JP6330024B2 - 生体吸収性バイオメディカルインプラント - Google Patents

生体吸収性バイオメディカルインプラント Download PDF

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Publication number
JP6330024B2
JP6330024B2 JP2016501719A JP2016501719A JP6330024B2 JP 6330024 B2 JP6330024 B2 JP 6330024B2 JP 2016501719 A JP2016501719 A JP 2016501719A JP 2016501719 A JP2016501719 A JP 2016501719A JP 6330024 B2 JP6330024 B2 JP 6330024B2
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JP
Japan
Prior art keywords
polymer
rapamycin
mpa
tubular scaffold
average
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2016501719A
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English (en)
Japanese (ja)
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JP2016517311A (ja
Inventor
マクレイン,ジェイムズ・ビー
テイラー,チャールズ・ダグラス
バーガーマイスター,ロバート・スティーヴン
Original Assignee
マイセル・テクノロジーズ,インコーポレイテッド
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Expired - Fee Related legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0035Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in release or diffusion time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polymers & Plastics (AREA)
JP2016501719A 2013-03-12 2014-03-12 生体吸収性バイオメディカルインプラント Expired - Fee Related JP6330024B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361777230P 2013-03-12 2013-03-12
US61/777,230 2013-03-12
PCT/US2014/025017 WO2014165264A1 (en) 2013-03-12 2014-03-12 Bioabsorbable biomedical implants

Publications (2)

Publication Number Publication Date
JP2016517311A JP2016517311A (ja) 2016-06-16
JP6330024B2 true JP6330024B2 (ja) 2018-05-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016501719A Expired - Fee Related JP6330024B2 (ja) 2013-03-12 2014-03-12 生体吸収性バイオメディカルインプラント

Country Status (10)

Country Link
US (1) US11039943B2 (zh)
EP (1) EP2967803B1 (zh)
JP (1) JP6330024B2 (zh)
KR (1) KR20150143476A (zh)
CN (2) CN105307597A (zh)
AU (1) AU2014248508B2 (zh)
CA (1) CA2905419C (zh)
HK (1) HK1220602A1 (zh)
IL (1) IL241421B (zh)
WO (1) WO2014165264A1 (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
EP1909973B1 (en) 2005-07-15 2018-08-22 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
US8852625B2 (en) 2006-04-26 2014-10-07 Micell Technologies, Inc. Coatings containing multiple drugs
CN101711137B (zh) 2007-01-08 2014-10-22 米歇尔技术公司 具有可生物降解层的支架
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
US9433516B2 (en) 2007-04-17 2016-09-06 Micell Technologies, Inc. Stents having controlled elution
CA2721832C (en) 2008-04-17 2018-08-07 Micell Technologies, Inc. Stents having bioabsorbable layers
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
JP2011528275A (ja) 2008-07-17 2011-11-17 ミセル テクノロジーズ,インク. 薬物送達医療デバイス
CN102481195B (zh) 2009-04-01 2015-03-25 米歇尔技术公司 涂覆支架
EP2531140B1 (en) 2010-02-02 2017-11-01 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
EP2593039B1 (en) 2010-07-16 2022-11-30 Micell Technologies, Inc. Drug delivery medical device
CA2841360A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
WO2014165264A1 (en) 2013-03-12 2014-10-09 Micell Technologies, Inc. Bioabsorbable biomedical implants
KR102079613B1 (ko) 2013-05-15 2020-02-20 미셀 테크놀로지즈, 인코포레이티드 생흡수성 생체의학적 임플란트
DE102015115279A1 (de) 2015-09-10 2017-03-16 Bentley Innomed Gmbh Expandierbare Gefäßstütze
WO2018036434A1 (zh) * 2016-08-23 2018-03-01 深圳市信立泰生物医疗工程有限公司 一种植入式完全生物可吸收血管聚合物支架
WO2018081463A1 (en) * 2016-10-26 2018-05-03 University Of Pittsburgh -Of The Commonwealth System Of Higher Education Calcineurin inhibitor and non-steroidal anti-inflammatory drug to reduce risk of post-imaging pancreatitis
CN106726005B (zh) * 2017-02-22 2018-05-01 南京市第一医院 一种治疗冠脉介入穿孔的可吸收覆膜支架
JP2021074027A (ja) * 2018-03-13 2021-05-20 テルモ株式会社 ステントおよびステントの作製方法
KR102102660B1 (ko) * 2019-09-03 2020-04-22 (주)티제이테크 말초혈관용 스텐트의 코팅 조성액 제조 및 코팅 방법
KR102407468B1 (ko) * 2021-11-30 2022-06-10 주식회사 파인트코리아 스텐트 제조용 생분해성 복합소재 조성물 및 이의 제조 방법

Family Cites Families (610)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123077A (en) 1964-03-03 Surgical suture
US3087860A (en) 1958-12-19 1963-04-30 Abbott Lab Method of prolonging release of drug from a precompressed solid carrier
US3457280A (en) 1967-06-12 1969-07-22 American Cyanamid Co Alpha-glycolide and methods for the isolation thereof
US3597449A (en) 1967-11-16 1971-08-03 American Cyanamid Co Stable glycolide and lactide composition
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
DE2010115A1 (de) 1970-03-04 1971-09-16 Farbenfabriken Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Mikrogranulaten
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US4000137A (en) 1975-06-10 1976-12-28 American Home Products Corporation Antitumor derivatives of periodate-oxidized nucleosides
US4188373A (en) 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4285987A (en) 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
JPS5668674A (en) 1979-11-08 1981-06-09 Shionogi & Co Ltd 5-fluorouracil derivative
US4326532A (en) 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
US4389330A (en) 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4675189A (en) 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
US4474572A (en) 1981-09-29 1984-10-02 Syntex (U.S.A.) Inc. Implanting device and implant magazine
SE445884B (sv) 1982-04-30 1986-07-28 Medinvent Sa Anordning for implantation av en rorformig protes
US4530840A (en) 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
SE435444B (sv) 1983-02-25 1984-10-01 Hakan Johansson Fiskeredskap med en fangstlina som utgores av en ljusledare
US4606347A (en) 1983-03-25 1986-08-19 Thomas J. Fogarty Inverted balloon catheter having sealed through lumen
US4478822A (en) 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4734227A (en) 1983-09-01 1988-03-29 Battelle Memorial Institute Method of making supercritical fluid molecular spray films, powder and fibers
US4734451A (en) 1983-09-01 1988-03-29 Battelle Memorial Institute Supercritical fluid molecular spray thin films and fine powders
US4582731A (en) 1983-09-01 1986-04-15 Battelle Memorial Institute Supercritical fluid molecular spray film deposition and powder formation
US6309669B1 (en) 1984-03-16 2001-10-30 The United States Of America As Represented By The Secretary Of The Army Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US5102417A (en) 1985-11-07 1992-04-07 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4985625A (en) 1986-03-06 1991-01-15 Finnigan Corporation Transfer line for mass spectrometer apparatus
US4762593A (en) 1986-06-13 1988-08-09 Youngner Philip G Distilling apparatus
US4758435A (en) 1986-08-11 1988-07-19 American Cyanamid Company Estradiol implant composition and method for preparation
US5106650A (en) 1988-07-14 1992-04-21 Union Carbide Chemicals & Plastics Technology Corporation Electrostatic liquid spray application of coating with supercritical fluids as diluents and spraying from an orifice
US4950239A (en) 1988-08-09 1990-08-21 Worldwide Medical Plastics Inc. Angioplasty balloons and balloon catheters
EP0431046B1 (en) 1988-08-24 1995-05-03 SLEPIAN, Marvin J. Biodegradable polymeric endoluminal sealing
US4931037A (en) 1988-10-13 1990-06-05 International Medical, Inc. In-dwelling ureteral stent and injection stent assembly, and method of using same
US4958625A (en) 1989-07-18 1990-09-25 Boston Scientific Corporation Biopsy needle instrument
ES2043289T3 (es) 1989-09-25 1993-12-16 Schneider Usa Inc La extrusion de capas multiples como procedimiento para hacer balones de angioplastia.
