠剤 |
AU2022401780A1 (en) * | 2021-12-01 | 2024-07-04 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Pharmaceutical composition of glp-1 and gip receptor dual agonist and use thereof |
TW202330584A (zh) | 2022-01-20 | 2023-08-01 | 丹麥商諾佛 儂迪克股份有限公司 | 前藥及其用途 |
CN114984191B (zh) * | 2022-07-04 | 2022-10-25 | 北京惠之衡生物科技有限公司 | 一种多肽类药物口服递送组合物 |
TW202421645A (zh) | 2022-11-25 | 2024-06-01 | 丹麥商諾佛 儂迪克股份有限公司 | 如glp—1之肽治療劑的口服投與 |
Family Cites Families (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4609675A (en) | 1984-08-17 | 1986-09-02 | The Upjohn Company | Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing |
IE62126B1 (en) | 1986-03-12 | 1994-12-14 | American Cyanamid Co | Macrolide compounds |
DK39892D0 (da) | 1992-03-25 | 1992-03-25 | Bernard Thorens | Peptid |
US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
US5650386A (en) | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
US5866536A (en) | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
PT944648E (pt) | 1996-08-30 | 2007-06-26 | Novo Nordisk As | Derivados do glp-1. |
US5773647A (en) | 1997-02-07 | 1998-06-30 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
AU2610899A (en) | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | N-terminally modified glp-1 derivatives |
AU2610799A (en) | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | Glp-1 derivatives with helix-content exceeding 25 per cent, forming partially structured micellar-like aggregates |
DE69942306D1 (de) | 1998-02-27 | 2010-06-10 | Novo Nordisk As | Abkömmlinge von glp-1 analogen |
JP2003522099A (ja) | 1998-02-27 | 2003-07-22 | ノボ ノルディスク アクティーゼルスカブ | 遅延作用プロファイルを有するglp−1のglp−1誘導体及びエキセンジン |
SE9802080D0 (sv) | 1998-06-11 | 1998-06-11 | Hellstroem | Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein |
EP1149066B1 (en) | 1999-02-05 | 2005-11-09 | Emisphere Technologies, Inc. | Method of preparing alkylated salicylamides |
DE60038097T2 (de) | 1999-02-22 | 2009-02-12 | Merrion Research I Ltd. | Feste orale dosierungsform enthaltend einen resorptionsverstärker |
AU3240900A (en) | 1999-02-22 | 2000-09-04 | Emisphere Holdings, Inc. | Solid oral dosage form containing heparin or a heparinoid in combination with a carrier |
US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
GB9923436D0 (en) | 1999-10-04 | 1999-12-08 | American Home Prod | Pharmaceutical compositions |
US6793934B1 (en) | 1999-12-08 | 2004-09-21 | Shire Laboratories, Inc. | Solid oral dosage form |
AU2001275231A1 (en) | 2000-06-02 | 2001-12-11 | Emisphere Technologies, Inc. | Method of preparing salicylamides |
US7049283B2 (en) | 2000-12-06 | 2006-05-23 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
CA2442280A1 (en) | 2001-03-27 | 2002-10-03 | Ranbaxy Laboratories Limited | A stable pharmaceutical composition of pravastatin |
CN1527700A (zh) | 2001-05-15 | 2004-09-08 | ��������ʲ��������ι�˾ | 制备苯妥英钠剂型的压缩方法 |
US20030068356A1 (en) | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
EP1461031B1 (en) | 2001-11-29 | 2016-06-29 | Emisphere Technologies, Inc. | Formulations for oral administration of cromolyn sodium |
BR0307331A (pt) | 2002-02-01 | 2004-12-07 | Pfizer Prod Inc | Formulações granuladas a seco de azitromicina |
WO2003072195A2 (en) | 2002-02-20 | 2003-09-04 | Eli Lilly And Company | Method for administering glp-1 molecules |
