JP6275052B2 - アプタマー法 - Google Patents

アプタマー法 Download PDF

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Publication number
JP6275052B2
JP6275052B2 JP2014557118A JP2014557118A JP6275052B2 JP 6275052 B2 JP6275052 B2 JP 6275052B2 JP 2014557118 A JP2014557118 A JP 2014557118A JP 2014557118 A JP2014557118 A JP 2014557118A JP 6275052 B2 JP6275052 B2 JP 6275052B2
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Japan
Prior art keywords
probe
analyte
aptamer
panel
hole
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Japanese (ja)
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JP2015508893A5 (enExample
JP2015508893A (ja
Inventor
ジョン ターナー,ダニエル
ジョン ターナー,ダニエル
ジョージ フォーダム,ダニエル
ジョージ フォーダム,ダニエル
チャールズ ジル,ロジャー
チャールズ ジル,ロジャー
ギャビン ブラウン,クライブ
ギャビン ブラウン,クライブ
レイド,スチュアート
アンソニー クラーク,ジェームス
アンソニー クラーク,ジェームス
ホワイト,ジェームス
Original Assignee
オックスフォード ナノポール テクノロジーズ リミテッド
オックスフォード ナノポール テクノロジーズ リミテッド
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/36Assays involving biological materials from specific organisms or of a specific nature from bacteria from Actinomyces; from Streptomyces (G)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/49Platelet-derived growth factor [PDGF]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433Serine endopeptidases (3.4.21)
    • G01N2333/96441Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96463Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
JP2014557118A 2012-02-15 2013-02-14 アプタマー法 Active JP6275052B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261599240P 2012-02-15 2012-02-15
US61/599,240 2012-02-15
PCT/GB2013/050348 WO2013121201A1 (en) 2012-02-15 2013-02-14 Aptamer method

Publications (3)

Publication Number Publication Date
JP2015508893A JP2015508893A (ja) 2015-03-23
JP2015508893A5 JP2015508893A5 (enExample) 2016-03-31
JP6275052B2 true JP6275052B2 (ja) 2018-02-07

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Family Applications (1)

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JP2014557118A Active JP6275052B2 (ja) 2012-02-15 2013-02-14 アプタマー法

Country Status (8)

Country Link
US (3) US10739341B2 (enExample)
EP (1) EP2815235B1 (enExample)
JP (1) JP6275052B2 (enExample)
CN (1) CN104220874B (enExample)
AU (1) AU2013220156B2 (enExample)
CA (1) CA2864035C (enExample)
IN (1) IN2014DN06796A (enExample)
WO (1) WO2013121201A1 (enExample)

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Also Published As

Publication number Publication date
CA2864035C (en) 2021-05-18
CA2864035A1 (en) 2013-08-22
US11685922B2 (en) 2023-06-27
AU2013220156A1 (en) 2014-09-18
IN2014DN06796A (enExample) 2015-05-22
EP2815235A1 (en) 2014-12-24
CN104220874B (zh) 2017-05-24
WO2013121201A1 (en) 2013-08-22
US10739341B2 (en) 2020-08-11
US20230392157A1 (en) 2023-12-07
AU2013220156B2 (en) 2018-08-09
CN104220874A (zh) 2014-12-17
US20210018500A1 (en) 2021-01-21
JP2015508893A (ja) 2015-03-23
US20150177237A1 (en) 2015-06-25
EP2815235B1 (en) 2020-04-15

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