CA2026604A1 (en) 1989-10-02 1991-04-03 Rodney G. Wolff Articulated stent
US5000519A (en) 1989-11-24 1991-03-19 John Moore Towed vehicle emergency brake control system
US5674192A (en) 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
JP2641781B2 (ja) 1990-02-23 1997-08-20 シャープ株式会社 半導体素子分離領域の形成方法
US5545208A (en) 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5360403A (en) 1990-05-16 1994-11-01 Lake Region Manufacturing Co., Inc. Balloon catheter with lumen occluder
WO1991017724A1 (en) 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
US5320634A (en) 1990-07-03 1994-06-14 Interventional Technologies, Inc. Balloon catheter with seated cutting edges
US5090419A (en) 1990-08-23 1992-02-25 Aubrey Palestrant Apparatus for acquiring soft tissue biopsy specimens
US6248129B1 (en) 1990-09-14 2001-06-19 Quanam Medical Corporation Expandable polymeric stent with memory and delivery apparatus and method
US6524698B1 (en) 1990-09-27 2003-02-25 Helmuth Schmoock Fluid impermeable foil
CA2060635A1 (en) 1991-02-12 1992-08-13 Keith D'alessio Bioabsorbable medical implants
GB2253164B (en) 1991-02-22 1994-10-05 Hoechst Uk Ltd Improvements in or relating to electrostatic coating of substrates of medicinal products
US5158986A (en) 1991-04-05 1992-10-27 Massachusetts Institute Of Technology Microcellular thermoplastic foamed with supercritical fluid
US5195969A (en) 1991-04-26 1993-03-23 Boston Scientific Corporation Co-extruded medical balloons and catheter using such balloons
US5372676A (en) 1991-05-15 1994-12-13 Lowe; Michael Method for producing replicated paving stone
US5185776A (en) 1991-08-05 1993-02-09 Townsend Boyd E Cover for an x-ray cassette
US5356433A (en) 1991-08-13 1994-10-18 Cordis Corporation Biocompatible metal surfaces
US5243023A (en) 1991-08-28 1993-09-07 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Polyimides containing amide and perfluoroisopropylidene connecting groups
US5366504A (en) 1992-05-20 1994-11-22 Boston Scientific Corporation Tubular medical prosthesis
JPH0698902A (ja) 1991-11-22 1994-04-12 Janome Sewing Mach Co Ltd 骨インプラントの製造方法
US5125570A (en) 1991-12-30 1992-06-30 Robert Jones Delivery box signal device
US5697882A (en) 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
WO1993019803A1 (en) 1992-03-31 1993-10-14 Boston Scientific Corporation Medical wire
US5288711A (en) 1992-04-28 1994-02-22 American Home Products Corporation Method of treating hyperproliferative vascular disease
US5342621A (en) 1992-09-15 1994-08-30 Advanced Cardiovascular Systems, Inc. Antithrombogenic surface
US5500180A (en) 1992-09-30 1996-03-19 C. R. Bard, Inc. Method of making a distensible dilatation balloon using a block copolymer
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5387313A (en) 1992-11-09 1995-02-07 Bmc Industries, Inc. Etchant control system
US5385776A (en) 1992-11-16 1995-01-31 Alliedsignal Inc. Nanocomposites of gamma phase polymers containing inorganic particulate material
EP0604022A1 (en) 1992-12-22 1994-06-29 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method for its manufacture
US5324049A (en) 1992-12-23 1994-06-28 Xerox Corporation Mandrel with flared, dish shaped disk and process for using mandrel
CA2152594C (en) 1993-01-19 1998-12-01 David W. Mayer Clad composite stent
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5340614A (en) 1993-02-11 1994-08-23 Minnesota Mining And Manufacturing Company Methods of polymer impregnation
US6228879B1 (en) 1997-10-16 2001-05-08 The Children's Medical Center Methods and compositions for inhibition of angiogenesis
ES2113094T3 (es) 1993-03-09 1998-04-16 Epic Therapeutics Inc Las microparticulas macromoleculares y metodos de obtencion.
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
EP0689465A1 (en) 1993-03-18 1996-01-03 Cedars-Sinai Medical Center Drug incorporating and releasing polymeric coating for bioprosthesis
US20020055710A1 (en) 1998-04-30 2002-05-09 Ronald J. Tuch Medical device for delivering a therapeutic agent and method of preparation
US5403347A (en) 1993-05-27 1995-04-04 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
US5350627A (en) 1993-06-11 1994-09-27 Camelot Technologies, Inc. Coated webs
US5380299A (en) 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
DE4336209C2 (de) 1993-09-10 1995-09-21 Michael Dr Simon Verfahren zur Herstellung einer mit antithrombotischen Agenzien beschichteten Gefäßprothese
US5632772A (en) 1993-10-21 1997-05-27 Corvita Corporation Expandable supportive branched endoluminal grafts
US5350361A (en) 1993-11-10 1994-09-27 Medtronic, Inc. Tri-fold balloon for dilatation catheter and related method
US5494620A (en) 1993-11-24 1996-02-27 United States Surgical Corporation Method of manufacturing a monofilament suture
US5626611A (en) 1994-02-10 1997-05-06 United States Surgical Corporation Composite bioabsorbable materials and surgical articles made therefrom
ES2141928T5 (es) 1994-03-02 2009-04-16 Boston Scientific Limited Balones de elastomero de copolimero en bloques para cateter.
US6146356A (en) 1994-03-02 2000-11-14 Scimed Life Systems, Inc. Block copolymer elastomer catheter balloons
US5843120A (en) 1994-03-17 1998-12-01 Medinol Ltd. Flexible-expandable stent
US5733303A (en) 1994-03-17 1998-03-31 Medinol Ltd. Flexible expandable stent
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
CA2192821A1 (en) 1994-06-24 1996-01-04 Wayne R. Gombotz Controlled release polypeptide compositions and methods of treating inflammatory bowel disease
HU225964B1 (en) 1994-07-12 2008-01-28 Berwind Pharma Service Moisture barrier film coating composition, method, and coated form
US5626862A (en) 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
NL9401690A (nl) 1994-10-13 1996-05-01 Industrial Res Bv In een lichaamsvat implanteerbare stent.
JPH10510450A (ja) 1994-12-02 1998-10-13 サイエンス インコーポレイテッド 薬剤分配装置
EP0805678B1 (en) 1995-01-05 2003-10-29 THE BOARD OF REGENTS acting for and on behalf of THE UNIVERSITY OF MICHIGAN Surface-modified nanoparticles and method of making and using same
US5599576A (en) 1995-02-06 1997-02-04 Surface Solutions Laboratories, Inc. Medical apparatus with scratch-resistant coating and method of making same
US6231600B1 (en) 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
US5605696A (en) 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
CA2216943C (en) 1995-04-19 2003-06-17 Schneider (Usa) Inc. Drug release coated stent
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US6120536A (en) 1995-04-19 2000-09-19 Schneider (Usa) Inc. Medical devices with long term non-thrombogenic coatings
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US20020091433A1 (en) 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US5570537A (en) 1995-04-27 1996-11-05 Black; Douglas A. Electronic insecticidal cable
CN1136922C (zh) 1995-05-01 2004-02-04 株式会社三养社 可植入的可生物再吸收的膜及其制备方法
US6602281B1 (en) 1995-06-05 2003-08-05 Avantec Vascular Corporation Radially expansible vessel scaffold having beams and expansion joints
US5714007A (en) 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US5674242A (en) 1995-06-06 1997-10-07 Quanam Medical Corporation Endoprosthetic device with therapeutic compound
CA2178541C (en) 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
US5609629A (en) 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
WO1996041807A1 (en) 1995-06-09 1996-12-27 Novartis Ag Rapamycin derivatives
US6256529B1 (en) 1995-07-26 2001-07-03 Burdette Medical Systems, Inc. Virtual reality 3D visualization for surgical procedures
JP3476604B2 (ja) 1995-08-22 2003-12-10 鐘淵化学工業株式会社 薬剤を付着・コーティングしたステントの製造方法
EP0764675B1 (en) 1995-09-19 1998-05-13 Mitsubishi Gas Chemical Company, Inc. Biodegrable water-soluble polymer
US5607442A (en) 1995-11-13 1997-03-04 Isostent, Inc. Stent with improved radiopacity and appearance characteristics
CA2192520A1 (en) 1996-03-05 1997-09-05 Ian M. Penn Expandable stent and method for delivery of same
US6461644B1 (en) 1996-03-25 2002-10-08 Richard R. Jackson Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods
NZ331269A (en) 1996-04-10 2000-01-28 Advanced Cardiovascular System Expandable stent, its structural strength varying along its length
US5669932A (en) 1996-05-29 1997-09-23 Isostent, Inc. Means for accurately positioning an expandable stent
KR20000016116A (ko) 1996-05-31 2000-03-25 시게후치 마사토시 방오성 부재 및 방오성 코팅 조성물
US6143037A (en) 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US5876426A (en) 1996-06-13 1999-03-02 Scimed Life Systems, Inc. System and method of providing a blood-free interface for intravascular light delivery
FR2750897B1 (fr) 1996-07-10 1998-09-18 Sames Sa Projecteur triboelectrique, installation de projection de produit de revetement et procede de commande d'un tel projecteur
EP0937082A2 (en) 1996-07-12 1999-08-25 Ariad Pharmaceuticals, Inc. Materials and method for treating or preventing pathogenic fungal infection
JPH1029524A (ja) 1996-07-15 1998-02-03 Toyota Motor Corp 車輪スリップ制御装置
US5871436A (en) 1996-07-19 1999-02-16 Advanced Cardiovascular Systems, Inc. Radiation therapy method and device
DE69722720T2 (de) 1996-07-24 2004-05-13 Cordis Corp., Miami Lakes Ballonkatheter und Methode zur Anwendung
US6013855A (en) 1996-08-06 2000-01-11 United States Surgical Grafting of biocompatible hydrophilic polymers onto inorganic and metal surfaces
DE19633901A1 (de) 1996-08-22 1998-02-26 Thomas Prof Dr Med Ischinger Gefäßstütze in Form einer Schlauchabschnitts-artigen Stützstruktur
US6884377B1 (en) 1996-08-27 2005-04-26 Trexel, Inc. Method and apparatus for microcellular polymer extrusion
US5807404A (en) 1996-09-19 1998-09-15 Medinol Ltd. Stent with variable features to optimize support and method of making such stent
US6193963B1 (en) 1996-10-17 2001-02-27 The Regents Of The University Of California Method of treating tumor-bearing patients with human plasma hyaluronidase
US6387121B1 (en) 1996-10-21 2002-05-14 Inflow Dynamics Inc. Vascular and endoluminal stents with improved coatings
US6530951B1 (en) 1996-10-24 2003-03-11 Cook Incorporated Silver implantable medical device
GB9623634D0 (en) 1996-11-13 1997-01-08 Bpsi Holdings Inc Method and apparatus for the coating of substrates for pharmaceutical use
