JP6620096B2 - ピラノクロメニルフェノール誘導体、及び代謝症候群または炎症疾患治療用医薬組成物 - Google Patents
ピラノクロメニルフェノール誘導体、及び代謝症候群または炎症疾患治療用医薬組成物 Download PDFInfo
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- JP6620096B2 JP6620096B2 JP2016540481A JP2016540481A JP6620096B2 JP 6620096 B2 JP6620096 B2 JP 6620096B2 JP 2016540481 A JP2016540481 A JP 2016540481A JP 2016540481 A JP2016540481 A JP 2016540481A JP 6620096 B2 JP6620096 B2 JP 6620096B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20130162909 | 2013-12-24 | ||
| KR10-2013-0162909 | 2013-12-24 | ||
| KR1020140181951A KR102344479B1 (ko) | 2013-12-24 | 2014-12-17 | 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물 |
| KR10-2014-0181951 | 2014-12-17 | ||
| PCT/KR2014/012688 WO2015099392A1 (ko) | 2013-12-24 | 2014-12-23 | 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018056783A Division JP2018135343A (ja) | 2013-12-24 | 2018-03-23 | ピラノクロメニルフェノール誘導体、及び代謝症候群または炎症疾患治療用医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017501163A JP2017501163A (ja) | 2017-01-12 |
| JP6620096B2 true JP6620096B2 (ja) | 2019-12-11 |
Family
ID=53788040
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540481A Active JP6620096B2 (ja) | 2013-12-24 | 2014-12-23 | ピラノクロメニルフェノール誘導体、及び代謝症候群または炎症疾患治療用医薬組成物 |
| JP2018056783A Pending JP2018135343A (ja) | 2013-12-24 | 2018-03-23 | ピラノクロメニルフェノール誘導体、及び代謝症候群または炎症疾患治療用医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018056783A Pending JP2018135343A (ja) | 2013-12-24 | 2018-03-23 | ピラノクロメニルフェノール誘導体、及び代謝症候群または炎症疾患治療用医薬組成物 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9783551B2 (enExample) |
| EP (1) | EP3098224B1 (enExample) |
| JP (2) | JP6620096B2 (enExample) |
| KR (1) | KR102344479B1 (enExample) |
| CN (1) | CN105849111B (enExample) |
| AU (1) | AU2014370697B2 (enExample) |
| BR (1) | BR112016011281B1 (enExample) |
| CA (1) | CA2929001C (enExample) |
| CY (1) | CY1121554T1 (enExample) |
| DK (1) | DK3098224T3 (enExample) |
| ES (1) | ES2718878T3 (enExample) |
| HR (1) | HRP20190573T1 (enExample) |
| HU (1) | HUE043902T2 (enExample) |
| IL (1) | IL245908B (enExample) |
| MX (1) | MX374944B (enExample) |
| NZ (1) | NZ720328A (enExample) |
| PL (1) | PL3098224T3 (enExample) |
| PT (1) | PT3098224T (enExample) |
| SG (1) | SG11201604371PA (enExample) |
| TW (1) | TWI585093B (enExample) |
| WO (1) | WO2015099392A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102344479B1 (ko) * | 2013-12-24 | 2021-12-29 | 주식회사 글라세움 | 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물 |
| TWI731998B (zh) | 2016-06-29 | 2021-07-01 | 南韓商格雷森伍股份有限公司 | 光學活性吡喃並苯並吡喃基苯酚衍生物及包含其的醫藥組成物 |
| TWI641610B (zh) * | 2016-10-04 | 2018-11-21 | 南韓商格雷森伍股份有限公司 | 用於合成3-苯基-2,3,4,8,9,10-六氫吡喃並[2,3-f]色烯衍生物及其光學異構物的方法 |
| TWI804600B (zh) * | 2018-04-03 | 2023-06-11 | 南韓商格雷森伍股份有限公司 | 3-苯基-2,8-二氫吡喃[2,3-ƒ]苯并哌喃衍生物的合成方法 |
| WO2019194583A1 (ko) * | 2018-04-03 | 2019-10-10 | 주식회사 글라세움 | 3-페닐-2,8-디히드로피라노[2,3-f]크로멘 유도체 및 이를 포함하는 약학적 조성물 |
| KR20200105198A (ko) * | 2019-02-28 | 2020-09-07 | 주식회사 글라세움 | 신경계 질환의 예방 또는 치료용 약학적 조성물 |
| KR102692932B1 (ko) | 2019-07-30 | 2024-08-07 | 주식회사 글라세움 | 2-((6-(히드록시메틸)크로멘-5-일)옥시)-1-페닐에타논 유도체의 합성 방법 |
| US20250367163A1 (en) | 2021-06-08 | 2025-12-04 | Glaceum, Inc. | Pharmaceutical composition for preventing or treating degenerative eye diseases |
| CN113616548B (zh) * | 2021-09-02 | 2023-04-28 | 河南科技大学 | 一种水溶性光甘草定包合物及其制备方法 |
| CN119343351A (zh) | 2022-04-12 | 2025-01-21 | 格拉斯如睦株式会社 | 用于3-苯基-2,3,4,8,9,10-六氢吡喃并[2,3-f]色烯衍生物的合成方法 |
| CN114903879B (zh) * | 2022-06-23 | 2023-10-31 | 东北大学 | 3-烃基苯酚衍生物在制备预防或治疗高脂血症及相关代谢性疾病产品中的用途 |