JP2004131398A (ja) * | 2002-10-08 | 2004-04-30 | Taihei Chemical Industrial Co Ltd | 錠剤用滑沢剤 |
BRPI0411165A (pt) | 2003-05-14 | 2006-07-11 | Emisphere Tech Inc | composição farmacêutica, forma de unidade de dosagem e métodos para preparar seu uso |
JP5032844B2 (ja) | 2003-07-11 | 2012-09-26 | ノバルティス アーゲー | 微粉末形態の送達物質を含む経口投与用医薬組成物 |
BRPI0414539B8 (pt) | 2003-09-19 | 2021-05-25 | Novo Nordisk As | composto, composição farmacêutica, e, uso de um composto |
JP2007537141A (ja) | 2003-12-18 | 2007-12-20 | ノボ ノルディスク アクティーゼルスカブ | 新規なglp−1化合物 |
KR20060109940A (ko) | 2003-12-18 | 2006-10-23 | 노보 노르디스크 에이/에스 | 알부민-유사제에 연결된 신규 glp-1 유사체 |
US20060286129A1 (en) | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
WO2005099672A1 (en) | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | A modified release pharmaceutical formulation comprising amoxicillin and clavulanate |
RU2006138703A (ru) * | 2004-05-06 | 2008-06-20 | Эмисфире Текнолоджис | Твердая лекарственная форма увлажненного гепарина |
WO2005107462A2 (en) | 2004-05-06 | 2005-11-17 | Emisphere Technologies, Inc. | Crystalline polymorphic forms of monosodium n-[8-(2-hydroxybenzoyl)amino]caprylate |
US8273794B2 (en) | 2004-05-14 | 2012-09-25 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
WO2005115347A1 (en) | 2004-05-31 | 2005-12-08 | Sam-A Pharmaceuticals Co., Ltd. | Dispersible tablet comprising beta lactam antibiotics and process for preparing the same |
CN101010339B (zh) | 2004-07-02 | 2011-11-09 | 布里斯托尔-迈尔斯斯奎布公司 | 人类胰高血糖素样肽-1调节剂及它们在治疗糖尿病及相关病况中的用途 |
AU2005261740A1 (en) | 2004-07-08 | 2006-01-19 | Novo Nordisk A/S | Polypeptide protracting tags comprising a tetrazole moiety |
US20060078622A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
EP1799710A2 (en) | 2004-10-07 | 2007-06-27 | Novo Nordisk A/S | Protracted glp-1 compounds |
JP5107713B2 (ja) | 2004-10-07 | 2012-12-26 | ノヴォ ノルディスク アー/エス | 遅延性のエキセンディン−4化合物 |
ES2755273T3 (es) | 2004-12-03 | 2020-04-22 | Merck Sharp & Dohme | Formulación farmacéutica de inhibidores de la carboxamida VIH integrasa que contienen una composición de control de la velocidad de liberación |
ES2540929T3 (es) | 2005-02-01 | 2015-07-14 | Emisphere Technologies, Inc. | Sistema de administración de retención gástrica y liberación controlada |
MX2007011307A (es) | 2005-03-18 | 2007-10-08 | Novo Nordisk As | Compuestos de glp-1 extendidos. |
TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
EP1863449A2 (en) | 2005-03-28 | 2007-12-12 | Dexcel Pharma Technologies Ltd. | Controlled absorption of statins in the intestine |
US20070049557A1 (en) | 2005-08-24 | 2007-03-01 | Hashim Ahmed | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers |
JP2009515993A (ja) | 2005-11-17 | 2009-04-16 | ノバルティス アクチエンゲゼルシャフト | 医薬組成物 |
MX2008012678A (es) | 2006-04-07 | 2008-12-17 | Merrion Res Iii Ltd | Forma de dosis oral solida que contiene un mejorador. |
US8927015B2 (en) | 2006-04-12 | 2015-01-06 | Emisphere Technologies, Inc. | Formulations for delivering insulin |
CA2654566A1 (en) | 2006-06-09 | 2007-12-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
WO2008003050A2 (en) * | 2006-06-28 | 2008-01-03 | Emisphere Technologies, Inc. | Gallium nitrate formulations |
ES2296529B1 (es) | 2006-08-07 | 2009-04-01 | Laboratorios Farmaceuticos Rovi, S.A. | Composicion farmaceutica con promotores de absorcion. |
WO2008023050A1 (en) | 2006-08-25 | 2008-02-28 | Novo Nordisk A/S | Acylated exendin-4 compounds |