US6251980B1 (en) 1996-12-06 2001-06-26 Amcol International Corporation Nanocomposites formed by onium ion-intercalated clay and rigid anhydride-cured epoxy resins
US5871437A (en) 1996-12-10 1999-02-16 Inflow Dynamics, Inc. Radioactive stent for treating blood vessels to prevent restenosis
ZA9711732B (en) 1996-12-31 1998-12-28 Quadrant Holdings Cambridge Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery
FR2758253B1 (fr) 1997-01-10 1999-04-02 Nycomed Lab Sa Dispositif implantable pour le traitement d'un conduit corporel
US6884823B1 (en) 1997-01-16 2005-04-26 Trexel, Inc. Injection molding of polymeric material
DE29702671U1 (de) 1997-02-17 1997-04-10 Jomed Implantate GmbH, 72414 Rangendingen Stent
ATE278397T1 (de) 1997-03-31 2004-10-15 Boston Scient Ltd Verwendung von cytoskelettinhibitoren zur vorbeugung der restenose
US6273913B1 (en) 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
IT1292295B1 (it) 1997-04-29 1999-01-29 Sorin Biomedica Cardio Spa Stent per angioplastica
FR2762777B1 (fr) 1997-05-05 1999-10-22 Patrick Sabaria Extenseurs vasculaires et coronaires, habituellement designes sous le nom de "stent"
GB9800936D0 (en) 1997-05-10 1998-03-11 Univ Nottingham Biofunctional polymers
DE19720115C2 (de) 1997-05-14 1999-05-20 Jomed Implantate Gmbh Stent-Graft
CA2308396A1 (en) 1997-05-14 1998-11-19 Novo Rps Ulc Expandable stent and method for production of same
DE29708689U1 (de) 1997-05-15 1997-07-17 Jomed Implantate GmbH, 72414 Rangendingen Koronarer Stent
US5913895A (en) 1997-06-02 1999-06-22 Isostent, Inc. Intravascular stent with enhanced rigidity strut members
US6416779B1 (en) 1997-06-11 2002-07-09 Umd, Inc. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
US6245103B1 (en) 1997-08-01 2001-06-12 Schneider (Usa) Inc Bioabsorbable self-expanding stent
US6077880A (en) 1997-08-08 2000-06-20 Cordis Corporation Highly radiopaque polyolefins and method for making the same
WO1999008729A1 (en) 1997-08-13 1999-02-25 Boston Scientific Limited Loading and release of water-insoluble drugs
JP4352613B2 (ja) 1997-08-28 2009-10-28 日産化学工業株式会社 血管新生促進剤及び血管新生作用増強剤
DE29716476U1 (de) 1997-09-13 1997-12-18 Convent, Gerd, 47829 Krefeld Stent zur Stenosebehandlung
DE29716467U1 (de) 1997-09-15 1998-02-26 Rittal-Werk Rudolf Loh Gmbh & Co Kg, 35745 Herborn Gehäuseaufbau für elektrische oder elektronische Einbauten
US7378105B2 (en) 1997-09-26 2008-05-27 Abbott Laboratories Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens
US8257725B2 (en) 1997-09-26 2012-09-04 Abbott Laboratories Delivery of highly lipophilic agents via medical devices
TW557297B (en) 1997-09-26 2003-10-11 Abbott Lab Rapamycin analogs having immunomodulatory activity, and pharmaceutical compositions containing same
US6042606A (en) 1997-09-29 2000-03-28 Cook Incorporated Radially expandable non-axially contracting surgical stent
US6071308A (en) 1997-10-01 2000-06-06 Boston Scientific Corporation Flexible metal wire stent
US6127000A (en) 1997-10-10 2000-10-03 North Carolina State University Method and compositions for protecting civil infrastructure
ATE452598T1 (de) 1997-11-07 2010-01-15 Salviac Ltd Embolieschutzvorrichtung
DE59808721D1 (de) 1997-11-24 2003-07-17 Efmt Entwicklungs Und Forschun Verfahren zur immobilisierung von mediatormolekülen auf anorganischen und metallischen implantatmaterialien
US5957975A (en) 1997-12-15 1999-09-28 The Cleveland Clinic Foundation Stent having a programmed pattern of in vivo degradation
CA2314963A1 (en) 1998-01-06 1999-07-15 Bioamide, Inc. Bioabsorbable fibers and reinforced composites produced therefrom
US6129755A (en) 1998-01-09 2000-10-10 Nitinol Development Corporation Intravascular stent having an improved strut configuration
DE69942515D1 (de) 1998-03-04 2010-07-29 Boston Scient Ltd Stent mit verbesserter Zellkonfiguration
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
SE9801288D0 (sv) 1998-04-14 1998-04-14 Astra Ab Vaccine delivery system and metod of production
US8029561B1 (en) 2000-05-12 2011-10-04 Cordis Corporation Drug combination useful for prevention of restenosis
GB9808052D0 (en) 1998-04-17 1998-06-17 Secr Defence Implants for administering substances and methods of producing implants
US6206914B1 (en) 1998-04-30 2001-03-27 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US6190699B1 (en) 1998-05-08 2001-02-20 Nzl Corporation Method of incorporating proteins or peptides into a matrix and administration thereof through mucosa
DE19822157B4 (de) 1998-05-16 2013-01-10 Abbott Laboratories Vascular Enterprises Ltd. Radial aufweitbarer Stent zur Implantierung in ein Körpergefäß
FR2780057B1 (fr) 1998-06-18 2002-09-13 Sanofi Sa Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant
ATE246522T1 (de) 1998-06-19 2003-08-15 Oxibio Inc Implantierbare medizinische vorrichtung mit antiinfektiösen und kontrazeptiven eigenschaften
US6153252A (en) 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
US6541033B1 (en) 1998-06-30 2003-04-01 Amgen Inc. Thermosensitive biodegradable hydrogels for sustained delivery of leptin
US7967855B2 (en) 1998-07-27 2011-06-28 Icon Interventional Systems, Inc. Coated medical device
US8070796B2 (en) 1998-07-27 2011-12-06 Icon Interventional Systems, Inc. Thrombosis inhibiting graft
US7004962B2 (en) 1998-07-27 2006-02-28 Schneider (Usa), Inc. Neuroaneurysm occlusion and delivery device and method of using same
US6461380B1 (en) 1998-07-28 2002-10-08 Advanced Cardiovascular Systems, Inc. Stent configuration
US6248127B1 (en) 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device
US6193744B1 (en) 1998-09-10 2001-02-27 Scimed Life Systems, Inc. Stent configurations
US6342062B1 (en) 1998-09-24 2002-01-29 Scimed Life Systems, Inc. Retrieval devices for vena cava filter
US6363104B1 (en) 1998-10-02 2002-03-26 Ericsson Inc. Method and apparatus for interference cancellation in a rake receiver
US6245104B1 (en) 1999-02-28 2001-06-12 Inflow Dynamics Inc. Method of fabricating a biocompatible stent
US6042597A (en) 1998-10-23 2000-03-28 Scimed Life Systems, Inc. Helical stent design
US6143314A (en) 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
FR2785174A1 (fr) 1998-11-03 2000-05-05 Jacques Seguin Extenseur de conduit corporel, notamment vasculaire
US6355691B1 (en) 1998-11-12 2002-03-12 Tobias M. Goodman Urushiol therapy of transitional cell carcinoma of the bladder
EP1131114B1 (en) 1998-11-20 2004-06-16 The University of Connecticut Apparatus and method for control of tissue/implant interactions
AU1821200A (en) 1998-12-03 2000-06-19 Scimed Life Systems, Inc. Stent having drug crystals thereon
US6372246B1 (en) 1998-12-16 2002-04-16 Ortho-Mcneil Pharmaceutical, Inc. Polyethylene glycol coating for electrostatic dry deposition of pharmaceuticals
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6147135A (en) 1998-12-31 2000-11-14 Ethicon, Inc. Fabrication of biocompatible polymeric composites
US6638727B1 (en) 1999-01-26 2003-10-28 Cytyc Health Corporation Methods for identifying treating or monitoring asymptomatic patients for risk reduction or therapeutic treatment of breast cancer
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
SE9900519D0 (sv) 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6171327B1 (en) 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6620192B1 (en) 1999-03-16 2003-09-16 Advanced Cardiovascular Systems, Inc. Multilayer stent
SE9901002D0 (sv) 1999-03-19 1999-03-19 Electrolux Ab Anordning för rengöring av textilföremål med en förtätad vätskeformig behandlingsgas
US6364903B2 (en) 1999-03-19 2002-04-02 Meadox Medicals, Inc. Polymer coated stent
US6368658B1 (en) 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6923979B2 (en) 1999-04-27 2005-08-02 Microdose Technologies, Inc. Method for depositing particles onto a substrate using an alternating electric field
US8016873B1 (en) 1999-05-03 2011-09-13 Drasler William J Intravascular hinge stent
US6726712B1 (en) 1999-05-14 2004-04-27 Boston Scientific Scimed Prosthesis deployment device with translucent distal end
JP2000316981A (ja) 1999-05-14 2000-11-21 Kawasumi Lab Inc ステント
US6815218B1 (en) 1999-06-09 2004-11-09 Massachusetts Institute Of Technology Methods for manufacturing bioelectronic devices
CN1390126B (zh) 1999-07-06 2012-06-13 恩多研究公司 选择性雌激素受体调节剂在制备用于治疗或降低肥胖症发展危险性的药物中的用途
AU783158B2 (en) 1999-08-24 2005-09-29 Ariad Pharmaceuticals, Inc. 28-epirapalogs
US6146404A (en) 1999-09-03 2000-11-14 Scimed Life Systems, Inc. Removable thrombus filter
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
US6358557B1 (en) 1999-09-10 2002-03-19 Sts Biopolymers, Inc. Graft polymerization of substrate surfaces
US6610013B1 (en) 1999-10-01 2003-08-26 Life Imaging Systems, Inc. 3D ultrasound-guided intraoperative prostate brachytherapy
US6755871B2 (en) 1999-10-15 2004-06-29 R.R. Street & Co. Inc. Cleaning system utilizing an organic cleaning solvent and a pressurized fluid solvent
US6458387B1 (en) 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
US7537785B2 (en) 1999-10-29 2009-05-26 Nitromed, Inc. Composition for treating vascular diseases characterized by nitric oxide insufficiency
US6537310B1 (en) 1999-11-19 2003-03-25 Advanced Bio Prosthetic Surfaces, Ltd. Endoluminal implantable devices and method of making same
US6908624B2 (en) 1999-12-23 2005-06-21 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6572813B1 (en) 2000-01-13 2003-06-03 Advanced Cardiovascular Systems, Inc. Balloon forming process
TWI284048B (en) 2000-01-27 2007-07-21 Zentaris Ag Compressed microparticles for dry injection
EP1132058A1 (en) 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravascular prothesis
EP1145719A3 (en) 2000-03-10 2001-11-14 Pfizer Products Inc. Use a ferrous salt for inhibiting oxidative degradation of pharmaceutical formulations
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
CN2423899Y (zh) 2000-05-08 2001-03-21 微创医疗器械(上海)有限公司 冠状动脉支架
AU6145501A (en) 2000-05-12 2001-11-26 Advanced Bio Prosthetic Surfac Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same
MXPA02011427A (es) 2000-05-16 2004-09-10 Johnson & Johnson Procedimiento para revestir dispositivos medicos utilizando dioxido de carbono supercritico.