| KR20240113389A (ko) | 2023-01-12 | 2024-07-22 | 주식회사 글라세움 | 퇴행성 골관절염의 예방 또는 치료용 약학적 조성물 |
| KR20250081177A (ko) | 2023-11-29 | 2025-06-05 | 한국화학연구원 | Hsg4112 r형을 유효성분으로 포함하는 반려동물의 비만 예방, 개선 또는 치료용 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050035142A (ko) * | 2001-10-11 | 2005-04-15 | 카네카 코포레이션 | 페록시좀 증식제 응답성 수용체 리간드제 및 그 제조 방법 |
| KR100565423B1 (ko) * | 2003-10-20 | 2006-03-30 | 빅 바이오 주식회사 | 이소플라반 유도체 또는 이소플라벤 유도체의 제조방법 |
| JP2006008604A (ja) * | 2004-06-25 | 2006-01-12 | Kuraray Co Ltd | イソフラバン誘導体の製造方法 |
| WO2007058480A1 (en) | 2005-11-16 | 2007-05-24 | Md Bioalpha Co., Ltd. | Composition having effect on treatment and prevention of diseases syndrome treatment with glabridin |
| KR102344479B1 (ko) * | 2013-12-24 | 2021-12-29 | 주식회사 글라세움 | 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물 |
-
2014
- 2014-12-17 KR KR1020140181951A patent/KR102344479B1/ko active Active
- 2014-12-23 CA CA2929001A patent/CA2929001C/en active Active
- 2014-12-23 MX MX2016008429A patent/MX374944B/es active IP Right Grant
- 2014-12-23 EP EP14873860.2A patent/EP3098224B1/en active Active
- 2014-12-23 PL PL14873860T patent/PL3098224T3/pl unknown
- 2014-12-23 HR HRP20190573TT patent/HRP20190573T1/hr unknown
- 2014-12-23 AU AU2014370697A patent/AU2014370697B2/en active Active
- 2014-12-23 PT PT14873860T patent/PT3098224T/pt unknown
- 2014-12-23 US US15/037,230 patent/US9783551B2/en active Active
- 2014-12-23 BR BR112016011281-4A patent/BR112016011281B1/pt active IP Right Grant
- 2014-12-23 SG SG11201604371PA patent/SG11201604371PA/en unknown
- 2014-12-23 HU HUE14873860 patent/HUE043902T2/hu unknown
- 2014-12-23 ES ES14873860T patent/ES2718878T3/es active Active
- 2014-12-23 WO PCT/KR2014/012688 patent/WO2015099392A1/ko not_active Ceased
- 2014-12-23 JP JP2016540481A patent/JP6620096B2/ja active Active
- 2014-12-23 NZ NZ720328A patent/NZ720328A/en unknown
- 2014-12-23 CN CN201480070935.5A patent/CN105849111B/zh active Active
- 2014-12-23 DK DK14873860.2T patent/DK3098224T3/da active
- 2014-12-24 TW TW103145316A patent/TWI585093B/zh active
-
2016
- 2016-05-29 IL IL245908A patent/IL245908B/en active IP Right Grant
-
2018
- 2018-03-23 JP JP2018056783A patent/JP2018135343A/ja active Pending
-
2019
- 2019-04-16 CY CY20191100423T patent/CY1121554T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN105849111A (zh) | 2016-08-10 |
| KR102344479B1 (ko) | 2021-12-29 |
| PL3098224T3 (pl) | 2019-07-31 |
| NZ720328A (en) | 2018-02-23 |
| ES2718878T3 (es) | 2019-07-05 |
| PT3098224T (pt) | 2019-04-26 |
| MX2016008429A (es) | 2017-02-23 |
| DK3098224T3 (da) | 2019-05-13 |
| CN105849111B (zh) | 2018-05-04 |
| HUE043902T2 (hu) | 2019-10-28 |
| JP2018135343A (ja) | 2018-08-30 |
| BR112016011281B1 (pt) | 2021-11-16 |
| AU2014370697B2 (en) | 2017-01-19 |
| US9783551B2 (en) | 2017-10-10 |
| EP3098224A4 (en) | 2017-07-05 |
| US20160272650A1 (en) | 2016-09-22 |
| SG11201604371PA (en) | 2016-07-28 |
| IL245908B (en) | 2020-08-31 |
| EP3098224A1 (en) | 2016-11-30 |
| KR20150075030A (ko) | 2015-07-02 |
| BR112016011281A2 (enExample) | 2017-08-08 |
| MX374944B (es) | 2025-03-06 |
| JP2017501163A (ja) | 2017-01-12 |
| EP3098224B1 (en) | 2019-01-30 |
| CA2929001C (en) | 2018-02-20 |
| TW201607949A (zh) | 2016-03-01 |
| HRP20190573T1 (hr) | 2019-05-17 |
| IL245908A0 (en) | 2016-08-02 |
| CY1121554T1 (el) | 2020-05-29 |
| AU2014370697A1 (en) | 2016-06-16 |
| WO2015099392A1 (ko) | 2015-07-02 |
| CA2929001A1 (en) | 2015-07-02 |
| TWI585093B (zh) | 2017-06-01 |
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