AU2007293916B2 (en) | 2006-09-07 | 2011-02-03 | Emisphere Technologies, Inc. | A process for the manufacture of SNAC (salcaprozate sodium) |
PE20080845A1 (es) | 2006-09-22 | 2008-08-13 | Novartis Ag | Metodo para fabricar tabletas que contienen agentes farmacologicamente activos |
US20100069410A1 (en) * | 2006-12-01 | 2010-03-18 | Emisphere Technologies Inc. | acyclovir formulations |
EP2131810B1 (en) | 2007-03-02 | 2011-05-04 | Novartis AG | Oral administration of a calcitonin |
WO2009032749A2 (en) | 2007-08-29 | 2009-03-12 | The Regents Of The University Of Californina | Salicylanilide modified peptides for use as oral therapeutics |
WO2009030771A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
JP2010538049A (ja) | 2007-09-05 | 2010-12-09 | ノボ・ノルデイスク・エー/エス | 切断型glp−1誘導体及びその治療的使用 |
US8895694B2 (en) | 2007-09-05 | 2014-11-25 | Novo Nordisk A/S | Glucagon-Like Peptide-1 derivatives and their pharmaceutical use |
CN101939023B (zh) | 2007-10-16 | 2016-08-03 | 百康有限公司 | 可经口给药的固体药物组合物及其方法 |
WO2009059188A1 (en) | 2007-11-02 | 2009-05-07 | Emisphere Technologies, Inc. | Method of treating vitamin b12 deficiency |
US20090124639A1 (en) | 2007-11-06 | 2009-05-14 | Emisphere Technologies Inc. | valacyclovir formulations |
US20100317057A1 (en) * | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
EP3741359A1 (en) * | 2008-08-18 | 2020-11-25 | Entera Bio Ltd. | Methods and compositions for oral administration of proteins |
CA2752437C (en) | 2009-02-13 | 2017-07-11 | Boehringer Ingelheim International Gmbh | Antidiabetic medications |
AU2010339907A1 (en) | 2009-12-16 | 2012-07-05 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
US20110182985A1 (en) | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
WO2011109787A1 (en) | 2010-03-05 | 2011-09-09 | Conjuchem, Llc | Methods of administering insulinotropic peptides |
WO2011116139A2 (en) | 2010-03-16 | 2011-09-22 | Chiasma Inc. | Improved pharmaceutical compositions and methods of delivery |
EP3150198B1 (en) | 2010-04-07 | 2021-09-22 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyriodin-2-yl)benzoic acid and administration thereof |
CN102946875A (zh) | 2010-05-05 | 2013-02-27 | 贝林格尔.英格海姆国际有限公司 | 组合疗法 |
DE202010015867U1 (de) | 2010-11-25 | 2011-05-05 | Buchhalter, Thomas | Elektromechanische Halterung zur Aufnahme von Navigations- und Kommunikationsgeräte im KFZ |
PT2651398T (pt) | 2010-12-16 | 2018-03-09 | Novo Nordisk As | Composições sólidas compreendendo um agonista de glp-1 e um sal de ácido n-(8-(2-hidroxibenzoil)amino) caprílico |
CN104203221A (zh) | 2012-03-22 | 2014-12-10 | 诺和诺德A/S(股份有限公司) | 包含递送剂的组合物及其制备 |
EP2827885B1 (en) | 2012-03-22 | 2018-08-15 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
WO2013189988A1 (en) | 2012-06-20 | 2013-12-27 | Novo Nordisk A/S | Tablet formulation comprising a peptide and a delivery agent |
AU2014261336B2 (en) | 2013-05-02 | 2019-02-28 | Novo Nordisk A/S | Oral dosing of GLP-1 compounds |
-
2013
- 2013-03-15 CN CN201380015235.1A patent/CN104203221A/zh active Pending
- 2013-03-15 PL PL18212576.5T patent/PL3542790T3/pl unknown
- 2013-03-15 HU HUE18212576A patent/HUE064694T2/hu unknown
- 2013-03-15 CN CN202010243609.7A patent/CN111494323B/zh active Active
- 2013-03-15 SI SI201331386T patent/SI2827845T1/sl unknown