US7217770B2 (en) 2000-05-17 2007-05-15 Samyang Corporation Stable polymeric micelle-type drug composition and method for the preparation thereof
US20020144757A1 (en) 2000-07-07 2002-10-10 Craig Charles Horace Stainless steel alloy with improved radiopaque characteristics
US20030077200A1 (en) 2000-07-07 2003-04-24 Craig Charles H. Enhanced radiopaque alloy stent
EP1317304B1 (en) 2000-09-01 2011-04-27 Palmaya Pty Ltd. Slow release pharmaceutical preparation and method of administering same
US7332242B2 (en) 2000-09-01 2008-02-19 Itochu Corporation Lithium-based battery having extensible, ion-impermeable polymer covering on the battery container
US6362718B1 (en) 2000-09-06 2002-03-26 Stephen L. Patrick Motionless electromagnetic generator
US6506213B1 (en) 2000-09-08 2003-01-14 Ferro Corporation Manufacturing orthopedic parts using supercritical fluid processing techniques
US6521258B1 (en) 2000-09-08 2003-02-18 Ferro Corporation Polymer matrices prepared by supercritical fluid processing techniques
US6953560B1 (en) 2000-09-28 2005-10-11 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
AU1129902A (en) 2000-09-29 2002-04-08 Cordis Corp Coated medical devices
US20060222756A1 (en) 2000-09-29 2006-10-05 Cordis Corporation Medical devices, drug coatings and methods of maintaining the drug coatings thereon
US20020111590A1 (en) 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
JP2004537495A (ja) 2000-11-03 2004-12-16 コントロール・デリバリー・システムズ 関節疾患を治療するための改善された装置及び方法
US20040018228A1 (en) 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
US20050084514A1 (en) 2000-11-06 2005-04-21 Afmedica, Inc. Combination drug therapy for reducing scar tissue formation
WO2002040702A2 (en) 2000-11-09 2002-05-23 Vanderbilt University Methods for the treatment of cancer and other diseases and methods of developing the same
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
JP4868565B2 (ja) 2000-11-30 2012-02-01 株式会社 京都医療設計 血管用ステント
US6913617B1 (en) 2000-12-27 2005-07-05 Advanced Cardiovascular Systems, Inc. Method for creating a textured surface on an implantable medical device
GB0100760D0 (en) 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
GB0100761D0 (en) 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
TWI246524B (en) 2001-01-19 2006-01-01 Shearwater Corp Multi-arm block copolymers as drug delivery vehicles
US6660176B2 (en) 2001-01-24 2003-12-09 Virginia Commonwealth University Molecular imprinting of small particles, and production of small particles from solid state reactants
IL151150A0 (en) 2001-01-31 2003-04-10 Roehm Gmbh Multiparticulate drug form comprising at least two differently coated pellet forms
US20040220660A1 (en) 2001-02-05 2004-11-04 Shanley John F. Bioresorbable stent with beneficial agent reservoirs
DE10106810A1 (de) 2001-02-14 2002-09-05 Siemens Ag Netzunabhängige Stromversorgungseinheit
US6905555B2 (en) 2001-02-15 2005-06-14 Micell Technologies, Inc. Methods for transferring supercritical fluids in microelectronic and other industrial processes
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
US6811549B2 (en) 2001-02-16 2004-11-02 William H. Fleming Administration of therapeutic or diagnostic agents using interlabial pad
US6949251B2 (en) 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
US7771468B2 (en) 2001-03-16 2010-08-10 Angiotech Biocoatings Corp. Medicated stent having multi-layer polymer coating
JP2004526499A (ja) 2001-03-16 2004-09-02 エスティーエス バイオポリマーズ,インコーポレイティド 複数層ポリマーコーティングを有する薬物添加ステント
WO2002085188A2 (en) 2001-04-24 2002-10-31 Kaplan Edward J Deflectable implantation device and method for use
US20040022853A1 (en) 2001-04-26 2004-02-05 Control Delivery Systems, Inc. Polymer-based, sustained release drug delivery system
US7247338B2 (en) 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
US6973718B2 (en) 2001-05-30 2005-12-13 Microchips, Inc. Methods for conformal coating and sealing microchip reservoir devices
US7201940B1 (en) 2001-06-12 2007-04-10 Advanced Cardiovascular Systems, Inc. Method and apparatus for thermal spray processing of medical devices
US20030044514A1 (en) 2001-06-13 2003-03-06 Richard Robert E. Using supercritical fluids to infuse therapeutic on a medical device
US7485113B2 (en) 2001-06-22 2009-02-03 Johns Hopkins University Method for drug delivery through the vitreous humor
US7501157B2 (en) 2001-06-26 2009-03-10 Accelr8 Technology Corporation Hydroxyl functional surface coating
US6585755B2 (en) 2001-06-29 2003-07-01 Advanced Cardiovascular Polymeric stent suitable for imaging by MRI and fluoroscopy
US6967234B2 (en) 2002-12-18 2005-11-22 Ethicon, Inc. Alkyd-lactone copolymers for medical applications
US7015875B2 (en) 2001-06-29 2006-03-21 Novus Partners Llc Dynamic device for billboard advertising
US6743505B2 (en) 2001-07-27 2004-06-01 Ethicon, Inc. Bioabsorbable multifilament yarn and methods of manufacture
US6723913B1 (en) 2001-08-23 2004-04-20 Anthony T. Barbetta Fan cooling of active speakers
US6669980B2 (en) 2001-09-18 2003-12-30 Scimed Life Systems, Inc. Method for spray-coating medical devices
WO2003034944A1 (de) 2001-10-15 2003-05-01 Hemoteq Gmbh Beschichtung von stents zur verhinderung von restenose
US20030088307A1 (en) 2001-11-05 2003-05-08 Shulze John E. Potent coatings for stents
US6939376B2 (en) 2001-11-05 2005-09-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis
CA2466336A1 (en) 2001-11-09 2003-05-15 Ebrahim Versi Anti-muscarinic agent and estrogen-agonist for treating unstable or overactive bladder
US6517889B1 (en) 2001-11-26 2003-02-11 Swaminathan Jayaraman Process for coating a surface of a stent
US7488313B2 (en) 2001-11-29 2009-02-10 Boston Scientific Scimed, Inc. Mechanical apparatus and method for dilating and delivering a therapeutic agent to a site of treatment
US6868123B2 (en) 2001-12-07 2005-03-15 Motorola, Inc. Programmable motion estimation module with vector array unit
TW497494U (en) 2001-12-28 2002-08-01 Metal Ind Redearch & Amp Dev C Fluid driven stirring device for compressing gas cleaning system
DE10200388A1 (de) 2002-01-08 2003-07-24 Translumina Gmbh Beschichtungssystem
KR20040076278A (ko) 2002-01-10 2004-08-31 노파르티스 아게 라파마이신 및 그의 유도체를 포함하는, 혈관 질환의 예방및 치료를 위한 약물 전달 시스템
US20030135256A1 (en) 2002-01-14 2003-07-17 Gallagher Brendan P. Stent delivery system
HUP0402591A2 (hu) 2002-02-15 2005-09-28 Cv Therapeutics, Inc. Polimer bevonat orvosi eszközök számára
US20060093771A1 (en) 2002-02-15 2006-05-04 Frantisek Rypacek Polymer coating for medical devices
PL371466A1 (en) 2002-02-28 2005-06-13 Novartis Ag N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine coated stents
WO2003074992A2 (en) 2002-03-01 2003-09-12 Mds Proteomics Inc. Phosphorylated proteins and uses related thereto
GB0205868D0 (en) 2002-03-13 2002-04-24 Univ Nottingham Polymer composite with internally distributed deposition matter
US7919075B1 (en) 2002-03-20 2011-04-05 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices
US6743463B2 (en) 2002-03-28 2004-06-01 Scimed Life Systems, Inc. Method for spray-coating a medical device having a tubular wall such as a stent
US7470281B2 (en) 2002-04-26 2008-12-30 Medtronic Vascular, Inc. Coated stent with crimpable coating
US7270675B2 (en) 2002-05-10 2007-09-18 Cordis Corporation Method of forming a tubular membrane on a structural frame
US6669785B2 (en) 2002-05-15 2003-12-30 Micell Technologies, Inc. Methods and compositions for etch cleaning microelectronic substrates in carbon dioxide
ATE460994T1 (de) 2002-05-28 2010-04-15 Battelle Memorial Institute Elektrostatische abscheidung von durch schnelle entspannung überkritischer lösungen (ress) erhaltene partikel
US6756084B2 (en) 2002-05-28 2004-06-29 Battelle Memorial Institute Electrostatic deposition of particles generated from rapid expansion of supercritical fluid solutions
US6749902B2 (en) 2002-05-28 2004-06-15 Battelle Memorial Institute Methods for producing films using supercritical fluid
US6780475B2 (en) 2002-05-28 2004-08-24 Battelle Memorial Institute Electrostatic deposition of particles generated from rapid expansion of supercritical fluid solutions
US7229837B2 (en) 2002-05-30 2007-06-12 Uchicago Argonne, Llc Enhanced photophysics of conjugated polymers
TW200403065A (en) 2002-05-30 2004-03-01 Akzo Nobel Nv New etonogestrel esters
CN100369593C (zh) 2002-06-05 2008-02-20 佛罗里达大学研究基金会有限公司 眼科给药体系
CA2489362A1 (en) 2002-06-13 2003-12-24 Kappler, Inc. Microporous membrane with adsorbent multi-functional filler
US6794902B2 (en) 2002-06-14 2004-09-21 Sun Microsystems, Inc. Virtual ground circuit
US7033602B1 (en) 2002-06-21 2006-04-25 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of coating implantable medical devices
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US6839913B2 (en) 2002-06-25 2005-01-11 Noble Ideas, Inc. Adjustable garment waistband and method of manufacture
WO2004002367A1 (fr) 2002-06-27 2004-01-08 Microport Medical (Shanghai) Co., Ltd. Stent eluant des medicaments
CN100471469C (zh) 2002-06-27 2009-03-25 微创医疗器械(上海)有限公司 一种具有多层涂层的药物洗脱支架
US20040013792A1 (en) 2002-07-19 2004-01-22 Samuel Epstein Stent coating holders
US7491233B1 (en) 2002-07-19 2009-02-17 Advanced Cardiovascular Systems Inc. Purified polymers for coatings of implantable medical devices
JP2004058431A (ja) 2002-07-29 2004-02-26 Nitto Denko Corp 粘着テープ又はシート
GB2391439B (en) 2002-07-30 2006-06-21 Wolfson Ltd Bass compressor
US20050019747A1 (en) 2002-08-07 2005-01-27 Anderson Daniel G. Nanoliter-scale synthesis of arrayed biomaterials and screening thereof
US7029495B2 (en) 2002-08-28 2006-04-18 Scimed Life Systems, Inc. Medical devices and methods of making the same
US7060051B2 (en) 2002-09-24 2006-06-13 Scimed Life Systems, Inc. Multi-balloon catheter with hydrogel coating
JP2006500996A (ja) 2002-09-26 2006-01-12 エンドバスキュラー デバイセス インコーポレイテッド 溶出性生体適合性移植可能医療器具を介してマイトマイシンを送達するための装置および方法
US6702850B1 (en) 2002-09-30 2004-03-09 Mediplex Corporation Korea Multi-coated drug-eluting stent for antithrombosis and antirestenosis
US6770729B2 (en) 2002-09-30 2004-08-03 Medtronic Minimed, Inc. Polymer compositions containing bioactive agents and methods for their use
US20050010275A1 (en) 2002-10-11 2005-01-13 Sahatjian Ronald A. Implantable medical devices
US6800663B2 (en) 2002-10-18 2004-10-05 Alkermes Controlled Therapeutics Inc. Ii, Crosslinked hydrogel copolymers
KR100511030B1 (ko) 2002-10-21 2005-08-31 한국과학기술연구원 혈액적합성 의료용 금속 재료 및 이의 제조 방법
WO2004043383A2 (en) 2002-11-07 2004-05-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services A new target for angiogenesis and anti-angiogenesis therapy
US20050070989A1 (en) 2002-11-13 2005-03-31 Whye-Kei Lye Medical devices having porous layers and methods for making the same
US20060121080A1 (en) 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
US20040098106A1 (en) 2002-11-14 2004-05-20 Williams Michael S. Intraluminal prostheses and carbon dioxide-assisted methods of impregnating same with pharmacological agents
CA2503388C (en) 2002-11-15 2012-05-15 Synecor, Llc Improved endoprostheses and methods of manufacture
CA2506319C (en) 2002-11-18 2012-08-28 Polymerix Corporation Stents comprising biodegradable polymers associated with therapeutic agents
JP4371653B2 (ja) 2002-11-25 2009-11-25 テルモ株式会社 体内埋込医療器具
US6790483B2 (en) 2002-12-06 2004-09-14 Eastman Kodak Company Method for producing patterned deposition from compressed fluid
US7094256B1 (en) 2002-12-16 2006-08-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical device containing polycationic peptides
EP1578193A4 (en) 2002-12-23 2011-06-15 Vical Inc FREEZING PROCESS FOR NUCLEIC ACID / BLOCK COPOLYMER / CATION SIDE COMPLEXES
US7152452B2 (en) 2002-12-26 2006-12-26 Advanced Cardiovascular Systems, Inc. Assembly for crimping an intraluminal device and method of use
US20040143317A1 (en) 2003-01-17 2004-07-22 Stinson Jonathan S. Medical devices
US7309349B2 (en) 2003-01-23 2007-12-18 Cordis Corporation Friction reducing lubricant for stent loading and stent delivery systems
JP2004225126A (ja) 2003-01-24 2004-08-12 Pioneer Electronic Corp 成膜用マスクとその製造方法
US20050079199A1 (en) 2003-02-18 2005-04-14 Medtronic, Inc. Porous coatings for drug release from medical devices
US20080051866A1 (en) 2003-02-26 2008-02-28 Chao Chin Chen Drug delivery devices and methods
EP1603485A4 (en) 2003-02-26 2011-03-30 Medivas Llc BIOACTIVE STENTS AND METHOD OF USE THEREOF
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US20040193262A1 (en) 2003-03-29 2004-09-30 Shadduck John H. Implants for treating ocular hypertension, methods of use and methods of fabrication
US7527632B2 (en) 2003-03-31 2009-05-05 Cordis Corporation Modified delivery device for coated medical devices
US7326734B2 (en) 2003-04-01 2008-02-05 The Regents Of The University Of California Treatment of bladder and urinary tract cancers
US20050216075A1 (en) 2003-04-08 2005-09-29 Xingwu Wang Materials and devices of enhanced electromagnetic transparency
US20060102871A1 (en) 2003-04-08 2006-05-18 Xingwu Wang Novel composition
WO2004091571A2 (en) 2003-04-08 2004-10-28 New Jersey Institute Of Technology (Njit) Polymer coating/encapsulation of nanoparticles using a supercritical antisolvent process
US20050208102A1 (en) 2003-04-09 2005-09-22 Schultz Clyde L Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
US20050038498A1 (en) 2003-04-17 2005-02-17 Nanosys, Inc. Medical device applications of nanostructured surfaces
US8246974B2 (en) 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
GB0310300D0 (en) 2003-05-06 2003-06-11 Univ Belfast Nanocomposite drug delivery composition
US7279174B2 (en) 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
US7553827B2 (en) 2003-08-13 2009-06-30 Depuy Spine, Inc. Transdiscal administration of cycline compounds
US7429378B2 (en) 2003-05-13 2008-09-30 Depuy Spine, Inc. Transdiscal administration of high affinity anti-MMP inhibitors
CA2519742A1 (en) 2003-05-16 2004-11-25 Blue Membranes Gmbh Medical implants comprising biocompatible coatings
US7524527B2 (en) 2003-05-19 2009-04-28 Boston Scientific Scimed, Inc. Electrostatic coating of a device
US20040236416A1 (en) 2003-05-20 2004-11-25 Robert Falotico Increased biocompatibility of implantable medical devices
US7662864B2 (en) 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
WO2004108274A1 (ja) 2003-06-06 2004-12-16 Mitsubishi Chemical Corporation 吸水性物品およびその製造方法
WO2004113429A2 (en) 2003-06-23 2004-12-29 The University Of Chicago Polyolefin nanocomposites
US8399013B2 (en) 2003-06-26 2013-03-19 Poly-Med, Inc. Partially absorbable fiber-reinforced composites for controlled drug delivery
US7318945B2 (en) 2003-07-09 2008-01-15 Medtronic Vascular, Inc. Laminated drug-polymer coated stent having dipped layers
US8025637B2 (en) 2003-07-18 2011-09-27 Boston Scientific Scimed, Inc. Medical balloons and processes for preparing same
US7128277B2 (en) 2003-07-29 2006-10-31 Illinois Tool Works Inc. Powder bell with secondary charging electrode
US7169404B2 (en) 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same
US7056591B1 (en) 2003-07-30 2006-06-06 Advanced Cardiovascular Systems, Inc. Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same
US20050033417A1 (en) 2003-07-31 2005-02-10 John Borges Coating for controlled release of a therapeutic agent
KR20060052722A (ko) 2003-08-05 2006-05-19 가부시키가이샤 가네카 생체유치용 스텐트
US7318944B2 (en) 2003-08-07 2008-01-15 Medtronic Vascular, Inc. Extrusion process for coating stents
EP1575565B1 (en) 2003-08-08 2010-01-06 Biovail Laboratories International Srl Modified-release tablet of bupropion hydrochloride
CA2535345A1 (en) 2003-08-13 2005-03-03 Medtronic, Inc. Active agent delivery systems including a miscible polymer blend, medical devices, and methods
US7204560B2 (en) 2003-08-15 2007-04-17 Sandvik Intellectual Property Ab Rotary cutting bit with material-deflecting ledge
JP4732346B2 (ja) 2003-08-19 2011-07-27 バイエル・マテリアルサイエンス・アクチェンゲゼルシャフト 医療機器用の高分子薬剤溶出システム
CN101094622A (zh) 2003-09-18 2007-12-26 先进生物假体表面有限公司 具有MEMs功能的医疗装置及其制造方法
US7785653B2 (en) 2003-09-22 2010-08-31 Innovational Holdings Llc Method and apparatus for loading a beneficial agent into an expandable medical device
US8801692B2 (en) 2003-09-24 2014-08-12 Medtronic Vascular, Inc. Gradient coated stent and method of fabrication
US20050070990A1 (en) 2003-09-26 2005-03-31 Stinson Jonathan S. Medical devices and methods of making same
US7744645B2 (en) 2003-09-29 2010-06-29 Medtronic Vascular, Inc. Laminated drug-polymer coated stent with dipped and cured layers
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US7618647B2 (en) 2003-10-03 2009-11-17 Boston Scientific Scimed, Inc. Using bucky paper as a therapeutic aid in medical applications
US6984411B2 (en) 2003-10-14 2006-01-10 Boston Scientific Scimed, Inc. Method for roll coating multiple stents
US7329383B2 (en) 2003-10-22 2008-02-12 Boston Scientific Scimed, Inc. Alloy compositions and devices including the compositions
JP2007509220A (ja) 2003-10-23 2007-04-12 ユニバーシテイ・オブ・ノツテインガム 活性ポリマー押出物の調製
US7220755B2 (en) * 2003-11-12 2007-05-22 Biosensors International Group, Ltd. 42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
ES2293368T3 (es) 2003-12-16 2008-03-16 Cytec Surface Specialties, S.A. Proceso para aplicar un recubrimiento a una banda metalica enrollada.