- 2013-03-15 CN CN202010243610.XA patent/CN111494324B/zh active Active
- 2013-03-15 EP EP23195317.5A patent/EP4331667A3/en active Pending
- 2013-03-15 JP JP2015500854A patent/JP6356660B2/ja active Active
- 2013-03-15 EP EP18212576.5A patent/EP3542790B1/en active Active
- 2013-03-15 HR HRP20231613TT patent/HRP20231613T1/hr unknown
- 2013-03-15 EP EP13709232.6A patent/EP2827845B1/en active Active
- 2013-03-15 US US14/386,218 patent/US10335369B2/en active Active
- 2013-03-15 RS RS20190386A patent/RS58636B1/sr unknown
- 2013-03-15 WO PCT/EP2013/055363 patent/WO2013139695A1/en active Application Filing
- 2013-03-15 PL PL13709232T patent/PL2827845T3/pl unknown
- 2013-03-15 ES ES18212576T patent/ES2965469T3/es active Active
- 2013-03-15 RS RS20231190A patent/RS64942B1/sr unknown
Also Published As
Publication number | Publication date |
---|---|
EP3542790B1 (en) | 2023-09-13 |
RS58636B1 (sr) | 2019-05-31 |
RS64942B1 (sr) | 2024-01-31 |
JP6356660B2 (ja) | 2018-07-11 |
EP2827845A1 (en) | 2015-01-28 |
PL3542790T3 (pl) | 2024-02-26 |
HRP20231613T1 (hr) | 2024-03-15 |
CN104203221A (zh) | 2014-12-10 |
CN111494324B (zh) | 2023-05-16 |
US10335369B2 (en) | 2019-07-02 |
EP4331667A2 (en) | 2024-03-06 |
HUE064694T2 (hu) | 2024-04-28 |
ES2965469T3 (es) | 2024-04-15 |
WO2013139695A1 (en) | 2013-09-26 |
EP3542790C0 (en) | 2023-09-13 |
EP3542790A1 (en) | 2019-09-25 |
JP2015515459A (ja) | 2015-05-28 |
CN111494323B (zh) | 2023-03-28 |
CN111494323A (zh) | 2020-08-07 |
CN111494324A (zh) | 2020-08-07 |
US20150031606A1 (en) | 2015-01-29 |
EP4331667A3 (en) | 2024-05-08 |
EP2827845B1 (en) | 2018-12-26 |
PL2827845T3 (pl) | 2019-06-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUE064694T2 (hu) | Továbbítószert tartalmazó készítmények és elõállításuk | |
IL286348A (en) | Pharmaceutical preparations that include allopregnanolone | |
IL253870B (en) | Certain amino-pyrimidines and pharmaceutical preparations containing them | |
ZA201703992B (en) | Inhalable pharmaceutical compositions | |
HRP20190489T1 (hr) | Pripravci koji sadrže sredstvo za unošenje i njihova priprava | |
IL252566A0 (en) | Pharmacy preparations and methods | |
HK1195793A1 (zh) | 結合藥物組合物及其用途 | |
HK1201152A1 (en) | Dermal delivery compositions and methods | |
IL236268A0 (en) | Preparations for mucosal administration and their uses | |
IL236358B (en) | Medicinal preparations containing hormone replacements and their use | |
IL236024A (en) | The history of benzimidazole-proline and its pharmaceutical preparations | |
EP2775831A4 (en) | PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | |
EP2753341A4 (en) | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | |
EP2668044A4 (en) | COMPOSITIONS AND THEIR USE | |
PL2908837T3 (pl) | Kompozycje do dostarczania leku | |
ZA201307837B (en) | Compositions comprising antibacterial agent and tazobactam | |
ZA201504512B (en) | Pharmaceutical composition comprising desloratadine and prednisolone and use thereof | |
GB201208315D0 (en) | Pharmaceutical methods and compositions | |
EP2926811A4 (en) | ARTEMISCULAR PHARMACEUTICAL COMPOSITION, MANUFACTURE AND USE | |
EP2834635A4 (en) | COMPOSITIONS WITH A HEPARINE ACCUMULATIVE AND METHOD THEREFOR | |
EP2838365A4 (en) | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | |
GB201219884D0 (en) | New composition and preparation thereof | |
GB201110598D0 (en) | Pharmaceutical compositions and devices |