US20050131513A1 (en) 2003-12-16 2005-06-16 Cook Incorporated Stent catheter with a permanently affixed conductor
JP4796506B2 (ja) 2003-12-24 2011-10-19 ノバルティス アーゲー 医薬組成物
US20050147734A1 (en) 2004-01-07 2005-07-07 Jan Seppala Method and system for coating tubular medical devices
US20050268573A1 (en) 2004-01-20 2005-12-08 Avantec Vascular Corporation Package of sensitive articles
US7306677B2 (en) 2004-01-30 2007-12-11 Boston Scientific Corporation Clamping fixture for coating stents, system using the fixture, and method of using the fixture
GB2411078B (en) 2004-02-10 2009-02-04 Samsung Electronics Co Ltd Mobile communications
US7241344B2 (en) 2004-02-10 2007-07-10 Boston Scientific Scimed, Inc. Apparatus and method for electrostatic spray coating of medical devices
US8551512B2 (en) 2004-03-22 2013-10-08 Advanced Cardiovascular Systems, Inc. Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
WO2005097223A1 (en) 2004-03-26 2005-10-20 Surmodics, Inc. Composition and method for preparing biocompatible surfaces
US7335264B2 (en) 2004-04-22 2008-02-26 Boston Scientific Scimed, Inc. Differentially coated medical devices, system for differentially coating medical devices, and coating method
US7820732B2 (en) 2004-04-30 2010-10-26 Advanced Cardiovascular Systems, Inc. Methods for modulating thermal and mechanical properties of coatings on implantable devices
US20050288481A1 (en) 2004-04-30 2005-12-29 Desnoyer Jessica R Design of poly(ester amides) for the control of agent-release from polymeric compositions
JP5042820B2 (ja) 2004-05-14 2012-10-03 ベクトン・ディキンソン・アンド・カンパニー 生物活性表面を有する物品およびそれらの無溶媒調製法
WO2005117942A2 (en) 2004-05-14 2005-12-15 The Regents Of The University Of Michigan Methods for encapsulation of biomacromolecules in polymers
US7758892B1 (en) 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US7682656B2 (en) 2004-06-14 2010-03-23 Agruim Inc. Process and apparatus for producing a coated product
US7976557B2 (en) 2004-06-23 2011-07-12 Boston Scientific Scimed, Inc. Cutting balloon and process
CA2511212A1 (en) 2004-07-02 2006-01-02 Henkel Kommanditgesellschaft Auf Aktien Surface conditioner for powder coating systems
EP1773375A1 (en) 2004-07-14 2007-04-18 University of Utah Research Foundation Netrin-related compositions and uses
US20060020325A1 (en) 2004-07-26 2006-01-26 Robert Burgermeister Material for high strength, controlled recoil stent
US8597716B2 (en) * 2009-06-23 2013-12-03 Abbott Cardiovascular Systems Inc. Methods to increase fracture resistance of a drug-eluting medical device
US8541078B2 (en) 2004-08-06 2013-09-24 Societe Bic Fuel supplies for fuel cells
US7425368B2 (en) * 2004-08-20 2008-09-16 Massachusetts Institute Of Technology Filler-enhanced polymeric fibers with improved mechanical properties and method for making
US8119153B2 (en) 2004-08-26 2012-02-21 Boston Scientific Scimed, Inc. Stents with drug eluting coatings
EP1787676A4 (en) 2004-09-08 2012-06-20 Kaneka Corp VASCULAR ENDOPROTHESIS PLACING IN THE BODY
JP2008514706A (ja) 2004-09-29 2008-05-08 コーディス・コーポレイション 安定非晶質ラパマイシン様化合物の薬学的投与形態
US8313763B2 (en) 2004-10-04 2012-11-20 Tolmar Therapeutics, Inc. Sustained delivery formulations of rapamycin compounds
US20060093643A1 (en) 2004-11-04 2006-05-04 Stenzel Eric B Medical device for delivering therapeutic agents over different time periods
US7455658B2 (en) 2004-11-10 2008-11-25 Samw Hong Jen Wang Fluid dispensing or feeding device
US7455688B2 (en) 2004-11-12 2008-11-25 Con Interventional Systems, Inc. Ostial stent
EP1819373A2 (en) 2004-12-07 2007-08-22 SurModics, Inc. Coatings with crystallized active agent(s)
US20070059350A1 (en) 2004-12-13 2007-03-15 Kennedy John P Agents for controlling biological fluids and methods of use thereof
WO2006063430A1 (en) 2004-12-16 2006-06-22 Miv Therapeutics Inc. Multi-layer drug delivery device and method of manufacturing same
US7632307B2 (en) 2004-12-16 2009-12-15 Advanced Cardiovascular Systems, Inc. Abluminal, multilayer coating constructs for drug-delivery stents
US8292944B2 (en) 2004-12-17 2012-10-23 Reva Medical, Inc. Slide-and-lock stent
US20060198868A1 (en) 2005-01-05 2006-09-07 Dewitt David M Biodegradable coating compositions comprising blends
US7727273B2 (en) 2005-01-13 2010-06-01 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
US7772352B2 (en) 2005-01-28 2010-08-10 Bezwada Biomedical Llc Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices
WO2006110197A2 (en) 2005-03-03 2006-10-19 Icon Medical Corp. Polymer biodegradable medical device
US7837726B2 (en) 2005-03-14 2010-11-23 Abbott Laboratories Visible endoprosthesis
KR20070116821A (ko) 2005-03-14 2007-12-11 쓰리엠 이노베이티브 프로퍼티즈 컴파니 의약 제제용 생체적합성 중합체 화합물
WO2006101972A2 (en) 2005-03-17 2006-09-28 Elan Pharma International Limited Injectable compositions of nanoparticulate immunosuppressive compounds
JP5271697B2 (ja) 2005-03-23 2013-08-21 アボット ラボラトリーズ 医療装置を介する高親油性薬剤の送達
US8628565B2 (en) 2005-04-13 2014-01-14 Abbott Cardiovascular Systems Inc. Intravascular stent
US20110118827A1 (en) * 2005-06-06 2011-05-19 Dr. Tim Wu Biodegradable stent formed with polymer-bioceramic nanoparticle composite and method of making the same
US20070009564A1 (en) 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
EP1909973B1 (en) 2005-07-15 2018-08-22 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
US8377462B2 (en) 2005-07-29 2013-02-19 Advanced Cardiovascular Systems, Inc. PEA-TEMPO/PEA-BZ coatings for controlled delivery of drug from implantable medical devices
US20070026042A1 (en) 2005-07-29 2007-02-01 Narayanan Pallasssana V System for treating aneurysmal disease
EP1912614A4 (en) 2005-08-03 2009-08-05 Univ Western Ontario DIRECT COATING OF SOLID DOSAGE FORMS WITH POWDERFILLED SUBSTANCES
US8214504B2 (en) 2005-08-05 2012-07-03 Telecom Italia S.P.A. Method of establishing a connection on a communication network
WO2007017707A1 (en) 2005-08-11 2007-02-15 Hilary Nwokeabia The slanting toothbrush
WO2007022055A1 (en) 2005-08-12 2007-02-22 Massicotte J Mathieu Method and device for extracting objects from the body
US20070043434A1 (en) * 2005-08-18 2007-02-22 David Meerkin Biodegradable endovascular stent using stereocomplexation of polymers
EP1764116A1 (en) 2005-09-16 2007-03-21 Debiotech S.A. Porous coating process using colloidal particles
US7935379B2 (en) 2005-11-14 2011-05-03 Boston Scientific Scimed, Inc. Coated and imprinted medical devices and methods of making the same
US20070196423A1 (en) 2005-11-21 2007-08-23 Med Institute, Inc. Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent
JP2009518479A (ja) 2005-12-09 2009-05-07 ディーエスエム アイピー アセッツ ビー.ブイ. 高分子電解質を含む親水性コーティング
US20070148251A1 (en) 2005-12-22 2007-06-28 Hossainy Syed F A Nanoparticle releasing medical devices
US7842312B2 (en) 2005-12-29 2010-11-30 Cordis Corporation Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
US8834912B2 (en) 2005-12-30 2014-09-16 Boston Scientific Scimed, Inc. Medical devices having multiple charged layers
US7919108B2 (en) 2006-03-10 2011-04-05 Cook Incorporated Taxane coatings for implantable medical devices
US20080286325A1 (en) 2006-01-05 2008-11-20 Med Institute, Inc. Cyclodextrin elution media for medical device coatings comprising a taxane therapeutic agent
US8142509B2 (en) 2006-01-23 2012-03-27 Smith & Nephew, Inc. Patellar components
JP2009525768A (ja) 2006-01-27 2009-07-16 エム イー ディ インスチィチュート インク 薬物の制御放出用ナノコンポジットコーティングを伴う器具
WO2007089259A1 (en) 2006-02-02 2007-08-09 The Johns Hopkins University Therapeutic electrospun fiber compositions
JP4297221B2 (ja) 2006-02-15 2009-07-15 株式会社ホソカワ粉体技術研究所 薬剤溶出型ステントの製造方法
WO2007096832A1 (en) 2006-02-23 2007-08-30 Agamatrix, Inc Used test strip storage container
US20070200268A1 (en) 2006-02-24 2007-08-30 Vipul Dave Implantable device prepared from solution processing
US20070203569A1 (en) 2006-02-24 2007-08-30 Robert Burgermeister Implantable device formed from polymer blends having modified molecular structures
US8500772B2 (en) 2006-03-20 2013-08-06 Cook Medical Technologies Llc Distal protection device
US20070225795A1 (en) * 2006-03-24 2007-09-27 Juan Granada Composite vascular prosthesis
US7955383B2 (en) 2006-04-25 2011-06-07 Medtronics Vascular, Inc. Laminated implantable medical device having a metallic coating
US8852625B2 (en) 2006-04-26 2014-10-07 Micell Technologies, Inc. Coatings containing multiple drugs
US20070254012A1 (en) * 2006-04-28 2007-11-01 Ludwig Florian N Controlled degradation and drug release in stents
US7691400B2 (en) 2006-05-05 2010-04-06 Medtronic Vascular, Inc. Medical device having coating with zeolite drug reservoirs
US20080279909A1 (en) 2006-05-12 2008-11-13 Cleek Robert L Immobilized Biologically Active Entities Having A High Degree of Biological Activity Following Sterilization
US7959940B2 (en) 2006-05-30 2011-06-14 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical devices
US20070281117A1 (en) 2006-06-02 2007-12-06 Xtent, Inc. Use of plasma in formation of biodegradable stent coating
US20080124372A1 (en) 2006-06-06 2008-05-29 Hossainy Syed F A Morphology profiles for control of agent release rates from polymer matrices
BRPI0603437A2 (pt) 2006-06-06 2010-07-06 Luiz Gonzaga Granja Jr prótese para anastomose tipo stent extraluminal
US8535372B1 (en) 2006-06-16 2013-09-17 Abbott Cardiovascular Systems Inc. Bioabsorbable stent with prohealing layer
WO2008008291A2 (en) 2006-07-13 2008-01-17 Icon Medical Corp. Stent
US7820812B2 (en) 2006-07-25 2010-10-26 Abbott Laboratories Methods of manufacturing crystalline forms of rapamycin analogs
US7812032B2 (en) 2006-07-25 2010-10-12 Abbott Laboratories Crystalline forms of rapamycin analogs
WO2008024626A2 (en) 2006-08-21 2008-02-28 Innovational Holdings Llc Bioresorbable stent with extended in vivo release of anti-restenotic agent
WO2008033956A2 (en) 2006-09-13 2008-03-20 Elixir Medical Corporation Macrocyclic lactone compounds and methods for their use
US20080065192A1 (en) 2006-09-13 2008-03-13 Medtronic Vascular, Inc. Compliance Graded Stent
WO2008033603A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices having alloy compositions
US20080071358A1 (en) 2006-09-18 2008-03-20 Boston Scientific Scimed, Inc. Endoprostheses
WO2008039749A2 (en) 2006-09-25 2008-04-03 Surmodics, Inc. Multi-layered coatings and methods for controlling elution of active agents
WO2008042909A2 (en) 2006-10-02 2008-04-10 Micell Technologies Inc. Surgical sutures having increased strength
EP1913960A1 (en) 2006-10-19 2008-04-23 Albert Schömig Coated implant
EP1916006A1 (en) 2006-10-19 2008-04-30 Albert Schömig Implant coated with a wax or a resin
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
US20080097591A1 (en) 2006-10-20 2008-04-24 Biosensors International Group Drug-delivery endovascular stent and method of use
US20080098178A1 (en) 2006-10-23 2008-04-24 Veazey Judson E Data storage on a switching system coupling multiple processors of a computer system
CA2667228C (en) 2006-10-23 2015-07-14 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US20080175887A1 (en) 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
WO2008067531A2 (en) 2006-11-30 2008-06-05 Smith & Nephew, Inc. Fiber reinforced composite material
CA2672496A1 (en) 2006-12-13 2008-06-19 Angiotech Pharmaceuticals, Inc. Medical implants with a combination of compounds
WO2008076383A2 (en) * 2006-12-18 2008-06-26 Med Institute Inc. Stent graft with releasable therapeutic agent
US8114466B2 (en) 2007-01-03 2012-02-14 Boston Scientific Scimed, Inc. Methods of applying coating to the inside surface of a stent
CN101711137B (zh) 2007-01-08 2014-10-22 米歇尔技术公司 具有可生物降解层的支架
US20130150943A1 (en) * 2007-01-19 2013-06-13 Elixir Medical Corporation Biodegradable endoprostheses and methods for their fabrication
CN101972492B (zh) 2007-01-21 2014-12-10 汉莫堤克股份有限公司 治疗体通道狭窄和预防危险的再狭窄的医学产品
US7745566B2 (en) 2007-01-23 2010-06-29 Ferro Corporation Methods for the purification of polymers
US7887830B2 (en) 2007-02-27 2011-02-15 Boston Scientific Scimed, Inc. Medical devices having polymeric regions based on styrene-isobutylene copolymers
WO2008115405A2 (en) 2007-03-16 2008-09-25 Sti Medicals Systems, Llc A method of image quality assessment to procuce standardized imaging data
US7815962B2 (en) 2007-03-22 2010-10-19 Medtronic Vascular, Inc. Coated stent with evenly distributed therapeutic agent
WO2008124634A1 (en) 2007-04-04 2008-10-16 Massachusetts Institute Of Technology Polymer-encapsulated reverse micelles
US20080249605A1 (en) * 2007-04-04 2008-10-09 Vipul Dave Bioabsorbable Polymer, Non-Bioabsorbable Metal Composite Stents
EP2146758A4 (en) 2007-04-17 2012-11-21 Micell Technologies Inc STENTS WITH BIODEGRADABLE LAYERS
US9433516B2 (en) 2007-04-17 2016-09-06 Micell Technologies, Inc. Stents having controlled elution
EP2146707A2 (en) 2007-05-03 2010-01-27 Abraxis BioScience, LLC Methods and compositions for treating pulmonary hypertension
US7952706B2 (en) 2007-05-17 2011-05-31 Prescient Medical, Inc. Multi-channel fiber optic spectroscopy systems employing integrated optics modules
GB0709517D0 (en) 2007-05-17 2007-06-27 Queen Mary & Westfield College An electrostatic spraying device and a method of electrostatic spraying
WO2008148013A1 (en) 2007-05-25 2008-12-04 Micell Technologies, Inc. Polymer films for medical device coating
US7922760B2 (en) 2007-05-29 2011-04-12 Abbott Cardiovascular Systems Inc. In situ trapping and delivery of agent by a stent having trans-strut depots
US20090068266A1 (en) 2007-09-11 2009-03-12 Raheja Praveen Sirolimus having specific particle size and pharmaceutical compositions thereof
US20090076446A1 (en) 2007-09-14 2009-03-19 Quest Medical, Inc. Adjustable catheter for dilation in the ear, nose or throat
US9248219B2 (en) 2007-09-14 2016-02-02 Boston Scientific Scimed, Inc. Medical devices having bioerodable layers for the release of therapeutic agents
CN101842362A (zh) 2007-09-27 2010-09-22 沃尔特及伊莱萨霍尔医学研究院 苯并噻唑化合物
US8709071B1 (en) 2007-09-28 2014-04-29 Abbott Cardiovascular Systems Inc. Stent with preferential coating
JP5114788B2 (ja) 2007-09-28 2013-01-09 三菱重工業株式会社 リチウム二次電池
US20090105687A1 (en) 2007-10-05 2009-04-23 Angioscore, Inc. Scoring catheter with drug delivery membrane
DK2214646T3 (da) 2007-10-05 2021-10-04 Univ Wayne State Dendrimers for sustained release of compounds
US20090105809A1 (en) 2007-10-19 2009-04-23 Lee Michael J Implantable and lumen-supporting stents and related methods of manufacture and use
US20100298928A1 (en) 2007-10-19 2010-11-25 Micell Technologies, Inc. Drug Coated Stents
US9987399B2 (en) 2007-10-30 2018-06-05 Nanyang Technological University Non-biodegradable stent comprising a biodegradable coating and method of coating the same
US8642062B2 (en) 2007-10-31 2014-02-04 Abbott Cardiovascular Systems Inc. Implantable device having a slow dissolving polymer
US20090111787A1 (en) 2007-10-31 2009-04-30 Florencia Lim Polymer blends for drug delivery stent matrix with improved thermal stability
CN101161300B (zh) 2007-11-27 2011-03-16 北京美中双和医疗器械有限公司 三氧化二砷药物洗脱支架及其制备方法
US20090202609A1 (en) 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
WO2009096822A1 (en) 2008-01-30 2009-08-06 Micromuscle Ab Drug delivery devices and methods and applications thereof
US20100042206A1 (en) 2008-03-04 2010-02-18 Icon Medical Corp. Bioabsorbable coatings for medical devices
WO2009111709A2 (en) 2008-03-06 2009-09-11 Boston Scientific Scimed, Inc. Balloon catheter devices with solvent-swellable polymer
WO2009113605A1 (ja) 2008-03-12 2009-09-17 アンジェスMg株式会社 薬剤溶出型カテーテル及びその製造方法
US8951545B2 (en) 2008-03-28 2015-02-10 Surmodics, Inc. Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
CA2721832C (en) 2008-04-17 2018-08-07 Micell Technologies, Inc. Stents having bioabsorbable layers
US8557273B2 (en) 2008-04-18 2013-10-15 Medtronic, Inc. Medical devices and methods including polymers having biologically active agents therein
US20110143429A1 (en) 2008-04-30 2011-06-16 Iksoo Chun Tissue engineered blood vessels
WO2009136586A1 (ja) 2008-05-08 2009-11-12 新日鐵化学株式会社 有機電界発光素子用化合物及び有機電界発光素子
US8298607B2 (en) 2008-05-15 2012-10-30 Abbott Cardiovascular Systems Inc. Method for electrostatic coating of a medical device
US7865562B2 (en) 2008-05-20 2011-01-04 International Business Machines Corporation Selecting email signatures
EP2131614B1 (en) 2008-05-30 2014-01-01 Alcatel Lucent Method for transmitting broadcast services in a radiocommunication cellular network through a femto base station, as well as corresponding femto base station
US20090297578A1 (en) 2008-06-03 2009-12-03 Trollsas Mikael O Biosoluble coating comprising anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders
US8206635B2 (en) * 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
JP5841708B2 (ja) 2008-07-01 2016-01-13 日東電工株式会社 表面被覆微粒子の医薬組成物
US7770466B2 (en) 2008-07-02 2010-08-10 Abbott Cardiovascular Systems Inc. Method for measuring stent dislodgement force
JP4557061B2 (ja) 2008-07-11 2010-10-06 トヨタ自動車株式会社 ハイブリッド自動車およびその制御方法
JP2011528275A (ja) 2008-07-17 2011-11-17 ミセル テクノロジーズ,インク. 薬物送達医療デバイス
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
JP2010052503A (ja) 2008-08-27 2010-03-11 Kawano Terukazu 船舶用エンジン
US20100055145A1 (en) 2008-08-29 2010-03-04 Biosensors International Group Stent coatings for reducing late stent thrombosis
WO2010024898A2 (en) 2008-08-29 2010-03-04 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US8367090B2 (en) 2008-09-05 2013-02-05 Abbott Cardiovascular Systems Inc. Coating on a balloon comprising a polymer and a drug
WO2010033482A1 (en) 2008-09-19 2010-03-25 Innovative Surface Technologies, Inc. Drug eluting superhydrophobic coatings
JP2012504032A (ja) 2008-09-29 2012-02-16 スターリング ヴァスキュラー システムズ インコーポレイテッド 薬剤溶出ステント及びその製造方法
US8535655B2 (en) * 2008-10-10 2013-09-17 Polyactiva Pty Ltd. Biodegradable polymer—bioactive moiety conjugates
CA2743491C (en) 2008-11-11 2016-10-11 Zelton Dave Sharp Inhibition of mammalian target of rapamycin
AU2009316588B2 (en) 2008-11-21 2014-09-11 Stout Medical Group, L.P. Reinforced biologic material
WO2010075590A2 (en) 2008-12-26 2010-07-01 Battelle Memorial Institute Medical implants and methods of making medical implants
US8834913B2 (en) 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
US9572692B2 (en) 2009-02-02 2017-02-21 Abbott Cardiovascular Systems Inc. Bioabsorbable stent that modulates plaque geometric morphology and chemical composition
US20100198330A1 (en) * 2009-02-02 2010-08-05 Hossainy Syed F A Bioabsorbable Stent And Treatment That Elicits Time-Varying Host-Material Response
EP2391401A2 (en) * 2009-02-02 2011-12-07 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Crystalline drug-containing coatings
CA2756388C (en) 2009-03-23 2015-10-27 Micell Technologies, Inc. Biodegradable polymers with low acidic impurity
EP2411083A4 (en) 2009-03-23 2013-11-13 Micell Technologies Inc MEDICAL DEVICE FOR DELIVERY OF MEDICAMENT
CA2756307C (en) * 2009-03-23 2017-08-08 Micell Technologies, Inc. Peripheral stents having layers and reinforcement fibers
CN102481195B (zh) 2009-04-01 2015-03-25 米歇尔技术公司 涂覆支架
US20110301697A1 (en) 2009-04-10 2011-12-08 Hemoteq Ag Manufacture, method and use of drug-eluting medical devices for permanently keeping blood vessels open
US9492587B2 (en) 2009-04-13 2016-11-15 Abbott Cardiovascular Systems Inc. Stent made from an ultra high molecular weight bioabsorbable polymer with high fatigue and fracture resistance
US20100285085A1 (en) 2009-05-07 2010-11-11 Abbott Cardiovascular Systems Inc. Balloon coating with drug transfer control via coating thickness
AU2010249683B2 (en) 2009-05-18 2015-06-25 Dose Medical Corporation Drug eluting ocular implant
WO2010136604A1 (en) 2009-05-29 2010-12-02 Dsm Ip Assets B.V. Transfer matrix for transferring a bioactive agent to body tissue
EP2266507B1 (de) 2009-06-22 2015-07-29 Biotronik VI Patent AG Stent mit verbessertem Stentdesign
US9327060B2 (en) 2009-07-09 2016-05-03 CARDINAL HEALTH SWITZERLAND 515 GmbH Rapamycin reservoir eluting stent
US8039147B2 (en) 2009-08-27 2011-10-18 Sb Limotive Co., Ltd. Rechargeable secondary battery having improved safety against puncture and collapse
WO2011044533A2 (en) * 2009-10-09 2011-04-14 Specialized Vascular Technologies, Inc. Coating system and method for drug elution management
EP2531140B1 (en) 2010-02-02 2017-11-01 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
WO2011119607A2 (en) * 2010-03-24 2011-09-29 The Board Of Trustees Of The University Of Illinois Viscoelastic ink for direct writing of hydrogel structures
CA2793832C (en) 2010-03-25 2018-09-18 Lixiao Wang Drug releasing coatings for medical devices
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
WO2011123798A2 (en) * 2010-04-01 2011-10-06 The Johns Hopkins University Three-dimensional scaffolds, methods for fabricating the same, and methods of treating a peripheral nerve or spinal or spinal cord injury
US20110257732A1 (en) 2010-04-16 2011-10-20 Micell Technologies, Inc. Stents having controlled elution
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
EP2593039B1 (en) 2010-07-16 2022-11-30 Micell Technologies, Inc. Drug delivery medical device
US9636309B2 (en) 2010-09-09 2017-05-02 Micell Technologies, Inc. Macrolide dosage forms
US20120150275A1 (en) * 2010-12-10 2012-06-14 Micropen Technologies Corporation Stents and methods of making stents
US8974622B2 (en) 2010-12-28 2015-03-10 Boston Scientific Scimed, Inc. Composite ePTFE-silicone covering for stent
WO2012092504A2 (en) 2010-12-30 2012-07-05 Micell Technologies, Inc. Nanoparticle and surface-modified particulate coatings, coated balloons, and methods therefore
WO2012097381A1 (en) 2011-01-14 2012-07-19 Biomerix Corporation At least partially resorbable reticulated elastomeric matrix elements and methods of making same
US20120323311A1 (en) 2011-04-13 2012-12-20 Micell Technologies, Inc. Stents having controlled elution
TW201311226A (zh) * 2011-05-06 2013-03-16 Ind Tech Res Inst 生物可吸收血管支架之製造方法
US9446172B2 (en) 2011-05-10 2016-09-20 Abbott Cardiovascular Systems Inc. Modification of bioabsorbable stent to reduce thrombogenecity
WO2012166819A1 (en) 2011-05-31 2012-12-06 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
JP6505438B2 (ja) 2011-06-30 2019-04-24 エリクシアー メディカル コーポレイション 生分解性内部人工器官およびその作製方法
CA2841360A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US20140257465A1 (en) * 2011-08-12 2014-09-11 Micell Technologies, Inc. Stents having controlled elution
WO2013059509A1 (en) 2011-10-18 2013-04-25 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
WO2013177211A1 (en) 2012-05-21 2013-11-28 Micell Technologies, Inc. Safe drug eluting stent with absorbable coating
US9090029B2 (en) 2012-02-06 2015-07-28 Warsaw Orthopedic, Inc. Pultrusion process for preparing composites having low percentage of fibers and articles made from same
US8859088B2 (en) 2012-04-16 2014-10-14 Auburn University Minimal weight composites using open structure
WO2013173657A1 (en) 2012-05-16 2013-11-21 Micell Technologies, Inc. Low burst sustained release lipophilic and biologic agent compositions
US8968387B2 (en) * 2012-07-23 2015-03-03 Abbott Cardiovascular Systems Inc. Shape memory bioresorbable polymer peripheral scaffolds
KR101231197B1 (ko) 2012-09-20 2013-02-07 썬텍 주식회사 고분자 스텐트
JP2015533305A (ja) 2012-10-18 2015-11-24 ミセル テクノロジーズ,インク. 薬物送達医療デバイス
US9744058B2 (en) * 2013-02-14 2017-08-29 Abbott Cardiovascular Systems Inc. Methods of treatment directed to neointimal proliferation generated by endothelial shear stress patterns from drug-eluting bioresorbable vascular scaffold implantation
WO2014165264A1 (en) 2013-03-12 2014-10-09 Micell Technologies, Inc. Bioabsorbable biomedical implants
WO2014176451A1 (en) * 2013-04-24 2014-10-30 Trustees Of Tufts College Bioresorbable biopolymer stent
KR102079613B1 (ko) 2013-05-15 2020-02-20 미셀 테크놀로지즈, 인코포레이티드 생흡수성 생체의학적 임플란트
EP3033053A4 (en) * 2013-08-16 2017-04-05 Amaranth Medical PTE Bioresorbable scaffold for treatment of bifurcation lesion
US9510976B2 (en) * 2014-04-29 2016-12-06 Abbott Cardiovascular Systems Inc. Devices and methods for treatment of the Eustachian tube and sinus cavity
WO2015181826A1 (en) 2014-05-27 2015-12-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Crystalline coating and release of bioactive agents
US11628077B2 (en) * 2016-10-31 2023-04-18 Razmodics Llc Post deployment radial force recovery of biodegradable scaffolds

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